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Clinical comparison of small-and large-caliber cutting needles for biopsy.

A 22 gauge "skinny core" (Madayag) biopsy needle, an 18 gauge Menghini needle, and a 14 gauge Tru-cut needle were compared in 51 patients. The Madayag needle was found to have a high recovery rate and provided adequate histological information in a large percentage of cases. However, the larger needles more consistently demonstrated a higher recovery rate and diagnostic specimen than the Madayag needle. The authors recommend that the radiologist become familiar with all three types of needles to facilitate selection of the proper instrument in each case.

Biopsy, Needle↗

Impassable ureteral strictures: management with percutaneous ureteroneocystostomy.

Sixteen of 227 patients referred for percutaneous placement of a ureteral stent had impassable stenoses. Stenoses were benign (n = 8) or attributed to malignant retroperitoneal neoplasm (n = 8). Electrocautery was used to create a neotract between the stenosed ureter and the bladder or ileal loop. A double-J stent was placed after dilation of the tract by use of angioplasty. Neotracts were established and stents were placed in all patients. Complications (digestive tract fistulas) developed in two patients. This technique is safe if the electrode is placed close to the bladder or ileal loop. The procedure can be used as an alternative to surgery or permanent nephrostomy or in initial treatment of benign anastomotic stenosis.

Aged↗

Medial border of the perirenal space: CT and anatomic correlation.

PURPOSE: To explore the mode of spread of disease between the perirenal space and the perivascular central retroperitoneum and to determine the anatomy along the medial border of the perirenal space. MATERIALS AND METHODS: Anatomic dissection, injection of latex, and observation of cross sections of the abdomen were performed in nine cadavers. Attention was paid to the juncture of the central prevertebral, perivascular, and extraperitoneal regions, and the perirenal space. Anatomic findings were correlated with observations made at computed tomography (CT) in 82 patients with retroperitoneal hemorrhage (n = 24), inflammation (n = 37), and neoplasia (n = 21) involving the perirenal spaces or the central retroperitoneum. RESULTS: Along most of the length of each kidney, no apparent fascia separates the perirenal space from the central retroperitoneum. At this location, septa between fat lobules form a fenestrated multitier barrier. These septa were imperceptible on CT scans obtained in healthy individuals. After injection of latex in cadavers, this potential barrier was seen. In the clinical study, spread of disease was allowed in only 38 (30%) of 128 instances of potential spread. Spread was facilitated along the renal vessels and the interlobular septa. CONCLUSION: Beyond the kidneys, the renal fascia is closed, forming a cone superiorly and an inverted cone inferiorly. A network of interlobular septa acted as a barrier or pathway to the free spread of disease from the perirenal space to the central retroperitoneum or from the central retroperitoneum to the perirenal space.

Adult↗

Bronchogenic cyst. A rare differential diagnosis of retroperitoneal tumors.

Subdiaphragmatic bronchogenic cysts are rare, and those located retroperitoneally are exceptional. A review of the English-language literature revealed only 16 reported cases. We describe an additional case of a retroperitoneal cyst presenting as an asymptomatic adrenal mass and discuss clinical, radiographic, surgical and pathological findings as well as its embryological background.

Bronchogenic Cyst↗

[HLA-antigens in germ cell tumors of various sites].

In 41 children with germ-cell tumors differently localised and 301 healthy unrelated subjects, 22 HLA antigens of A and B loci were tested. No statistically significant difference in the frequency of HLA antigens--with exception of a higher frequency of HLA-A28 (14,63% versus 4,32% in the controls, chi 2 = 5,69) before the correction of p value--was found. The cause of the rare associations between the tumors and HLA was discussed.

Child↗

Retroperitoneal varicose veins simulating lymph nodes.

A case of retroperitoneal varicose veins simulating neoplastic masses in a patient with unknown portal hypertension is presented. The radiological modalities of choice in differential diagnosis are briefly discussed. The use of contrast-enhanced computed tomography is recommended.

Diagnosis, Differential↗

Extrarenal retroperitoneal angiomyolipoma.

The clinical and pathological findings in a patient with extrarenal angiomyolipoma arising in the perinephric space are presented. This location has been reported only rarely and sets forth some diagnostic and therapeutic difficulties that are also discussed.

Angiomyolipoma↗

Cryptorchidism and extragonadal germ cell tumor.

A patient with an extragonadal germ cell tumor and a history of bilateral cryptorchidism is reported. The rarity of this concurrence in a single patient is discussed. The necessity for thorough investigation of the cryptorchid testes in patients with metastatic germ cell cancer remains essential.

Adult↗

Cytology of fine needle aspirates of primary extragonadal germ cell tumors.

OBJECTIVE: To describe the characteristic cytologic features of fine needle aspirates (FNAs) of primary extragonadal germ cell tumors (PEGCTs). STUDY DESIGN: Thirteen patients with PEGCTs, including 2 seminomas, 2 mixed germ cell tumors, 3 immature teratomas, 1 choriocarcinoma and 5 yolk sac tumors (YSTs) were studied. The final diagnosis of PEGCT in all cases was established by histologic examination of the tumor tissues. Fine needle aspiration was done on either the primary tumor or metastatic foci. The aspirates were stained with one of the Romanovsky stains and Papanicolaou stain. RESULTS: Each type of PEGCT has its own morphologic characteristics. In seminoma, the tumor cells are large and noncohesive, with one to several distinct nucleoli; some lymphocytes are also present. YSTs show many pleomorphic cells with vacuoles in the cytoplasm and nuclei; tumor cells frequently aggregate in a microglandular or papillary pattern. Choriocarcinoma consists of syncytiotrophoblasts and cytotrophoblasts. The former are very large cells with eosinophilic cytoplasm, one to several nuclei and distinct nucleoli; the latter are medium-sized cells with vacuolated, basophilic cytoplasm and eccentric nuclei. Immature teratomas are composed of a mixture of cell types, including elongated epithelioid cells, mesenchymal cells and many large, naked, amorphous nuclei with a homogeneous chromatin pattern. Diagnosis of mixed germ cell tumor is difficult but can be made if two or more subtypes of tumor cells are observed in the FNA. CONCLUSION: Cytologic examination of FNAs of primary or metastatic lesions of PEGCTs, stained either with Romanovsky or Papanicolaou stain, is of diagnostic value for such diseases. The use of immunochemistry can help to confirm the cytologic impression.

Adolescent↗

Extragonadal germ cell tumor invading the prostate.

To our knowledge, only 3 patients with an extragonadal germ cell tumor of the prostate have been described in the literature until now. We here present a patient with a germ cell tumor arising in the retroperitoneum, invading the prostate, which was successfully treated by a combination of chemotherapy and nonmutilating surgery.

Adult↗

Percutaneous cytodiagnosis of abdominal masses by ultrasound guided fine needle aspiration biopsy.

A review was made of 168 ultrasound guided fine needle biopsies on 145 patients. Fifty-seven biopsies were from the pancreas, 40 biopsies from the liver, 28 from the kidney, 26 from the abdomen and 17 from the retroperitoneum. The total accuracy rate was 66 per cent varying from 50 per cent in abdominal lesions to 83 per cent in hepatic lesions. The differences of the results are discussed as are the indications and the role of ultrasound guided fine needle puncture compared with other modalities.

Abdominal Neoplasms↗

Hepatic arterial infusion chemotherapy in sarcoma liver metastases: a report of 6 cases.

AIMS AND BACKGROUND: Liver metastases in patients with sarcoma are rare and associated with a poor prognosis. The experience with liver-directed therapies, eg hepatic arterial infusion, in these patients is limited. METHODS: Six patients with sarcoma metastatic to the liver (4 patients with gastrointestinal stromal tumors and 2 patients with leiomyosarcoma) were treated by hepatic arterial infusion in our center over a 12-year period. Since the experience was limited, a pooled analysis of reports with data on survival of 22 individual patients was performed. RESULTS: None of the 5 assessable patients responded to the therapy, and liver metastases progressed in all patients. The median survival was 20 months. In the pooled analysis, partial response was observed in 10 of 21 assessable patients (48%) and median survival was 20 months. The survival was significantly longer in responding patients compared to nonresponders (35 vs 14 months; logrank test, P = 0.009). CONCLUSIONS: Hepatic arterial infusion has little efficacy in the treatment of sarcoma metastatic to the liver. More promising results have been reported for chemoembolization. The survival of responding patients seems to be better compared to non-responders.

Adult↗

The role of surgery in non-localized neuroblastoma. Analysis of 59 cases.

The authors considered 59 stage III and IV neuroblastoma cases, which were observed from January 1967 to June 1979. 13 patients (13/59 = 22%) are surviving in complete remission 3 years after surgery: 9/20 (45%) with stage III and 4/39 (10%) with stage IV disease. The children subjected to complete surgical excision are all alive irregardless of age; the children who were not operated on or subjected to a biopsy, have all died. Of the 33 patients who underwent a reductive excision, 6 (all under 2 years of age) are in complete remission (18%). A better prognosis was found in those patients in whom the site of the primary tumor was at the mediastinal level. These data show the importance of the role of the surgeon in the multidisciplinary treatment of stage III and IV neuroblastomas; our experience is also favorable to the practice of second-look surgery.

Adrenal Gland Neoplasms↗