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At least 397 records · Page 22Linked to original sources
PubMed1991

Triphalangism in thumb polydactyly: an anatomic study on surgically resected thumbs.

Surgically resected thumbs in preaxial polydactyly were submitted to anatomic dissection to detect a triphalangeal thumb. Radiologically, two particular categories of thumbs with duplication at the metacarpophalangeal joint were seen. The surgically excised thumbs of either the radial or the ulnar member were preserved for dissection. Depending on the number of phalanges as well as on osteocartilaginous structures, the thumbs were classified into three groups. In the first group, the thumbs consisted of three phalanges but had absent joint formation between the phalanges and metacarpal. The second group consisted of three phalanges with two well-formed joints between them. The third group of thumbs also had three phalanges but had only one interphalangeal joint between them. In all three groups, morphologic features and clinical criteria are discussed.

Humans↗
PubMedDate not supplied

An X-linked recessive mutation producing cleft palate, crooked tail, and polydactyly in mice.

Palate-tail-digits abnormality (ptd) is a new X-linked recessive mutation affecting the morphogenesis of the mouse. It maps proximal to Tabby. Hemizygous males and homozygous females exhibit skeletal malformations of the tail, polydactyly of the hind feet, and in about 60% of the cases a cleft palate. A very high level of postnatal mortality is observed even among the mutants without a cleft palate.

Abnormalities, Multiple↗
PubMed1990

Fibula dimelia in association with ipsilateral proximal focal femoral deficiency, tibial deficiency, and polydactyly. A case report.

A 16-year-old girl with bilateral tibial deficiency, left fibula dimelia, left proximal focal femoral deficiency, polydactyly, and congenital heart disease is now ambulatory and able to attend public school. This combination of anomalies has been overcome by cardiac surgery followed by Boyd-type amputation, prosthetic restoration, and therapy. The shortened left distal femur was lengthened by implanting both amputation fibulae proximally. In the same surgery, the amputation os calcis was fused distally to these fibulae. The right fibula was disarticulated at the knee. The female patient was fitted with bilateral knee disarticulation prostheses. She became fully ambulatory with a walker, progressing to bilateral forearm crutches. Recurrent deformity at the fusion site of the left femoral segment to the fibulae required a subsequent wedge osteotomy and multiple surgeries during the years following. Today she remains ambulatory with the use of nonaxillary crutches, attends public school, and is without pain. She takes part in athletics within the range of her abilities and hopes to obtain a driver's license and use a modified car. She is independent and well adjusted. Her progress has been followed from the age of 11-and-one-half months to present.

Abnormalities, Multiple↗
PubMed1987

Polydactyly.

Polydactyly is a fairly common, genetically induced deformity of the hands and feet found more often in blacks than in whites. Careful clinical and radiographic evaluation should be made prior to treatment because the complexity of the deformity ranges from a simple soft tissue appendage to a completely developed accessory ray. Treatment usually consists of surgical excision of the least functional, least developed digit. Hallux varus, angular deformities, and a splayed forefoot are common postoperative complications.

Black People↗
PubMed1985

Polydactyly.

The different etiologies and treatments of preaxial, postaxial, and central polydactyly are reviewed.

Congenital Abnormalities↗
PubMed1979

Postaxial polydactyly, hallux duplication, absence of the corpus callosum, macrencephaly and severe mental retardation: a new syndrome?

A male patient presented with a pattern of congenital malformations including macrocephaly, absence of the corpus callosum, hypertelorism, small nose, bilateral inguinal hernias, postaxial polydactyly of all limbs and duplication with syndactyly of the big toes. His development was marked by growth retardation, repeated infections, cyanotic spells, seizures, and gross motor and mental retardation. This case probably represents a newly recognized malformation syndrome of hitherto unknown etiology.

Abnormalities, Multiple↗
PubMed1970

Polydactyly and other minor stigmata associated with 46,XX-47,XX,D+ mosaicism.

Mosaicism for normal and D-trisomic cells was found in a female child whose presenting abnormalities at birth were polydactyly of the left hand and foot, hemangiomata on the forehead and lumbosacral region, slightly peculiar facies and unusual dermal patterns. Her course during the first 27 months of life was characterized by normal growth, absence of clinical evidence of congenital heart disease, moderate developmental retardation, tonguetie and toe-walking. Trisomic cells were more numerous than normal cells in skin cultures, whereas the reverse was true for peripheral leukocytes.

Abnormalities, Multiple↗
PubMedDate not supplied

Surgical approach to polydactyly.

Polydactyly of the foot most often affects the first or fifth rays although any digit may be involved. In order to make possible the restoration of normal foot structure and function, it is essential to make a thorough clinical and radiographic examination.

Adult↗
PubMed1982

[Short rib-polydactyly syndrome of the Saldino-Noonan type in 2 siblings].

Two stillborn female siblings with short rib-polydactyly syndrome type I (Saldino-Noonan) are described. Besides the characteristic narrow thorax, the pronounced micromelia and a severe dysplasia of the skeleton, a series of organic malformations have been found, in particular in the gastro-intestinal tract and in the urogenital system. The clinical, radiological and anatomo-pathological differences between the four presently known types of the SRP syndrome are described. The importance of postmortem X-ray diagnosis and of genetic counseling (autosomal recessive transmission) is emphasized.

Abnormalities, Multiple↗
PubMed1981

[Ehler-Danlos syndrome (type V) with urethra bifida and polydactyly: an unusual combination].

Ehlers-Danlos syndrome is currently regarded as a connective tissue dysplasia. Its genetic, biochemical, histological and clinical features are described, together with a personal case in a patient who presented the fundamental symptoms, plus polydactyly and bifid urethra. This association had not been hitherto reported in the literature. The case itself is classed as Ehlers-Danlos syndrome type V.

Abnormalities, Multiple↗
PubMed1981

Congenital polydactyly and polymetatarsalia: classification, genetics, and surgical correction.

Polydactyly, one of the most common congenital deformities, is inherited and often several members of a family are affected. The condition may range from a small amount of additional soft tissue without osseous structure to a complete, fully developed extra digit or digits. The primary treatment is surgical removal. In this paper, the authors review and discuss the genetic basis, classification, and surgical correction of the conditions.

Adult↗
PubMed1976

Rudimentary polydactyly presenting as a claw.

A patient with a congenital claw-like lesion of the finger was studied to determine the nature of the tissue. A variety of biochemical techniques and histological examinations indicated that the lesion was an example of rudimentary polydactyly covered with stratum corneum rather than an accessory nail.

Adult↗