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Reappearance of Aedes aegypti (Diptera: Culicidae) in Lima, Peru.

We report here the reappearance of Aedes aegypti in the Rimac district, and summarize the history of this mosquito species in Peru since its first detection in 1852. On March 17 2000 were found Ae. aegypti and Culex quinquefasciatus in Mariscal Castilla town, Flor de Amancaes, San Juan de Amancaes, El Altillo and Santa Rosa in the Rimac district, Lima Province.

Aedes↗

Planorbidae, lymnaeidae and physidae of Peru (Mollusca: Basommatophora).

In the course of several trips to Peru I had the opportunity of collecting topotypic specimens of Biomphalaria andecola (Orbigny, 1835), B. helophila (Orbigny, 1835), B. pucaraensis (Preston, 1909), Drepanotrema limayanum (Lesson, 1830), D. kermatoides (Orbigny, 1835), and Lymnaea viatrix Orbigny, 1835, besides B. tenagophila (Orbigny, 1835), Helisoma trivolvis (Say, 1817), H. duryi (Wetherby, 1879), Physa acuta Draparnaud, 1801, and seemingly P. peruviana Gray, 1828. B. pucaraensis is considered a junior synonym of B. peregrina (Orbigny, 1835).

Animals↗

Techniques of DNA-studies on prehispanic ectoparasites (Pulex sp., Pulicidae, Siphonaptera) from Animal mummies of the Chiribaya culture, southern Peru.

During a paleoparasitological survey of several animal mummies (Cavia aperea f. porcellus and Canis familiaris) from Chiribaya Baja, an archaeological site in Southern Peru, an unexpected find was made. In the well preserved fur, large numbers of mummified fleas (Pulex simulans/irritans) that parasitized the animals during life were encountered. Due to the relative recent event of the host mummification and the outstanding preservation of the fleas, an attempt for the retrieval of DNA was made. A DNA extraction and sequencing protocol for archaeological ectoparasitic remains has been established, taking additional studies for tissue and protein preservation into account. Tissue preservation was assessed with transmission electron microscopy and the protein preservation was tested through the racemisation ratios of aspartic acid. Regions of the 28S rDNA gene were successfully amplified and sequenced. Further research perspectives are outlined.

Animals↗

Louse infestation of the Chiribaya culture, southern Peru: variation in prevalence by age and sex.

In order to improve the interpretive potential of archaeoparasitology, it is important to demonstrate that the epidemiology of ancient parasites is comparable to that of modern parasites. Once this is demonstrated, then we can be secure that the evidence of ancient parasitism truly reflects the pathoecology of parasitic disease. Presented here is an analysis of the paleoepidemiology of Pediculus humanus infestation from 146 mummies from the Chiribaya culture 1000-1250 AD of Southern Peru. The study demonstrates the modern parasitological axiom that 10% of the population harbors 70% of the parasites holds true for ancient louse infestation. This is the first demonstration of the paleoepidemiology of prehistoric lice infestation.

Age Distribution↗

A profile of sexually active male adolescent high school students in Lima, Peru.

To document knowledge and attitudes regarding sexuality and sexual practices of male adolescent high school students in Lima, Peru, a self-administered, anonymous survey was completed by 991 male adolescents aged 12-19 as part of a School-Based Sex Education Intervention model. Questions concerned sociodemographic information; family characteristics; personal activities; knowledge and attitudes regarding sexuality; sexual experience; and contraceptive use. Knowledge related to sexuality was limited. Males tended to mainly discuss sexuality with their male peers (49.8%). Attitudes towards sexual activity and condom use were largely positive, although some males expressed ambivalent feelings towards the latter. Of the sample, 43% had ever had sex; age at first sexual intercourse was 13 years. While 88% of the sample would use condoms, 74% also gave reasons for not using them. Sexual activity was related to age, ever having repeated a grade, living with only one parent or in a mixed family, activities such as going to parties, use of alcohol, tobacco, and drugs, and viewing pornographic videos or magazines. Many male adolescents were at risk of causing an unintended pregnancy or acquiring an STD.

Adolescent↗

[Health sector reform and pharmaceutical policy in Peru].

This article analyzes the Shared Pharmaceutical Management Program (PACFARM) and its relationship to pharmaceutical policy in Peru within the scope of health sector reform. Implementation of various programs for essential medicines has involved an on-going effort towards improving the supply of essential drugs to the community. However, the corresponding legal framework includes random and disconnected regulations which hinder the feasibility of a consistent national drug policy. PACFARM is a decentralized system for the provision of essential medicines on a care-level basis, self-supported by revolving funds. While expanded coverage and decreased economic barriers to access to essential medicines provided the basis for a pharmaceutical policy and traits of supply management efficiency kept pace with administrative modernization as part of the reform, other aspects hindered the program's implementation and limited its effects, including deregulation and the very processes of change in the sector. The study's methodology included qualitative and quantitative techniques, prioritizing an analysis of the program's implementation.

Drug Utilization↗

[Knowledge, attitudes, and practices concerning Chagas disease in schoolchildren from an endemic area in Peru].

This study analyzes knowledge, attitudes, and practices concerning Chagas disease among 241 primary schoolchildren in "La Tinguiña", Ica, Peru (December 2000 - January 2001). Less than 1% of those interviewed knew that triatomines transmit Chagas disease, while nearly a quarter recognized the illness based on the appearance of "lumps" on the skin; 35.27% knew that vector infestation is controlled using insecticides; 26.56% recognized the adult stage of the vector, and 21.16% the nymphal instar; 14.11% knew triatomines or "kissing bugs" by the name "chirimacha"; 82.57% would accept an entomological survey, 66.80% would submit to a serological study, and 63.90% would participate in a triatomine search. The study shows that the population, despite having very limited knowledge on the disease and its vectors, shows interest in collaborating. Therefore, it is recommended that Chagas disease surveillance and control include educational programs and community participation.

Adolescent↗

Cervical cancer in Iquitos, Peru: local realities to guide prevention planning.

Cervical cancer is a major public health problem in Latin America, and in much of the underdeveloped world. This issue has not historically been addressed as a health priority, but in recent years is receiving increased attention and funding. This ethnographic study on the experience of cervical cancer was conducted in Iquitos, Peru, between August 1998 and May 1999. Research methodologies included: (1) observation and household interviews to obtain background knowledge about the region, medical systems, and local cultural understanding of illness; (2) cancer experience interviews; and (3) case studies of women in various stages of cervical cancer or diagnosis. Findings are presented related to local knowledge and experience of Pap smears and cervical cancer and the ineffectiveness of a recently initiated cervical cancer screening program. The findings guide recommendations for interventions in the region in relation to: (1) needed changes in health education, (2) screening frequency and age, (3) sites for screening and treatment, (4) type and availability of treatment, (5) payment issues, (6) documentation of care, and (7) the potential of herbal remedies.

Adult↗

[Sexual relations and the perception of risk of acquiring STD/AIDS among young adult men in Lima, Peru].

The purpose of this study was to identify men's co-responsibility in the negotiation process of dual protection, according gender, in their first and most recent sexual relationships, and their perception of the risk of STD/AIDS. We surveyed 750 males from 19 to 29 years of age in 2,250 randomly selected households in metropolitan Lima, Peru. The majority mentioned condoms as a contraceptive technique (95%). Their first sexual relationships occurred with a female friend, with a stable partner, or with a known woman. Almost half used some type of protection, principally condoms in order to avoid pregnancy, but their consistent and correct use was low. For 39.5%, the most recent sexual relationship was with a stable partner, a female friend or "known" woman, a wife, or a female co-resident. Dialogue about protection increased between the first and the most recent sexual relationships. The perception of risk of acquiring STD/AIDS was low, and they tended to use protection only with an "unknown partner".

Acquired Immunodeficiency Syndrome↗

[Attitudes of graduate nursing students towards mental disorders in Brazil, Chile and Peru].

This study aimed to draw a profile of nursing graduate students' attitudes towards mental disorders in three different cultures: Brazil, Chile and Peru. The opinion scale for mental disorders was applied. The results showed statistically significant differences (5%) in terms of authoritarianism, mental hygiene ideology, serial restriction and minority vision, which were favorable to Brazilian students. As to the factor interpersonal etiology, the results were favorable to Peruvians, while the results for etiology of mental strain were favorable to Chileans. There was no statistical evidence to confirm any difference in terms of benevolence. These results reveal that Brazilian students present more positive attitudes towards mental disorders, as they showed to be less authoritarian, restrictive and discriminative than the Chilean and Peruvian students. Therefore, they are more likely to develop a more therapeutic behavior towards people with mental disorders.

Adult↗

[Intrafamily violence during adolescence in the city Puno--Peru].

This epidemiological case-control study aimed to describe the epidemiological profile of intrafamily violence against pregnant and non pregnant adolescents. The study was carried out at the outpatient clinic for central care to adolescents of the Regional Hospital Manuel Nuñez Butrón and at secondary schools in the city of Puno--Peru. The results were obtained by means of statistical analysis, verifying statistically significant differences for the occurrence of physical violence (p = 0.008) and sexual-rape violence (p = 0.01). The majority of the adolescents were victims of different types of aggression, executed either by members of the family (intrafamily) or by individuals outside the family (extrafamily). The most frequent causes associated to this aggression were disobedience, late arrival at home, having friends/boyfriends and doing domestic chores slowly.

Adolescent↗

[The trail of AIDS in Peru].

This historical study of the Aids epidemic in Peru between 1983 and 2000 focuses on legal responses and on medical studies and intervention, especially during the early 1980s, a decade characterized by serious economic crisis and terrorist violence. As elsewhere around the world, the appearance of Aids intensified interactions between scientists, public health specialists, journalists, politicians, and patients, with major influence on culture as well as on public health responses to the disease. In addition to retelling an important story, the study demonstrates the validity and usefulness of the historical perspective, which affords a better understanding of recent events in health and in society overall.

Acquired Immunodeficiency Syndrome↗

[Peru's experience with a national blood banking program].

This paper describes Peru's experiences with its National Blood Banking Program. Until the mid-1990s, the country faced a host of problems, including the lack of a legal framework to regulate blood banks, a high maternal mortality rate due to a shortage of blood, virtually no voluntary donations, a high risk of infection from transfusions, the use of only whole blood for transfusion, serious disorganization in the blood banks, deficiencies in blood bank supervision and control, no training programs, indifference on the part of health officials, frequent selling of blood, and limited community awareness. Subsequently, a strategic plan was prepared that made it possible to solve many of those problems. Legal instruments were prepared; the rate of voluntary donations rose from 0% to 19.5%; the safety of the blood was improved through compulsory screening of all donated blood units for seven markers of infectious diseases, as well as by placing a national seal of quality on all screened units. The availability of blood doubled, thus meeting 70% of the need; sales of blood decreased; and the use of blood components was improved, with 80% of the blood being fractionated. In addition, supervisory control of 100% of the blood banks in the country was achieved, a national registry was established, the cost-benefit relationship for blood units was improved through centralized screening, internal and external quality control was made mandatory, and pro-donation campaigns led to commitments from civil society. While important, all these achievements represent just a first step. This is especially true given that developing the National Blood Banking Program required the participation of outside organizations, such as the Pan American Health Organization, whose support, together with the experience provided by other countries, was key. The Program is facing a number of new challenges, and the progress that has been achieved could be threatened if current activities stagnate or if officials become complacent.

Blood Banks↗

[Cataract blindness in people 50 years old or older in a semirural area of northern Peru].

OBJECTIVE: To determine the prevalence of blindness and of cataract blindness in persons 50 years of age or older in Piura and Tumbes, which are two departments in northern Peru, and to describe the coverage and quality of cataract surgery services in that area, and the barriers that prevent access to those services. METHODS: Systematic sampling of persons 50 years old or older was done in Piura and Tumbes between August 2002 and March 2003, with 80 clusters of 60 people each being selected. Of the 4 800 persons chosen, 4,782 of them were examined, using a survey instrument that gathered general information on each person, the results of the visual acuity test and the lens examination, and information on cataract surgery or why that surgery had not been done. Visual acuity (VA) testing was done with a Snellen optotype with the letter "E," with sizes of 20/60 and 20/200 at distances of 6 m and 3 m, respectively, with the person using the visual correction (glasses) available. When the VA was less than 20/60 in one of the eyes, vision was tested with pinhole glasses. RESULTS: The prevalence of bilateral blindness (VA < 20/400) due to cataract, adjusted by age and sex, was 2.1% (95% confidence interval (CI): 1.7% to 2.6%). Among the 193 persons with bilateral blindness due to any cause, cataract was the cause in 104 of them (53.9%). The prevalence of blindness due to cataract or other causes increased with age and was higher in women than in men. Only 25% of the persons studied who needed cataract surgery had had that done. The prevalence of bilateral VA less than 20/200 due to unoperated cataract was 6.3% (95% CI: 5.3% to 7.3%); only 12% of the persons with that level of visual deficiency had had cataract surgery. The VA of 26% of the eyes operated on for cataract was lower than 20/200. The reasons given by persons who needed cataract surgery but who had not had it included not being able to pay for the operation (28%), lack of knowledge concerning cataracts (25%), fear of the operation (23%), and fear of completely losing their sight (17%). CONCLUSIONS: Most of the cases of blindness and of serious deficiency in visual acuity in persons 50 years old or older in Piura and Tumbes are due to uncorrected refractive defects, especially cataracts. The high prevalence of bilateral blindness due to cataracts (2.1%) could be reduced with measures that facilitate access to appropriate treatment.

Aged↗

[Predictive factors for noncompliance with tuberculosis treatment in an endemic region of Peru].

OBJECTIVE: To identify factors that predict noncompliance with tuberculosis treatment in the province of Ica, Peru. METHODS: Between 1998 and 2000 a case-control study (1:1 ratio) was conducted in the province of Ica, with 55 cases (persons who dropped out of treatment) being identified. The factors evaluated were chosen from Lalonde's model of the field of health. The respective odds ratios were calculated by means of univariate analysis and multivariate analysis. RESULTS: The following factors were identified as being predictive of noncompliance with tuberculosis treatment: thinking that the information that health workers provided on treatment was insufficient (odds ratio (OR) = 4.20; 95% confidence interval (95% CI), 1.77-10.02), thinking that the office hours for receiving treatment were inadequate (OR = 9.95; 95% CI, 1.97-50.21), and consuming illegal drugs (OR = 7.15; 95% CI, 1.69-30.23). CONCLUSIONS: To improve compliance with tuberculosis treatment, it is necessary to provide patients with personalized information on the disease and its treatment, and to offer them flexible, appropriate times to receive treatment. Drug consumption is the most serious risk factor for noncompliance, and identifying and following up with drug users is crucial.

Antitubercular Agents↗

Atovaquone and proguani hydrochloride compared with chloroquine or pyrimethamine/sulfodaxine for treatment of acute Plasmodium falciparum malaria in Peru.

The efficacy and safety of a fixed-dose combination of atovaquone and proguanil hydrochloride (Malarone) were compared with chloroquine or pyrimethamine/sulfadoxine in patients with acute falciparum malaria in northern Peru. Patients were initially randomized to receive 1,000 mg atovaquone and 400 mg proguanil hydrochloride daily for 3 days (n=15) or 1,500 mg chloroquine (base) over a 3 day period (n=14) (phase 1). The cure rate with chloroquine was lower than expected and patients were subsequently randomized to receive a single dose of 75 mg pyrimethamine and 1,500 mg sulfadoxine (n=9) or atovaquone/proguanil as before (n=5) (phase 2). In phase 1, atovaquone/proguanil was significantly more effective than chloroquine (cure rate 100% [14/14] vs. 8% [1/13], P<0.0001). In phase 2, atovaquone/proguanil and pyrimethamine/sulfadoxine were both highly effective (cure rates 100% [5/5] and 100% [7/7]). There were no significant differences between treatment groups in parasite or fever clearance times. Adverse events were typical of malarial symptoms and did not differ significantly between groups. Overall efficacy of atovaquone/proguanil was 100% for treatment of acute falciparum malaria in a region with a high prevalence of chloroquine resistance.

Adolescent↗