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[Function of the respiratory system in miners with chronic regional hypobaric hypoxia and hypothermia].

The role of meteotropic factors (low atmospheric pressure and cold climate) in the development of functional disorders of respiratory system was studied for miners of the North-East region of the USSR. Regularities in forming external respiration dysfunctions during adaptation of migrating population and development of dust pathology are demonstrated. It was found that general adaptation syndrome in miners exposed to chronic hypobaric hypoxia and hypothermia is characterized by development of hyperventilation syndrome, leading to increase in dust load and moderate mobilization of respiratory tissue. Early failure of compensatory processes and forming of marked hyperventilation syndromes, an increase in pulmonary elastic draught and mobilization of respiratory tissue are observed in dust pathology in the analyzed conditions.

Adaptation, Physiological↗

Replantation service in Helsinki University Central Hospital 1980-1985.

A replantation service is a routine part of medical services. The best results are obtained when the work is centralized. In Finland five university hospitals have a replantation service. In the Helsinki University Central Hospital, 94 severed parts of the upper limb were replanted/revascularized in 1980-85. The amputation injury requiring replantation was most often a thumb avulsed by the driving axle of a tractor. The patients came from all over the country, and the short time span between the initial injury and admission to hospital--2.4 hours an average in 1985--shows that transport of these patients is not a problem in Finland. The mean duration of surgery was 6.9 hours. Most of the operations took place in the late afternoon, evening or at night. 16% of the cases needed immediate reoperation because of vascular problems. Later, over 40% of the cases underwent secondary procedures. Most of the patients returned to their former employment. In long-term follow-up, however, nine out of ten patients reported that the replanted organ was intolerant to cold. Therefore, with the exception of the thumb, single finger replantation should not be a routine procedure in a cold climate such as that encountered in Finland. A replantation service requires a minimum of four surgeons qualified in plastic surgery or hand surgery. The operating theatre will be in use through the night. Nurses, physiotherapists and occupational therapists must be specially trained. The surgeon must be prepared to perform multiple reconstructive procedures, both immediately and later on.

Adult↗

The heart and the cold.

This review presents current epidemiological evidence indicating that a cold environment contributes to increased cardiovascular, especially coronary heart disease, morbidity and mortality, and examines the factors which might explain these findings. Most epidemiological studies have revealed a peak in the coronary morbidity and mortality during the cold season, and a strong negative correlation between the air temperature or its drop and the occurrence of coronary heart disease. These associations could be apparent, indirect or causative. A small part of the increased coronary morbidity and mortality could be due to, for example erroneous recording of cause of death (eg. death due to respiratory diseases). Part of the increased coronary manifestations of cold seem to be due to changes in living circumstances and habits associated with cold. The gradual development of hypothermia among people living in poor socio-economic conditions may lead to a disastrous chain of events. Snowfalls and storms associated with cold weather may increase the incidence of cardiac complications by exposing people to exceptional physical efforts and circumstances. Some of the effects of cold are direct: cold increases the myocardial oxygen demand by increasing sympathetic stimulation, systolic blood pressure and cardiac diastolic pressure and volume. At the same time the myocardial oxygen supply may be impeded by coronary vasoconstriction especially in vessels damaged by atherosclerosis. In addition to these short term effects cold may augment atherosclerosis for example by increasing blood pressure and the blood concentration of cholesterol, catecholamines, corticoids and thrombocytes during the cold season.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗

Growth and development of winter tick, Dermacentor albipictus, on moose, Alces alces.

Moose, Alces alces, were infested with 21,000 or 42,000 larval Dermacentor albipictus at the end of September. Larvae grew rapidly and molted to the nymphal stage 10-22 days after infestation. The nymphal stage lasted approximately 3 mo until mid-January and was characterized by a diapause. The diapause is likely an adaptation to survival in cold climates. Nymphs started engorging in January and adults were seen with increasing abundance from mid-January to March and April. The minimum parasitic period was 175 days. Growth of larvae and nymphs was similar on moose given different numbers of larvae and was generally similar between a moose infested in November and moose infested earlier. Dimensions and stages of development throughout the parasitic phase are given. Game enforcement officers are encouraged to use these data for determination of season of death of moose.

Analysis of Variance↗

Factors affecting preconditioning of Trichinella spiralis nativa larvae in musculature to low temperatures.

The influence of preconditioning temperature, length of the preconditioning period, host and age of the infection on the survival of Trichinella spiralis nativa larvae in musculature to low temperature refrigeration was investigated. Dogs, foxes, ferrets, mink and guinea pigs were infected with a T. spiralis nativa isolate, killed at various times postinfection, preconditioned at temperature of -10 degrees C, -15 degrees C or -20 degrees C for varying periods of time prior to low temperature refrigeration and subsequent pepsin digestion to determine survival of larvae. The preconditioning temperature played an important role in the subsequent survival of larvae in musculature at low refrigeration temperatures. Under the conditions of this study, survival of larvae was greater as the preconditioning temperature became lower. The minimum period of preconditioning required had an inverse relationship with the refrigeration temperature. Preconditioning of the T. spiralis nativa isolate used occurred in the musculature of guinea pigs, foxes, ferrets, mink and dogs with larvae surviving longer in vulpine and canine musculature than in the other hosts studied. Age of the infection was not a major factor in the survival of preconditioned larvae in musculature at low refrigeration temperatures although survival was slightly longer in older infections.

Animals↗

Echinococcosis multilocularis in Turkey.

We present 20 new cases of Echinococcosis multilocularis (EM) and have also reviewed all 137 previously reported cases from Turkey. The total number of cases is now 157 up until the end of 1983. Of 146 cases with information on their place of occurrence, 133 (91%) were from eastern and central parts of Turkey or the region of the Black Sea where the cold climate is predominant. This area should be considered as part of the geographic distribution of Echinococcus multilocularis which extends from the Caucasian Republics (Azerbaijan and Georgian S.S.R.) to Siberia in the Soviet Union. EM is more frequent among the people involved in raising livestock in the rural areas of Turkey. Most of the cases (76%) were between the ages of 30 and 50; 53% were males. One hundred and thirty nine cases (92%) were liver infections, and most of the cases (60%) were clinically diagnosed as liver tumour.

Adolescent↗