Use of 3-azabicyclo [3.2.1] octane in the Mannich reaction.
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Amino Alcohols↗
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Improved method for preparing 3-azabicyclo(3.2.1)octane hydrochloride and the synthesis of its phenothiazine derivatives.
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Aluminum↗
Bis-quaternary ammonium compounds: derivatives and congeners of bicyclo(2.2.2)octane.
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Animals↗
Cholinergic activity of 2-azabicyclo(2.2.2)octane analogs of acetylcholine.
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Acetylcholine↗
Evaluation of 2-azabicyclo[2.2..2]octane analogs of 4-anilidopiperidine analgesics.
Eight analogs of the fentanyl-type analgesics, in which the piperidine ring is restricted into a boat conformation, were evaluated for analgesic activity. All analogs were less active than fentanyl, but interesting conformational and structural relationships were observed. Results of the study are discussed.
Analgesics↗
Free radicals and singlet oxygen scavengers: reaction of a peroxy-radical with beta-carotene, diphenyl furan and 1,4-diazobicyclo (2,2,2)-octane.
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Bridged Bicyclo Compounds↗
Effects of SC-26096(2-methyl-3-oxo-2azabicyclo(2.2.2.)octan-6-exo-yl 5-(4-biphenylyl)-3-methyl valerate), a new hypolipidemic agent, on mitochondrial respiration and oxidative phosphorylation.
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Adenosine Triphosphatases↗
Inhibition of amine uptake by 4-phenyl-bicyclo(2,2,2)octan-1-amine hydrochloride monohydrate (EXP 561) in rats.
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Amines↗
The interaction of 4-alkyl derivatives of 2,6,7-trioxa-1-phosphabicyclo [2,2,2] octanes with cyclic adenosine 3',5'-monophosphate phosphodiesterase, and with cyclic adenosine 3',5'-monophosphate binding proteins.
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3',5'-Cyclic-AMP Phosphodiesterases↗
Cyclic nucleotide concentrations in the brains of mice treated with the convulsant bicyclic organophosphate, 4-isopropyl-2,6,7-trioxa-1-phosphabicyclo[2,2,2] octane.
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Animals↗
5-Methyl-4-oxo-octane-i,8-dioic acid as a microbiological degradation product of cholic acid.
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Journal Article↗
Charge transfer between water and octane phases by soluble mitochondrial ATPase (F1), bacteriorhodopsin and respiratory chain enzymes.
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Adenosine Triphosphatases↗
An inhibitor of dopamine uptake, LR5182, cis-3-(3,4-dichlorophenyl)-2-n,n-dimethylaminomethyl-bicyclo-[2,2,2]-octane, hydrochloride.
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Animals↗
Blockade of monoamine uptake by 1-amino-4-phenylbicyclo(2,2,2)octane (EXP 561) in rat brain and heart.
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Animals↗
Studies on 4-(p-bromophenyl)-bicyclo (2,2,2) octan-1-amine as an inhibitor of uptake into serotonin neurones.
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Animals↗
In vivo effects of LR5182, cis-3-(3,4-dichlorophenyl)-2-n,n-dimethylaminomethyl- bicyclo-[2,2,2]-octane hydrochloride, an inhibitor of uptake into dopamine and norepinephrine neurons.
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Animals↗
Structure-toxicity relationships of 2,6,7-trioxabicyclo(2.2.2)octanes and related compounds.
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Animals↗
Structure--toxicity relationships of 1-substituted-4-alkyl-2,6,7-trioxabicyclo[2.2.2.]octanes.
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Animals↗