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At least 415 records · Page 23Linked to original sources
PubMed2003

Effects of mothers' autoimmune disease during pregnancy on learning disabilities and hand preference in their children.

OBJECTIVES: To determine whether children (and particularly sons) of women with systemic lupus erythematosus (SLE) during pregnancy are more likely to have learning disabilities (LD) and be non-right-handed, and if maternal disease variables (ie, presence of maternal antibodies, disease activity level, and use of corticosteroids) predict the prevalence of LD in offspring. DESIGN: Case-controlled study with subjects matched by age and sex. PARTICIPANTS: We studied 58 children whose mothers had SLE during pregnancy and 58 children of healthy mothers. Measures Data collected included maternal disease variables in women with SLE during their pregnancies. All children took a standardized intelligence test (Wechsler Intelligence Scale for Children-III) and completed a modified version of the Edinburgh Hand Preference Questionnaire. They also took standardized tests of reading, arithmetic, and writing achievement. Learning disability was defined as having an academic achievement score of at least 1.5 SDs below the Full-Scale IQ. RESULTS: Sons of women with SLE were significantly more likely to have LD than daughters of women with SLE or children of either sex in the control group. Maternal SLE was not associated with non-right-handedness in sons or daughters. The presence of anti-Ro/La antibodies and disease activity (flare) in mothers during pregnancy were significantly related to higher prevalence of LD in offspring. CONCLUSIONS: Autoimmune disease in women during pregnancy is associated with an increased risk for LD in their sons. Maternal antibodies, particularly anti-Ro/La, likely affect the fetal brain of male offspring and result in later learning problems. These findings should promote greater awareness of the risk for LD in sons of women with autoimmune disease and the possible need for early educational intervention in those children.

Antibodies, Antinuclear↗
PubMed1979

Clinical utility of the WISC-R and the French Pictorial Test of Intelligence with native American primary grade children.

Cultural bias and the clinical utility of the WISC-R and French Pictorial Test of Intelligence were evaluated using scores of 22 male and 22 female Navajo primary grade children. There were no significant differences in performance on either test according to sex. As expected, the Verbal IQ and Full Scale IQ of the WISC-R and the Deviation IQ of the French provided significantly depressed estimates of ability. A prorated Performance IQ might be the least depressed measure of potential among these children.

Child↗
PubMed1996

[Articulatory function in patients receiving glossectomy followed by reconstruction with a recto-abdominal myocutaneous free flap].

Postoperative articulatory functions of patients with tongue cancer have been improved by reconstructive surgery with a radial forearm or recto-abdominal myocutaneous free flap. We examined the postoperative articulatory functions of 10 patients who received reconstruction with a recto-abdominal myocutaneous free flap after glossectomy. The functions were investigated by standardized tests, i. e. a quentionnaires, the 100 Japanese monosyllable speech intelligibility test and a single-word intelligibility test. A confusion matrix was obtained from the results of the monosyllable test. On the basis of resection sites, the present cases were divided into two types: an anterior type and a lateral type. The results are summarized as follows. There was no significant difference in the results of the quentionnareis between the two types. The mean score of the 100 Japanese monosyllable speech intelligibility test in cases of the anterior type was 48% and in those of the lateral type it was 62%. The mean score of the single-word intellibibility test in cases of the anterior type was 75% and in those of the lateral type it was 83%. In cases of the anterior type, dental and alveolar sounds were often confused with fricatives, whereas in the lateral type, velars sounds were often confused with affricates or flaps. These results suggest that our classification based on resection site was useful for investigating postoperative articulatory functions after partial glossectomy.

Adult↗
PubMed2001

Cognitive functions of young adults who survived childhood cancer.

Neuropsychological tests were used to determine the cognitive functioning of adult long-term survivors treatedfor childhood cancer Disease onset before the age of 5 was related to lower test scores in intelligence tests, several memory tests, and motor function tests. The cranial irradiated survivors displayed more difficulties, especially in short-term memory tests and the Wechsler Adult Intelligence Scale Digit Symbol Test as compared to nonradiated survivors. No statistically significant differences in test scores were observed between different forms of cancer The results of this study are consistent with the notion that those memory types that demand special attention and motor speed functions are especially vulnerable to cancer and its treatment.

Adolescent↗
PubMed1989

IQ is irrelevant to the definition of learning disabilities.

The purpose of this article was to examine the logic and the empirical data supporting the proposition that intelligence tests are not necessary for the definition of a learning disability. Four assumptions of the use of IQ test scores in the definition of learning disabilities were examined. These assumptions were (a) IQ tests measure intelligence; (b) intelligence and achievement are independent, and the presence of a learning disability will not affect IQ scores; (c) IQ scores predict reading, and children with low IQ scores should be poor readers; and (d) reading disabled children with different IQ scores have different cognitive processes and information skills. It was argued that IQ scores measure factual knowledge, expressive language abilities, and short-term memory, among other skills, and that because children with learning disabilities have deficits in these areas, their scores may be spuriously low. It was also shown that some children with low IQ scores can be good readers, indicating that low IQ scores do not necessarily result in poor reading. Empirical evidence was presented that poor readers at a variety of IQ levels show similar reading, spelling, language, and memory deficits. On logical and empirical grounds, IQ test scores are not necessary for the definition of learning disabilities.

Achievement↗
PubMed2000

Borderline personality disorder. Neuropsychological testing results.

Earlier clinical hypotheses regarding borderline personality disorder, based on projective psychological testing and intelligence tests, are examined. Recent findings of comparative deficits in this population in the domains of verbal and visual memory as well as visual perception are reviewed, together with clinical relevance. Efforts to examine the way individuals with this disorder process emotion-laden material are discussed, with suggestions for further research.

Affect↗
PubMed2005

In utero exposure to background levels of polychlorinated biphenyls and cognitive functioning among school-age children.

Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants. In utero exposure to background levels of PCBs has been associated with intellectual impairment among children in most, but not all, studies. The authors evaluated prenatal PCB exposure in relation to cognitive test (intelligence quotient (IQ)) scores on the Wechsler Intelligence Scale for Children at age 7 years. Pregnant women were recruited from 12 US study centers from 1959 to 1965, and their children were followed until age 7 years (the Collaborative Perinatal Project). Third trimester serum was analyzed for PCBs in 1997-1999 for 732 women selected at random and for an additional 162 women whose children had either a low or a high IQ score. The PCB-IQ association was examined in multivariate models. Among those in the lowest exposure category (<1.25 microg of PCB/liter of serum), the fully adjusted mean IQ score was 93.6 (standard error: 1.8); among those in the highest category (> or =5 microg of PCB/liter), the mean IQ was 97.6 (standard error: 1.2); and overall the increase in IQ per unit increase in PCB level (microg/liter) was 0.22 (95% confidence interval: -0.28, 0.71). In these data, in utero exposure to background levels of PCBs was not associated with lower IQ at age 7 years.

Abnormalities, Drug-Induced↗
PubMed1988

Prediction of fine motor skills of children having language and speech disorders.

Relationships between the fine motor skills and linguistic abilities of 37 developmentally delayed children, ages 5 to 9 yr., were studied using a battery of expressive and receptive language tests, a measure of fine motor performance, a dichotic listening test, and individual intelligence tests. While IQs and MAs were not related to fine motor skills, both expressive and receptive language test scores showed moderate to moderately high correlations, the highest single relationship being the Test for the Auditory Comprehension of Language. In concert with CAs, a dichotic right-ear test score, the Auditory Comprehension Test, predicted fine motor-skill indices substantially; R = .80. Strong relationships appear between linguistic and fine motor skills in an age group not previously investigated and at higher levels than reported in studies of infants and very young children. Dichotic results were abnormal in a majority of the children.

Child↗
PubMed2004

Assessing potentially gifted students from lower socioeconomic status with nonverbal measures of intelligence.

The screening and identification of gifted students has historically been conducted using verbal measures of intelligence. However, the underrepresentation in gifted programs of culturally diverse children, who may have limited English proficiency or cultural values different from those measured in traditional intelligence tests, has prompted researchers to consider other measures. Nonverbal measures of intelligence have been utilized to increase the number of gifted children from diverse backgrounds. Researchers in the current study sought to increase the number of culturally diverse gifted students at a rural public school enrolling predominantly African-American students from low socioeconomic homes. 169 students in Grades 2 through 6 were assessed using three nonverbal measures of intelligence: the Culture-Fair Intelligence Test, the Naglieri Nonverbal Abilities Test, and the Raven Standard Progressive Matrices. The scores on these nonverbal measures indicated that the Culture-Fair Intelligence Test and the Raven Standard Progressive Matrices identified more students than the Naglieri Nonverbal Abilities Test. A discussion of the results and implications for research are presented.

Child↗
PubMed1991

Neonatal hyperbilirubinemia and physical and cognitive performance at 17 years of age.

To estimate the effect of neonatal hyperbilirubinemia on long-term cognitive ability in full-term newborns with a negative Coombs test, we performed a 17-year historical prospective study of 1948 subjects. Intelligence tests and medical examinations performed at the military draft board were stratified according to serum bilirubin concentration. A logistic regression analysis was used to adjust for the confounding effects of gestational age, birth weight, Apgar score, ethnic origin, socioeconomic class, paternal education, birth order, and the administration of phototherapy and exchange transfusion. No direct linear association was shown between neonatal bilirubin levels and intelligence test scores or school achievement at 17 years of age. However, the risk for low intelligence test scores (IQ score less than 85) was found to be significantly higher (P = .014) among full-term male subjects with serum bilirubin levels above 342 mumol/L (20 mg/dL) (odds ratio, 2.96; 95% confidence interval, 1.29-6.79). This association was not observed among female subjects. We conclude that severe neonatal hyperbilirubinemia, among full-term male newborns with a negative Coombs test, could be associated with lower IQ scores at 17 years of age.

Adolescent↗
PubMed1996

Profiles of Hispanic adolescents and adults on the Holland Themes and Basic Interest Scales of the Strong Interest Inventory.

The Strong Interest Inventory and its predecessors have been the subject of decades of research. Many studies have used Holland's Six General Occupational Themes, and some have explored the 23 Basic Interest Scales. The literature addresses IQ in vocational counseling and includes studies relating Holland's themes and the 23 interest scales. The subjects included a nationwide sample of 894 13- to 65-yr.-olds tested during the standardization of the Kaufman Adolescent and Adult Intelligence Test. Multivariate analyses of variance were conducted with age, gender, and IQ on the intelligence test as independent variables, and the six Holland themes and 23 interest scales as dependent variables. IQ was related to Investigative and Artistic themes. Individuals with high IQs scored nearly one standard deviation higher than individuals with low IQs on each of these scales. A number of Basic Interest Scales correlated significantly with IQs, most of which were associated with either the Investigative or Artistic themes. Correlations of IQ with Holland Themes and scores on Basic Interest Scales were observed for both genders. The information gained from an individually administered intelligence test can enhance interpretation of the Holland themes and interest scales for vocational counseling.

Adolescent↗
PubMed2003

[Breast feeding and intelligence].

INTRODUCTION: In several studies a positive association between breastfeeding and intellectual development in childhood has been suggested. However, the association between breastfeeding and adult intelligence is unknown, and the purpose of the present study was to investigate the relationship between duration of breastfeeding and intelligence in young adulthood. MATERIAL AND METHODS: A prospective longitudinal study based on the Copenhagen Perinatal Cohort. A mixed-sex sample comprising 973 individuals with a mean age of 27.2 years was assessed with a clinical intelligence test (WAIS) and an all-male sample comprising 2280 individuals was assessed with a military intelligence test (BPP) at the mean age of 18.7 years. Based upon duration of breastfeeding, the samples were divided into five categories. Thirteen potential confounders were included as covariates: Parental social status and education, single mother status, mother's height, age, weight gain during pregnancy, and cigarette consumption during the third trimester, number of pregnancies, estimated gestational age, birth weight, birth length, and indexes of pregnancy and delivery complications. RESULTS: Duration of breastfeeding was associated with significantly higher scores on both the verbal and performance parts of the WAIS. With regression adjustment for potential confounding factors, the full scale IQs were 99.4, 101.7, 102.3, 106.0, and 104.0 for breastfeeding durations of < or = 1 month, 2-3 months, 4-6 months, 7-9 months, and > 9 months (p = 0.003). The corresponding mean scores for the BPP were 38.0, 39.2, 39.9, 40.1, and 40.1 (p = 0.01). Thus, the mean test scores suggested a dose-response relationship for breastfeeding during the first nine months of life and adult intelligence. DISCUSSION: Independent of a wide range of possible confounding factors, a significant positive association between duration of breastfeeding and intelligence was observed in two independent samples of young adults, assessed with two different intelligence tests. Although duration of breastfeeding may correlate with maternal intelligence and with the quality of mother-child interaction, these findings suggest that nutrients in breastmilk may have long-term positive effects on cognitive and intellectual development.

Adult↗
PubMed1993

[Changes in positive mood states by analytic and creative information processing].

Reviews concerning research on the influence of mood on behavior show (a) that mainly the influence of mood on behavior was investigated and (b) that achievements in memory and cognitive tasks were of central concern (Fiedler, 1988; Isen, 1987). Social behavior was analyzed as a function of these factors. Recent reviews restrict themselves to positive feeling states. Summarizing, Fiedler (1988) describes the information processing style in positive feeling states as "loosening" to capture its qualitative aspects. This study investigates the opposite direction of influence, i.e. the effect of cognitive style on positive feeling states. This study restricts itself to positive feeling states. The compatibility thesis which postulates a necessary interaction of feeling state and information processing style is tested. Equivalent states and productions have to go together to generate the mood effects. In a 2 x 2 x 5 mixed design 70 female students (non-psychologists) served as subjects. Using a 20-minute mood induction procedure (autobiographical recollection methodology) a positive or neutral feeling state was elicited in half of the participants. During the next 10 minutes half of each group worked either on a verbal creativity test (Schoppe, 1975) or on an intelligence test (Amthauer, 1973) to establish an creative or analytic style of information processing. Repeated sampling of a measurement repetition factor served as baseline assessments, manipulation checks, and measurements of the feeling states during the task completion of the creativity or intelligence test. The feeling states were assessed by means of a short version (BSK-1982) of the "Eigenschaftswörterliste" (Janke & Debus, 1978). The results confirm the compatibility thesis. Only the group in which a positive feeling state and a creative processing style interact reported a positive mood throughout the task completion. Unexpectedly, a slight deterioration of mood was found in the group with a neutral feeling state and analytic reasoning, suggesting that the neutral mood induction might in fact, elicit a mild negative feeling state and that the compatibility thesis might, also be applicable to the field of negative emotions.

Adult↗
PubMed2003

Sex differences in verbal and spatial ability reconsidered in relation to body size, lung volume, and sex hormones.

Sex differences in verbal and nonverbal abilities were reconsidered in relation to bodily measures and sex hormones in Turkish university students. Perceptual-verbal ability was evaluated using As Test. To assess the nonverbal abilities, the mental rotation test and Cattell's Culture Fair Intelligence Test were used. As expected, the 53 women performed better than men on the As Test; 79 men had a higher mean than the 53 women on the mental rotation task; there was no sex difference on Cattell's IQ Test. Cattell IQs correlated only with tidal volume of lungs. Scores on the As Test did not show significant correlations with body size and lung capacities. Mental rotation was significantly correlated with height, weight, and lung volume. With covariates of height, weight, and vital capacity, sex differences in mental rotation completely disappeared, but the difference on the As Test increased while Cattell IQ remained sex-neutral. With testosterone as covariate, the sex difference on the As test increased but on the mental rotation task disappeared; Cattell IQ was sex-neutral. With covariates of estradiol and progesterone, sex differences on the As test disappeared; mental rotation scores and Cattell IQ were not influenced. Under a combined covariation of height, weight, and testosterone, sex differences in mental rotation reversed, women scoring better than men; after adding estradiol or progesterone instead of testosterone to this model, sex differences on mental rotation completely disappeared, but verbal ability and Cattell IQ were not changed. These results suggest that Cattell's Culture Fair Intelligence Test is unique in resistance to sex differences; perceptual-verbal ability was the most sex-specific mental trait but with dependence on estradiol; mental rotation, on the contrary, was least sex-specific, depending on body size, lung volume, sex hormones, and their combined actions, which explains women's better performance.

Adolescent↗
PubMed2005

Maternal stress, social support and preschool children's intelligence.

BACKGROUND: Despite some research suggesting maternal stress may be associated with cognitive impairment in preschool children, there has been little direct investigation of the association between maternal stress, social support and children's intelligence. AIM: To determine whether maternal stress and social support during pregnancy and during the child's early years of life are associated with the intelligence test performance of preschool children. STUDY DESIGN: Five hundred and fifty European mothers and children enrolled in the Auckland Birthweight Collaborative Study at birth were interviewed when the child was 3 1/2 years of age. SUBJECTS: All children were full term gestation and approximately half the sample were small for gestational age at birth (SGA = birthweight < or = 10th percentile). OUTCOME MEASURE: The cognitive ability of children aged 3 1/2 years was assessed using the Stanford Binet Intelligence Scale 4th Edition. RESULTS: In the total sample, maternal stress and lack of social support during pregnancy were significantly associated with lower intelligence test scores of children. In the group of SGA children, maternal stress post pregnancy was significantly associated with lower intelligence test scores in children. There is evidence that for some children the presence of good social support for mothers may reduce the negative effects of maternal stress on children's cognitive development. CONCLUSION: Maternal stress and lack of social support appear to be associated with lower intelligence test scores of preschool children. Social support may attenuate some of the negative effects of maternal stress on intelligence in children born small for gestational age.

Child Development↗