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PubMed2001

Syntactic and semantic processing in the healthy and aphasic human brain.

A syntactic and a semantic task were performed by German-speaking healthy subjects and aphasics with lesions in the dominant left hemisphere. In both tasks, pictures of objects were presented that had to be classified by pressing buttons. The classification was into grammatical gender in the syntactic task (masculine or feminine gender?) and into semantic category in the semantic task (man- or nature made?). Behavioral data revealed a significant Group by Task interaction, with aphasics showing most pronounced problems with syntax. Brain event-related potentials 300-600 ms following picture onset showed different task-dependent laterality patterns in the two groups. In controls, the syntax task induced a left-lateralized negative ERP, whereas the semantic task produced more symmetric responses over the hemispheres. The opposite was the case in the patients, where, paradoxically, stronger laterality of physiological brain responses emerged in the semantic task than in the syntactic task. We interpret these data based on neuro-psycholinguistic models of word processing and current theories about the roles of the hemispheres in language recovery.

Adult↗
PubMed2001

Electronic submission of academic works: a survey of current editorial practices of radiologic journals.

Computers are nearly ubiquitous in academic medicine, and authors create and compile much of their work in the electronic environment, yet the process of manuscript submission often fails to utilize the advantages of electronic communication. The purpose of this report is to review the submission policies of major academic journals in the field of radiology and assess current editorial practices relating to electronic submission of academic works. The authors surveyed 16 radiologic journals that are indexed in the Index Medicus and available in our medical center library. They compared the manuscript submission policies of these journals as outlined in recent issues of the journals and the corresponding worldwide web sites. The authors compared the journals on the following criteria: web site access to instructions; electronic submission of text, both with regard to initial submission and final submission of the approved document; text hardcopy requirements; word processing software restrictions; electronic submission of figures, figure hardcopy requirements; figure file format restrictions; and electronic submission media. Although the trend seems to be toward electronic submission, there currently is no clear-cut standard of practice. Because all of the journals that accept electronic documents also require a hardcopy, many of the advantages gained through electronic submission are nullified. In addition, many publishers only utilize electronic documents after a manuscript has been accepted, thus utilizing the benefits of digital information in the printing process but not in the actual submission and peer-review process.

Humans↗
PubMed2000

Noun imageability and the temporal lobes.

We used positron emission tomography to investigate brain activity in response to hearing or reading nouns of varying imageability. Three experiments were performed. Activity increased with noun imageability in the left mid-fusiform gyrus, the lateral parahippocampal area in humans, and in the rostral medial temporal lobes close to or within perirhinal cortex. The left mid-fusiform activation has been observed in previous imaging studies of single word processing. Its functional significance was variously attributed to semantic processing, visual imagery, encoding episodic memories, or the integration of lexical inputs from different sensory modalities. These hypotheses are not mutually exclusive. The more rostral medial lobe response to noun imageability has not been observed previously. However, lesions in perirhinal cortex impair knowledge about objects in non-human primates, and bilateral rostral ventromedial temporal lobe potentials in response to object nouns were observed with human intracranial recordings. Imageable (object) nouns are learnt with reference to sensory experiences of living and non-living objects, whereas acquisition of the meaning of low imageable (abstract) nouns is more dependent on their context within sentences. Parahippocampal and perirhinal cortices are reciprocally connected with, respectively, second and third order sensory association cortices. We conclude that access to the representations of word meaning is dependent on heteromodal temporal lobe cortex, and that during the acquisition of object nouns one route is established through ventromedial temporal cortical regions that have reciprocal connections with all sensory association cortices.

Adult↗
PubMed1995

Evaluating graduate and undergraduate nursing students' computer skills to determine the need to continue teaching computer literacy.

1. INTRODUCTION. This descriptive study examined undergraduate and graduate nursing students' perceptions of their computer literacy skills to determine whether faculty should continue teaching basic computing skills in nursing programs. As in Bryson's study [1] the computer literate nurse is one who understands the concepts of hardware, software, and operating systems; who is able ot use the computer to learn; and who is able ot use such applications as word-processing, spreadsheets, and databases. Zeimer [2] predicted that by 1994 students entering nursing schools would be prepared to use computers and that further teaching of computer skills would not be needed. Some faculty, however, have felt that students are not entering nursing programs prepared to use computers. 2. TOOLS. A Level of Computer Experience (LCE) tool was developed to measure the computer literacy skills of students entering the first of three Masters' level nursing informatics courses over a six-year period. The instrument's 25 items determined experience with: operating systems, hardware, learning tools, applications, and information systems (IS) life cycle (design, selection, implementation, evaluation and project management). The instrument was modified for undergraduate students; this eliminated the items relating to the IS life cycle since these items reflect advanced skills. The resulting instrument was composed of the first 16 items of the original Level of Computer Experience tool. For each item, a four pint Likert scale allowed respondents to choose from the words "none," "some," "moderate," and "extensive" to describe their level of experience. For scoring purposes each word was assigned a numerical value as follows: none = 1, some = 2, moderate = 3, and extensive =4. 3. DATA. The LCE was administered to 65 sophomore nursing students and 74 graduate nursing informatics students. Undergraduate scored 4 items (use of microcomputer, use of IBM type computer, keyboard skills and use of WordPerfect). This score was above the 2 or 'some' experience level. Mean scores for all other items ranged between 1 and 2. Graduate informatics students also had higher mean scores for the 4 items. No mean scores reached the 'moderate' level for either group. One-way analysis of variances showed significant differences between the undergraduate and graduate students on the item concerning use of statistical packages. 4. CONCLUSIONS. In this population, both graduate and undergraduate nursing students continue to possess low levels of computer literacy skills. Since many students come into nursing programs without the capability of using information technology in practice, schools need to continue providing a way for students to obtain computer literacy skills.

Baltimore↗
PubMed1998

Levels of processing and single word priming in amnesic and control subjects.

This paper describes an experiment which examined how levels of processing (LOP) affected word fragment completion in a group of Wernicke-Korsakoff patients, a group of patients with closed head injury, and matched controls. The data showed that both the memory-impaired groups and the controls showed a LOP effect but that the effect was larger in controls. Data from other studies are reviewed and, in conjunction with the present findings, it is concluded that LOP effects obtained when memory-impaired individuals are tested using implicit memory tasks arise mainly from the contribution of lexical processing of targets and from contamination by explicit recollection.

Adult↗
PubMed2001

Cortical connectivity during word association search.

Cortical connectivity was studied in tasks of generating the use of words in comparison with reading aloud the same words. These tasks were used earlier in PET and high density ERP recordings studies (Posner and Raichle, 1997; Abdullaev and Posner, 1998), in which both the functional anatomy and the time course of cortical areas involved in word processing were described. The wavelet transforms of ERP records and the calculation of correlations between wavelet curves were used to reveal connections between cortical areas. Three stages of intracortical communications while task performance were found. These were: (1) the connections between right and left frontal and central areas which preceded stimulus delivery and persisted up to 180 ms after it; (2) the network connecting right and left frontal with left posterior temporal-parietal junction at 280-450 ms; and (3) communications between left and right temporal zones in 550-800 ms. The data are in good agreement with results of previous PET and ERP studies and supply the earlier findings with circuitry of cortical information transfer.

Adolescent↗
PubMed1997

One residency's experience with the electronic residency application service.

For medical students and residency programs alike, the residency application process is time-consuming. This paper examines one program's experience with a computerized system designed by the Association of American Medical Colleges (AAMC) to simplify and standardize the filing and receipt of applications over the Internet. A large-scale pilot test of the Electronic Residency Application Service (ERAS) was implemented in 1995-1996 for applicants to first-year residency positions in OB-GYN. Each student completed the computerized application, which was transmitted, along with other documents, to student-specified programs by the dean's office via the AAMC "electronic post office." ERAS will be extended to family practice residencies in 1997-1998. A major advantage of ERAS to residency programs is that materials were received in a well-organized, complete, and consistent format. Built-in filters allow grouping of applicants according to various criteria. Opening envelopes and filing documents is no longer necessary. Each student completes one application, and faculty write one letter of recommendation per student. Disadvantages of the 1995-1996 system related to the software, which had an inflexible interface and did not allow a spreadsheet view of the database. Personal statements and recommendation letters were often sent as unformatted ASCII text and were difficult to read. Dean's offices reported problems scanning documents such as transcripts and photographs. These problems led to resubmission of materials and receipt of duplicate copies. With the standard application format, ASCII-style personal statements and "generic" recommendation letters caused applicants to lose individuality. Specific recommendations to the AAMC for improving ERAS include providing a spreadsheet view, allowing students and faculty to write personal statements and letters in standard word processing formats, and allowing faculty to send unique letters to specific residency programs.

Computer Communication Networks↗
PubMed1998

Canopy computing: using the Web in clinical practice.

The rain forest canopy is a seamless web through which arboreal creatures efficiently move to reach the edible fruits without any attention to the individual trees. Individual health care computer systems are rich with patient data, but rather than a canopy linking all the trees in the forest, the data "fruit" come from a diverse forest of individual computer "trees"-laboratory systems, word processing systems, pharmacy systems, and the like. These different sources of patient information are difficult or impossible to reach by individual physicians, especially from their offices. The World Wide Web and other standardization technology provide physicians and their institutions the tools needed for seamless and secure access to their patients' data and to medical information, when and where they need it. We and others have adopted these tools to combine independent sources of clinical data. Physicians who assist in the purchase of clinical information systems should demand products in their practice settings that are Web enabled, use standard coding systems, and communicate with other computer systems via broadly accepted protocols.

Clinical Medicine↗
PubMed2003

The N400 in beginning readers.

In an event-related potentials study of brain-behavior relations during learning-to-read, girls in first grade viewed known words, unknown words, difficult words, and nonwords presented in list form. Participants were divided into low-ability and high-ability reading groups based on standardized test scores. During the 300- to 600-ms epoch, low-ability readers lacked a substantial N400 while high-ability readers evidenced a large, widely distributed negativity to all word types. During the 600- to 1,000-ms epoch, high-ability readers showed effects of repetition while low-ability readers did not. The findings indicate a less selective neurocognitive word-processing system in children as compared to adults and suggest that the N400 may serve as an oblique index of the automaticity of lower level processing.

Brain↗
PubMed1986

Prescription: office automation.

The mission statement of Minneapolis Children's Medical Center reads, in part, "Mindful of the unique characteristics of children, MCMC's missions is to provide a team of health care professionals attuned to the special needs of the total child, at all ages from prenatal through adolescent, in a uniquely designed facility." Therefore an "open" professional staff, rather than a medical staff, was established consisting of physicians, dentists, and other health professionals with advanced degrees at the master's level or above, including, but not limited to, psychologists, social workers, clinical nurse specialists, chaplains, audiologists, and speech pathologists. This professional staff has grown to 650 members, extremely large for a 122-bed hospital. The professional staff office needed help in managing the volume of information associated with this large staff. To meet that need, in addition to the needs of other hospital areas, MCMC's administration made the decision to purchase office automation equipment and established a committee of hospital-wide users, rather than managerial staff, to survey their own needs, select vendors, and make the final recommendation. The word-processing system selected now maintains 650 physician profiles, each with 44 variables. Whereas prior to automation 25 separate lists needed to be updated each time a professional staff member was either added or deleted, now only individual physician profiles need to be adjusted. Programs were then designed to automate the many reports that must be done. In this paper we propose to describe this selection process and relate how the system developed has streamlined and simplified the work of the professional staff office to enable it to increase its output by over 300% without adding staff.

Electronic Data Processing↗
PubMed1990

Managing journal references with JREF, an IBM-compatible program to simplify manuscript preparation.

JREF is a program which stores, manages and converts journal references. It is intended for the writer of articles and reviews, to simplify the task of keeping card indexes. Entries can be made from downloaded literature searches or from the keyboard. When writing, selections are made from the archival files, for conversion into the specific style of the chosen Journal. All files are ASCII text, accessible to most word processing programs. Once the accuracy of entries has been confirmed, these can be transformed into a perfectly punctuated bibliography.

Abstracting and Indexing↗
PubMed1999

[Importance of computer-based procedures. Planning and documentation in orthopedic surgery].

The demand for efficiency in OR management and increase in the necessity of surgical documentation require the use of software applications in hospitals. A client-server based OP-planning and documentation system has been in use in the department of orthopedic surgery in Giessen University since 1992 and is being continuously further developed. Aside from the lawful requirements, the demands of clinical doctors have been especially considered. The main functions are management of non medical patient data, scheduling and documentation of operations with coding of diagnoses and therapy, tissue banking, implant inventory, on call scheduling, storage of medical video images, clinical word processing and e-mail. With an integrated web-server, MedXS has the capabilities to offer functions accessible over any webbrowser (Netscape, Internet-Explorer) in the internet or intranet. Through the usage of this application clinical procedures could be more efficiently realized and better agreeing positions with the insurance companies could be reached.

Humans↗
PubMed1984

The personal computer as a clinical research and teaching tool.

The combination of the IBM Personal Computer and Lotus 1-2-3 software has made the personal computer of practical value to the surgeon. Within a month of spare time learning one can become competent in the use of the electronic spread sheet, data manipulation, basic statistics, and graph creation. Special functions, macros, and menus can be written into the program to tailor it to the investigator's individual needs. The software is self instructing, but the help and advice of a professional programmer is invaluable if a problem arises. Slide, table, and manuscript preparation time are minimized, particularly if a word processing package is added, and your secretary will love it!

Audiovisual Aids↗
PubMedDate not supplied

Generator program for computer-assisted instruction: MACGEN. A software tool for generating computer-assisted instructional texts.

This publication describes MACGEN, an interactive development tool to assist teachers to create, modify and extend case simulations, tutorial exercises and multiple-choice question tests designed for computer-aided instruction. The menu-driven software provides full authoring facilities for text files in MACAID format by means of interactive editing. Authors are prompted for items which they might want to change whereas all user-independent items are provided automatically. Optional default values and explanatory messages are available with every prompt. Errors are corrected automatically or commented upon. Thus the program eliminates the need to familiarize with a new language or details of the text file structure. The options for modification of existing text files include display, renumbering of frames and a line-oriented editor. The resulting text files can be interpreted by the MACAID driver without further changes. The text file is held as ASCII records and as such is also accessible with many standard word-processing systems if desired.

Computer-Assisted Instruction↗
PubMed1985

Microcomputer applications in pathology research.

In a study of over 700 cases of uveal melanoma on file in the Department of Pathology of Wills Eye Hospital, a low-cost microcomputer using commercially available software (without modification) was used to: word process and edit this manuscript, create a patient file storage and retrieval system including the ability to create subfiles, merge files, and interchange file types, plot data points in several different graphic formats, transcribe and store information from microscopic tissue sections containing intraocular melanomas, and solve complex equations including statistical analysis. The results showed that over 150 different ophthalmologists contributed specimens to this data base. The mean age of the patients studied was 57 years and the tumors were evenly distributed according to sex and laterality of the eye. This study illustrates the feasibility of using a low-cost microcomputer and commercially available software in the study of a large patient data base.

Computers↗
PubMed1986

An investigation of data entry methods with a personal computer.

The features of three methods of data entry were investigated and a trial of them was carried out using operators with differing amounts of keyboard experience. The first method was a simple system of character entry using a word processing package, and the second and third systems were written in a commercial data base language; one was designed to possess limited intelligence, the other moderate intelligence. The amount of time and computing expertise required to set up each method increased in parallel with its sophistication. The most sophisticated method offered theoretical advantages of reduced error rates and increased keying rates but these were not realized in practice. The limited intelligence method, in which data were entered into a screen image of the record form, was fastest overall and was most popular with all users. This method together with verification by dual keying will provide a convenient, rapid, and high fidelity method of data entry. The simplest method was found to be adequate for short forms but incurred high error rates with longer forms.

Computers↗
PubMed1989

MacSECPROT: two programs in BASIC to evaluate protein secondary structure.

Two interactive programs in BASIC are described, which provide useful tools to evaluate protein secondary structure. Output is given in two formats: (1) graphics are displayed on screen, which can be printed immediately, and (2) textfiles are saved to disk as permanent records and can be printed with a word-processing program. The programs are fast and easy to use and could be a valuable teaching aid in biochemical and molecular biology courses. Program lists are written in Microsoft BASIC for the Apple Macintosh, but can be adapted to other machines accepting graphic commands.

Microcomputers↗
PubMed1982

A short review of current laboratory microcomputer systems and practice.

In the last few years quite powerful complete computer systems have become available that fill many laboratory needs at low cost (US $3000-10,000). This development is based on the use of microcomputers, which now have capabilities that were previously associated with minicomputers. Due to the rapidly expanding use of microcomputers, a very large software base has been developed. As a result it is now feasible to use a microcomputer in the laboratory for signal averaging, controlling experiments, data analysis and reduction, printing and storage of results, plotting of graphs, curve fitting, statistics and word-processing. These applications of a microcomputer can make some other laboratory equipment unnecessary, thus providing substantial savings on items such as analog tape recorders, strip chart recorders, and stimulus generators.

Analog-Digital Conversion↗