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At least 433 records · Page 24Linked to original sources
PubMed1990

[Modern cosmetic agents and evidence of their function].

Fluorometers modified by quartz light conductors allow the recording of the skin-intrinsic fluorescence. Signals assigned to the aromatic amino acids permit a prognosis concerning the sensitivity of untreated skin to light and the sunscreen factor to be expected after the application of UV filters. We discuss the microdistribution and skin penetration of UV filters and describe the utilization of the image analysis technique both for the count and size determination of fluorescent sebaceous glands and for the quantification of the effects of antiperspirants. Based both on the selective increase of efficacy of deodorant soaps, analytically controlled, and on the differences of the deodorizing effects found in various test groups, we discuss the possibilities of improving deodorants.

Acne Vulgaris↗
PubMed1990

A case of hyperhidrosis successfully treated with 20% aluminium chloride hexahydrate in 95% ethyl alcohol.

A 23-year old medical student presented with a history of excessive sweating from the palms and soles from the age of 16 years. He tried Propranolol but the relief lasted only 30 minutes and he developed breathing difficulty. He applied 20% Aluminium Chloride hexahydrate in 95% Alcohol during the nights and found a definite reduction in sweating. This method appears to be cheap, safe and convenient.

Adult↗
PubMed1988

Axillary hyperhidrosis. Local treatment with aluminium-chloride hexahydrate 25% in absolute ethanol with and without supplementary treatment with triethanolamine.

In a randomized, double-blind, half-sided experiment, 30 volunteers were treated in both armpits with aluminium chloride hexahydrate 25% in ethanol. In order to neutralize pH and thus reduce the skin irritation, post-treatment was performed in one armpit with triethanolamine 50% in ethanol. The sweat production was measured after physical labour by means of a combined colorimetric/gravimetric method. The combined treatment with aluminium chloride hexahydrate and triethanolamine was found to be statistically significantly (p less than 0.01) less irritating to the skin, but also statistically significantly (p less than 0.01) less effective than treatment with aluminium chloride hexahydrate alone. However, the reduction in the effect of the treatment was not of a sufficient extent as to be noticed by the volunteers themselves.

Adult↗
PubMed1989

Unique reactions of scrotal skin to topical agents.

Topical agents that do not produce irritant reaction elsewhere on the skin readily produce irritant dermatitis and even ulceration when applied to scrotal skin. As Shelley and Shelley state: "The scrotum must be recognized as a skin area with remarkable permeability. It provides a unique percutaneous doorway for the entrance of drugs into the circulation and is thus uniquely susceptible to toxic and irritant agents."

Administration, Cutaneous↗
PubMedDate not supplied

[Antiperspirants and deodorants--ingredients and evaluation].

Antitranspirants and deodorants gain more and more interest. Aluminium chlorohydrate and aluminium zirkonium tetrachlorohydrate glycine complex are the most frequently used active ingredients in commercial antitranspirants today. Aluminium chloride and propantheline bromide, the anticholinergic substance, are important alternatives although less common. Active ingredients of deodorants are mainly perfumes or bactericidal/bacteriostatic substances, such as triclosan. In addition, there are substances which are meant to bind offending smells (e.g. zinc ricinoleate) or to influence the skin surface pH (e.g. triethyl citrate). As in the cosmetics industry in general, both safety and efficacy of a product are major parameters in the experimental and clinical evaluation. Establishment of efficacy is based on olfactory tests in model situations as well as on the detection of associated effects (e.g. influence on cutaneous microflora).

Astringents↗
PubMed1989

Hyperhidrosis: a management dilemma.

Hyperhidrosis is excessive sweating in response to psychological stress and emotional stimuli. The sweat is usually limited to the palms, soles, and axillae, and is greatly accentuated by mental stimuli rather than temperature and exercise. The severity is such that for many, sweating has become socially and emotionally devastating and may predispose to other cutaneous diseases. More than 60 research papers on eccrine glands and sweating have been published since 1978. Little progress, however, has been made on the control of hyperhidrosis, and the process remains a treatment dilemma among both family physicians and dermatologists. The many treatment modalities documented in the literature have been for the most part unsuccessful or unacceptable. This report describes the use of phenoxybenzamine, an alpha-adrenergic antagonist, for control of excessive sweating in two patients. After a trial of topical medication, phenoxybenzamine is useful for the reduction of sweating to an acceptable level.

Administration, Topical↗
PubMed1987

Antiperspirants and deodorants.

Since the introduction of the first commercial deodorant and antiperspirant, use of underarm products has assumed an increasing role in individual personal care habits. This paper reviews the physiology of human perspiration and describes the function and classification of antiperspirants and deodorants.

Astringents↗