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Results for “Polydipsia”

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At least 415 records · Page 23Linked to original sources
PubMed1978

Polydipsia, polyuria, and hypertension associated with renin-secreting Wilms tumor.

A 16-month-old black male infant had unusual thirst, polyuria, hyponatremia, and hypertension. His polyuria was unresponsive to vasopressin therapy, and his high blood pressure was not effectively controlled by antihypertensive drugs. Radiographic examinations revealed an occult Wilms tumor in the right kidney. After removal of the tumor, the signs and symptoms were relieved. The tumor had a renin activity about 280 times that of the adjacent renal cortex, and many intracytoplasmic secretory granules were found on electron microscopy. The pathogenesis of these clinical manifestations appears to be mediated through the physiologic pathways of renin-angiotensin II and renin-aldosterone.

Humans↗
PubMedDate not supplied

Effects of d-amphetamine on temporal distributions of schedule-induced polydipsia.

Food-deprived rats were divided into four groups according to the equal interval and time durations of a multiple fixed-interval, fixed-time schedule (15, 30, 60, and 120 s). Fixed-time components were signaled by a tone and lever withdrawal. d-Amphetamine (0.25-4.0 mg/kg) produced similar dose-dependent reductions in the drinking and licking induced by fixed-interval and fixed-time schedules. These dose-dependent decrements were a function of the interfood interval length. More licks occurred early in the interfood intervals with doses of d-amphetamine. Dose-dependent shifts to the left were observed in the distribution of licking, and there were dose-dependent decreases in the quarter-life, which were a function of fixed-interval and fixed-time lengths. The maximum lick rate within interfood intervals occurred at about the same absolute time in schedules up to 60 s; therefore, the effects of d-amphetamine were not mediated by its effects on temporal discrimination.

Analysis of Variance↗
PubMed1985

Psychogenic polydipsia in a patient with anorexia nervosa.

This report describes the first reported case of compulsive water drinking (CWD) in an adolescent with anorexia nervosa (AN). The CWD appears to be a bulimic behavior with potentially serious medical complications. The concurrence of AN and CWD suggests possible hypothalamic dysfunction of food and water regulation.

Adolescent↗
PubMed1975

Effects of desalivation on schedule-induced polydipsia in the rat.

The development and magnitude of schedule-induced polydipisa (SIP) were examined in desalivate and control rats in two experiments. In Experiment 1 animals were placed on a noncontingent fixed time (FT) 60-sec schedule for 24 days. Results indicate speeded development but asymptotically lower levels of SIP in desalivate rats compared to controls. Home cage consumption, however, was elevated in desalivate rats. In Experiment 2 schedule length, pellet size, and the percentage of body weight were manipulated. Desalivate rats consumed less fluid during each schedule condition relative to controls, but the pattern of results across schedules was similar to controls. It was concluded that (a) desalivation attenuates SIP; (b) SIP is a learned phenomenon; (c) dry mouth theories of SIP appear inadequate; and (d) the developmental aspect of the SIP phenomenon deserves additional research attention.

Animals↗