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PubMed2001

[Trueness of modern natural science (1): the scientific revolution and the problem of philosophy].

How can one characterize modern Europe? This problem is essentially related to the meaning of modern natural science, which was developed during the scientific revolution. Then how did viewpoints change during this revolution? The answer to this question also determined the basic character of modern philosophy. Through the examination of Aristotle's geocentric theory and kinematics, I have come to believe that the defect of Aristotle's was that he concluded that a visible sense image is an actual reflection of the reality as it is. From this point of view, the traditional theory of truth called "correspondence theory" is found to be an insufficient one. Therefore, in this paper I will show that the methodological and philosophical question "How do we see reality among phenomena?" is a very important one. This question is the one Plato struggled with, and also the one which guided Kant. It may be said that this can be seen as a group for a new metaphysics as a basic theory of reality.

History, 16th Century↗
PubMed1999

A reevaluation of the sex prediction accuracy of the minimum supero-inferior femoral neck diameter for modern individuals.

The results of an independent test of the minimum supero-inferior femoral neck diameter as a sex predictor are presented. Seidemann et al. (1) generated discriminant functions for Caucasians, African-Americans, and a combined race sample from the Hamann-Todd skeletal collection. Jackknifed classification matrices and the use of independent, random validation samples indicated a sex prediction accuracy in the 90% range. This, combined with a high rate of preservation, makes the femoral neck a significant measure for forensic applications. However, the method has not been evaluated on a truly modern sample. Data were collected for 94 males and 49 females from the Documented Collection at the University of New Mexico. The sample consists of 94 Caucasians, 33 African Americans, three modern Native Americans, two Hispanics, and 11 individuals of unknown ancestry. All individuals were born after the turn of the century. We evaluate the accuracy of the discriminant functions generated from the Hamann-Todd control sample. For Caucasians, 83% were correctly classified, for African Americans 97% were correctly classified and for the combined race function 85% were correctly classified. This decrease in accuracy is the result of the increase in African American male and all female sample means. This effectively decreases the separation between males and females for the femoral neck diameter. We generate new discriminant functions from the modern data and jackknife the classification matrices. The Caucasian function was 84% accurate, the African-American function was 82% accurate and the combined sample function was 85% accurate. The femoral neck may provide a useful alternative to multivariate techniques for individuals who are poorly preserved.

Adult↗
PubMed2000

Polyomavirus JC genotypes in an urban United States population reflect the history of African origin and genetic admixture in modern African Americans.

The human polyomavirus JC (JC virus), a small, circular, double-stranded DNA virus, has a worldwide distribution and is excreted harmlessly in urine by 20% to 70% of adults. DNA sequence analysis has identified seven distinct genotypes that likely coevolved with modern humans, although the mode of virus transmission is unknown. Type 1 is European in its distribution. Types 2 and 7 are Asian, while Types 3 and 6 are African. Type 4, closely related to Type 1, is of uncertain origin, having been found in population groups in parts of Europe and in the United States, but not in Africa. Here we have studied the JCV partial genomic DNA sequences amplified by polymerase chain reaction techniques from urines of an urban, mainly African American population cohort from Washington, D.C. The predominant genotype identified was Type 4 (32/78 JCV strains, 41%). Type 1 strain was found in 32% of African Americans, while JCV Type 3 strain was found in 18% of African Americans. These African strains have persisted in modern African Americans after 200 to 400 years of minority existence and genetic admixture in the New World. An ancient West African genotype, Type 6, was absent in this African American cohort. However, one Type 6 strain was found in a patient from Sierra Leone (West Africa), domiciled in the United States for 20 years. Type 2A, the most common subtype in Native Americans, was seen in only two African-Americans (3%). A Type 7 strain, previously reported only in Taiwan and South China, was identified in a Vietnamese immigrant. These data support the history of African origin, migration, and genetic admixture of modern African Americans. Analysis of JCV strains in the present American populations provides a novel tool for reconstructing human migrations and genetic admixture in the New World.

Adolescent↗
PubMed2000

[Increased occurrence of allergy--is modern life style the cause?].

BACKGROUND: There is strong evidence that an increase in the occurrence of allergic diseases has taken place in industrialised countries over the last decades. The causes of this increase are unknown, but it seems to be linked to affluence and a modern, "westernized" lifestyle. MATERIAL AND METHODS: Three international research papers are reviewed and discussed in the context of current knowledge of immunoregulatory effects from microbial and allergen exposure. RESULTS: A German report indicates that early attendance (before one year of age) at daycare centres reduced the risk for allergy development in children from small, but not from large families. A Swiss and a Swedish paper report that children of farmers, or students attending anthroposophic Steiner schools had less allergic manifestations than their peers in the same local communities. INTERPRETATION: The findings suggest that groups practising a somewhat simple, "old-fashioned" lifestyle within a modern community have a reduced risk of developing allergic diseases. Proper microbial stimulation of the immune system, possibly via the bacterial flora on the mucosal surfaces of the upper airways and the gut, may act to reduce the risk of becoming allergic. Insufficient microbial stimulation of the immune system may be a "deficiency disease" of modern society, leading to allergy.

Adolescent↗
PubMed2000

[Medico-legal certification of fatal cases after drug: abuse in the light of modern toxicological analysis].

Introduction of modern instrumental methods for toxicological analysis make possible a detection and identification of xenobiotics in different kind of multicomponents biological samples (plant sources of narcotics, body fluids and tissues of abusers) on a low concentration level. In this way a range of possibilities for the interpretation of toxicological results was enlarged. General medicolegal trends are strictly connected with modern analytics and they can be discussed on the basis of drug--users and fatal cases of intoxications with narcotics. Toxicological findings of these cases were worked out by means of modern analytical method--liquid chromatography with mass detection (LC/MS).

Adolescent↗
PubMedDate not supplied

[When was modern science born? Homage to the memory of Professor Arturo Rosenblueth at his birth centennial].

The Renaissance savants essentially repelled the scholastic translations and commentaries of the ancient writings. Nevertheless they did not reach a modern vision of the experimental science. Moreover, the education at the universities was not credited for the science's development. In fact, the academic training of students was rather precarious. The first professional associations, such as the "Royal College of Physicians" of London, were not any better. Regarding hermetic influence on the Renaissance thought, the cultured and philosophical reformed magic (the so called white magic) was the equivalent of science at the time. Once the animistic universe, operated by magic, is transformed into the mathematical universe, operated by mechanics, the era of science came into being. This movement began during the post-Renaissance age and gradually progressed following the physical-mathematical orientation of Galileo and his pupils: Borelli, Fabrizi, Santorio, Harvey, etc. They initiated the physiological studies and introduced the quantitative method into the research field. Harvey's circulatory doctrine was the first adequate explication of an organic phenomenon and a starting point for the way toward experimental physiology. However the English physician did not leave completely the pre-scientific era, as can be inferred from his monography on animals reproduction. In this work, some points suggesting the birth of modern scientific reasoning alternate with confused, vague and capricious assertions. In fact, the modern science did not arise suddenly, but was elaborated and sustained slowly starting from the XVII century: the Galileo's century.

History, 15th Century↗
PubMed2001

[Characteristics of modern means of armament].

The manifestation of unstable modern piece is the constant local armed conflicts. Participation in this conflict requires from physicians the knowledge of modern fighting trauma and fighting pathology. New types of weapons and peculiarities of injuries they cause were the subject discussed in the last International Congresses devoted to the military medicine. Plenty of information concerning the problem of medical support in modern armed conflicts requires purposeful development of creative thought in the future medics, reserve officer, as well as improvement of educative process. Creation of test "block" on different disciplines of military education will contribute to realization of module principle of educative process organization. It will permit to improve the educative process in more short periods.

Blast Injuries↗
PubMedDate not supplied

[Training of the modern clinical physician and public health managers].

Arguments of Russian and foreign specialists that the activities of a modern physician are based on knowledge, habits and skills of a clinician and experience, habits and skills of a manager are discussed. The author proves that managing skills acquired by physician as an element in his/her professional activity through experience should be supplemented by knowledge of modern theory and practice of management. In the twenty-first century modern theory and practice of management should become a universal basis and element of professional cooperation of clinical physicians, physicians working in administration of public health organs and institutions, and public health economists.

Adult↗
PubMed1994

[A comparative analysis of two historical approaches to the formation of the modern clinical medicine].

From the perspective of research methodology, it may be said to exist two kinds of different historical approaches with regards to the formation of modern clinical medicine at the turn of the nineteenth century. One is to explain this in terms of the agency or structure that is associated with research topic. This historical view assumes that the Western scientific rationalism is characterized by the unity of Western tradition and its evolution as continuity. Its main focus is given either on how French revolution and war affected the growth of clinical medicine and the hospital reform movement or on how Paris Clinical School contributed to the birth of modern clinical medicine. The other is, according to Michel Foucault, to analyze how medical discourses are related to social (institutional) practices. Following Canguilhem's history of concepts, Foucault traces the historical development of the concept of disease. Elizabeth A Williams, another proponent of this method, conceptualizes the eighteenth-century medicine as three different medical discourses--anthropology, physiology and philosophical medicine, and analyzes how their structural fragmentation were transformed into the modern establishment of clinical medicine in the nineteenth century. ...

Clinical Medicine↗
PubMed1996

Aristotle's ethical theory & modern health care.

The Greek physician of antiquity - Hippocrates (460-356 B.C.) is called the Father of Modern Medicine and the Hippocratic Oath to which doctors of modern medicine traditionally and formally express their allegiance, forms the basic foundation of medical ethics. The tradition of Western ethical philosophy began with the ancient Greeks. From Socrates (469-399 B.C.) and his immediate successors, Plato (427-347 B.C.) and Aristotle (384-322 B.C.), there is a clear line of continuity, through Hellenistic period (from the death of Alexander the Great (323 B.C.) to the end of Ptolemic dynasty (30 B.C.) and the Roman annexation of Egypt - broadly post-Aristotelian and medieval thought to the present day. But the society has qualitatively and quantitatively changed since the Industrial Revolution in the late 18th and 19th centuries. Society, today, is just a collection of discrete individuals, each with his or her own purposes and interests. Hence it has become almost imperative to apply the principle of autonomy to issues in the ethics of health care. The aim of this short essay is, therefore, an attempt to explore the relevance, if any, of Aristotelian ethical theory to the modern health care.

Comprehensive Health Care↗
PubMed1994

[The authentication of modern Japanese acupuncture].

The Meiji government that modernized Japan decided the direction which adopted western medicine positively and eliminated Oriental medicine, and carried out the policy to inhibit acupuncture (1874). However, there was no concrete system until 1885, when the Ministry of Home Affairs issued a report to entrust the permission and superintendance of acupuncture to each prefecture. On the other hand, modern education for the blind was begun in various parts of the country in 1878, and acupuncture was adopted as a vocational course. The Rakuzenkai Blind School began Anma and acupuncture in 1881, but in 1885 acupuncture was removed from the curriculum and put under the direct control of the Ministry of Education. The principal of the school, Ryokichi Yatabe, had doubts about this and sent a question to Tokyo Imperial University. The answer to it (1887) was to recognize acupuncture, and this recognition became an admission of the revival of acupuncture in the course of blind education and the basis of the thought in legislation for modern Japanese acupuncture. There is a high possibilty that the reply to Yatabe was influenced by the article of Sansaku Okumura (1864-1912), a blind man in Kanazawa City, which appeared in the 157th issue of "Iji Shimbun" (1885).

Acupuncture Therapy↗
PubMed2001

[Historical evidence of the beginning of modern medicine in the holy land: "list of medicinal preparations found in stores and dispensary on july 21st 1857"].

The London Society for Promoting Christianity Amongst the Jews established the first Western hospital in Jerusalem in the middle of 19th century. It was built for the benefit of the Jewish population of the city, and it transposed the Holy Land, from a medical point of view, to the modern era. The huge archives of the London Society in England contain many documents dealing with its activity. One document, revealed here for the first time, describes the content of the medicinal preparations held in the stores of the British hospital and dispensary in Jerusalem on July 21 1857. The list, presented here in full, is impressive in its length, containing hundreds of medicinal substances originating from plants, minerals, and animals that were used in the Western world at the time. Most of the chemicals in the list had never previously appeared in any published historical source concerning Palestine. The list is thus one of the first pieces of evidence of modern medical and pharmacological activities in the Holy Land. A comparison of the list with several other 19th century lists of medicinal substances found in professional literature revealed that it contains most of the known medicinal substances of that time. Compared with medieval documents, or lists of traditional substances compiled a few years earlier, the 1857 list is richer and contains new substances and preparations originating in the New World (America) and chemicals unknown in the region before. It is evidence of the change that occurred in the field of pharmacology owing to the penetration of the modern medicine into the Holy Land. The 1857 list contains 268 substances: 147 medicinal preparations of plant origin, 117 preparations of chemical and mineral origin, and only four of animal origin.

History, 19th Century↗
PubMed1975

Traditional medical practitioners among the Bambara of Mali and their role in the modern health care delivery system.

The Bambara of Mali, who are sedentary agriculturists, number about two million and are the most important ethnic group in the country. They are gradually being Islamized, but retain many animist beliefs. Their traditional medical care system possesses a heterogenous group of practitioners who have either an animist or an Islamic culture reference. The traditional medical care system of the Bambara was studied and an evaluation of the quality of its practitioners made on the basis of a survey conducted in 128 villages over an eight-year period. During the study, patients, traditional practitioners and modern health workers were interviewed and their attitudes towards one another recorded and analyzed. Certain categories of traditional practitioners have a definite constructive role to play in a modern health care delivery system. Others, however, have had a long history and high incidence of charlatanism. Legitimatization of these categories and their incorporation into the modern health care system is not recommended.

Attitude of Health Personnel↗
PubMedDate not supplied

Was Lysenko (partly) right? Michurinist biology in the view of modern plant physiology and genetics.

Soviet Lysenkoism was the darkest period of modern science, and its main product--Michurinist biology--was a collection of absurd theories usually based on anecdotal observations or on a few badly designed experiments without proper controls and without any statistical evaluation of results. However, in the thirties and early forties, Lysenkoists also described (and misinterpreted) some interesting data and observations which could have been real and which might inspire modern biologists to construct testable hypotheses and suggest experiments that could extend our scientific knowledge. Here, I attempt to present an explanation in terms of modern biology of some of those phenomena, namely vegetative hybridization, wobbled heritability, heritability of environmentally induced adaptive modifications and effects of intravariety hybridization of self-fertilizing cultivars. The first two phenomena can be explained on the basis of visualization of hidden genetic and epigenetic polymorphism (originating from somatic mutations, somatic recombination and paramutations), the third phenomenon by the occurrence of intraindividual selection of somatic cell lines, and the fourth phenomenon by low heritability of phenotypic properties (and therefore also low capability to evolve) of outcrossing organisms (in comparison with self-fertilizing or asexual organisms), i.e., by a theory of frozen plasticity.

Environment↗
PubMed2001

The relationship between prenatal care and subsequent modern contraceptive use in Bolivia, Egypt and Thailand.

Determinants of modern contraceptive use are usually examined in isolation of the effect of exposure to other aspects of health care systems. Maternal interaction with organised health service provision during post-conception and postpartum stages of reproduction can provide an opportunity to transfer contraceptive service information and counselling. We found that living in a community in which women have widespread health service contact is related to both prenatal care use and subsequent modern contraceptive use. After controlling for effects of living in high health service contact areas and various demographic and background factors, our results suggest that prior use of prenatal care has a strong influence on subsequent use of modern contraception in Bolivia, Egypt and Thailand.

Bolivia↗
PubMed2003

The toxic torch of the modern Olympic Games.

One of the most enduring symbols of the Olympics is the torch or flame, an icon of peace and sportsmanship that has its roots in Ancient Greece. According to the Creed of the Olympics: "The important thing in the Games is not winning, but taking part. The essential thing is not conquering. but fighting well." The modern Olympic Games (1896-2000) have been heavy laden with controversy, as athletes have abused performance enhancing drugs to thrust themselves into the limelight in search of gold. It was not until 1967 that the International Olympic Medical Commission began banning drugs. Full-scale drug testing was instituted in 1972.: Retrospective review of modern summer and winter Olympics Game sources (1896-2002) was done for documentation of drug abuse, drug-related overdoses, and positive drug screens. Data were collected for the type of drug documented. the athlete's name, their country of origin, and Olympic event. Seventy cases were identified. The most common class of agents were steroids (29), followed by stimulants (22), diuretics (7), beta-2 agonists (2), and beta blockers (1). Alcohol and marijuana, while not historically prohibited, have been outlawed by several individual sport federations. Toxicities of these 2 agents were most likely under-reported. Countries of origin of individual athletes included Bulgaria (7), USA (7), Sweden (4), Spain (4), Japan (2), Poland (2), Greece (2), Canada (2), Hungary (2), Russia (2), Austria (2), and Great Britain, Norway, Romania, Armenian, and Latvian, each with 1. The most common Olympic events in which drug abuse was documented were weightlifting (25), trackand field (12), skiing (5), wrestling (5), volleyball (3), modern pentathlon (3), cycling (2), swimming (2), gymnastics (1), and rowing (1). As athletic pressures and financial gains of the Olympic Games heighten, more toxicities are likely to occur despite attempts at restricting performance-enhancing drugs.

Adrenergic Agonists↗
PubMed2002

"With much nausea, loathing, and foetor": William Harvey, dissection, and dispassion in early modern medicine.

In early modern England accumulating knowledge of normal and morbid anatomy through dissecting the human body not only led to a better understanding of nature, but also defined the identity of the people who engaged in this activity. This essay analyses the relationship between systemically dismembering the dead and how this pursuit shaped the attitudes and emotions of early modern medical men toward the living. I focus on the most famous anatomist in early modern Britain - the discoverer of the circulation of the blood, William Harvey (1578-1657).

Anatomy↗
PubMedDate not supplied

[On the origins of modern science].

The Renaissance savants essentially repelled the scholastic translations and commentaries of the ancient writings. Nevertheless, they did not reach a modern vision of experimental science. Moreover, education at the universities was not credited for the development of science. In fact, academic training of students was rather precarious. The first professional associations, such as the "Royal College of Physicians" of London, were not any better. Regarding the hermetic influence on Renaissance thought, the cultured and philosophical reformed magic (so-called white magic) was the equivalent of science at the time. Once the animistic universe, operated by magic, was transformed into the mathematical universe operated by mechanics, the era of science came into being. This movement began during the post-Renaissance age and gradually progressed following the physical-mathematical orientation of Galileo and his pupils: Borelli; Fabrizi; Santorio; Harvey, etc. They initiated physiological studies and introduced the quantitative method into the research field. Harvey's doctrine was the first adequate explanation of an organic phenomenon and a starting point for the way toward experimental physiology. However, the English physician did not completely leave the pre-scientific era, as can be inferred from his monography on animals reproduction. In this work, some points suggesting the birth of modern scientific reasoning alternate with confused, vague, and capricious assertions. In fact, modern science did not arise suddenly, but was elaborated and sustained slowly starting in the XVII century: Galileo's century.

History, 16th Century↗