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[Pelvic actinomycosis in menopausal patient, case review].

Pelvic actinomycosis is a granulomatous chronic illness due to anaerobic, gram-positive, branching filamentous bacteria (Actinomyces israelii), this and other species of actinomyces occur in the normal flora of the gastrointestinal and genital tract in humans. Infection is associated in women using an IUD (Intrauterine device) for long periods and it has the characteristic of simulate malignant diseases causing most of the times wrong preoperative diagnosis. We analyzed a postmenopausal patient who was treated surgically without specific diagnosis, then by anatomo-pathologic study of the specimen the result was actinomycosis. The main purpose to obtain the correct preoperative diagnosis is because we have to use antibiotics in the treatment and it may reduce the frequency of radical surgeries.

Actinomycosis↗

[Actinomycosis of the ovary as a cause of cachexia in a young patient].

The authors describe the case of a 40-year-old female patient treated for prolonged periods unsuccessfully with several antibiotics on account of a febrile condition of obscure aetiology and subsequently repeatedly subjected to laparotomy on account of intra-abdominal abscesses. The cause of the fever, abdominal pain and gradual cachectization was an abdominal form of actinomycosis. After establishment of the diagnosis the patient was successfully treated by long-term penicillin administration and recovered completely. The authors discuss experience reported in the literature and therapeutic possibilities in actinomycosis.

Actinomycosis↗

[Actinomycosis of the large bowel].

Actinomycosis is an infrequent chronic infectious disease. In most cases the diagnosis is made post-operatively because of its unusual clinic presentation. We report three cases of actinomycosis involving large bowel. Based on current literature we review the diagnosis and therapeutic considerations. These should be helpful to the surgeons confronting the rare disease.

Actinomycosis↗

[Efficacy of doxycycline in thoracic actinomycosis: a case report].

The authors present a case of thoracic actinomycosis in a 32 year-old man with a history of cervico-facial actinomycosis. Diagnosis was made by bacterial examination of purulent drainage from sternal wound showing typical sulfures granules. One year course of doxycycline gives clinical and radiological improvement.

Actinomycosis↗

Pelvic actinomycosis in a postmenopausal patient with systemic lupus erythematosus mimicking ovarian malignancy: case report and review of the literature.

Pelvic actinomycosis is a chronic granulomatous suppurative disease caused by an anaerobic gram-positive organism Actinomyces israelii usually associated with intrauterine devices. Systemic lupus erythematosus is an autoimmune disorder associated with multiple primary and drug-related immunological defects that predispose patients to infections. The combination of both diseases in a postmenopausal patient is a rare occurrence. A case of a pelvic mass in a 49-year-old postmenopausal patient with systemic lupus erythematosus treated with immunosuppressive therapy for two years is presented. The patient presented with lower abdominal pain to the gynecology clinic and was found to have a pelvic tumor. She had no history of intrauterine device use. Histopathologic examination of the laparotomy specimen revealed pelvic actinomycosis.

Abdominal Pain↗

Actinomycosis of submandibular gland: an unusual presentation.

An unusual presentation of oro-facial actinomycosis, mimicking the clinical appearance of a malignant lesion is reported. The patient, a 74-year-old female, presented with a right submandibular mass, which slowly grew in size over a period of about 2 months, and a modest dysphagia. A painless cervical mass was palpable over the submandibular region. The rhino-pharyngo-laryngeal region, explored by flexible fiberoptic examination, was normal. At ultrasonography, a 2x2 cm infiltrating dyshomogeneous mass, involving the right submandibular gland, was visible. No connection with adjacent organs was found. There was no associated cervical lymphoadenopathy. Ultrasound-guided fine-needle aspiration cytology, performed on lesion, revealed no evidence of malignancy. The presence of characteristic colonies of actinomyces infection was found. The patient was treated initially with tetracycline chloridrate 100 mg: 1 tablet every 12 hours for 7 weeks, but a repeat ultrasonography showed no resolution. A further fine-needle aspiration cytology showed no actinomyces infection in the specimen. The patient was treated with methylprednisolone, 20 mg every 24 hours, for 5 days. After steroid treatment, the patient has been well and, upon repeat ultrasonography, total resolution of the submandibular lesion was confirmed. In conclusion, the clinical presentation of cervicofacial actinomycosis is variable and may mimic a malignant lesion or chronic granulomatous infections. Diagnostic and therapeutic findings are discussed.

Actinomycosis↗

[Hepatic actinomycosis--pseudotumoral form].

Hepatic actinomycosis is a pretty rare anatomo-clinical entity that often induces a wrong pre-operative diagnosis. By presenting a case of hepatic actinomycosis, apparently primitive and diagnosed pre-operatively as a neoplastic lesion, the authors discuss the diagnosis and treatment of this disease, mentioning that in the solid, tumoral forms, the hepatic resection is necessary. The authors consider that the post-operative addition of antibiotherapy (mega doses of penicillin) is useful for the eradication of inflammatory residual hepatic parenchyma as well as for the cicatrisation of the parietal fistulae.

Actinomycosis↗

Abdominal actinomycosis presenting as a small-bowel obstruction.

A 48-year-old female, presented as a case of acute abdomen with a small-bowel obstruction and a palpable hypogastric mass, was urgently operated. Laparotomy revealed a tumor mass of unknown origin that included a loop of the small bowel by compressing it. Resection of the tumor including a portion of the large and small bowel was performed, and pathohistological examination revealed actinomycosis. The cause of abdominal actinomycosis in this patient could be the implantation of an intrauterine device nine years prior to the operation.

Abdomen↗

[A case of bronchial actinomycosis associated with bronchoscopically removed broncholith].

A 57-year-old woman with bronchial actinomycosis associated with broncholith is presented. She had suffered from fever and productive cough for 7 years. Her chest roentgenograms showed atelectasis of the middle lobe and calcification in the middle lobe bronchus. Bronchoscopic examination revealed a broncholith covered with pus and granulomatous tissue. The biopsy specimen revealed sulfur granules containing a partially calcified lesion, and it was diagnosed as actinomycosis. After treatment with antibiotics, the broncholith became movable, and it was removed bronchoscopically. Its shape was like a molding of the right middle lobe bronchus. We speculate that the growth of this broncholith partially resulted from chronic inflammation associated with actinomycelial infection.

Actinomycosis↗

[Cervico-facial actinomycosis--case reports].

In the article the authors made the review of actinomycosis bibliography. They also presented characteristic features infections enter ways, course of the disease, diagnostic tests and treatment methods. Two cases of face and neck actinomycosis were presented. All of them treated in Katowice-Ochojec Hospital ENT ward in last five years. Abnormal clinic symptoms made difficulty to put the diagnosis. Satisfactory results were achieved after set up final diagnosis and proper treatment.

Actinomycosis, Cervicofacial↗

[Presentation of a case of cervical actinomycosis versus Hodgkin lymphoma].

Actinomycosis is an unfrequent bacterian infection, that affects 50% of the cases in the cervical facial region. The evolution and clinical, anatomopathologic radiologic characteristic, and its presentation bring us to suspect another type of more frequent pathology: the neoplastic, that make very difficult its diagnosis. We present the case of a young patient affected by a cervical tumoration initially oriented as Hodgkin lymphoma that finally was diagnosed as cervical actinomycosis and treated with penicillin.

Actinomycosis↗

[Generalized actinomycosis in an 8-month-old child].

Generalized actinomycosis as well as other fungal lesions are typical for children with congenital or acquired immunodeficiencies. The present case of generalized actinomycosis developed against the background of the immunodeficiency resulting from dysplasia of the thymus and lymphoid tissue after chemotherapy of abdominal tumour.

Abdominal Neoplasms↗

Pelvic actinomycosis in pregnancy: a case report and review of the literature.

The first reported case in Thailand of pelvic actinomycosis during pregnancy is presented. It occurred in a 38-year-old Thai female with a history of IUD wearing for 2 years until the symptoms of intermittent lower abdominal pain. She had a history of postcoital bleeding at 16 weeks' pregnancy and bleeding per vagina during labor at 40 weeks' pregnancy. Speculum examination showed an irregular, friable, easily bleeding mass (3-4 cm in diameter). The specimens of the mass at the posterior fornix were obtained for culture and pathological examination. Right tubo-ovarian complex measured 10 x 4 x 4 centimeters in diameter, extending through the cul-de-sac to the vaginal canal at the posterior fornix, was identified during exploratory laparotomy. Low transverse cesarean section was performed. The pathological diagnosis was actinomycosis of right fallopian tube and ovary. The patient was treated with tetracycline.

Actinomycosis↗

Hepatic actinomycosis presenting as liver mass: case report and review of the literature.

Primary hepatic actinomycosis is an uncommon entity. We report the case of a young man with past history of an appendectomy who presented with fever, weight loss and a liver mass that was initially suspected to be neoplastic. Percutaneous liver biopsy revealed actinomyces-like organisms. The patient was treated with intravenous and oral penicillin with good therapeutic response. Review of the literature and correlation between hepatic actinomycosis and previous appendectomy are considered.

Actinomyces↗

Unusual case of resistant actinomycosis following facial trauma.

A case of actinomycosis is reported which appeared as a complication of a ski-pole injury of the face. A 16-year-old girl was treated for 10 years for resistant actinomycosis. She took long-term antimicrobial therapies, underwent repeated excisions, hyperbaric oxygen therapy, repeated skin grafting, immunological treatment, and free flap transfer. The conservative antibiotic treatment was complicated by mycosis and pseudomembranous colitis. After the defect healed up, satisfactory contour of the face was restored with additional free flap transfer. The patient has also been satisfied with the final aesthetic result. The authors highlight the importance of early diagnosis and proper antimicrobial treatment in combination with surgical excisions of granulation tissue preserving vital structures.

Actinomycosis, Cervicofacial↗

An unusual presentation of actinomycosis in a young woman, after surgery.

Actinomycosis is an unusual, chronic granulomatous disease. Actinomyces israelli has been found to be related to infectious processes in those patients with affected skin integrity leading to abscess formation, fistulae or mass lesions. Actinomycosis mainly presents in three forms cervicofacial (50%), abdominal (20%) and thoracic (15%). Pelvic cases have been rarely reported and are usually associated with the use of intrauterine devices. We describe a case of a 23 y/o female without history of intrauterine device use, who was admitted with an ovarian cyst following an appendectomy. An ovarian abscess was drained. The pathology showed a granuloma and focal sulfur granules like particles compatible with Actinomyces. This is a case of pelvic Actinomyces, not related to the use of an intrauterine device.

Abdominal Abscess↗