SEARCH · Search PubMed

Results for “Program Appropriateness”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

SourceResearch connectionFrom yearThrough year

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 415 records · Page 23Linked to original sources

PubMed1993

Banking of environmental samples for short-term biochemical and chemical monitoring of organic contamination in coastal marine environments: the GICBEM experience (1986-1990). Groupe Interface Chimie Biologie des Ecosystèmes, Marins.

The GICBEM (Groupe Interface Chimie Biologie des Ecosystèmes Marins) program consists of an evaluation of the ecosystem health status in the Mediterranean Sea mainly based on chemical and biochemical approaches. Specific chemical contaminants (polycyclic aromatic hydrocarbons (PAH), polychlorobiphenyls (PCB), heavy metals) in waters, sediments, and related biotransformation indicators in target organisms (mussels, fish) have been selected for a complete survey of the coastal waters. In order to provide an appropriate sampling program for standardization for each sampling cruise, various aspects have been studied: (a) parameters for the choice of the sample sites; (b) ways of collection the samples (waters, sediments, marine organisms); and (c) preparation of the samples for a short term storage on board ship and for further analyses in the ground laboratory. Methods of preparation and storage of the samples are described and could be used to initiate an environmental banking program including both possible retrospective analyses of chemical pollutants and biochemical indicators. Moreover, the correlation between chemicals (PAH) and biochemical (mixed function oxygenase activities) parameters has been studied and this demonstrates the capability of the enzyme activities as reliable pollution biomarkers.

Animals↗

PubMed2004

Preparing psychiatry residents for the certification exam: a survey of residency and exam experiences.

OBJECTIVE: To determine which methods best prepare psychiatry residents for the certification exam, and ultimately for practice, to facilitate appropriate residency program curriculum changes. METHOD: We sent an anonymous survey to all final year (that is, PGY5) Canadian university-affiliated psychiatry residents, regarding frequency and diversity of observed interviews, form of feedback delivery, research and other training experiences, self-perception of preparedness and knowledge base, and management strategies for exam anxiety 6 months before and immediately after the certification exam. RESULTS: There was a 52% response rate. Residents from across Canada identified the following factors as enabling successful exam completion: regular mock orals supervised by Royal College examiners, clinical experience with exposure to a wide spectrum of pathologies, individual and group study time, and appropriate anxiety management. Preparation for the oral exam involving sample case vignettes with presentation and formulation skills training was considered to be essential but was identified as an area of educational and experiential weakness in some programs. CONCLUSIONS: To prepare psychiatry residents for successful completion of their certification exam, programs should incorporate regular mock orals observed by Royal College examiners throughout residency training (not just in PGY2 and PGY5). Programs should also incorporate training in case vignettes, training in oral exam skills, and teaching of anxiety-management strategies.

Adult↗

PubMed2003

The G8 Heart Health Projects Database: testing the compatibility of an Internet-based resource with health promotion planning processes.

This study examined the context and processes in which health promotion policy and program decisions are made to ensure that an Internet-based information system on heart health promotion programs provides appropriate information for decision makers' needs and is compatible with their decision-making processes. Five focus groups and six individual interviews were conducted with potential users of and contributors to the G8 Heart Health Projects Database. Results suggest that Internet-based systems such as this are seen as useful tools, but will only be used at certain critical points in program development and then, only when they meet several rigorous criteria. Systems must be completely credible and up-to-date, providing instant answers to complex questions about program design, implementation, and effectiveness, with adequate qualitative information for assessing contextual applicability. Participants also provided information about the conditions required if they were to submit project information to the system.

Benchmarking↗

PubMed2001

The place of guidelines and their means of dissemination.

INTRODUCTION: The literature shows that physicians do not change their patterns of practice quickly. With thousands of conflicting guidelines available, many disseminated by print, there has been little measurable impact of new guidelines on physician prescribing patterns. METHODS: A series of interventions designed to improve physician uptake of guidelines is described. Interventions evaluated in a series of trials include mail dissemination, small group continuing medical education sessions, academic detailing by both academic detailers and pharmaceutical detailers, and a whole community program known as the Program for Appropriate Anti-Infective Community Therapy. RESULTS: Only the whole community intervention had significant impact on physician prescribing patterns. The changes involved a significant reduction in anti-infective use and a significant change from the use of second- and third-line drugs to first-line drugs, as specified in the Ontario Anti-Infective Guidelines. CONCLUSIONS: Acceptable guidelines disseminated by a multidisciplinary community program can have a positive impact on physician prescribing patterns. To increase the acceptability of guidelines for whole community dissemination, a new innovation (Guideline Advisory Committee) that scores the quality of guidelines and selects the most objectively produced guideline is described.

Attitude of Health Personnel↗

PubMedDate not supplied

[Work and health conditions at a Venezuelan university].

OBJECTIVE: To identify occupational exposure to hazards among Venezuelan university (UN) workers. MATERIAL AND METHODS: A descriptive cross-sectional study was conducted in 1999 to assess occupational exposure among UN workers. Potentially hazardous events (PH) and their causes were identified. The study population consisted of 90 workers of both genders, working in any of the 24 areas classified as critical by university authorities. Work area and individual surveys were carried out. Data collected included demographic characteristics, occupational clinical history, hazardous occupational exposures, use of personal protection equipment, and knowledge about occupational risks and habits. Clinical-toxicological tests were performed. The major chemical, physical, biological, mechanical, and ergonomic PH were identified, as well as the degree of risk (DR) for each area. Central tendency and dispersion measures were calculated, in addition to association and statistical significance measures, as appropriate. RESULTS: A positive, significant correlation was found between time working in the university and the number of signs and symptoms reported by workers. No correlation was found between the number of signs and symptoms and age and gender. Symptoms were mainly non-specific. CONCLUSIONS: There are several potentially hazardous processes in the different occupational areas of the university. Recommendations are issued to implement prevention programs with appropriate recording of occupational accidents, and morbidity and mortality, to aid in the timely detection of occupational illnesses and accidents.

Adolescent↗

PubMed1999

Outpatient treatment of deep vein thrombosis: translating clinical trials into practice.

To develop a rational approach to outpatient management, we review the pharmacologic properties of low-molecular-weight heparins and their efficacy in clinical trials of deep vein thrombosis treatment. Low-molecular-weight heparins have better bioavailability and more predictable anticoagulant activity than standard heparin and thus can be administered without routine laboratory monitoring. Randomized trials comparing subcutaneous low-molecular-weight heparin administered primarily at home with inpatient intravenous standard heparin have established the safety and efficacy of outpatient treatment of selected patients. However, many patients were excluded from these studies. The benefits demonstrated in carefully controlled clinical trials of outpatient treatment of deep vein thrombosis required a complex multidisciplinary organization of medical care that is not readily achievable in routine practice. A structured protocol is necessary to ensure that patient care is optimal. The essential components of an outpatient program include appropriate patient selection, adequate patient education, daily follow-up during therapy with low-molecular-weight heparin, and easy access to health-care professionals.

Ambulatory Care↗

PubMedDate not supplied

[Efficiency of health care reform in Tajikistan].

The necessity is substantiated and the efficiency is evaluated in relation with the reform of healthcare that was undertaken after the beginning of the social-and-economic instability in the Republic of Tajikistan. Multiple purpose-oriented and national programs were appropriately elaborated in accordance with the world practice requirements. However, the understaffing and inadequate financing as well as a low standard of information support and of taken measures could bring about just minimal results.

Health Care Reform↗

PubMedDate not supplied

TV guides: exposure of hospitalized children to inappropriate programming.

OBJECTIVE: To determine if the policy recommendations of the American Academy of Pediatrics (AAP) regarding television viewing are heeded in an inpatient pediatric setting. SETTING: An inner-city academic medical center. PARTICIPANTS: Consecutive sample of 199 pediatric inpatients. METHODS: An investigator visited all pediatric inpatient rooms. Observations were made when the patient was present in the room, alert, and awake. The main outcome measure was exposure to inappropriate programming. In accordance with AAP guidelines, we used the established television rating system to code programs as appropriate versus inappropriate for children. We classified G- and PG-rated shows that centered on adult themes or that were not informational, educational, and nonviolent as inappropriate. We tested parental demographics, age of child, time of day, and presence of an adult in the room as possible predictors. RESULTS: Ninety-one percent of the patients had the television turned on. Of these, 53% were tuned to inappropriate programming. Exposure to inappropriate programming did not differ by parental ethnicity, language, or education. Exposure was highest for infants and toddlers as compared with children or adolescents (74% vs 40% vs 52%, P =.001); it did not vary by time of day. Exposure was higher when an adult was present in the room (58% vs 42%, P =.05); this effect was most pronounced for adolescents (68% vs 41%, P =.05). CONCLUSIONS: Despite AAP recommendations, hospitalized children are exposed to inappropriate programming, especially when parents are present in the room. Hospital stays may be a unique opportunity to educate parents about the AAP recommendations for television viewing by children.

Academic Medical Centers↗

PubMed1989

The metabolic evaluation of patients with recurrent nephrolithiasis: a review of comprehensive and simplified approaches.

The advent of percutaneous nephrostolithotomy and extracorporeal shock wave lithotripsy has definitely altered the way in which symptomatic renal calculi are approached. However, these new techniques should not affect the need for appropriate diagnostic evaluation and institution of medical treatment for the prevention of recurrent nephrolithiasis. A diagnostic evaluation should identify underlying physiological and environmental defects responsible for stone formation, as well as identify specific medical disorders that cause recurrent stone formation. With this information one then can construct an appropriate treatment program that will prevent the occurrence of additional calculi. Comprehensive metabolic protocols have evolved from tedious inpatient procedures to more convenient outpatient tests that can be performed in approximately 2 weeks. In addition, the advent of automated urinalysis packages has allowed many physicians access to reliable, sophisticated technology. Further dissemination of these simplified metabolic protocols will enable more accurate diagnosis of recurrent stone disease and, hopefully, permit the institution of appropriate medical therapy by a wider group of treating physicians.

Calcium↗

PubMed1996

Recurrent or new injury outcomes after return to work in chronic disabling spinal disorders. Tertiary prevention efficacy of functional restoration treatment.

STUDY DESIGN: A large prospective longitudinal cohort study (n = 1204) to identify prevalence of new or recurrent injury and risk factors in a rehabilitated chronic disabling spinal disorder patient group with matched control subjects. OBJECTIVES: To evaluate prevalence and risk factors for new or recurrent injury on a chronic disabling spinal disorder population. SUMMARY OF BACKGROUND DATA: The rate of symptom recurrence after acute low back pain, like the rate of initial back pain episodes, is extremely high (40-70%). However, although the incidence of recurrent back pain after chronic disabling spinal disorder represents a small subcomponent of these cases, there is a large socioeconomic impact. An individual attempting to return to work after a chronic disabling spinal disorder episode usually bears a stigma of "high risk" for recurrent injury and related work disability that may result in barriers to reemployment or work retention. Before the present research, no large scale studies had been conducted to evaluate whether recurrent spine injuries or new injuries to other musculoskeletal areas could be prevented by medical treatment. In addition, no studies had emerged to evaluate physical and psychologic risk factors of injury recurrence in this context to facilitate design of prevention programs. METHODS: The present study assessed the incidence of claimed recurrent spinal and new musculoskeletal injuries in a population of 1204 workers. A subgroup of 5.3% (n = 64) of treated patients with a new injury claim in the ensuing 12 months was matched for gender, age, race, length of disability, workers' compensation venue, previous surgery, and litigation status to an identically sized control group who did not report new or recurrent injuries. Demographic, physical, and psychologic measures were obtained prospectively on all patients, before and after treatment, to be analyzed as risk factors. RESULTS: During the year after treatment, 1.3% (n = 16) of patients reported another injury to the same spinal area, with only a 0.9% (n = 11) recurrent disability rate. A new injury to a different musculoskeletal area was reported by 4.0% (n = 48) of patients. Only 3.4% of the whole cohort, or 64.1% (n = 41) of the sample reporting reinjuries after returning to work, experienced lost work time (i.e., disability) after the reinjury. Only a modest predictive association was found between risk for new or recurrent injury and two self-report indices. CONCLUSIONS: The present study suggests that even a sample of the most severe chronic disabling spinal disorder workers' compensation patients who complete a tertiary functional restoration program are at relatively low risk for either a recurrent spinal disorder or new musculoskeletal injury claim (with or without disability). No major physical or psychologic risk factors for recurrent injury could be identified in this large cohort. These findings argue powerfully against employer bias in not rehiring employees with previous chronic disabling spinal disorder or discriminating in pre- or reemployment on the basis of putative reinjury risk factors after an appropriate rehabilitation program. Literature review documents a surprising paucity of quality studies examining variables predictive of this important socioeconomic outcome variable.

Adult↗

PubMed2004

Constants and variables in immunohistochemistry.

Many efforts have been made to develop reliable methods for the quantification of immunohistochemical reaction products. Most of the corresponding studies have dealt with problems related to the development of adequate hardware and software, while fewer investigations have focused on variables of histotechnical or immunohistochemical methods. The present paper summarizes findings and experience obtained over many years in this latter field, and a total of 14 corresponding parameters were considered. The studies were performed with methods well established in the author's laboratory; namely immunohistochemistry for various pancreatic hormones and chromogranin A applying the peroxidase anti-peroxidase method on serial semithin sections from the mammalian endocrine pancreas. Optical densities of immunoreactivities were determined using an appropriate measuring program by the interactive image analysis system IBAS. All parameters investigated were found to influence densities of immunoreactivities, and those with major significance were: 1) the thickness of histologic sections; 2) the dilution range of the antisera used as first layers; 3) the type or composition of the buffers used for dilution of the antisera and of the chromogen di-aminobenzidine or as the rinsing solution. All these variables could be standardized in appropriate ways. It was not possible, however, to prevent batch-to-batch (inter-assay) variations. Finally, the results of the present investigations served to increase the efficiency of immunohistochemical staining by the applied methods.

Animals↗

PubMed2000

MR imaging and cardiac pacemakers: in-vitro evaluation and in-vivo studies in 51 patients at 0.5 T.

PURPOSE: To evaluate the safety and feasibility of magnetic resonance (MR) imaging at 0.5 T in patients with implanted cardiac pacemakers. MATERIALS AND METHODS: Twenty-one models of pacemakers and 44 pacemaker electrodes were exposed to in vitro MR imaging with continuous registration of pacemaker output and temperature at the lead tip. Prior to MR imaging examination, pacemakers were programmed to an asynchronous mode (A00, V00, or D00). Pacemakers were examined before and after MR imaging. Forty-four patients with implanted pacemakers underwent 51 MR imaging examinations under cardiologic surveillance, continuous electrocardiography, pulse oximetry, and capnographic monitoring. RESULTS: MR imaging was safely performed in all patients. None of the pacemakers displayed a pacing dysfunction at MR imaging. No changes occurred in the programmed parameters in any device tested in vivo or in vitro. Maximum increases in the temperature at the lead tips were 8.90 degrees C at a specific absorption rate (SAR) of 0.6 W/kg and 23.50 degrees C under a worst-case radio-frequency (RF) heating condition with an SAR of 1.3 W/kg. CONCLUSION: MR imaging at 0.5 T can be safely performed in patients with implanted pacemakers in carefully selected clinical circumstances when appropriate strategies (programming to an asynchronous mode, adequate monitoring techniques, limited RF exposure) are used.

Capnography↗

PubMedDate not supplied

Proper handwashing promotes wellness in child care.

INTRODUCTION: The purpose was to determine the effectiveness of an instructional program on handwashing. The hypothesis stated that an instructional program on germs and handwashing in child care could significantly reduce the spread of infectious diseases in the test center. METHOD: A longitudinal study was conducted in a field setting with a test group and a control group of 3- to 5-year-old children and their teachers in two similar child care settings. For 21 weeks illnesses and symptoms of infectious diseases were assessed with a health assessment checklist. The test group received a developmentally appropriate instructional program on germs and handwashing. The teachers in the test group attended workshops on infectious diseases and handwashing. The control group maintained their usual handwashing procedures. RESULT: At weeks 1 through 11 benchmark data were collected. At weeks 12 through 21, peak cold and flu season, the test group had significantly fewer colds than the control group (chi-squared analysis, 4.338, 1 df, p < .05); thus the hypothesis was confirmed. DISCUSSION: Handwashing has been recognized as one way to manage the spread of infectious diseases in child care centers. Handwashing helped to reduce colds at the test center where frequent and proper handwashing practices were incorporated into the curriculum through an intervention program.

Child Day Care Centers↗

PubMed1984

A randomized trial of exercise training in patients with coronary heart disease.

In order to determine whether or not regular exercise could alter myocardial perfusion or function, we randomized 146 male volunteers with stable coronary heart disease to either a supervised exercise program (n = 72) or to a usual care program (n = 74). Subjects underwent exercise tests initially and one year later. Significant differences between the two groups included improved aerobic capacity, thallium ischemia scores, and ventricular function in the exercise intervention group. It was not possible to classify the conditions of patients as to the likelihood of improvement or deterioration. This study demonstrated changes in myocardial perfusion and function in a select group of middle-aged men with coronary heart disease who underwent a medically appropriate exercise program lasting one year, but these changes were relatively modest.

Adult↗

PubMedDate not supplied

Enabling the nation's schools to help prevent heart disease, stroke, cancer, COPD, diabetes, and other serious health problems.

In the United States, more than 53 million young people attend nearly 120,000 schools, usually for 13 of their most formative years. Modern school health programs--if appropriately designed and implemented--could become one of the most efficient means the nation might employ to reduce the establishment of four main chronic disease risks: tobacco use, unhealthy eating patterns, inadequate physical activity, and obesity. The U.S. Centers for Disease Control and Prevention and its partners have developed four integrated strategies to help the nation's schools reduce these risks. Participating national, state, and local agencies (1) monitor critical health risks among students, and monitor school policies and programs to reduce those risks; (2) synthesize and apply research to identify, and to provide information about, effective school policies and programs; (3) enable state, large city, and national education and health agencies to jointly help local schools implement effective policies and programs; and (4) evaluate implemented policies and programs to iteratively assess and improve their effectiveness.

Chronic Disease↗

PubMed1985

Evaluation of the Bolie model describing blood glucose response for the application to continuous subcutaneous insulin infusion.

In an attempt to develop an appropriate infusion program in a continuous subcutaneous insulin infusion system, a conventional pharmacodynamic model (the Bolie model) for describing the relationship between blood glucose and serum insulin levels was evaluated, using a depancreatized dog preparation. The Bolie model was found useful in estimating the basal insulin infusion rate. However, the model could not predict the serum insulin concentration-time profile required to maintain the postprandial blood glucose levels within a physiological range. It will be necessary to develop a more appropriate model for determining the prandial subcutaneous insulin infusion rates in the continuous subcutaneous insulin infusion system.

Animals↗

PubMed2001

A modified biofeedback program for children with detrusor-sphincter dyssynergia: 5-year experience.

PURPOSE: We reviewed our 5-year experience with a modified 4 to 6-session biofeedback program combining noninvasive urodynamic approaches with various psychological techniques, including externalizing the voiding problem, empowerment and praise, to treat children with detrusor-sphincter dyssynergia. MATERIALS AND METHODS: Biofeedback was performed with a urodynamics processor that enables simultaneous recording of urine flow and electromyography, and visual display of flow/electromyography activity. Initially normal and abnormal voiding were explained in a unique way and the children observed relaxation and contraction of the pelvic floor muscles while visualizing the electromyography monitor. The bladders were filled naturally and surface electrodes were placed. Psychological strategies were used to engage and motivate the children to achieve maximal cooperation. The children voided while attempting relaxation and post-void residual urine volume was measured by bladder scan. Special and specific praise was provided for progress and increasing self-esteem. Patients returned monthly to review these concepts and practice voiding. RESULTS: Of 87 children 77 completed the program, including 7 boys and 70 girls 3 to 17 years old (mean age 7.8) who required an average of 4.7 sessions (median 4). Results were achieved within 6 sessions in 82% of cases. Of the 77 children 59 (76%) had recurrent urinary tract infections, 38 (49%) had associated bladder instability, 19 (24%) had vesicoureteral reflux and 44 (58%) had constipation. Subjectively 47 patients (61%) reported pronounced improvement in urinary symptoms, while another 24 (32%) reported moderate improvement after biofeedback training. Objectively 47 children (61%) had normal flow with minimal electromyography activity during voiding and a normal post-void residual urine of less than 20% voided volume (p <0.002). In 28 cases (36%) flow studies improved (p <0.03) but post-void residual urine remained elevated. Vesicoureteral reflux resolved in 9 cases after biofeedback training. This approach was equally successful in children in all age groups. Those with more than a 2-year history of symptoms, poor bladder emptying and severe constipation had only moderate improvement. CONCLUSIONS: The modified biofeedback program including appropriate explanations and psychological approaches appeared effective for treating 92% of children with detrusor-sphincter dyssynergia. It is less invasive and requires less time than traditional methods, and patients are more compliant with treatment.

Adolescent↗

PubMed2006

Proceedings of the 4th Georg Rajka International Symposium on Atopic Dermatitis, Arcachon, France, September 15-17, 2005.

The 4th Georg Rajka International Symposium on Atopic Dermatitis presented a comprehensive view of our current understanding and management of atopic dermatitis (AD). These proceedings highlight contributions related to the history of AD doctrines; genetic and epigenetic background; epidemiology; maturation of the immune system; infection and innate-adaptive immunity; epidermal inflammation, including neurogenic inflammation and pruritus; animal models; skin barrier; evidence-based therapy and education programs; prognostic and severity markers; and allergy testing. Several studies in animal models and human subjects point to impaired skin barrier function as a primary defect that facilitates the effect of environmental factors and immune dysregulation found in AD. The new frontier in AD therapy should, in the near future, reflect our better understanding of the skin barrier. The influence of environmental factors on the skin and other epithelial barriers in the perinatal period needs to be better understood to implement appropriate prevention programs.

Animals↗