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PubMed1987

Effects of lead in the laboratory mouse. Development and social behaviour after lifelong exposure to 12 microM lead in drinking fluid.

The effects of chronic exposure to 12 microM lead, from conception onwards, on development and social behaviour were investigated in the laboratory mouse. Lead was administered as 0.25% solution of lead acetate in the drinking fluid. This level of exposure did not affect reproductive success, but caused decreased birthweight and retarded early development in offspring of treated dams. Mortality prior to weaning was significantly greater in pups treated with lead, and animals treated with lead had significantly reduced body weights throughout their lives. Levels of lead in tissues were greatly increased in all treated animals, with females showing significantly higher levels than males. Behaviour was assessed by ethological methods in paired encounters between unfamiliar animals in a novel environment. At age 3-4 weeks Exploratory Behaviour and Social Investigation were significantly increased and Immobility was significantly decreased in animals of both sexes treated with lead. Social Investigation was also increased at age 7-8 weeks but Exploratory Behaviour was decreased. At age 15-16 weeks Non-Social Activity was increased in males and decreased in females, although Social and Sexual Investigation was not affected in these male-female encounters. Lead-treated males, aged 17-18 weeks, showed significantly shorter latencies to aggression towards unfamiliar males than did controls.

Administration, Oral↗
PubMed2005

Early postnatal protein malnutrition changes the development of social play in rats.

Early protein malnutrition produces structural and functional alterations in the brain and changes the organism-environment interactions. Rats from 26 to 76 days of age were used to study the effects of early postnatal protein malnutrition on the development of social play. During lactation phase the litters were fed diet containing 16% protein (well-nourished) or 6% protein (malnourished). From weaning to the end of behavioral tests well-nourished animals were fed a commercial lab chow diet (well-nourished--W) and the malnourished rats were divided into 2 groups: one was maintained on 6% protein diet (malnourished--M) and the other was fed a commercial lab chow diet (previously malnourished--PM). Pairs of male rats of same diet conditions were tested, at different ages, for three consecutive days. During sessions the following behaviors were recorded: pinning, wrestling, walk-over and rear. The frequency of wrestling and walk-over was significantly higher in malnourished as compared to well-nourished animals (p<0.05). Early protein malnutrition also changed the ontogeny of play behaviors (pinning and wrestling) with developmental retards in M and PM as compared with W animals, especially at 46 and 56 days of age. These results suggest that early protein malnutrition can affect the development of neural mechanisms underlying social play in rats.

Age Factors↗
PubMed2000

Onset and early course as determinants of the further course of schizophrenia.

OBJECTIVE: First treatment contact is preceded by a lengthy prodromal and psychotic prephase. We analysed the occurrence of symptoms and disabilities prior to first contact and their consequences for medium-term illness course. METHOD: A population-based sample of 232 first episodes of schizophrenia was studied retrospectively using the IRAOS and compared with matched peers from the population of origin. Further illness course was studied prospectively at six cross-sections over 5 years from first admission onwards. RESULTS: Three quarters showed a prodromal phase of 5 years (mean) and a 1-year accumulation of psychotic symptoms. First to appear were depressive and negative symptoms and early signs of cognitive and social impairment. Social disability emerged 4 to 2 years before first contact. Further illness course was determined by stage of social development at psychosis onset with the consequence of a significantly poorer course for men than women because of men's earlier illness onset. Symptomatology, type of onset, age and gender influenced social course via stage of social development and, additionally, via young men's socially adverse illness behaviour. CONCLUSION: Social course is determined by individual stage of social development at illness onset and by early illness course. Therefore, early detection and intervention are needed.

Adult↗
PubMed1980

A development in social psychiatry. The systematic study of social bonds.

Psychiatric epidemiology has not until now reached the stage at which the individual's immediate social environment can be examined as a principal independent variable. That handicap may now be overcome by a recent development in social psychiatry: the systematic study of social bonds. Work in this area is providing a method for identifying those elements in social relationships which, when deficient, may be causally related to neurosis. There are considerable technical difficulties in teasing apart cause and effect. These can be tackled by designing intervention trials and by fitting structural equation models to longitudinal data. The evidence so far is at least consistent with, but cannot yet prove, the hypothesis that a deficiency in social bonds is a cause of neurosis.

Community Psychiatry↗
PubMed2005

How does information about sleeping arrangements contribute to nurse practitioners' assessment of development?

PURPOSE: To explore how information about children's sleeping arrangements contributes to nurse practitioners' (NPs) assessment of children's developmental progress at toddlerhood. DATA SOURCES: Selected research articles and a survey of NPs' assessments of development for toddlers engaged in solitary and shared sleeping arrangements. CONCLUSIONS: Research does not provide definitive information regarding the connection between children's engagement in different sleeping arrangements and children's development. In this study, information about how sleeping arrangements played a role in NPs' ratings of toddlers' current and predicted social development and autonomy, but not toddlers' language skills, is presented. NPs' ratings of the development of boys who engaged in shared sleeping arrangements suggested that NPs' viewed this sleeping arrangement as a risk factor for both social development and autonomy. Shared sleeping arrangements for girls were not identified as a risk factor, with some analyses suggesting that shared sleep may have a positive impact on girls' social development. IMPLICATIONS FOR PRACTICE: Assessing children's developmental progress is one task completed by Family and Pediatric NPs. NPs gather information across many sources in making these developmental assessments. Type of sleeping arrangement can be one of these sources as it has been connected to children's developmental progress. However, information available in the literature is inconclusive and often contradictory in regard to how sleeping arrangements impact development. To help clarify how NPs currently use information concerning sleeping arrangements to assess developmental progress, this report describes how sleeping arrangements influenced ratings of 18-month-old toddlers' current and later predicted levels of development. This information can help NPs develop strategies for assessing development in light of information regarding sleep arrangements.

Beds↗
PubMed2005

Neurocognitive and electrophysiological evidence of altered face processing in parents of children with autism: implications for a model of abnormal development of social brain circuitry in autism.

Neuroimaging and behavioral studies have shown that children and adults with autism have impaired face recognition. Individuals with autism also exhibit atypical event-related brain potentials to faces, characterized by a failure to show a negative component (N170) latency advantage to face compared to nonface stimuli and a bilateral, rather than right lateralized, pattern of N170 distribution. In this report, performance by 143 parents of children with autism on standardized verbal, visual-spatial, and face recognition tasks was examined. It was found that parents of children with autism exhibited a significant decrement in face recognition ability relative to their verbal and visual spatial abilities. Event-related brain potentials to face and nonface stimuli were examined in 21 parents of children with autism and 21 control adults. Parents of children with autism showed an atypical event-related potential response to faces, which mirrored the pattern shown by children and adults with autism. These results raise the possibility that face processing might be a functional trait marker of genetic susceptibility to autism. Discussion focuses on hypotheses regarding the neurodevelopmental and genetic basis of altered face processing in autism. A general model of the normal emergence of social brain circuitry in the first year of life is proposed, followed by a discussion of how the trajectory of normal development of social brain circuitry, including cortical specialization for face processing, is altered in individuals with autism. The hypothesis that genetic-mediated dysfunction of the dopamine reward system, especially its functioning in social contexts, might account for altered face processing in individuals with autism and their relatives is discussed.

Autistic Disorder↗
PubMed2002

Music as an aid in the development of the social self.

The development of the social self has been a topic of interest to developmental psychologists for some time. With the recent emphasis placed on the effect of the nuclear family and its increasing paucity, researchers have been even more pressed to develop alternate means to aid in the social effects of family and subsequently enhance a child's assertion of independence. In our paper we explore some of the possible ways by which developmental learning occurs, most notably by implicit or unconscious acquisition. We further provide some historical background explaining the emergence of this unconscious learning. Once we understand the process by which this learning occurs and the historical context in which it operates we can put forth our hypothesis. We suggest that an effective way of aiding or supplementing the role of the family is by providing a theoretical family unit. Specifically we propose that participation in musical or band related activities aids in the emergence of adolescence independence and a healthy self concept.

Adolescent↗
PubMed1978

Cognitive development and social policy.

The city of Warsaw was razed at the end of World War II and rebuilt under a socialist government whose policy was to allocate dwellings, schools, and health facilities without regard to social class. Of the 14,238 children born in 1963 and living in Warsaw, 96 percent were given the Raven's Progressive Matrices Test and an arithmetic and a vocabulary test in March to June of 1974. Information was collected on the families of the children, and on characteristics of schools and city districts. Parental occupation and education were used to form a family factor, and the district data were collapsed into two factors, one relating to social marginality, and the other to distance from city center. Analysis showed that the initial assumption of even distribution of family, school, and district attributes was reasonable. Mental performance was unrelated either to school or district factors; it was related to parental occupation and education in a strong and regular gradient. It is concluded that an egalitarian social policy executed over a generation failed to override the association of social and family factors with cognitive development that is characteristic of more traditional industrial societies.

Child↗
PubMed2002

Recovery from psychosis in schizophrenia and schizoaffective disorder: symptoms and neurocognitive rate-limiters for the development of social behavior skills.

Neurocognitive deficits are believed to be important predictors of functional outcome in chronic psychotic disorders, but few supporting studies have utilized prospective designs and adequate control. The aim of this study was to estimate the relative influence of symptoms and neurocognitive deficits on the development of social behavior skills in a cohort of individuals with schizophrenia or schizoaffective disorder recovering from acute symptom exacerbations. Forty-six individuals were recruited upon discharge from an inpatient unit and completed assessments of symptoms, neurocognitive function, and social behavior at 3-month intervals for 1 year. Correlational analyses and random regression models were used to model social behavioral capacities longitudinally. Social behavior improved modestly (10% improvements in ratings) over the follow-up period for the group as a whole. Disorganized and negative symptoms, as well as neurocognitive deficits in short-term and working memory predicted changes in social behavior over time. Individuals with better working memory function showed significantly greater abilities to recover social behavior skills, whereas those with working memory deficits showed no functional improvement over time. Both symptoms and neurocognitive deficits are important determinants of functional outcome in schizophrenia. It is proposed that clinicians should consider neurocognitive thresholds for treatment response when developing rehabilitation plans.

Adolescent↗
PubMed2002

The social-emotional development of "late-talking" toddlers.

OBJECTIVE: To examine the social-emotional problems and competencies of toddlers who evidenced lags in expressive language without concomitant receptive language delays. METHOD: Maternal report and observation of 14 "late-talking" toddlers was compared with that of 14 control toddlers. Participants were selected on the basis of maternal report of vocabulary production with the MacArthur Communicative Development Inventory Short Forms and by direct assessment with the Mullen Scales of Early Learning. Social-emotional functioning was assessed with the Infant-Toddler Social and Emotional Assessment, the Child Behavior Checklist 1.5-5, and the Vineland Adaptive Behavior Scales-Expanded Form. Toddler affect was observed using the Parent-Child Early Relational Assessment. The Parenting Stress Index Short Form was used to assess maternal stress. RESULTS: Late talkers were rated higher in depression/withdrawal and lower in social relatedness, pretend play/imitation, and compliance on the Infant-Toddler Social and Emotional Assessment and more withdrawn on the Child Behavior Checklist than controls. Observation indicated late talkers were more serious, more depressed/withdrawn, and less interested in play. Late talkers were reported to be lower in socialization on the Vineland. Mothers of late talkers endorsed higher parent-child dysfunction on the Parenting Stress Index. No differences were found for externalizing behaviors or peer relationships. CONCLUSIONS: Early lags in expressive language are associated with poor social-emotional adjustment. Intervention may ameliorate difficulty in linguistic and social-emotional functioning.

Affect↗
PubMed2001

Adolescents' perceptions of social status: development and evaluation of a new indicator.

OBJECTIVE: Eliminating health disparities, including those that are a result of socioeconomic status (SES), is one of the overarching goals of Healthy People 2010. This article reports on the development of a new, adolescent-specific measure of subjective social status (SSS) and on initial exploratory analyses of the relationship of SSS to adolescents' physical and psychological health. METHODS: A cross-sectional study of 10 843 adolescents and a subsample of 166 paired adolescent/mother dyads who participated in the Growing Up Today Study was conducted. The newly developed MacArthur Scale of Subjective Social Status (10-point scale) was used to measure SSS. Paternal education was the measure of SES. Indicators of psychological and physical health included depressive symptoms and obesity, respectively. Linear regression analyses determined the association of SSS to depressive symptoms, and logistic regression determined the association of SSS to overweight and obesity, controlling for sociodemographic factors and SES. RESULTS: Mean society ladder ranking, a subjective measure of SES, was 7.2 +/- 1.3. Mean community ladder ranking, a measure of perceived placement in the school community, was 7.6 +/- 1.7. Reliability of the instrument was excellent: the intraclass correlation coefficient was 0.73 for the society ladder and 0.79 for the community ladder. Adolescents had higher society ladder rankings than their mothers (micro(teen) = 7.2 +/- 1.3 vs micro(mom) = 6.8 +/- 1.2; P =.002). Older adolescents' perceptions of familial placement in society were more closely correlated with maternal subjective perceptions of placement than those of younger adolescents (Spearman's rho(teens <15 years) = 0.31 vs Spearman's rho(teens 15 years) = 0.45; P <.001 for both). SSS explained 9.9% of the variance in depressive symptoms and was independently associated with obesity (odds ratio(society) = 0.89, 95% confidence interval = 0.83, 0.95; odds ratio(community) = 0.91, 95% confidence interval = 0.87, 0.97). For both depressive symptoms and obesity, community ladder rankings were more strongly associated with health than were society ladder rankings in models that controlled for both domains of SSS. CONCLUSIONS: This new instrument can reliably measure SSS among adolescents. Social stratification as reflected by SSS is associated with adolescents' health. The findings suggest that as adolescents mature, SSS may undergo a developmental shift. Determining how these changes in SSS relate to health and how SSS functions prospectively with regard to health outcomes requires additional research.

Adolescent↗
PubMedDate not supplied

Developmental and social factors in Nigerian children's accidents.

Accidents to children are discussed in terms of developmental and social factors in Nigeria. The types of accidents involving children and age trends in accident incidence are reported. Physical, perceptual, cognitive and social development are discussed. Social factors identified are family variables, the physical environment, and attitudes and folk beliefs.

Accidents↗
PubMed1991

[Long-term follow-up in patients with Lennox-Gastaut syndrome. Epileptological aspects, psychomotor development and social adaptation].

In 1989/90 a follow-up was made possible on 72 of 78 patients who have been treated for the supposed or confirmed diagnosis of a Lennox-Gastaut-Syndrome at the university children hospital of Berne between 1964 and 1978. Nine patients were excluded of this study because the diagnosis was proved wrong retrospectively, leaving 63 cases. Of these, eleven patients (17.5%) have died. The remaining 52 (82.5%) were evaluated regarding their epilepsy, psychomotor development and social adaptation. The follow-up was good for 14.3%, intermediate for 23.8% and poor for 44.4%. Bad prognostic factors were found to be: first manifestation of epilepsy during the first year of life, occurrence of infantile spasms or hypsarrhythmia in the EEG and pathological neurological signs at the beginning of the disease. In the course of illness a change of seizure phenomenology was observed. The infantile spasms were seen only during the first three years of epilepsy. After the second year of disease psychomotor seizures became more and more frequent. Atypical absences, already seen at the beginning, were the most frequent form of seizure from the third year of epilepsy until the end of our observations. During the course of disease the frequency of generalized tonic and tonic-clonic seizures decreased little.

Adolescent↗
PubMed2004

The effect of organizational conditions (role conflict, role ambiguity, opportunities for professional development, and social support) on job satisfaction and intention to leave among social workers in mental health care.

This study examined the relationships between the organizational conditions of social workers practicing in mental health agencies and their job satisfaction and intention to leave. A sample of 259 social workers, practicing in sixteen mental health agencies in New York State completed a questionnaire that included several measures: role conflict, role ambiguity, social support, extent of opportunities for professional development, type of work activities, job satisfaction and intention to leave. Results showed that the organizational conditions are strong predictors for job satisfaction and intention to leave. The author suggests that it is possible to find an appropriate balance between the professional expectations of social workers and the business-driven aspect of the mental health care environment.

Community Mental Health Centers↗
PubMed1985

[The function of the universities in strategies of health for all. Contribution to human development and social justice].

This was the working document of the Technical Discussions held in the Thirty-seventh World Health Assembly (1984). It represents a new dimension of activity in the World Health Organization and is one of a series of actions being taken to focus attention on the enormous influence that universities can exert on the effectiveness of health care in the different situations and settings found in the world. The document takes cognizance of the diversity of form, nature, purposes and functions among institutions of higher learning in different societies and no attempt is made to see similarities where none exist. It examines the functional relations between these institutions and their governments and communities in the health for all context in light of the basic imperatives of human development and social justice. The document was produced by a special group formed to consider the subject and made up of more than a dozen health and academic authorities from different universities in all parts of the world. WHO is indebted to them for their contribution to placing these issues in truly worldwide perspective.

Developing Countries↗