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At least 415 records · Page 23Linked to original sources
PubMed1999

[A severe epicutaneous test reaction to the bufexamac in a hemorrhoidal therapeutic preparation].

HISTORY AND FINDINGS: A 49-year-old woman presented with acute perianal vesicular/bullous contact dermatitis. Other areas were over the trunk, face, neck and wrists. She reported occasional application of an ointment (Mastu S) to treat her hemorrhoids. INVESTIGATION: Patch tests (basic series, anal block, own ointment, local anesthetic, cosmetics) provoked strong vesicular and bullous reactions of persisting crescendo type, spreading far beyond the site of application, to Bufexamac, to a derivative of hydroxxamine acid, and to local applied ointment with mild or moderate antiinflammatory action. TREATMENT AND COURSE: A week after the patch tests there was a flare-up of the previous foci of dermatitis. These reactions subsided two days later after intravenous injection of prednisolone. The skin lesions healed after rapid reduction of the systemic treatment and local application of corticosteroids, bathing with tanning substances and basic preparations. CONCLUSION: While Bufexamac is not absorbed when applied rectally, perianal contamination may not be avoidable on intra-anal application and can produce sensitization.

Acute Disease↗
PubMed1989

Anal cancer incidence: genital warts, anal fissure or fistula, hemorrhoids, and smoking.

We conducted a study of 126 patients with anal and rectal squamous cell carcinoma and 372 randomly selected control subjects in the San Francisco Bay Area (CA) to test the hypothesis that these tumors are related to a history of anal intercourse, the presence of sexually transmitted diseases and other conditions of the anal area, treatment of these diseases or conditions, and history of use of cigarettes or other substances. The relative risk (RR) of cancer was elevated for men with a history of homosexual activity (RR = 12.4, P less than .001). However, after adjustment for other risk factors, this risk was reduced to 2.7 (P = .28). Risk was elevated for homosexual male patients who reported a history of genital warts (RR = 12.6, P = .03), anal fissure or fistula (RR = 9.1, P = .05), and cigarette smoking (RR = 1.9 for 20 pack-yr, P less than .001; RR = 5.2 for 50 pack-yr, P less than .001). (Pack-year is a unit of cigarette use equal to 365 packs.) There was also elevated risk for heterosexual male and female patients who reported a history of genital warts (RR = 4.4, P = .003), anal fissure or fistula (RR = 2.4, P = .03), and more than 12 episodes of hemorrhoids (RR = 2.6, P less than .001). These findings suggest that anal cancer risk is etiologically related to human papillomaviruses that cause genital warts. In addition, constant irritation, chronic inflammatory changes, and repeated epithelial regeneration that accompany noninfectious conditions may be related to risk of anal cancer. The higher risk among homosexual men is related to the higher prevalence of anal cancer risk factors for this group.

Adult↗
PubMed1984

Cryosurgery for life-threatening bleeding hemorrhoids in the elderly.

Forty-three elderly patients with massive bleeding of hemorrhoidal varices were treated by cryosurgery at a single outpatient session, using nitrous oxide gas, without premedication or anesthesia. The results were excellent in all but one patient, who had ulcerative colitis and required another session of cryotherapy following a recurrence of bleeding. There was no morbidity and no mortality. The patients have remained free of symptoms over follow-up periods ranging from two to five years. The authors believe that cryosurgery is the treatment of choice and indeed may sometimes be life-saving for elderly, poor-risk patients who are unfit for general anesthesia and surgical hemorrhoidectomy.

Aged↗
PubMed1983

He/Ne laser treatment of hemorrhoids.

In the treatment of first and second degree hemorrhoids, the He/Ne laser is an effective, simple and harmless clinical procedure, as an alternative to medical therapy or surgery. The authors describe the treatment carried out, indicating method and results of the application of red light 632.8 nm He/Ne laser. On the basis of therapy carried out at intervals of 5 days for a total of 6 treatments, a statistic control was reached. Results lead to the conclusion that greater or lesser laser radiation intensity lacks apparent importance. Treatment is effective in pain alleviation from the first session and final results are excellent as is shown by the table of statistics. The effects produced on rectum mucous are discussed offering a hypothetical explanation for its therapeutical action.

Adult↗
PubMed2002

Metastatic renal cell carcinoma presenting as a hemorrhoid.

Metastatic, noncolorectal carcinoma involving the anal canal is exceptionally rare, with only 3 cases being described in the medical literature. We report the case of a 53-year-old man with an anal mass clinically presenting as a large, thrombosed, internal hemorrhoid. The patient had a history of nephrectomy for renal cell carcinoma 9 years previously. The resected anal lesion was histologically identical to the primary tumor in the kidney, showing features of renal cell carcinoma of the clear cell type. To the best of our knowledge, this is only the fourth reported case of metastatic, noncolorectal carcinoma involving the anal canal and is the first report of a renal cell carcinoma metastasis to this site.

Anus Neoplasms↗
PubMed1976

[Treatment of internal hemorrhoids by the method of nonsurgical ligature combined with proctoglivenol].

In the Research Laboratory of Proctology with the clinic of the RSFSR Ministry of Health since 1974 a nonoperative ligature method was employed for treatment of 50 patients at high risk for this affection. A combined use of the nonoperative method and proctoglivenol suppositories is a rather effective therapeutic measure, which is indicated for treatment of hemorrhoids in patients, in whom operative intervention is contraindicated.

Age Factors↗
PubMedDate not supplied

[Towards a new classification of hemorrhoidal disease].

The generally accepted classification of hemorrhoids presents some rather wide gaps which may either be due to expressions of intrinsic limits or recent moves of the Colonproctology field. The authors of this paper would like to present their proposal for a new classification that considers the results of the National Multicentric Study that was performed in collaboration with nineteen centres and a total of 1,494 patients. In addition, a comparative study was conducted on the two forms of classification. Nineteen patients (1.28%) were considered unclassifiable with the new classification system while 49 were (3.29%) with the presently used one. These results were found significant with the MacNemar Chi-Square test. The description of type 2 and 3 in the new classification system was found useful in 69% of 2nd degree, 77% of 3rd degree and 28% of 4th degree using the present system. Acute events (type 5,6 and 7) proposed with the new classification were found in the present system with several different rates. We have also included the data taken from a national and international survey we conducted on the usefulness of the new classification that provoked intense debate within two of the most important national institutes. The result was the elaboration of a design on the new classification.

Europe↗
PubMed2000

[Treatment of hemorrhoids from the viewpoint of the gastroenterologist. Personal experience with the Ginkor Fort preparation].

Pathological changes in hemorhoid plexes are frequently occurring mainly in elderly. In development of this disease are mainly involved changes in the vessel wall, pressure changes in basin, disturbances in passage of stool and also infectious disease. Instead of the correction of the life-style in therapy are used locally-acting drugs whose basis are local anesthetics, spasmolytics, antiflogistics, antipruriginostics and corticoids in many combinations. The main aim of the orally administered drugs is influence of the vessel-wall tone, decrease of the capillary permeability, circulation betterment, decrease of the oedema and blockage of the inflammatory mediators. In the group of 45 patients is documented benefit in use of Gincor-fort in dose of 2 cps bid in first week and 2 cps daily in the second week of the treatment. We presume that this drug can influence all of above mentioned factors during the acute hemorrhoidal attack.

Acute Disease↗
PubMed2001

[Errors and complications in the treatment of hemorrhoids].

Long-term results of 724 hemorrhoidectomies were followed up from 6 months till 7 years. Various complications after operation were revealed in 172 (23.3%) patients. In 46 (26.7%) patients the failures were associated with unrecognized proctological diseases before operation, in 51 (30%)--with removal of hemorrhoids and in 63 (36.6%) patients the concomitant diseases of other organs and systems were the causes of complications.

Digestive System Diseases↗
PubMedDate not supplied

Double-blind, randomized clinical trial of troxerutin-carbazochrome in patients with hemorrhoids.

This multicenter, double-blind, randomised study was undertaken to determine the efficacy and safety of a combination of troxerutin 150 mg and carbazochrome 1.5 mg compared to carbazochrome alone in patients with acute uncomplicated hemorrhoids. Patients were administered by the intramuscular route (one ampoule) twice daily for one week. Both subjective and objective efficacy variables significantly improved in the combination drug group only, thus demonstrating the rationale for a combination therapy. Treatments were safe and well tolerated either at a local or systemic level.

Adrenochrome↗
PubMedDate not supplied

[Hemorrhoid ligation: a new technique].

The Author describes an old technique of hemorrhoids' treatment with a new disposable instrument: the canadian Patrick O'Regan's Ligator. On a series of 342 patients, from December 1998 to March 2000, the Author, treating this pathology with good results in percentage, stresses on the manageability and practicality of this instrument both in the hospital regimen and in the Day Hospital.

Hemorrhoids↗
PubMedDate not supplied

[Our experience in the treatment of hemorrhoids and circumferential mucosal rectal prolapse using Longo muco-prolapsectomy ].

The authors report their experience with the treatment of hemorrhoid disease and circumferential mucosal rectal prolapse with the use of a mechanical suturing device, according to the Longo technique. Over the period from March 98 to December 2000, 106 patients were treated with the above-mentioned procedure (100 patients for haemorrhoids and 6 for circumferential prolapse). Twenty-one patients had grade 4, 77 grade 3 and only 2 grade 2 disease. One hundred patients were followed up over a median period of 16.5 months (for the group with haemorrhoids) and 19 months (for the prolapse group). In 81% of cases the procedure was one-day surgery. Mucohaemorrhoidectomy with a stapler was well tolerated in terms of severity of postoperative symptomatology: in 42% of the patients operated on there was no need for any analgesic treatment. The time to return to work was 9.9 days for self-employed subjects and 15.6 days for the others. Refinement of the procedure and better patient selection may improve the results achieved with this technique. Stapled haemorrhoidectomy may be regarded as a sound technique that should be part of the surgeon's armamentarium. We suggest an "eclectic" approach whereby the stapling procedure may be included among the possible therapeutic options, with a view to optimising the choice of therapy for each individual patient.

Adult↗
PubMed2003

[Comparative aspects of surgical treatment of hemorrhoid].

Based on experience in treating 64 patients with chronic hemorrhoid a comparative clinical evaluation of efficiency of electrosurgical methods is carried out hemorrhoidectomy. Compared with traditional Milligan-Morgan surgery, electrosurgical method demonstrates the absence of intraoperative blood loss, a reduction in the algetic syndrome after surgery, a decrease in postoperative complications rates by 4.8 times. Physiological and physical activity, stool are also recovered by electrosurgery.

Adult↗
PubMed2003

[Surgery of hemorrhoids using the Long method and its complications].

BACKGROUND: The aim of this article is an assessment of new surgical procedure--stapled hemorroidectomy according to Longo. We do concentrate on surgical complications and possibilities of it's management. METHODS: Prospective, clinical follow up of patients in which stapled hemorrhoidectomy was performed during the period of 2 years (1st December 2000--30st November 2002). Observation concentrates on surgical complications of this method. All patients had a clinical check up 3 weeks and 3 months after surgery. In case of any problems treatment and follow up continues. RESULTS: Stapled hemorroidectomy was performed during the period of 2 years in 52 patients (100%). There was 11 patients (21.2%) with some of surgical complication. The most serious one was massive rectal bleeding after surgery, which has been observed in 4 patients (7.6%). Other surgical complications observed in our group were anal stenosis, local infection, acute anal fissure and retention of urine. CONCLUSION: Stapled hemorroidectomy is now one of feasible alternatives for surgical treatment of hemorrhoids. Serious surgical complications observed in our patients were bleeding from the stapled suture line and anal stenosis. The aim of this article is to refer possible surgical complications of this method, it's prevention and management.

Adult↗
PubMed2003

[Choice of hemorrhoidectomy method in chronic hemorrhoid].

Seventy patients with hemorrhoid of stage III-IV underwent surgery. In the study group (n = 21) hemorrhoidectomy was performed with ultrasonic knife. In control group 1 (n = 22) closed hemorrhoidectomy with recovery of anal canal mucosa was performed, in control group 2 (n = 27)--standard open hemorrhoidectomy with electrocoagulation. When ultrasonic knife was used, time of surgery reduced significantly compared with standard closed and opened hemorrhoidectomy--14.7 +/- 3.7, 40.2 +/- 6.5 and 32.5 +/- 5.6 min respectively (p < 0.05). On day 1 after surgery intensive pains were seen more rarely in patients of the study group compared with ones of both control groups (34, 75 and 66% patients respectively). In subsequent days intensive pains were seen also more rarely in study group than in control groups: on day 3 in 15, 40 and 35 patients, respectively, on day 7 in 5, 30 and 20 patients, respectively (p < 0.05). Degree of pain syndrome on day 1 after surgery in the study and control groups was 3.0 +/- 0.4, 7.0 +/- 0.2 and 6.0 +/- 0.3 points, respectively (p < 0.05). Patients of the study group demonstrated low requirement in narcotic and non-narcotic analgesics compared with the other groups. The time of postoperative rehabilitation of patients in the study and control groups was 12.3 +/- 2.4, 18.5 +/- 3.8 and 20.1 +/- 4.4 days, respectively (p < 0.05).

Adult↗
PubMed2003

[The use of Floseal in the prevention and treatment of intra- and post-operative hemorrhage in the surgical treatment of hemorrhoids and colporectocele. Preliminary results].

Stapled hemorrhoidectomy (PPH) is a modern approach to the treatment of hemorrhoids removing a circumferential strip of mucosa. In the same way the circumferential resection of the rectal prolapse (STARR) is successfully used for effective treatment of colporectocele and obstructed defecation syndrome. These surgical procedures offer several advantages over conventional techniques including reduced postoperative pain, stenosis and recurrences, an earlier recovery time and return to work. Furthermore, bleeding is one of the most common immediate complication (first week) and one of the possible late complication in these procedures. Our results with this surgery (153 PPH and 37 STARR) confirmed the data of many other Authors regarding the incidence of intra and early post-operative haemorrhages (1.3% in PPH and 2.7% in STARR). With the aim to reduce this complications, which represents the only negative side-effect of these procedures, we employed the FloSeal, a gelatine based haemostatic sealant with thrombin component, to control intraoperative bleeding. The preliminary results obtained in 10 PPH and in 7 STARR confirmed the theoretical usefulness of FloSeal in reducing this hemorrhagic complications.

Adult↗
PubMed1992

[Role of glomus shunts of the anorectal cavernous bodies in the mechanism of hemorrhoid development].

Histological examination of the hemorrhoids in 67 preparations of the rectum of adult persons showed the significance, in their development, of glomus and glomus blocking arteriovenous anorectal cavernous bodies, the two-three-fold increase of their volume was established. The dilatation of the glomus body lumen (from 20-30 to 270-480 microns) in the cavernous body wall is due to the epithelioid cell atrophy and sclerosis. When persistent dilatation and shortening of the distance between glomus mouths occurs, arterial blood passes from the peripheral branches of the superior rectal artery directly to the vena lumen, resulting, first, in the development of a simple compensatory and then varicose angioma-like flebectasia.

Adult↗