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Development of new concepts in vaccines and their effects on the control of infectious diseases (classical swine fever in particular).

Molecular biology and technological advances in DNA recombination have ushered in a new era in vaccinology. In particular, "deleted" vaccines have emerged over the past 10 years. The first such vaccines were used to protect pigs against Aujeszky's disease. The same principles were subsequently applied to the development of vaccines against classical swine fever (CSF), relaunching the debate on whether to use sanitary or medical measures. The decision about the measures to be applied depends on several criteria and factors such as the capabilities of the vaccines to be used in an emergency situation and the local epidemiological situation. Under the light of the last CSF serious epizootic which appeared in Europe in 1997, the effects of the different types of measures are discussed.

Animals↗

Lelystad virus and the porcine epidemic abortion and respiratory syndrome.

Lelystad virus is the causal agent of a relatively new pig disease, variously known as mystery swine disease, porcine epidemic abortion and respiratory syndrome and porcine reproductive and respiratory syndrome. The virus is a small, enveloped RNA virus, that tentatively can be included in a new virus family, the Arteriviridae. The virus has infected pigs throughout the world and seems to persist in many pig populations and in individual pigs. Clinical signs of an infection with Lelystad virus are characterized by late term abortions and still birth in sows, and respiratory disease in piglets.

Abortion, Veterinary↗

[Disease prevention in swine production].

First, it is mentioned that the health status of the population of Swiss swines is very good in comparison to other nations due to the activity of the pig health service (PHS) and that in many places the conditions for a reduction of the use of antimicrobials are already there. Then, the activity of the PHS is described. Its success is base on the obstinate implementation of the eradication programs which are already widely used at the present time in several regions of Switzerland and which have attracted interested specialized practitioners. How the renouncement of the use of antimicrobial growth promoters will affect PHS and non PHS herds remains to be determined. A special paragraph lists the reasons why practitioners often have only little access to swine herds. One reason is the lack of competence. This problem should be solved by an intensification of the graduate and postgraduate education. Finally, the argument for a valorization of an applied and problem-oriented research at the faculties should be put forward.

Animals↗