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The scintigraphy of sacroiliac joints. A comparison of 99mTc-DPD and 99mTc-MDP.

The accumulation of 99mTc-methylene diphosphonate (99mTc-MDP) and 99mTc-dicarboxypropane diphosphonate (99mTc-DPD) in sacroiliac (si) joints was evaluated as a function of imaging time in 22 control patients and 5 patients with sacroiliitis. The controls were injected with either 99mTc-DPD or 99mTc-MDP (12 and 10 patients, respectively) and the patients with sacroiliitis with both agents within 5 days. Both the anterior and posterior views of the si joints were taken. The sacroiliac joint-to-sacrum (SI/S) ratio was calculated with the region of interest method. No statistically significant differences between these bone-seeking agents were found in the SI/S ratios of the control or the diseased patients. A clear overlap of indices (mean +/- SD) was found between the control patients and the patients with sacroiliitis. When the inflamed si joint was divided into three small adjacent areas and the SI/S ratios calculated for these areas, a statistically significant (P less than 0.001) increase in the SI/S ratio was noticed when compared with the SI/S ratio of the whole joint. Comparison of control patients and patients with sacroiliitis showed the most significant differences in the anterior views as well as in the P value: P less than 0.001 in all patients injected with 99mTc-DPD and in most patients injected with 99mTc-MDP. In the posterior views, the significance was less marked. In every case, the inflamed part of the si joint was visible in the anterior views. The background subtraction had the greatest effect on the SI/S ratio of anterior images, but in the posterior views no significance was found.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Evaluation of the involvement of axial entheses and sacroiliac joints in relation to diagnosis: comparison among diffuse idiopathic skeletal hyperostostis (DISH), osteoarthrosis and ankylosing spondylitis.

Since diffuse idiopathic skeletal hyperostosis (DISH) is frequently difficult to differentiate radiologically from the axial involvement of ankylosing spondylitis and osteoarthrosis, some features of these 3 different diseases were compared. The predominantly horizontal nature of the enthesiophyte in DISH and its right preponderance in the thoracic region were demonstrated. This right preponderance was due to the presence of the thoracic aorta located in the left thoracic side. A midthoracic notch was described in DISH which seemed to be confined to noninflammatory conditions, but was not found in ankylosing spondylitis. The importance of sacroiliac computerized tomography to differentiate sacroiliac joint abnormalities associated with DISH from the sacroiliitis of spondylarthropathies was stressed.

Adult↗

Scintigraphy of sacroiliac joints in acute anterior uveitis. A study of thirty patients.

HLA-B27 is a transplantation antigen found in a high proportion of patients with ankylosing spondylitis. Recently, an association has been shown to exist between HLA-B27 and acute uveitis, even in the absence of ankylosing spondylitis. We have examined the HLA antigen profile of 45 patients with acute nongranulomatous anterior uveitis and have confirmed this relation. In addition, using 90mtechnetium stannous pyrophosphate we have been able to demonstrate abnormal bone scan in 19 of 30 patients studied. Such abnormalities are limited to the sacroiliac joints but are otherwise the same as those seen in overt ankylosing spondylitis. Seven of the 19 patients did not have HLA-B27. These factors suggest that acute anterior uveitis may often represent a manifestation of a spondylitic diathesis even in the complete absence of any suggestive symptomatic or radiologic change and, in some cases, even though the antigenic marker HLA-B27 may be absent.

Adolescent↗

Concomitant sacroiliac joint pain in patients with lumbar disc herniation: case series.

Recent studies have shown that not all lumbar disc herniations are symptomatic and that when followed longitudinally, these patients develop back pain independent of the previous imaging study. This is a case report of two patients with radicular symptoms and lumbar disc herniations that underwent diagnostic injections to locate their pain generator. Both patients failed to respond to transforaminal epidural steroid injections. Transforaminal injections can be diagnostically sensitive for radicular pain but not specific. This is a direct result of the spread of medication to other levels in the epidural space, thus affecting multiple levels of innervation. Follow-up with two sacroiliac injections gave significant relief of their pain. They were both treated conservatively for sacroiliac joint pain and did well. One remained pain free after several months and the second remained with minimal pain until she presented again in her 3rd month of pregnancy with return of her pain. The differential diagnosis of lumbar radicular pain is discussed as well as the authors' experience in using diagnostic injections.

Adult↗

Appearance and incidence of sacroiliac joint disease in ventrodorsal radiographs of the canine pelvis.

Ventrodorsal (VD) radiographs of cadaveric pelves of large and giant breeds (n = 40) and of the corresponding bone specimens were made. Gross changes seen in the specimens were marked with metal wire or radiopaque paint to relate radiographic changes to the postmortem appearance of degenerative sacroiliac (SI) joint lesions. Two positioning techniques were used, resulting in two radiographs for each specimen. The techniques used were: (1) pulling the pelvic limbs caudally, with gentle traction producing a view of the sacrum in almost parallel alignment between the sacrum and the X-ray film (we have termed this a "central SI view") and (2) pulling the pelvic limbs caudally with greater traction than above, resulting in maximal inclination of the sacrum with respect to the X-ray film (we have termed this an "angled SI view"). Lesions of the supportive soft connective tissue could be imaged on the central and angled SI views, whereas angled SI views allowed better identification of lesions of the synovial SI joint. The insights gained in the above study were then used in a retrospective examination of 145 routine ventrodorsal radiographs of the pelvis (i.e., 290 sacroiliac joints) to determine the incidence of degenerative changes of the SI joint in large dogs. The lesions most commonly observed were calcification of the supportive soft connective tissue (n = 184/290), whereas lesions of the synovial SI joint were less frequent (n = 86/290). The degree of central or angled projection obtained in standard ventrodorsal radiographs was noted to be significantly (P < 0.05) associated with age, body conformation, anesthetic status, and the presence of spondylosis deformans at the lumbosacral junction. In contrast, SI joint disease and the gender of the animal did not affect the SI view achieved in VD radiographs.

Animals↗

Relation between form and function in the sacroiliac joint. Part II: Biomechanical aspects.

The amount of friction between the articular surfaces of sacroiliac (SI) joints was determined and related to the degree of macroscopic roughening. Results show that articular surfaces with both coarse texture and ridges and depressions have high friction coefficients. The influence of ridges and depressions appears to be greater than that of coarse texture. The data are compatible with the view that roughening of the SI joint concerns a physiologic process.

Adult↗

Can the sacroiliac joint cause sciatica?

In this brief study we provide evidence that earlier and more recent findings pertaining to the anatomy and physiology of the sacroiliac joint suggest that dysfunction in this joint could, similar to a herniated lumbar disc, produce pain along the sciatic nerve. These observations might explain some of the cases of sciatica in which no disc pathology can be found.

Journal Article↗

Quantitative scintigraphy of the sacroiliac joints.

The effects of age and laterality on sacroiliac (SI) to sacral indices and ratios were assessed in 62 patients. For the 14 controls, the left mean SI to sacral index was significantly higher than the right one. There was no correlation between age and SI to sacral ratio (= average of right and left index). The mean ratio in 36 patients with sacroiliitis and 12 patients with low back pain was not significantly different from that of the controls, with a clear overlap of indices between controls and sacroiliitis patients.

Adult↗

CT of sacroiliac joints in secondary hyperparathyroidism.

Computed tomography (CT) was used to evaluate the sacroiliac (SI) joints in 12 patients with secondary hyperparathyroidism. The CT scan was superior to conventional radiography in all patients, and correlated well with previous reports of SI abnormalities in chronic renal failure.

Adult↗

Lateral branch blocks as a treatment for sacroiliac joint pain: A pilot study.

BACKGROUND AND OBJECTIVES: Pain arising from the sacroiliac (SI) joint is a common cause of low back pain for which there is no universally accepted, long-term treatment. Previous studies have shown radiofrequency (RF) procedures to be an effective treatment for other types of spinal pain. The purpose of this study was to determine the efficacy of reducing SI joint pain by percutaneous RF lesioning of the nerves innervating the SI joint. METHODS: Eighteen patients with confirmed SI joint pain underwent nerve blocks of the L4-5 primary dorsal rami and S1-3 lateral branches innervating the affected joint. Those who obtained 50% or greater pain relief from these blocks proceeded to undergo RF denervation of the nerves. RESULTS: Thirteen of 18 patients who underwent L4-5 dorsal rami and S1-3 lateral branch blocks (LBB) obtained significant pain relief, with 2 patients reporting prolonged benefit. At their next visit, 9 patients who experienced >50% pain relief underwent RF lesioning of the nerves. Eight of 9 patients (89%) obtained >/=50% pain relief from this procedure that persisted at their 9-month follow-up. CONCLUSIONS: In patients with SI joint pain who respond to L4-5 dorsal rami and S1-3 LBB, RF denervation of these nerves appears to be an effective treatment. Randomized, controlled trials are needed to further evaluate this procedure.

Adult↗

Complex motion tomography of the sacroiliac joint. An anatomical and roentgenological study.

To find a better method for diagnosing sacroiliac (SI) joint disease, an anatomical approach was combined with conventional roentgenology, complex motion tomography and computed tomography. Complex motion tomography is suggested as the method of choice in the investigation of the SI-joint. Because of its complex (sinusoidal) form, the dorsal portion of the joint has to be tomographed in frontal projection and the middle and ventral portions in oblique projection. In 56 patients, referred for probable ankylosing spondylitis, 72 SI joints were investigated. Based on plain radiography six and on frontal tomography five SI joints were diagnosed as normal. However, based on oblique tomography 31 joints were diagnosed as normal.

Female↗

Sacroiliac joint abnormalities in paraplegics.

We studied 186 paraplegic patients to clarify the pathogenesis of the sacroiliac (SI) joint abnormalities reported in these patients. Partial or complete fusion of SI joints was noted in 47 patients (25%), and milder degrees of abnormalities of these joints were present in 27 patients (15%). The abnormalities differed from those seen in ankylosing spondylitis and were found more commonly in patients with high levels of cord injury. It is likely that trunk mobility is necessary to maintain integrity of SI joint and that absence of such mobility compromises SI joint structure in many paraplegics.

Adolescent↗