Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “CONCEPT FORMATION”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 415 records · Page 23Linked to original sources

Consistent contrast and correlation in free sorting.

Two experiments investigated free sorting, a type of unsupervised learning, with multiattribute drawings of alien animals. In previous research on concept formation, with simpler stimulus structure than ours, participants were insensitive to correlational structure in the stimuli, producing primarily "ID sorts," based on the values ofjust 1 dimension or attribute. Our experiments showed that participants used many strategies in categorizing but preferred to generate groupings that reflected the correlations in input when this did not violate consistent contrast. The second experiment used hierarchically structured stimuli to show that participants' sort strategies favor consistency within a set of contrasting categories, distinct from any preference for 1D sorting. Finally, both experiments show that correlational sorts are much more likely when the correlation-based sort contrasts consistently. Our data show complexity at work in free sort tasks: People are sensitive to multiple and sometimes conflicting biases for consistency and correlational structure in the category systems they create.

Humans↗

[Dimensions of personality disorders and neurophysiological correlates].

INTRODUCTION: To objective is to identify the factorial structure underlying personality disorders, using clinical and personality measures, and to check whether the resulting structure is valid and theoretically comprehensible, using neurocognitive and psychophysiological measures for establishing possible differences between the factors. METHOD: From the data obtained with the scales MCMI-II and BFQ administered to a sample of 87 subjects diagnosed as a case of any clinical category of DSM-IV personality disorders, and 17 normal controls, we carried out first-order and second-order factor analyses. RESULTS: Five first-order factors (designated as aggressive personality, personality with social deficit, non-pathological personality, obsessive personality and non-assertive personality) and three second-order factors (non-pathological/obsessive personality) were found. CONCLUSIONS: On studying the second-order factors in relation to neurocognitive and psychophysiological measures, it was found that socially-inhibited and non-assertive personalities (factor 1) are characterized by specific neuropsychological deficits in sustained attention; that aggressive personalities (factor 2) are characterized by impulsiveness and deficit in concepts formation; and that in non-pathological personalities with obsessive traits (factor 3), as obsessiveness increases, subjects present less efficacy in sustained attention tasks and greater psychogalvanic response to stress.

Adult↗

[P300 as a reflection of a mental set--P300 in the paradigm of Wisconsin Card Sorting Test].

We studied P300 at Pz in Wisconsin card sorting test (WCST) paradigm in 16 young normals. As it is well known that both the amplitude and the latency of P300 are affected by stimulus probability, we recorded P300 in the two different experimental conditions; in one condition we changed sorting category implicitly after every two successive correct responses of the subject (WCST2 condition), in the other condition we changed it tacitly after every five successive responses (WCST5 condition). In both conditions P300s were recorded following two types of feedback signals respectively; feedback signal of correct response (FC), and feedback signal of error response (FE). These experimental conditions were controlled by microcomputer. During the experiment the number of FCs and FEs were recorded, and frequencies of the feedback signals were calculated respectively. Analysis of variance revealed that P300s were more prolonged and more enlarged in FE than in FC significantly, and there is no difference between the two experimental conditions. The correlations between both the latency and the amplitude of P300s and frequency of feedback signals were low and not significant except between P300 amplitude and frequency of FE under WCST5 condition. This result shows that in WCST paradigm the main factor which affects the latency and amplitude of P300 is the meaning of the stimulus. Although WCST has been considered to be a test of concept formation, the subject must change or maintain his/her sorting category properly following the examiner's feedback declaration. From this point of view, WCST can be considered as a test of a mental set, in which FC demands maintaining a mental set and FE demands its change.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Neuropsychological outcome of pediatric liver transplantation.

Children with end-stage liver disease who undergo liver transplantation may have unrecognized neuropsychological and academic deficits, for which remediation programs may be available. Intellectual, academic, and neuropsychological measures of 28 pediatric patients who had received successful liver transplantation at least 1 year previously were compared with those of 18 patients with cystic fibrosis (to control for effects of growth retardation and chronic illness) matched for age, age at diagnosis, physical growth, and parents' socioeconomic status. Liver transplant patients had significantly lower scores on nonverbal intelligence tests (mean +/- SD for liver transplant vs cystic fibrosis patients: 89.1 +/- 19.1 vs 105.8 +/- 17.6), lower academic achievement, and lower zeta scores for age in the areas of learning and memory (-0.68 +/- 1.09 vs 0.19 +/- 1.24), abstraction and concept formation (-1.73 +/- 1.58 vs -0.79 +/- 1.37), visual-spatial function (-0.66 +/- 1.09 vs 0.10 +/- 0.69), and motor function (-0.13 +/- 0.85 vs 0.36 +/- 0.57). No differences were found on tests of verbal intelligence, or in alertness and concentration, perceptual-motor, and sensory-perceptual areas. Cyclosporine levels were found to correlate positively with motor speed (r = .41, P less than .05). Thorough psycho-educational and neuropsychological evaluations should be considered for pediatric patients who receive liver transplantation to allow these children to maximize their potential.

Adolescent↗

[Consciousness functions in psychoses. Concepts, empirism and hypotheses].

Schizophrenia may be described as a disease where speech, bodily language and social responsiveness are obvious expressions of a deteriorated ability to interact with the surroundings in a precise and relevant way. The lack of precision and relevance pertains to perception and recall as well as communication and action. The deficient potential for activation of the prefrontal cerebral cortex is a neurobiological correlate to the lesion of precise and relevant planning and expression. Impairment of formal thought and language in schizophrenia are suggested to result from a developmental disorder pertaining to language and concept formation (apperception). In reactive psychoses with dissociative disturbances of consciousness there is an inefficient capacity for adapting to external reality; thus relevant conscious planning and interaction with the outside world are impaired. Clinically a distractibility of a tematic nature ensues. Except for catastrophic events, psychotic reactions cannot be predicted from analysis of the actual experience--neither concerning the external nor the internal aspects of conscious awareness. Sometimes, however, previous events relating to the formation of the self may add explanatory value to the analysis of reactive psychosis. In some cases biological predisposition is the decisive determinant. The normal discrimination between sense-perception and imagination has a counterpart in the dichotomy of awareness of the outside world versus awareness of the self. The following are examples of psychotic experience where the normal ability for dichotomic discrimination may be damaged: Illusions of affect, hallucinations, Schneider's first rank symptoms, "Anwesenheit" and consciousness of time.(ABSTRACT TRUNCATED AT 250 WORDS)

Consciousness↗

[Microcomputer and rehabilitation of cognitive cerebral performance disorders].

Clinical neuropsychology has so far mostly been concerned with theoretical aspects of the brain-behavior relationship, as well as the diagnosis of cognitive deficits after brain damage. Only very recently has cognitive rehabilitation of the brain injured patient become a major area of interest in neuropsychology, and computer-assisted therapy of higher cortical functions is playing an increasing role especially in the United States. A survey found that 73% of the rehabilitation centers included were using computers in delivering their cognitive rehabilitation therapy, major areas of computer-assisted therapy being deficits of eye-hand coordination, attention, concentration, orientation, visual-spatial processing, memory, discrimination, problem solving, and concept formation. Treatment of speech disorders using computers is so far limited but will improve when more efficient language analyzers and synthesizers become available. More powerful microcomputers will lead to both computer-assisted and computer-managed cognitive programs, which allow for maximum flexibility and individualization of treatment. Computer use in cognitive rehabilitation should be subject to supervision by a therapist, and the following requirements should be met: 1) detailed diagnostic analysis of the differential cognitive performance pattern of a patient; 2) individual adaptation of computer peripherals to achieve optimum patient-computer-interaction; 3) selection and adaptation of therapy software to match the individual cognitive performance profile of a patient. Cognitive computer therapy appears to be most profitable in the rehabilitation phase and in post-rehabilitation treatment.

Brain Damage, Chronic↗

Neuropsychological outcome during late stage of recovery from brain injury: a proposal.

The neuropsychological outcome of Cranio-Cerebral Injury changes with time. This change may be best regarded as a specific effect/general effects ratio which lowers over time. The specific effects refer to disorders of information, recognition and symbolization. The present paper describes the general effects of brain injury. We will describe the lowered capacity of the cognitive system, which results in disorders of different aspects of concept formation and utilization (i.e. disorders of information processing).

Brain Injuries↗

Neuropsychological effects of marijuana.

This study assigned 81 non-naïve subjects, divided into low- and high-dose groups, to four experimental conditions (marijuana/marijuana, marijuana/placebo, placebo/marijuana and placebo/placebo) for two sessions separated by about one week. The low dose was 4.8 mg. Delta(9)-THC followed by 2.4 mg. one hour later. The high dose was 9.1 mg. followed by 4.5 mg. one hour later. A battery of neuropsychological tests was administered.The low dose produced generalized impairment of all mental processes (concept formation, memory, tactile form discrimination and motor function) and the effect was generalized to all modalities. The high dose resulted in more extensive impairment, again generalized.The drug effects noted were explained in terms of generalized impairment of central integrative processes. The effects of marijuana on learning as well as memory were explained in terms of impaired output (recall), but the impairment was transient.

Adult↗

Psychopathology of children with minimal brain injuries.

Children with the syndrome of minimal brain injuries, i.e. with psychic sequelae of a slight, diffuse lesion of the cerebral tissue, suffer from disorders of neural activity on different levels, from "primary disorders" such as of simple motor reactions and sensory defects to the most complicated performances such as speech and concept formation. It is assumed that mild lesions of the reticular formation of the brain stem is the common neurophysiological denominator of the whole syndrome. The psychopathological pictures, however, develop only from the continuous interaction of an organically conditioned state with unsuitable educational methods of the irritated parents and with other pathogenic factors of the external environment. The pictures can be divided into four basic diagnostic groups: behaviour disorders, neurotic manifestations, psychopathic traits, and psychotic manifestations.

Attention Deficit Disorder with Hyperactivity↗

Monitoring neurotoxins in industry: development of a neurobehavioral test battery.

To facilitate the early detection of neurotoxicity in workers exposed to hazardous substances, we assembled a set of noninvasive neurobehavioral tests designed to assess memory, verbal concept formation, visuomotor performance, and mood. The tests were administered to an unexposed reference population and multivariate prediction equations were developed to control for effects of age, gender, and education. To define the briefest test set with appropriate sensitivity and specificity, we applied factor analysis and stepwise logistic regression to data from our referents and a group of lead-exposed workers. As a result, we have identified a comprehensive set of tests that can be administered in less than 40 minutes by trained medical technicians on plant premises and used to detect the early effects of neurotoxic substances on exposed workers. Guidelines for applying this technique to common work-place exposures, including other metals and organic solvents, are discussed.

Emotions↗

The eye of the very young beholder: sex typing of infants by young children.

This study was designed to examine the effects of gender labeling on young children by determining the extent to which the qualities they attribute to an infant depend on whether that infant is identified as a girl or as a boy. 20 boys and 20 girls from each of 3- and 5-year-old age groups were shown a 5-min videotape of a boy and a girl infant engaged in a variety of activities. One of the infants was labeled a "boy" and the other a "girl", with the labels reversed for half of the subjects. Each child was then asked to respond to a series of 12 bipolar adjectives, 9 representing sex-stereotypic dimensions, in a forced-choice manner. The major findings indicate that both 3- and 5-year-old children responded in a significantly stereotypic manner based on the gender labels provided for the infants, regardless of the infant's actual gender. A simple concept-formation paradigm is proposed to account for these findings.

Child Behavior↗

Primitive defenses: cognitive aspects and therapeutic handling.

A discussion of "Primitive Defenses: cognitive Aspects and Therapeutic Handling," by Leslie S. Groh, Ph.D. One of Dr. Groh's explicit aims in this interesting and thought-provoking paper is to show that Melanic Klein's concept of schizoid mechanisms is therapeutically applicable by a psychologist. This aim he does indeed achieve, using very interesting and convincing clinical examples. However, his other aim, to provide evidence in support of Piaget's view that only at about nine months of age is abstract concept formation possible, is definitely not proven. Actually, he offers additional clinical support to the claim of Klein's followers that adult psychoses are accessible to the interpretive, psychoanalytic approach. This suggests that Klein's dating of the onset of mental mechanisms should not be lightly dismissed because observational methods do not reveal what is perceived by the psychoanalytic method.

Adolescent↗

[Clonal study of hematopoietic cells].

Clonal analyses using X-chromosome inactivation patterns of the phosphoglycerate kinase (PGK) and DXS255 (M27 beta) genes were performed in women with various hematological diseases or normal hematopoiesis. Four (17%) of 24 hematologically normal females had a skewed Lyonization pattern. It, however, appeared that in the majority of cases clonality determination of myeloid cells would be possible in comparison with lymphocytes. Blasts of acute myeloid leukemia (AML) (21) and granulocytes and bone marrow cells of chronic myeloproliferative disorders (6) were all shown to be clonal, suggesting that this method was useful for the concept formation of a clonal disorder. Twelve of 14 patients with the myelodysplastic syndromes had a clonal pattern and 8 of 10 patients with aplastic anemia had a polyclonal pattern. Three of 34 patients with AML during remission were diagnosed as a clonal hematopoiesis and associated with features of myelodysplasia during remission, when clonal patterns are different in patients with the same disease, it seems important to elucidate their clinical implications.

Clone Cells↗

[Inductive versus associative processes in stimulus discrimination].

The experiment reported here was an attempt to demonstrate that the solution of specific discrimination problems is based on rules rather than on differences in associative strengths. With positive and negative patterning as examples, we examined whether or not the solution of the discrimination problem depends on the number of reinforcements for each individual stimulus when the total number of reinforcements is kept constant. This was achieved by manipulating the number of stimuli used. We also examined the transfer to new stimuli. Forty subjects took part in a 2 x 2-factorial experiment with anticipatory skin conductance responses as the dependent variable. All the results were in accordance with the assumption of rule based problem solution. The amount of discrimination was independent of the number of reinforcements for each stimulus. Furthermore, according to results of concept formation studies, an asymmetry in transferring the solution to new stimuli was observed.

Adult↗

Effect of Alzheimer's disease on communication function.

Dementia has a significant impact on communication abilities. The profile of communication skills in dementia differ from the profiles of developmental aging and focal organic disorders. Normal elders may have some episodic memory losses and slower reaction times as aging progresses. Focal language disorders (aphasia and right hemisphere disorders) will affect specific language functions without affecting intellect and memory. Communication in the presence of dementia progresses through three stages. The first stage deficits are primarily in the content area of lexical access and subtle conversational skills. The second stage reveals increased difficulty in content areas including concept formation, lexical access diminished graphic abilities, reliance on syntactic abilities and reduced memory function. The third stage of dementia may involve all of the above to a more severe degree, with severe memory and intellectual deficits. Assessment batteries have been developed to evaluate the deficit areas frequently associated with communication in dementia. Clinical evaluation and standardized assessment can differentiate the language profile of dementia from other neurological disorders. Therapeutic intervention in communication focuses on maintaining the patient's communication and providing educational information for caregivers for more effective communication strategies.

Alzheimer Disease↗

Concepts of seroma formation and prevention in breast cancer surgery.

BACKGROUND: Seroma formation is the commonest early sequel to breast cancer surgery especially when axillary dissection is undertaken. It is associated with significant morbidity and financial burden. The main pathophysiology of seroma is still poorly understood and remains controversial. The optimal ways to reduce the incidence of seroma formation are unknown. The aim of this paper is to review the concepts of pathophysiology of seroma formation following mastectomy and breast-conserving surgery for cancer. The various techniques in practice to reduce its incidence and treatment are outlined. METHOD: MEDLINE search of published work on the subject with respect to its pathophysiology, prevention and treatment was carried out. Manual retrieval of relevant articles in the reference lists of the original papers from the MEDLINE was then carried out. RESULT: The pathophysiology and mechanism of seroma formation in breast cancer surgery remains controversial and not fully understood. Methods of prevention and treatment of seroma remain varied and inconclusive. CONCLUSION: Evidence suggests an increase in the incidence of seroma because of thermal trauma from electrocautery dissection, but this is indispensable for surgical haemostasis. Obliteration of dead space by various flap apposition techniques has been shown to be advantageous in reducing incidence and volume of seroma. Low-pressure suction drainage reduces seroma volume and duration of drainage leading to earlier drain removal. Preventive measures have to be tailored according to individual patient and operative factors.

Antineoplastic Agents, Hormonal↗

Formation of the sameness-difference concept by Japanese monkeys from a small number of color stimuli.

Japanese monkeys were trained to form the sameness-difference concept. In Experiment 1, four monkeys were trained with two colors to discriminate matching stimulus pairs from nonmatching pairs by reinforcing only lever-pressing responses to matching pairs with a variable-interval schedule. Three monkeys showed successful transfer of this discrimination to two new colors, thus demonstrating that some Japanese monkeys are able to form this relational concept from a minimum number of stimuli. In Experiment 2, two monkeys were trained, in a Yes/No procedure with three colors, to press one lever under matching pairs and another lever under nonmatching pairs. Poor transfer performances to three new colors suggest that simultaneously establishing two different response patterns to matching and nonmatching pairs is ineffective in forming the concept. In Experiment 3, the amount of transfer to three new colors after mastering a standard three-color matching-to-sample task was compared with that of a modified task in which correct responses were reinforced with a within-trial variable-interval schedule. All three monkeys showed greater transfer with the modified procedure. The results suggest that the variable-interval schedule adopted within trials is effective in forming the sameness-difference concept.

Animals↗