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At least 415 records · Page 23Linked to original sources

Metastatic carcinoma with an unknown primary.

The patient is a 54-year-old white female who was well until 3 weeks prior to admission when she noted vague right upper quadrant pain exacerbated by meals. She lost 12 lbs over that period of time. She complained as well of posterior scalp, left hip, and back pain on initial presentation. Physical examination at the time of admission to hospital showed a middle-aged female in no acute distress. Her vital signs were normal. There was a 1.5 X 1.5-cm firm, tender nodule over the occiput. There was no peripheral adenopathy. The breasts, lungs, and heart were normal. The liver was 14 cm in span. The remainder of the physical examination including a pelvic examination was unremarkable. On admission, the only abnormal laboratory studies were SGOT 106, SGPT 139, and alkaline phosphatase 190. Her chest X ray, flat plate of the abdomen, and mammograms were all normal.

Adenocarcinoma↗

Improved detection of metastatic Ewing's sarcoma with the use of bone marrow scintigraphy.

Prognosis in Ewing's sarcoma is inversely related to the extent of the disease at the time of presentation. The most common sites of metastases are the lungs and skeleton. Bone marrow metastases may be present but clinically silent. We report the use of Technetium (Tc)-99m bone marrow scintigraphy to detect sites of marrow involvement by metastatic Ewing's sarcoma. This method of evaluation allowed identification of sites of involvement by Ewing's sarcoma that were not available by any other method of evaluation. In several instances, information provided by this method was pivotal in the management of these patients. Based on this small series of patients, bone marrow scintigraphy appears to be a sensitive modality in the detection of metastatic disease in patients with Ewing's sarcoma. Better understanding of the role of bone marrow scanning and its correlation with other diagnostic procedures in Ewing's sarcoma will require further study.

Adolescent↗

[Total or partial iliac reconstruction using allografts from the bone bank].

The reconstruction of massive pelvic defects following resection for tumour or damage from major trauma presents great technical difficulty. We have used cryopreserved allografts in patients to restore the normal anatomy and avoid major resection, such as a hemipelvectomy. This method avoids major limb shortening and impairment of function which occurs after trochantero-iliac or trochantero-sacral arthrodesis. Resection of tumour must be meticulous and complete in order to achieve a sound bed for the allograft. No problems were encountered in reattaching muscle insertions to the allograft, and skin healing was achieved without difficulty in all cases but one. In 2 patients involvement of nerve roots by tumour required their resection, with paralysis of the affected limb, but the overall function was satisfactory. In 10 patients removal of the hip joint was needed, and a total replacement was undertaken with cementing of the acetabular component into the allograft. Only one patient required a further operation because of partial necrosis of the allograft. Demineralisation was noted in some parts of the allograft between 18-20 months, but did not appear to affect function.

Adult↗

Tuberculosis of the ischiopubic ramus. A report of five cases.

Five cases of tuberculosis of the ischiopubic ramus are reported. All presented with abscesses. Treatment by simple curettage and INH, rifampicin and ethambutol given for 18 to 24 months gave satisfactory results in the 4 patients who were children. The one adult had severe disruption of the symphysis pubis, and sacroiliac involvement; a good result was obtained after bone grafting and fixation with a plate.

Adult↗

Irregularity of the apophysis of the ischial tuberosity.

We report five cases of irregularity of the apophysis of the ischial tuberosity (Kremser's disease). In four, plain radiographs showed that the density of the radiolucent area increased within several months of a minor injury. Serial computerised tomography demonstrated new bone formation across the widened apophyseal plate, although there was no change in the shape or density of the apophysis itself. The separation repaired and remodelled spontaneously within a year. In one case, CT showed that the apophyseal ossification centre was smaller than that on the opposite side. Our findings showed that in four cases the irregularity of the apophysis of the ischial tuberosity may have been caused by an avulsion fracture, but the appearance in the fifth case was a normal variant of the ossification centre.

Adolescent↗

Tumoral calcinosis.

A patient with tumoral calcinosis involving the buttock and ischial bone is presented. Bone marrow involvement and a pattern of septal enhancement on MR imaging after intravenous administration of Gd-DTPA were very suggestive of a diagnosis of a chondro(sarco) matous musculoskeletal tumor. The absence of an underlying metabolic disorder, the appreciation of fluid-calcium levels within the lesion and knowledge of the macroscopic and microscopic appearance of this disorder have led to the correct diagnosis in this case.

Bone Diseases↗

Conservative operations for pelvic bone tumours.

This paper outlines our experience of partial pelvic resection for benign tumours or those of low grade malignancy. The entire half of the pelvis may be removed with preservation of the limb. Pelvic resection must only be undertaken when the surgeon is sure that the removal of the tumour will be as radical as in an inter-ilio abdominal amputation. Various methods of creating rest for the superior end of the femur against the remaining parts of the pelvic bones are shown. Special attention is devoted to preservation of the limb movement and restoration of the locomotor function of the leg.

Acetabulum↗

Selective arterial embolisation in aneurysmal bone cysts.

The treatment of three cases of aneurysmal bone cyst by selective arterial embolism is described. Two cases had involvement of the pelvis and one of the knee. The 2-year follow up has been promising. Radiologically the lesion has been arrested with increased density of the cyst wall and intra-cystic trabecular new bone formation. Pain relief has been complete and up to now no surgical treatment has been required.

Adult↗

Idiopathic synovial chondromatosis in two unusual sites: inferior radioulnar joint and ischial bursa.

Synovial chondromatosis is a rare disorder of unknown cause characterized by multiple calcific bodies in the vicinity of the affected joint. It is most commonly seen in the knee, hip, elbow, and shoulder. We describe three cases of synovial chondromatosis in two extremely uncommon sites, the inferior radioulnar joint and the ischial bursa, and review the literature on the subject. The characteristic radiographic appearance, even if in an uncommon location, should prompt the radiologist to suggest the correct diagnosis preoperatively.

Adult↗

The "pelvic digit"--an unusual developmental anomaly.

Five cases of a rare developmental anomaly involving extraskeletal bone formation are described--four in the pelvis and one arising from the 12th rib. Three of these bony growths, called "Pelvic digits" had well developed "joints" or pseudoarticulations. The similarity of this anomaly to posttraumatic myositis ossificans and avulsion injuries of the pelvis (rectus femoris) is pointed out and a differential diagnosis offered.

Adult↗