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History, etymology, and fallacy: attitudes toward male masturbation in the ancient Western world.

This article examines the attitudes toward male masturbation in the ancient western world. More specifically, this work deals with ancient Egypt, Greece, and Rome. By comparing each epoch and geographic region, intolerance of autoerotic activity can be seen. Although there is a pattern of intolerance, the act of masturbation is always viewed provisionally. In addition, by examining these three periods of history not only can attitudes be scrutinized, but also it can be seen quite clearly that there was no golden age of sexuality: The attitude of accepted and encouraged unlimited and varied sexual practices does not exist in the ancient western world. As in many other cultures in various stages of history, procreative sexuality is the dominating theme. Thus, current attitudes of sex are derived from, and still survive due to the influence of, ancient western civilization.

Attitude↗

Primary femininity and female genital anxiety.

Primary femininity implies that female development proceeds along lines that generate anxiety about damage and loss similar to the fears of castration that trouble males. The female fears are classified as fear of painful penetration, fear of loss of pleasure, and fear of loss of procreative function. The first two fears are illustrated with clinical material showing the ways in which they manifest themselves in adult women.

Adult↗

Klinefelter's syndrome.

Klinefelter's syndrome is the most common genetic cause of human male infertility, but many cases remain undiagnosed because of substantial variation in clinical presentation and insufficient professional awareness of the syndrome itself. Early recognition and hormonal treatment of the disorder can substantially improve quality of life and prevent serious consequences. Testosterone replacement corrects symptoms of androgen deficiency but has no positive effect on infertility. However, nowadays patients with Klinefelter's syndrome, including the non-mosaic type, need no longer be considered irrevocably infertile, because intracytoplasmic sperm injection offers an opportunity for procreation even when there are no spermatozoa in the ejaculate. In a substantial number of azoospermic patients, spermatozoa can be extracted from testicular biopsy samples, and pregnancies and livebirths have been achieved. The frequency of sex chromosomal hyperploidy and autosomal aneuploidies is higher in spermatozoa from patients with Klinefelter's syndrome than in those from normal men. Thus, chromosomal errors might in some cases be transmitted to the offspring of men with this syndrome. The genetic implications of the fertilisation procedures, including pretransfer or prenatal genetic assessment, must be explained to patients and their partners.

Anthropometry↗

Different mechanisms of mitotic instability in cancer cell lines.

Chromosomes of human malignant tumours display not only structural recombinations but also a wide variety of mostly non-random numerical aberrations. However, only little is known about the mechanisms leading to recurrent aneuploidies. We therefore investigated whether the malsegregation of specific chromosomes is due to a defect of the mitotic spindle apparatus. We analyzed mitoses of cell lines of six gliomas and of one breast carcinoma by combined immunohistochemistry and fluorescence in situ hybridization for non-disjunction of chromosomes 7, 8, 10, 12, 17, and 18 and observed three different phenomena. i) Five of six glioma cell lines showed a bipolar spindle but displayed a chromosome-specific malsegregation of all chromosomes studied with high but significantly different frequencies. Chromosomes 7 and 8 showed non-disjunction in about 75 and 50%, respectively. Although chromosomes 10, 12, 17, and 18 displayed equal separation during mitosis in 72, 86, 73, and 78%, respectively, a relevant percentage of an average of 24% of dividing cells showed even malsegregation of these chromosomes. ii) Only one of the glioma cell lines displayed multipolar spindles in one-third of the investigated cells resulting in non-specific aneuploidy. iii) The breast cancer cell line MCF7 displayed a bipolar spindle, but high frequencies of non-disjunction of all six investigated chromosomes but without preferential loss or gain of specific chromosomes indicating a different mechanism of chromosome malsegregation. In a small percentage of mitoses the chromatids of both homologous chromosomes were not separated mimicking the mechanism in the first meiotic division. This mechanism of double non-disjunction, not detectable by conventional cytogenetic analysis, procreates cell clones with genomic separation for particular chromosomes resulting in homozygosity for mutations which had been present heterozygously in the initial tumour cells.

Breast Neoplasms↗

Bioethics in artificial reproduction in the Muslim world.

In Islam infertility and its remedy with the unforbidden is allowed and encouraged. It is essential if it involves preservation of procreation and treatment of infertility in one partner of the married couples. This is applicable to artificial reproduction which is one line of treatment of infertility.... The prevention and treatment of infertility are of particular significance in the Muslim World. The social status of the Muslim woman, her dignity and self-esteem are closely related to her procreation potential in the family and in the society as a whole. Childbirth and rearing are regarded as family commitments and not just biological and social functions.

Abortion, Eugenic↗

[Selenium in the full-term and premature newborn infant].

The following observations can be made on the basis of findings relating to selenium in serum samples taken from 55 neonates (35 born at term and 20 born pre-term): 1) the blood concentration of selenium in neonates born at term showed no substantial difference to that reported by other authors; moreover, there were no sex or birthweight-dependent variations, and no correlations were found with either the mother's age or the mode of engendering procreation; 2) the blood concentration of selenium in neonates born pre-term was 30% lower than that found in neonates born at term; it was correlated with gestational age and birthweight, but not with sex, mother's age or the mode of engendering procreation. It will be worthwhile continuing these tests in order to identify possible therapeutic uses of selenium in cases of deficiency.

Birth Weight↗

Procreational attitudes and behaviour: some problems of genetic counseling effectiveness.

Some results of the study of genetic counseling effectiveness, conducted in 1980-1981, are the subject of this paper. The main group under the study consisted of 187 families with the Down syndrome child, who in the period 1974-1979 visited the Genetics Clinic of NRIMC and received genetic counseling there. The relation between genetic counseling and the procreation sphere among the studied families is presented. Procreation plans have been analysed with special emphasis made on changes related to genetic counseling. The influence of this counseling as a factor reducing fear of having a child with a disease has been confirmed. It has been found that procreation plans have changed after the counseling especially among those women who did not plan pregnancy earlier. Some psychological aspects of genetic counseling as are essential for forming procreation attitudes of the consulting families have also been discussed.

Abortion, Induced↗

Genetic concepts in Greek literature from the eighth to the fourth century B.C.

A review of the concepts of genetics found in epic, historical and dramatic ancient Greek writings from the eighth to the fourth centuries B.C., is presented. The derived data suggest that the development of genetical concepts and ideas started with the praise of the heroes' divine or noble origin in Homer's epic poems (eighth century B.C.). It continued in the tracing of the descent and vicissitudes of the families of the Greek gods and the common ancestry of the Greek tribes as described in Hesiod's genealogical poems (around 700 B.C.), in the statement of descent and dual parenthood of leaders and kings in the books of Herodotus and Xenophon (fifth and fourth centuries B.C.), and in the concern about the lineage of the tragic figures in Greek drama (fifth century B.C.). The genetical concepts expressed in these writings most probably reflected popular notions of that time. They must, therefore, have been the basis of the perceptions and theories on heredity and procreation expressed by the ancient physicians and philosophers in the fifth and fourth centuries B.C., which in turn influenced the development of genetics for many centuries.

Child↗

[Poisons for reproduction in work environment].

This article describes the lawful bases of the reprotoxic risk management in work environment, and sets out the recommendations of the French Société de Médecine du Travail (occupational medicine) for the medical supervision of pregnant wage-earners exposed to toxic substances as far as foetal development is concerned. We start with the description of the lawful bases, clarifying the various types of classification of toxic substances for reproduction, the particular regulation applying to reprotoxic categories 1 and 2, particularly with regard to the labelling of these products, the prohibition of availability to the general public, the principles of prevention and the guarantees of remuneration of the pregnant women exposed to this risk. Then, we present the recommendations worked out by the Société Française de Médecine du Travail, with regard to the medical supervision of pregnant wage-earners. They include: evaluation of the risk on the work place, evaluation of exposure, be it external or internal, presentation of methods of calculation of values guides and of recommendations transmitted to occupational doctors, before and during the pregnancy of their patients. To conclude, it is important to remain rigorous with this reprotoxic risk, by referring to the lawful bases at our disposal and supporting the scientific bases following epidemiologic studies. Adequate information must be given to women but also men pf procreation age. In spite of a well-defined lawful framework, watchfulness is required with the new products put on the market and the new scientific data.

Female↗

A comparison of thematic apperceptions of sibling affiliation, conflict, and separation at two periods of adulthood.

The quality and stability of sibling relationships during adulthood were assessed by comparing TAT themes of sibling affiliation, conflict, and separation at the period of active child-rearing (CR) and the empty nest (EN). Thirty men and thirty women, divided equally between the two life stages, were randomly selected from a pool of individuals who had a same-sex, closely-spaced sibling. The Sibling Thematic Apperception Test (S-TAT) was developed to elicit underlying feelings about the relationship, because traditional methods of assessment have failed to tap its negative qualities. Contrary to previous findings, results showed no differences in affiliation or conflict theme frequencies between the CR and EN periods. Separation themes, however, were more frequent during the CR than the EN period, suggesting that concerns over separation from siblings reflect a developmental process which might be related to bonding with the family of procreation. Although there were no sex differences within life periods, women's stories about sisters across life period had more conflict themes than did men's stories about brothers.

Adult↗

Pregnancy in patients with Turner's syndrome: six new cases and review of literature.

Pregnancy in women with Turner's syndrome (TS) is an exceptional event, but is possible in 2% of cases. It can occur in patients with structural anomalies of the X chromosomes in which the Xq13-q26 region, containing the genes that are thought to control ovarian function, is spared; or in patients with a mosaic karyotype containing an 46,XX cell line, which preserves ovarian function. In our Centre we observed six cases of women with Turner's syndrome conceiving. Out of 13 pregnancies, there were six abortions and eight live-births; among the latter, four babies exhibited malformations. Reviewing the literature shows that out of 160 pregnancies which occurred in 74 women with TS, 29% ended in spontaneous abortion, 7% led to the perinatal death of the fetus, 20% gave birth to malformed babies (TS, Down's syndrome, etc.) and only in 38% of cases were healthy children born. This study suggests that the rare TS patients who are able to procreate should undergo prenatal diagnosis techniques. In sterile TS patients the use of artificial fertilization techniques is a possible solution.

Adult↗

[Regulation of reproductive medicine in North America or the Wild West of Medicine (Part I)].

The objective of this work is to offer a general introduction of the legal regulation of the Reproductive Medicine that is practiced in the United States of America. In the United States, besides the Federal Administration, there are also fifty state juridical instances who have competence in Assisted Reproduction subjects. The first section studies the limits of the Right to Reproduction. The American Constitution, interpreted by the Supreme Court, has been useful to establish the limits. Then, will be analyzed the reasons that have been taken by the legislator to adopt a permission with regard to issues appeared by the Medicine of the Fertility. Once studied the general context of the regulation of the Procreation Technology, it is exposed the state legislation and jurisprudence about the matter, and it is also made a review to the most relevant doctrine opinions of the american jurist in relation to Assistance to Reproduction. The cultural and juridical answers that these new clinic methods have used to control, improve or limit the reproduction capacity of human beings are almost as interesting as the Reproductive Technology. Contrary to what happens in Europe, where the legislator has firmly establish the regulation of the Reproductive Medicine since the late 80's, in North-America the lack of regulation has caused a free market where all kind of treatments of fertility are offered, just up to the point that an American author has called the sector "wild west of the Medicine".

Human Rights↗

[Cannabis: a harmless drug?].

Summarizing the literature of the past 25 years, we present a survey of the pharmacological effects of cannabis, which includes the pharmacological particularities of cannabis as a composition of substances with tetra-hydro-cannabinol as main component, the experimentally proved effects on animal cells, the experimentally and clinically proved damages to the central nervous system, respiratory tract, immune system and procreative system. The survey results in a warning: brain damage and dependency can be caused by cannabis and the resulting social consequences of an increasing consumption should not be underestimated.

Animals↗

Mummy was a fetus: motherhood and fetal ovarian transplantation.

Infertility affects 15 per cent of the world's couples. Research at Edinburgh University has been directed at transplanting fetal ovarian tissue into infertile women, thus enabling them to bear children. Fetal ovary transplantation (FOT) has generated substantial controversy; in fact, one ethicist deemed the procedure 'so grotesque as to be unbelievable' (1). Some have suggested that fetal eggs may harbour unknown chromosomal abnormalities: however, there is no evidence that these eggs possess a higher incidence of genetic anomaly than ova found in a healthy adult female. There is also concern that fetal egg children will be psychologically harmed by the knowledge of their special conceptual status. It will be demonstrated that special conceptual status in and of itself does not determine developmental success. Rather, psychological well-being is dependent upon how the family and child cope with the unique challenges inherent in FOT. Lastly, though considering FOT a legitimate method of family building, given the global population crisis the wisdom of procreational rights will be challenged. Inherent to this challenge is a re-evaluation of the treatment of infertility as a significant disease necessitating remedy.

Aborted Fetus↗

Chilling aspects of procreation.

Due to the possibility of storing gametes and pre-embryos, conflicts over the use of pre-embryos and post mortem insemination have found their way into the courts. Case law allows parties to conclude an agreement as to the destination of their pre-embryos in case of divorce or death. These agreements shall be presumed binding. However, if the agreement leads to forced procreation, this will not be allowed. If there is no agreement, or no agreement that can be enforced, the Davis rule will be applied: the right to procreate and the right to avoid procreation will be balanced against each other. If post mortem procreation is not prohibited, the role of a third party, i.e. the doctors or the future child, should also be taken into account.

Blastocyst↗

Omnis definitio periculosa est: on the definition of the term "embryo" in the Human Fertilisation & Embryology Act 1990.

In adopting a purposive interpretation of the definition of the term "embryo" in the Human Fertilisation & Embryology Act 1990, the Court of Appeal judgement in R(on the application of B. Quintavalle on behalf of Pro-Life Alliance) v. Secretary of State for Health effectively stifled democratic debate on the development of therapeutic cloning techniques. Instead of being evidence of the flexibility of of the statute to adapt to the rapid evolution of scientific techniques, the judgment bears witness to a certain dependence of the law on scientific criteria and moreover, raises the question of legitimate judicial function. Indeed, judges should not be seen to be deciding questions of social choice that should ultimately be decided through the democratic process. Although the purposive approach may be objectively justified, it is suggested that the appeal judges erred in their appreciation of the very purpose of the 1990 Act. It is argued that the Parliamentary debates in 1990 illustrate that the purpose of the 1990 Act does not go beyond the area of procreation and embryo research in this context. Consequently, it is claimed that no economy should have been made on a full democratic debate. By preventing such a debate, the Court of Appeal appears to admit that the law has become servile to the scientific, political and a fortiori economic, interests at stake.

Cloning, Organism↗

Sex on campus: a preliminary study of knowledge, attitudes and behaviour of university students in Delhi, India.

Eight hundred and eighty-seven students from two major universities in Delhi, India, were surveyed, using a self-administered questionnaire, about their sexual knowledge, attitudes and behaviour. The data show that female students seem to be rejecting traditional Indian repressive sexual standards of premarital and non-procreative sex and the gender differences are beginning to narrow. Despite their sexual awareness, the students were highly ignorant of the facts of life. Being male and married did not make them more knowledgeable.

Adult↗