Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “MONKEY DISEASES”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 415 records · Page 23Linked to original sources
PubMed1983

Pulmonary cryptococcosis: radiologic-pathologic correlates of its three forms.

To better understand the radiographic appearance of pulmonary cryptococcosis, 23 human cases and three cases in zoo animals were studied in which both radiographic and pathologic material was available for correlation. Radiographs in 44 additional cases were studied in which documentation was microbiologic but not pathologic. Three forms of pulmonary cryptococcal disease are recognized: (1) air-space collections of fungus with minimal or no inflammatory reaction, causing well defined masses both radiographically and pathologically, as documented by five cases in this series; (2)granulomatous infection, demonstrated here by 21 cases, producing segmental consolidation, poorly defined masses, or "infiltrative masses," often accompanied by lymph node enlargement; and (3) airway colonization without parenchymal infiltration resulting in no significant or specific radiographic findings and no specific pathology. The most specific and distinctive radiographic finding in pulmonary cryptococcosis is the "infiltrative mass," which resembles a mass in one view and an infiltrate in the 90 degree different view. A review of cryptococcosis shows the value of pathologic correlation of the form of the disease in understanding the radiographic abnormalities.

Adult↗
PubMed2004

Legg-Calvé-Perthes disease in a rhesus macaque (Macaca mulatta).

A juvenile rhesus macaque presented with atrophy of the musculature of its left leg. Physical examination localized the problem to the coxofemoral joint. Radiography revealed changes consistent with Legg-Calvé-Perthes (LCP) disease. Femoral head ostectomy was performed, and the femoral head was submitted for histologic examination, results of which confirmed a diagnosis of LCP.

Animals↗
PubMed2006

Detection of systemic amyloidosis in the pig-tailed macaque (Macaca nemestrina).

Secondary amyloidosis is a progressive systemic disease for which there is no reliable diagnostic assay, preventive measure, or treatment. In an attempt to elucidate an antemortem diagnosis, 30 female pig-tailed macaques (Macaca nemestrina) at the Washington National Primate Research Center were surveyed for amyloidosis. Amyloid was demonstrated histologically in 47% (14 of 30) of the animals. The distribution and severity of amyloid deposition was variable. Affected animals had a mean age (+/-1 standard deviation) of 13.2 +/- 4.9 y, which was significantly greater than the mean age of unaffected animals (9.3 +/- 4.1) y. Twelve tests were evaluated for detection of amyloidosis; the diagnostic value of each was determined through comparison of histologically positive and histologically negative animals. Diagnostic tests evaluated were endoscopic examination and biopsy of the stomach and colon, abdominal ultrasonography, hepatic radiology, serum amyloid A (SAA), endothelin 1, alpha-fetal protein, aspartate aminotransferase (AST), alanine aminotransferase, gamma-glutamyltransferase (GGT), alkaline phosphatase, cholesterol, blood urea nitrogen, total bilirubin, C-reactive proteins, and erythrocyte sedimentation rate. Amyloidotic animals demonstrated a distinctive serologic profile: elevated SAA, GGT, and AST in combination with decreased total protein and albumin. Radiology demonstrated hepatomegaly in animals with hepatic amyloid deposition. In the absence of known infection or trauma, an amyloidotic serologic profile and radiologic hepatomegaly are consistent with systemic amyloidosis in M. nemestrina.

Age Factors↗
PubMed1991

An epizootic of histoplasmosis duboisii (African histoplasmosis) in an American baboon colony.

Histoplasmosis duboisii, a chronic granulomatous disease caused by Histoplasma capsulatum var. duboisii, was diagnosed in 21 baboons at a large primate colony in San Antonio, Texas. Diagnosis was based on finding 8 to 15 microns-diameter yeast cells in histologic sections. Therapy with drugs was unsuccessful. Surgical removal of lesions was the primary treatment. Epidemiologic data suggest the incubation period to be at least 9 months. The most likely route of infection was oral and happened during grooming by the baboons.

Animals↗
PubMed1989

Focal ulcerative ileocolitis with terminal thrombocytopenic purpura in juvenile cotton top tamarins (Saguinus oedipus).

A newly recognized syndrome characterized by an acute focal ulcerative ileocolitis, anemia and thrombocytopenic purpura in five juvenile cotton-top tamarins is described. The presentation and morphology of this syndrome is distinct from any other reported gastrointestinal disease reported in tamarins. Traditional etiologies such as viruses, ingested toxins, Campylobacter, Salmonella and Yersinia and Clostridium difficile are not considered likely etiologic agents. Nontraditional etiologies such as anaerobes or pathologic strains of Escherichia coli are now being considered. This syndrome is of potential significance to ongoing research into the etiology of idiopathic tamarin colitis.

Anemia↗