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Results for “Splenic Neoplasms”

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[Intrasplenic metastasis of malignant ovarian tumor: clinical analysis of 12 cases].

Intrasplenic metastasis of ovarian malignancies are uncommon. From 1986 to 1992 only 12 such cases were diagnosed, being 1.2% of the total number of patients with ovarian malignancies treated in tumor hospital during the same period. Of the 12 metastasis, 6 were poorly differentiated. Diagnosis was made through imaging techniques or surgery. The median interval from the diagnosis of the primary disease to intrasplenic involvement was 28 months. The metastatic lesions, presented themselves as single or multiple nodes within the cortex of the spleen. Clinical features were not remarkable. It was thought that the occurrence of intrasplenic involvement might be due to greater tumor bulk, poor differentiation and decreased host immuno-competence caused by chemotherapy. Most of the intrasplenic metastasis was found after liver metastasis or simultaneously with the latter. The main route of the tumor spread might be via blood vessels. Sole intrasplenic metastasis can be treated by surgery with a temporarily good result. Poor prognosis and high mortality characterize intrasplenic metastasis. The median survival was only 7 months.

Adult↗

[Kasabach-Merritt syndrome].

Kasabach Merritt syndrome, first recognized in 1940, is characterized by haemangiomatosis, thrombocytopenia and intravascular coagulation. It is most often seen in children, rarely in adults. The mortality rate is 20-30%. Treatment is by removing the haemangiomatosis and correcting the consumptive coagulopathy. The purpose of this paper is to present a patient with Kasabach Merritt syndrome with haemangiomatosis in the spleen and the liver. A review of the relevant literature is given.

Adult↗

Primary splenic lymphoma presenting as a large cyst.

An atypical case of splenic lymphoma is presented. A large cystic mass lesion in the splenic area was found in an 80-year-old man. He was involved in a traffic accident, and subsequently the cyst ruptured. The histological diagnosis of malignant lymphoma was made at emergency splenectomy. No other lesions were identified, and there were no signs of tumor recurrence four months after the operation.

Aged↗

[Case report of spontaneous splenic rupture in splenoma].

We report one case of splenoma, a rare benign tumor of the spleen. Initial symptoms were repeated attacks of tail pancreatitis, that led to splenectomy for spontaneous splenic rupture. Splenomas may be asymptomatic or cause haematologic symptoms. Recently their association with neoplastic and haematologic disorders has been emphasized. Therefore such diseases must be ruled out when a splenoma is diagnosed.

Humans↗

[Non-traumatic (spontaneous) splenic rupture].

Non-traumatic (spontaneous) rupture of the spleen is a rare condition. Predisposing factors such as haematological disease, malignant tumour, inflammatory disease, infection, connective tissue disease and miscellaneous disorders have been reported. This report describes two patients with ruptured spleens, one of whom used warfarin, the other had a ruptured haemangioma.

Aged↗

[Computed tomography diagnosis of extranodal manifestations in malignant non-Hodgkin's lymphoma].

The data of computed tomography (CT) were used to study the semiotics of extranodal manifestations in 78 patients with varying malignancy non-Hodgkin's lymphomas. The most common lesions were found in the viscera: liver, spleen, peritoneum, omentum, pancreas, adrenals, mesentery. The CT pattern of these lesions is diverse, each site has its own specific features. Combining the clinical manifestations and CT signs of lesions to individual organs, recording the extent of lymphadenopathy will aid in establishing the diagnosis of non-Hodgkin's lymphoma. A lesion detected in some organs located both above and below the diaphragm is a typical feature of high-grade malignancy.

Adrenal Gland Neoplasms↗

Pattern of organ involvement in Burkitt's lymphoma in Ibadan: a review.

A retrospective study was conducted on 127 patients with Burkitt's lymphoma who had partial or complete records of both clinical and pathologic features of their disease. An analysis and description of the anatomical tumor distribution based on post-mortem examinations was made, highlighting lack of correlation between clinical staging and pathologic findings. A consistent observation was the high incidence of involvement of the kidney, liver, and heart in each of the stages (I-III).The data to be presented will clarify at least in part, the unpredictability of response of Burkitt's lymphoma patients to chemotherapeutic agents, because total cell-kill, needed for cure and/or prevention of relapse, is made almost impossible due to the widespread tumor volume carried by the patients.Effective supportive treatment might be a life-saving adjuvant regimen in treatment of Burkitt's lymphoma patients, where the organs so commonly involved might fail to function.

Adolescent↗