Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Intestine, Small”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 415 records · Page 23Linked to original sources

Arteriovenous malformations of the small intestine.

Arteriovenous malformations of the small intestine are an uncommon cause of gastrointestinal hemorrhage. When we reviewed the records of 406 patients admitted to the hospital because of gastrointestinal blood loss, we found nine patients who had AVMs of the small intestine. We have developed an algorithm that presents a rational diagnostic approach to patients with hemorrhage from the small intestine. Single contrast barium roentgenograms were not helpful in this series. Endoscopy is not helpful unless the scope can be passed to the area of involvement. Arteriography is the most helpful diagnostic maneuver and should be considered early in the work-up for suspected intestinal AVMs. In addition, arteriography can be useful in localizing the precise area of bleeding so that resection can be limited to the involved areas.

Aged↗

[Regulation of cholesterol absorption in human and rat small intestine epithelial cells].

Cholesterol absorption in human small intestine organ culture and rat small intestine epithelial cell culture IRD-98 has been studied using [14C] cholesterol, [3H] cholesterol and [14C] sitosterol. It has been found that cholesterol absorption is a dose- and time-dependent process, while sitosterol absorption is not and makes up to about 25% of the total cholesterol absorption. Cholesterol absorption appeared to be a specific process. The endocytosis inhibitor monensin decreased specific cholesterol absorption by 37%. Cholesterol absorption was examined under different conditions influencing cholesterol metabolism in the cell. Loading of IRD-98 cells with non-lipoprotein cholesterol caused a dose-dependent decrease of cholesterol absorption. The inhibitor of acyl coenzyme A:cholesterol acyl transferase (ACAT), compound Sandoz 58-035, had a similar effect on cholesterol absorption. Lovastatin, an inhibitor of 3-hydroxymethyl-3-glutaryl coenzyme A (HMG-CoA) reductase, stimulated cholesterol absorption in a dose-dependent manner. Loading of cells with cholesterol, lovastatin and Sandoz 58-035 had no effect on sitosterol absorption. The possibility has been demonstrated of using human small intestine organ culture and rat small intestine epithelial cell culture IRD-98 as models for studying cholesterol absorption.

Adolescent↗