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PubMedDate not supplied

Synthesis of new n-substituted cyclic imides with expected anxiolytic activity. XXI. Derivatives of 1-acetyldibenzo-[e.h]-bicyclo[2.2.2]-octane-2,3-dicarboximide.

The preparation of a number of new N-substituted derivatives of 1-acetyldibenzo-[e.h]-bicyclo[2.2.2]-octane-2,3-dicarboximide with an expected anxiolytic activity is described.

Anti-Anxiety Agents↗

PubMedDate not supplied

Synthesis of new n-substituted cyclic imides with potential anxiolytic activity. XXIII. Derivatives of 2'-chlorodibenzo[e.h]bicyclo[2.2.2]octane-2,3-dicarboximide.

The preparation of a number of derivatives of dibenzo[e.h]bicyclo[2.2.2]octane-2,3-dicarboximide with an expected anxiolytic activity is described.

Anti-Anxiety Agents↗

PubMed1954

[Effect of maleic acid imide (N-ethylmaleimide) on viral multiplication].

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Ethylmaleimide↗

PubMedDate not supplied

Synthesis of new N-substituted cyclic imides with an expected anxiolytic activity. XXIV. Derivatives of N-hydroxy-1-methoxybicyclo[2.2.2]oct-5-ene-2,3-dicarboximide.

The preparation of a number of derivatives of N-hydroxy-1-methoxybicyclo[2.2.2]oct-5-ene-2,3-dicarboximide with an expected anxiolytic and antidepressive activity has been described.

Animals↗

PubMedDate not supplied

Synthesis of new N-substituted cyclic imides with potential anxiolytic activity. XXV. Derivatives of halogenodibenzo[e.h]bicyclo[2.2.2]octane-2.3-dicarboximide.

The preparation of a number of derivatives of dibenzo[e.h]bicyclo[2.2.2]octane-2.3-dicarboximide with an expected anxiolytic activity.

Animals↗

PubMed1991

Synthesis and immunopharmacological analysis of selected derivatives of N,N'-bis-/3-aziridine/butanoylalkylenediamines and imides of 3-aziridinesuccinic acid. I.

A series of aziridinederivatives of N,N'-bis-butanoylalkylenodiamines (Scheme 1, 1-4) and aziridinederivatives of substituted succinic acid (Scheme 2, 16-19) was obtained. Pharmacological analysis revealed that these compounds were immunotropic, of marked suppressive effect (PFC, RFC, circulating immunoglobulins). Outstanding in this group was phenyloimide of succinic acid (prep. 16) which reduced PFC and RFC number but increased the level of circulating IgG.

Animals↗

PubMed1977