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At least 397 records · Page 22Linked to original sources
PubMed2004

A case of fatal respiratory failure after surgery for advanced supraglottic laryngeal carcinoma.

Pulmonary lymphangitic carcinomatosis (PLC) is an uncommon type of pulmonary metastasis from laryngeal carcinoma. We encountered a case of fatal respiratory failure after surgery for supraglottic laryngeal carcinoma with multiple cervical lymph node metastases. On day 25 postoperatively, the patient suddenly developed fever and noted slowly progressive difficulty in breathing. Laboratory data, radiological findings, and the clinical course of this patient were strongly suggestive of PLC. The patient refused fiberoptic bronchoscopy and glucocorticoid therapy, leading to rapid deterioration due to increasing respiratory distress, and died of respiratory failure on postoperative day 32. PLC should be considered a possible presentation of pulmonary metastasis associated with head and neck carcinoma. Chest CT may be needed to detect subclinical PLC, especially in cases of advanced head and neck carcinomas.

Aged↗
PubMed1998

Stridor as a manifestation of supraglottic carcinoma in a patient with AIDS.

As patients with human immunodeficiency virus (HIV) infection are living longer, the differential diagnosis of stridor in acquired immunodeficiency syndrome (AIDS) patients should be broadened to include malignancies in addition to the common causes of infections and functional airway abnormalities. Herein, we describe a 50-year-old woman with AIDS who presented with stridor secondary to supraglottic squamous cell carcinoma.

Carcinoma, Squamous Cell↗
PubMed2006

Mumps virus infection in adults: three cases of supraglottic edema.

Mumps virus infections primarily involve the parotid glands and most frequently affect school-aged children. We present three unusual adult cases of mumps with dyspnea secondary to severe swelling of the salivary glands and review previously reported cases in the literature. Dyspnea developed progressively after the onset of salivary gland swelling. Laryngoscopy revealed an advanced edematous change in the supraglottis obstructing the airway. In two cases, tracheotomy was needed because of rapid worsening of the supraglottic edema. Questioning regarding breathing problems and laryngoscopic examination is therefore recommended when one encounters a mumps case with combined parotid and salivary gland swelling.

Adult↗
PubMed1978

Primary oat-cell carcinoma of the larynx following supraglottic laryngectomy for squamous-cell carcinoma.

An extremely rare case is reported of a primary oat-cell carcinoma of the larynx in a 70-year-old man who had been treated eight years previously for squamous-cell carcinoma of the larynx by means of supraglottic laryngectomy. A review of the literature revealed only 5 unequivocal previous reports of this primary oat-cell tumor; the present report makes a total of 6 cases. The morphologic pattern, histogenesis and biologic behavior are discussed. The patient of this report was treated by surgical intervention and radiotherapy. He was well, six months later. Only one of the 5 patients previously reported survived for more than a few months. This type of lesion has a poor prognosis because of its tendency to metastasize early to various organs.

Aged↗
PubMed1995

The supraglottal articulation of prominence in English: linguistic stress as localized hyperarticulation.

The results of an articulatory investigation of the supraglottal correlates of linguistic prominence in English, and a proposal of a unified description of linguistic stress are reported. Three models of stress are evaluated: that prominence expands jaw movement, that stress expands an abstract articulatory scale involving the opening and closing of the vocal tract, and that stress involves a localized shift toward hyperarticulate speech. A corpus of x-ray microbeam records of sensible speech is studied, within which the stress pattern is controlled and is checked by means of an intonational analysis. Jaw movement data yield similar results to earlier studies, but kinematic differences interpreted with reference to a gestural theory suggest that different subjects use different articulatory strategies to articulate stress contrasts. In addition, the jaw, lip, and tongue interact in the articulation of stress in subject dependent ways. Thus the articulation of stress should be formulated in terms of abstract articulatory goals, rather than in terms of individual articulator positioning. Finally, the data show that stress affects the articulation of nonsonority distinctions such as backness in vowels and point of articulation in consonants. A hyperarticulation model of stress is discussed in terms of these results.

Humans↗
PubMed1998

Adult supraglottitis: an important cause of airway obstruction.

Supraglottitis in the adult can progress rapidly to complete airway obstruction. Successful management requires a high index of clinical suspicion at initial presentation and anticipation of a fulminant course. All cases should be assessed in a resuscitation area by senior medical staff.

Aged↗
PubMed2001

Spontaneous supraglottic haemorrhage in a patient receiving warfarin sodium treatment.

A case of spontaneous, isolated supraglottic haemorrhage in a patient recently started with warfarin sodium treatment is described. The symptoms of sore throat, dysphonia, stridor, dysphagia or a neck swelling in a patient taking anticoagulants should alert the clinician to the possibility of this rare but potentially fatal complication.

Anticoagulants↗
PubMed1979

Low-dose preoperative radiation therapy in carcinoma of the supraglottic larynx.

Seventy patients treated for all stages of carcinoma of the supraglottic larynx were analyzed retrospectively. A preoperative dose of 3,000--3,600 rads was given in 15 to 18 treatments over three to four weeks and surgery carried out four weeks later. The 5-year disease-free survival rates were approximately 75% in patients with early disease and 50% in those with more advanced disease. Survival with early disease was similar to that achieved by radical radiotherapy alone, while survival with advanced disease was similar to that achieved by surgery alone. These results suggest that low-dose preoperative irradiation is of limited value.

Aged↗
PubMed1996

Supraglottic airway pressure-flow relationships during oronasal airflow partitioning in dogs.

We studied pressure-flow relationships in the supraglottic airway of eight prone mouth-open anesthetized (intravenous chloralose or pentobarbital sodium) crossbred dogs (weight 15-26 kg) during increasing respiratory drive (CO2 administration; n = 4) and during graded-voltage electrical stimulation (SV; n = 4) of the soft palate muscles. During increased respiratory drive, inspiratory airflow occurred via both the nose (Vn) and mouth (Vm), with the ratio of Vn to Vm [%(Vn/Vm)] decreasing maximally from 16.0 +/- 7.0 (SD) to 2.4 +/- 1.6% (P < 0.05). Simultaneously, oral airway resistance at peak inspiratory flow decreased from 2.1 +/- 1.0 to 0.4 +/- 0.4 cmH2O (P < 0.05), whereas nasal airway resistance did not change (14.4 +/- 7.2 to 13.1 +/- 5.4 cmH2O; P = 0.29). Inspiratory pressure-flow plots of the oral airway were inversely curvilinear or more complex in nature. Nasal pathway plots, however, demonstrated a positive linear relationship in all animals (r = 0.87 +/- 0.11; all P < 0.001). During electrical stimulation of soft palate muscle contraction accompanied by graded constant-inspiratory airflows of 45-385 ml/s through an isolated upper airway, %(Vn/Vm) decreased from 69 +/- 50 to 10 +/- 13% at a SV of 84 +/- 3% of maximal SV (P < 0.001). At a SV of 85 +/- 1% of maximum, normalized oral airway resistance (expressed as percent baseline) fell to 5 +/- 3%, whereas normalized nasal resistance was 80 +/- 9% (both P < 0.03). Thus control of oronasal airflow partitioning in dogs appears mediated more by alterations in oral route geometry than by closure of the nasopharyngeal airway.

Air Pressure↗
PubMed1987

Paraganglioma of the supraglottic larynx.

Supraglottic paraganglioma is described in an 80-year-old woman who presented with a small shiny-red mass at the posterior aspect of the left aryepiglottic fold. Histological examination revealed the typical 'zellballen' pattern of extra-adrenal paragangliomas. The tumor was locally excised and did not recur at 24 months follow-up.

Aged↗
PubMed2005

Penetrating foreign body mimicking supraglottic carcinoma.

Penetrating trauma to the neck is a rare observation. We report the first case of laryngeal myofibroblastic tumor due to a persistent splinter of glass in the preepiglottic space, which presented with recurrent mild hemoptysis and cough, and mimicked supraglottic carcinoma. The clinical and imaging evaluations are herein reported. Finally, medical and surgical options in the management of this unusual observation are discussed.

Aged↗
PubMedDate not supplied

Evaluation of randomized preoperative and postoperative radiation therapy for supraglottic carcinoma. Preliminary report.

One hundred and ten patients with supraglottic squamous cell carcinoma have been randomized for preoperative radiation therapy and surgery versus surgery and postoperative radiation therapy. Data have been analyzed on 94 patients in this preliminary report. The differences between the two groups with respect to local control and survival are not statistically significant at this time. Additional accrual and continued follow-up are necessary in order to make a more definite treatment comparison.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

Repair of supraglottic laryngeal stenosis with postcricoid involvement. A case report.

A supraglottic stenosis with postcricoid stenosis was successfully corrected in a single stage procedure by excising the scar tissue and the arytenoid cartilage and the use of mucosal flaps to recover the right side of the larynx and postcricoid area. By obtaining good mucosal approximation without tension the need for a free skin graft or mucosal graft was avoided.

Adult↗
PubMedDate not supplied

Factors in successful deglutition following supraglottic laryngeal surgery.

Aspiration is the major problem in deglutition associated with conservation laryngeal surgery. Closure of the glottic sphincter, depression of the epiglottis over the laryngeal inlet, elevation of the thyrohyoid complex under cover of the base of the tongue and appropriate relaxation of the cricopharyngeal muscle to permit unobstructed passage of food into the esophagus are important mechanisms that prevent food from entering the trachea. Partial laryngeal surgery can interfere with one or a combination of these mechanisms. Analysis of the records of all evaluable patients who underwent horizontal supraglottic resections from January 1976 to June 1981 was undertaken. The incidence of deglutition problems is reported. In addition, the effects of resection or preservation of the hyoid, arytenoid, base of tongue and branches of the vagus and the effect of cricopharyngeal myotomy upon ultimate swallowing function are analyzed.

Adult↗
PubMedDate not supplied

Supraglottitis and Hemophilus parainfluenzae: pathogenic potential of the organism.

Hemophilus parainfluenzae may be a normal inhabitant of the pharynx, but it can have pathogenic potential elsewhere in the body. It has been identified as a cause of bacteremia and meningitis. The case discussed here represents the first report of H parainfluenzae-induced supraglottitis in a child. In reviewing its pathogenic potential in the upper respiratory tract, it appears that its major effect could be the ability to transfer ampicillin resistance to ampicillin-susceptible Hemophilus influenzae.

Acute Disease↗
PubMedDate not supplied

Statistical correlations among supraglottic cancers.

The purpose of this study was to quantify the extent to which the presence or absence of cancer in endoscopically evaluable regions of the supraglottic larynx predicted occurrence in a region less easy to visualize but of critical importance to the nature of treatment. Histologic findings from 32 specimens were subjected to two separate statistical analyses. In the first analysis, the presence of cancer on the floor of the ventricle was the best predictor of tumor below this level. The combination of variables with the best correlation was cancer on the floor of the ventricle and in the vestibular folds. In the second analysis, involvements of the deep structures in the aryepiglottic folds and in the infrahyoid epiglottis were the only significant predictors of tumor extending to the preepiglottic space. The results suggest that such statistical analyses may provide guidelines for selection of treatment.

Glottis↗