SEARCH · Search PubMed
Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
We report for the first time in the Brazilian Amazon a typhoid fever patient with clinical and laboratorial resistance to chloramphenicol, drug of election for this disease in our region. The relapse was observed at the 7th day after the end of treatment and the patient was treated with ciprofloxacin.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Here, we report the case of fever of unknown origin (FUO) in a 77-year-old white man. The patient presented with a 3-week history of fever (between 38.5 and 39 degrees C) and general malaise. These symptoms had occurred about five to seven times during the past 30 years, and despite repeated hospitalizations, no diagnosis was made. Physical examination did not reveal any specific signs of infection nor did the patient fulfill the criteria for any rheumatic disease including vasculitides. Blood chemistry showed a greatly elevated C-reactive protein (CRP; 158.2 mg/l) and an erythrocyte sedimentation rate >100 mm, indicating an active inflammatory process, and leukocytes were significantly elevated (20,000/mul). Rheumatological parameters showed only nonspecific changes. Finally, a 2-[(18)F]-fluoro-2-deoxy-D: -glucose-positron emission tomography was performed, revealing a markedly enhanced glucose uptake in the ascending aorta and the cardiac valves, indicating vasculitis as the cause of FUO in this patient. Based on this finding, treatment was started with corticosteroids, and 2 days after the initiation of treatment, the patient had normal body temperature, and after 5 days, CRP values had returned to normal. After tapering and final complete removal of steroid treatment, the patient was still free of symptoms, hence no disease-modifying antirheumatic drug therapy was necessary.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The anti-epidemic compaign in Poland was in the hands of Chief Epidemic Commissariat. The Commissariat was organized on July of 1920y. as a special institution to fight against the acute infectious diseases. In the end of 1920y. it had 188 hospitals with 9,245 beds, with a reserve of 1,185 beds in the Red Cross, military hospitals and so on, it had a total of 12,915 beds. The tables of number 1 and 2 presented the number of the hospitals in Polish department, number of the beds, number of the patients and number of the hospital-days, number of the cases of the typhus, typhoid fever, relapsing fever, dysentery and the other diseases in the first half of 1920y. and in the second half of 1921y. As you see there were the most patients with the typhus. In 1922y. Epidemic Commissariat ordered of 116 hospitals with 10,785 beds. The table of the number 3 presented the number of the cases, deaths and the mortality of the typhus, relapsing fever, typhoid fever, dysentery, variola vera, cholera and the other diseases. In 1923y. Epidemic Commissariat had 112 hospitals with 11,000 beds. The table of number 4 confronted the number of the hospitals, number of the beds and its use in the hospitals ordered or inspected by Commissariat in 1922y. and in 1923y. there were 9 hospitals with 4,050 beds for the repatriates. In the half of 1923y. the repatriation was reduced and Epidemic Commissariat began to liquidate the part of the epidemic hospitals. The Commissariat had in the end of the year 4 hospitals in department of Kielce, 17 hospitals in the department of Bia3ystok, 19 hospitals in the department of Polesie, 11 hospitals in department of Nowogrodek, 14 hospitals in department of Wo3yn, 14 hospitals in department of Wino, 3 hospitals in department of Stanis3wow and 1 hospital with 100 beds in Tarnopol. Medical care of infectious diseases in the epidemic hospitals in 1919-1924 illustrated the table number 5. There were the numbers of the cases, deaths, hospitals, beds and patients. Generally the progress of epidemic hospitals was connected with the repatriation. In 1923y. the repatriation was finished also were reduced the new cases of infectious diseases. Part of the epidemic hospitals were closed and the others were taken by municipal authorities. The epidemic situation in Poland was better step by step and in 1924y. Epidemic Commissariat was liquidated.
Tick-borne diseases in the United States include Rocky Mountain spotted fever, Lyme disease, ehrlichiosis, tularemia, babesiosis, Colorado tick fever, and relapsing fever. It is important for family physicians to consider these illnesses when patients present with influenza-like symptoms. A petechial rash initially affecting the palms and soles of the feet is associated with Rocky Mountain spotted fever, whereas erythema migrans (annular macule with central clearing) is associated with Lyme disease. Various other rashes or skin lesions accompanied by fever and influenza-like illness also may signal the presence of a tick-borne disease. Early, accurate diagnosis allows treatment that may help prevent significant morbidity and possible mortality. Because 24 to 48 hours of attachment to the host are required for infection to occur, early removal can help prevent disease. Treatment with doxycycline or tetracycline is indicated for Rocky Mountain spotted fever, Lyme disease, ehrlichiosis, and relapsing fever. In patients with clinical findings suggestive of tick-borne disease, treatment should not be delayed for laboratory confirmation. If no symptoms follow exposure to tick bites, empiric treatment is not indicated. The same tick may harbor different infectious pathogens and transmit several with one bite. Advising patients about prevention of tick bites, especially in the summer months, may help prevent exposure to dangerous vector-borne diseases.
Explore the source record for details and available documents.
For several decades, borreliosis was synonymous with relapsing fever. Since the discovery of the agent of Lyme disease at the beginning of the 1980s, the term borreliosis now covers both relapsing fever and Lyme borreliosis. The relapsing fevers form a group of similar diseases that differ from each other, principally, in the different arthropod hosts used by the spirochete as a reservoir and vector. Relapsing fever may be transmitted either by lice (louse-borne relapsing fever) or by soft ticks of the genus Ornithodoros (tick-borne relapsing fever). For several years, reports on relapsing fever have been rare or nonexistent; however, louse-borne and tick-borne relapsing fever still occur. The disease is most probably confined to parts of Africa, Asia, and the Americas. For a deeper understanding of relapsing fever, recommended is a reading of the excellent monograph Borrelia by Oscar Felsenfeld.1 Lyme borreliosis is reported from those areas of the world where hard ticks of the genus Ixodes, which are the principal vectors of Lyme borreliosis in the Northern Hemisphere, occur. There is also speculation about the presence of Lyme borreliosis in the tropics.