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Growth rate and anthropometry of a Libyan population.

Body weight, standing height, skin-fold thicknesses at four sites (biceps, triceps, subscapular, and suprailiac) and percent fat were measured in 1800 Libyan children and adults aged 6-25 years. There was a marked difference in anthropometric measurements between boys and girls at the age of 14 years. Libyan children have the same rate of increase in standing height as European children. Percentage fat was correlated significantly (P less than 0.05) with body mass index. Percentage fat in girls was twice that in boys during all stages of growth. The present study can be used as a source of reference for a Libyan population.

Adipose Tissue↗

Detecting malnutrition at age 6-12 months: international comparisons of arm circumference v. standard anthropometry.

Growth faltering, which may herald protein-energy malnutrition (PEM) usually begins between ages 6 and 12 months. However, arm circumference (AC or MUAC) has mainly been used to screen for PEM between 12 and 60 months of age, when AC is age-independent. This study of 378 infants aged 6-12 months in Pakistan, Nepal, Sierra Leone, and Papua New Guinea showed that a cut-off 12.5 cm AC selects infants < 80 per cent weight-for-age (WA) with 76 per cent sensitivity and 90 per cent specificity. Of the 378 infants studied 131 (35 per cent) had WA < 80 per cent and 126 (33 per cent) had AC < 12.5 cm. Weight-for-length agreed less well with AC. The inter-regional prevalence range of AC < 12.5 cm was 29-40 per cent, while the WA < 80 per cent range was 27-45 per cent. When AC is plotted against age, a flat 'plateau' (slope = 0.04) shows age-independence between 6 and 12 months in these 378; this contrasts to the 10 per cent AC increase in European reference populations. Because this AC plateau parallels the WA plateau seen between 6 and 12 months of age in most developing nations, AC < 12.5 cm may provide a simple and valid screening test for early PEM in this crucial age bracket. Conformatory studies elsewhere are indicated.

Anthropometry↗

Nutritional anthropometry--validity of cut-off points.

The present communication seeks to describe an alternate approach of arriving at cut-off levels using ratio of percentiles for (i) differentiating normal children from the undernourished ones, and (ii) identifying the severely undernourished group of children in the community on the basis of body weight and height. It also examines validity of the cut-off levels presently used of weight for age (Gomez and Indian Academy of Paediatrics classification) and height for age parameters. 1. The cut-off levels are independent of the reference standard and, as such, the same cut-off levels could be used irrespective of the standards. 2. It is desirable to have separate cut-off levels for preschool and school age groups. The use of common cut-off points for both the age groups seems to result in loss of sensitivity of the order of over 5 per cent. 3. The use of the 90 per cent cut-off level in the Gomez classification misclassifies some of the normals as undernourished, thereby tending to overestimate the problem of undernutrition in communities. 4. The body weight groups based on the suggested cut-off points do bear a relationship to the prevalence of signs of PEM--the greater the weight deficit, the higher the prevalence of signs of PEM in preschool children.

Anthropometry↗

Maternal anthropometry as predictors of low birth weight.

The usefulness of maternal anthropometric parameters i.e. maternal weight (MWt), maternal height (MHt), maternal mid-arm circumference (MMAC) and maternal body mass index (MBMI) as predictors of low birth weight (LBW) was studied in 395 singleton pregnancies. The maternal anthropometric parameters were measured in the first trimester of pregnancy and were plotted against the birth weight of the newborns. Significant positive correlations were observed among MWt and birth weight (r=0.38), MHt and birth weight (r=0.25), MMAC and birth weight (r=0.30) and MBMI and birth weight (r=0.30). The most sensitive being MWt (t=7.796), followed by MMAC (t=5.759), MHt (t=4.706) and MBMI (t=5.89). For prediction of LBW, the critical limits of MWt, MHt, MMAC and MBMI were 45 kg, 152 cm, 22.5 cm, 20 kg/m2 respectively. From these observations, the use of colour-coded weighing machines, height rods and tapes may be devised for use by peripheral health workers and traditional birth attendants for detection of mothers at risk of delivering low birth weight babies (Table 5). Mothers who have anthropometric parameters in the 'red zone' are at risk of delivery LBW infants.

Anthropometry↗

Lead contamination and anthropometry of the newborn baby.

The objective of the present study was to determine the lead (Pb) concentration in umbilical cord blood and its relationship with anthropometric measurements of 55 newborns. Umbilical cord blood was collected immediately after delivery for the determination of Pb and hemoglobin (Hb) concentrations. Hb was measured with the HemoCue system and blood Pb concentration was determined by graphite furnace atomic absorption spectrophotometry. We observed an inversely proportional correlation of cord blood Pb concentrations with newborn weight (beta=-0.275; p=0.048) and length (beta=-0.460; p=0.003). The mechanisms whereby Pb reduces newborn size are unknown. One possible explanation would be a reduction in fetal thyroid hormones caused by the presence of Pb. However, further studies are necessary to confirm this hypothesis.

Anthropometry↗

Effect of gender, age, and anthropometry on axial and appendicular muscle strength.

OBJECTIVE: To assess age and gender differences in muscle strength. DESIGN: The strength of back extensors, upper limbs (grip), and lower limbs (knee extensors) was measured. Anthropometric measurements and body mass index also were assessed. RESULTS: Group comparisons were made for each decade. Back extensor strength (BES) in subjects aged 20 to 89 yr ranged from 93 to 832 N in men and from 71 to 440 N in women. BES peaked in the fourth decade for men and in the fifth decade for women. When the two genders were compared, muscle strength in women was less than that in men at all ages. At different decades, women's BES ranged from 54% to 76% compared with that of men's BES. There was a 64% loss of BES in men from the peak in their fourth decade (556 N) to the lowest level in their ninth decade (201 N). Women experienced a 50.4% loss from the peak in their fifth decade (306 N) to the lowest level in their ninth decade (152 N). CONCLUSIONS: Men had a greater loss of BES than women with increasing age. In both genders, there was more loss of BES than appendicular muscle strength. Reduction in BES in women coincided with increased body mass index in older age. In women, there was a negative correlation between body weight and level of physical activity, whereas this finding was not evident in men. Background factors related to a higher incidence of back pain, falls, and fractures, especially in women, may be a reduction in muscle strength, along with increasing age and body mass index. This cross-sectional study showed that physiologic reduction of muscle strength, which began early in life, later stopped and that muscle strength even improved, despite the aging process. Therefore, initiating strengthening exercises at any age is encouraged to prevent the impact of several age-related musculoskeletal challenges.

Adult↗

Relationships of blood pressure to fibrinolysis: influence of anthropometry, metabolic profile and behavioural variables.

OBJECTIVE: To investigate the relationship between blood pressure and the plasma fibrinolytic system and to verify whether this association was independent or mediated by one or more potential confounding factor. DESIGN: A random sample of 94 males aged 38 years subdivided into normotensives, hypertensives and those hypertensives with the highest blood pressure values. METHODS: Overall and regional obesity, blood lipids, fasting and 2-h post-load glucose, C-peptide and insulin levels, and main behavioural variables, including adipose tissue fatty acid composition (an objective index of dietary fat intake), were measured. The plasma fibrinolytic system was evaluated by determining activities and total plasma concentrations of both tissue-type plasminogen activator before and after venous occlusion, and its inhibitor plasminogen activator inhibitor type-1 (PAI-1). RESULTS: PAI-1 activity was significantly higher in the hypertensives than in the normotensives. PAI-1 antigen tended to parallel PAI-1 activity, and levels of tissue-type plasminogen activator antigen and activity tended to be lower in the hypertensives at baseline and after venous occlusion, but not significantly different from those in the normotensives. The hypertensives also had significantly higher body mass index and body fat content (measured by bio-impedance), increased plasma triglycerides, uric acid, fasting and 2-h glucose, C-peptide and insulin concentrations. In univariate linear regression analysis both systolic and diastolic blood pressures were found to be positively correlated with PAI-1 levels (r = 0.27, P < 0.01, for both). This correlation was maintained after adjustment for total body fat, fasting glucose, fasting insulin concentration or adipose tissue alpha-linolenic acid; however, it was no longer significant after adjustment for plasma 2-h insulin, 2-h C-peptide, 2-h glucose or triglyceride levels. Multivariate regression analysis revealed that only 2-h insulin and triglyceride concentration showed an independent association with PAI-1 levels. CONCLUSIONS: This study confirms that, in 38-year-old males, hypertension is associated with increased PAI-1 activity. It supports the possibility that the relationship between blood pressure and PAI-1 may reflect the overall effect of the insulin resistance syndrome (in particular hyperinsulinaemia and hypertriglyceridaemia) rather than a direct effect of blood pressure on the fibrinolytic system.

Adult↗

Intima-media thickness and diameter of carotid and femoral arteries in children, adolescents and adults from the Stanislas cohort: effect of age, sex, anthropometry and blood pressure.

OBJECTIVES: To study carotid and femoral intima-media thicknesses and diameters in relation to age, sex, morphologic status and blood pressure. PARTICIPANTS: The subjects were 369 men and women (aged 10-54 years) from the Stanislas cohort, with no known cardiovascular disease. METHODS: Intima-media thicknesses and diameters were measured by B-mode ultrasonography. The effects of sex, age, smoking, anthropometric variables, cholesterol and blood pressure were studied using bivariate and regression analysis. RESULTS: Carotid and femoral intima-media thicknesses were not affected by age nor by sex up to 18 years of age. Thereafter, they increased sharply in men and remained higher than in women. Values were correlated with systolic blood pressure only in men, and with fat-free mass in children and young adults only at the femoral site. Smoking, body mass index and fat mass were associated with intima-media thicknesses only in adults. Carotid diameter was little affected by age during childhood and in adults. Femoral diameter increased up to the age of 18 in both sexes and remained unaffected by age thereafter. This increase was more pronounced in boys, and so values became consistently greater in males aged over 14 years. Carotid diameter was correlated with body mass index or fat mass whereas femoral diameter was correlated with weight or fat-free-mass in children and men. The opposite was observed in women. CONCLUSION: Sex differences occur before adolescence for arterial diameter, but only at an adult age for intima-media thickness. In young subjects, carotid geometry seems to be influenced by blood pressure and excess body weight, while femoral artery geometry seems to be related to blood pressure and body growth.

Adolescent↗

Assessment of nutritional status and body composition in children using physical anthropometry and bioelectrical impedance: influence of diurnal variations.

BACKGROUND: To observe whether there are diurnal variations when assessing children's body composition, using physical anthropometric and bioelectrical impedance (BI) methods. METHODS: In 32 children (18 females and 14 males) aged between 7.1 and 14.9 years, weight, height, arm circumference (AC), four skinfolds, and total body impedance (Z) were measured at 8 A.M., 12 noon, 4 P.M., and 8 P.M. on the same day. Body mass index (BMI), skinfolds sum (SS), total body water (TBW), fat-free mass (FFM), and fat mass (FM) were also calculated at these times. RESULTS: Height at 8 P.M. was 1.156 +/- 0.54 cm less than at 8 A.M. (P < 0.001) and BMI increased 0.434 +/- 0.29 kg/m2 at 8 P.M. (P < 0.001). Weight, SS and AC underwent no significant changes in the course of the day. Z was 5.83% less at 8 P.M. than at 8 A.M. (P < 0.001), yielding a TBW and FFM increase at 8 P.M. of 0.855 +/- 1.061 and 1.173 +/- 1.47 kg, respectively (P < 0.001). CONCLUSIONS: In children there is a diurnal decrease in height, impedance and FM, and an increase in BMI, TBW, and FFM. These factors must be taken into account when using such methods for assessing nutritional status in childhood.

Adipose Tissue↗

Immunoreactive ghrelin in human cord blood: relation to anthropometry, leptin, and growth hormone.

BACKGROUND: Ghrelin is secreted by the stomach, the hypothalamus, and the placenta in humans and has growth hormone-secreting and orexigenic properties. Leptin is secreted mainly by the adipocyte, plays a major role in energy balance, and reflects fat mass in infants as well as adults. Leptin and ghrelin central effects are mediated, at least partly, through the neuropeptide Y/Y1 receptor pathway in the hypothalamus. METHODS: We determined whether ghrelin is also present in the fetus and investigated its relationship to leptin, growth hormone, birth weight, and calf and abdominal circumferences in 90 full-term neonates. RESULTS: Immunoreactive ghrelin was detected in all cord samples (mean +/- SD, 187 +/- 88 pmol/L; range, 66-594 pmol/L). In contrast to leptin, ghrelin concentrations of boys and girls were not statistically different. In female neonates, ghrelin is inversely correlated with anthropometric measures. In male neonates, ghrelin is positively correlated with leptin and negatively with growth hormone. CONCLUSION: The presence of significant ghrelin concentrations in all neonates before the first feeding is intriguing. Unlike the fairly constant concentrations and effects of leptin over the short term, the wide variability of ghrelin concentrations observed in newborns raises the possibility that ghrelin secretion causes short-term changes in feeding behavior. We suggest that ghrelin may play a physiologic role in the initiation of feeding.

Abdomen↗

Anthropometry and bioelectrical impedance inconsistently predicts fatness in women with regional adiposity.

PURPOSE: This investigation examined the accuracy of several generalizable anthropometric (ANTHRO) and bioelectrical impedance (BIA) regression equations to estimate % body fat (%BF) in women with either upper body (UB) or lower body (LB) fat distribution patterns. METHODS: Thirty-six premenopausal women were individually matched for age (X = 38.6 +/- 6.6 yr), BMI (X = 25.5 +/- 4.2 kg x m(-2)) and %BF (30.3 +/- 8.1%; hydrostatic, [UWW]) and placed by waist to hip ratio (WHR) into two distinct groups: LB (N = 18; WHR < or = 0.73) and UB (N = 18; WHR > or = 0.80). Equations tested were ANTHRO: Jackson et al. (JPW-7 and 3 site), 1980; Durnin and Womersley (DW), 1974; Tran and Weltman (TW), 1989; and Vogel et al. (V), 1988; BIA: Lohman (L), 1992; Gray et al. (G), 1989; and VanLoan and Mayclin (VLM), 1987. Circumference and skinfold measures were made by a trained technician. BIA (Vallhalla, 1990B) measures were taken 4 h postprandially under controlled conditions of water intake and exercise. %BF by UWW (criterion) was not different between groups (UB = 30.8 +/- 8.2%; LB = 29.7 +/- 8%). RESULTS: In the UB group, three of five ANTHRO equations significantly overestimated %BF by approximately 6% (range = 3-8%) as compared with UWW. BIA overestimated %BF in UB by 5% using G and in both groups by about 6% using VLM, whereas L underestimated %BF in LB by about 4%. CONCLUSION: We conclude that ANTHRO and some BIA equations are accurate for predicting %BF in LB fat "shaped" women but are not appropriate for women with primarily abdominal fat patterning.

Adipose Tissue↗