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PubMedDate not supplied

[Hunger and mental illness].

Based on a recently-published article on the triad of drought, hunger, and mental illness, in which the main idea is that destitution may be leading to behavioral disorders in the drought-plagued population of the Brazilian Northeast, we reflect on what this so-called 'madness' may represent for this group of people. We attempt to analyze the issue from various disciplinary perspectives, going beyond merely causal explanations and taking into account that the reported disorders entail meanings following the articulation of cognitive, affective, and experiential elements founded on the social and cultural relations of individuals. From this point of view, the respective discourse assumes other interpretations, showing that illness is a singular process of construction.

Brazil↗
PubMed1974

Hunger and contrast in a multiple schedule.

Pigeons working for food on a multiple variable-interval 1-min-variable-interval 4-min schedule were subjected to variations in body weight, presumably causing changes in hunger. The proportion of responses in each component approached and eventually reached the proportion of reinforcements as body weight increased. This effect follows from the matching-law interpretation of contrast in multiple schedules.

Animals↗
PubMed1998

Troglitazone reduces plasma leptin concentration but increases hunger in NIDDM patients.

OBJECTIVE: Troglitazone, which improves peripheral insulin resistance of experimental diabetic animals and diabetic patients, affects ob gene expression in the adipose tissue of rodents. The present study was undertaken to examine a hypothesis that clinical administration of troglitazone may reduce circulating leptin levels and affect eating behavior in NIDDM patients. RESEARCH DESIGN AND METHODS: Troglitazone was administered at a dosage of 200 mg twice daily for 12 weeks in 20 poorly controlled NIDDM patients. Chronological changes in glycemic control, serum lipids, immunoreactive leptin (IRL) levels, and BMI were measured. Body fat weight was also assessed by bioelectric impedance. RESULTS: Troglitazone significantly decreased fasting plasma glucose, serum immunoreactive insulin, and HbA1c levels. Serum levels of IRL and triglyceride were significantly reduced by troglitazone administered for 4, 8, and 12 weeks. Troglitazone administration significantly increased the BMI in NIDDM patients, and two-thirds of the patients complained of increased hunger after the start of troglitazone administration. CONCLUSIONS: Troglitazone significantly reduces circulating leptin levels at clinical doses. It may affect the eating behavior of poorly controlled NIDDM patients through the improvement of glycemic control and/or the reduction of circulating leptin.

Blood Glucose↗
PubMed2005

Preorbital gland opening in red deer (Cervus elaphus) calves: signal of hunger?

The opening of the preorbital gland in red deer (Cervus elaphus) calves has been hypothesized to be a signal to the mother that her calf is hungry. Closing of the gland should indicate that the calf has received a sufficient amount of milk, and thus the mother should stop the suckling. We tested the hypothesis that the calf signals hunger when its preorbital gland is open and signals satiation when the gland is closed. To test this, the behavior of eight bottle-reared calves was monitored for 6 mo. For each meal during this time period, opening of the preorbital gland was recorded before calves were offered the meal and after they ate. Satiation of the calf was estimated (not begging for more food after the meal = satiated; begging = not satiated). The data set contained 3,116 records of paired measurements of preorbital gland opening (before and after the meal). Calves were satiated after feeding for 90.15% of the meals. The opening of the preorbital gland was associated with feeding and achieving satiety. In most cases (77%), calves opened their preorbital glands before their meal. Eighty-five percent of hungry calves still had preorbital glands open after the meal, whereas preorbital gland opening was decreased (P < 0.03) up to 46.6% in satiated calves. Despite this, we found a large range in individual responses in preorbital gland opening before and after the meal, and also according to whether the calf reached satiety. The heavier calves in this study tended to have their preorbital glands open more frequently than the lighter ones, which may indicate the need for an increased amount of milk intake. There was no clear trend in the frequency of preorbital gland opening with age. In conclusion, preorbital opening is likely to be a signal of calf satiety, as suggested earlier. Nevertheless, preorbital glands were not always open when the calves were hungry and did not vanish during the feeding in all cases.

Age Factors↗
PubMed1976

[A non-receptive hunger].

The Psychopathology of Anorexia mentalis offers the main and singular interest to understand how hunger is a need and no aliementar response can suffice. The recent contributions of psycho-analysis give central significations of the food relation between mother and baby. The symbolic importance of this relation is determinant in the normal behaviour.

Anorexia Nervosa↗
PubMed2000

[Hunger tolerance of Microvelia horvathi hibernating generation].

The experimental results showed that the hunger tolerance (HT) of different wing forms Microvelia horvathi adults had significant difference at 14-32 degrees C, and decreased with increasing temperature, which was 32.10 and 29.58 days at 14 degrees C, and 9.46 and 7.82 days at 32 degrees C, respectively for apterous and pterygote adults. The HT of apterous adults was higher than that of pterygote ones, and females was higher than males with the same wing form. The lower the temperature, the bigger the difference. The HT of M. horvathi adults differed obviously with densities. 1 female 1 male per bottle had a higher HT than 5 females 5 males per bottle and 10 females 10 males per bottle, while no difference was found between two latter densities. The HT of the 1st instar nymphs of M. horvathi had an obvious difference at different temperatures, which was significantly higher at 14 and 20 degrees C than at 26 and 32 degrees C.

Animals↗
PubMedDate not supplied

[Daily sensation of hunger, before and after phototherapy, in subjects with depression-type seasonal affective disorder].

OBJECTIVE: The present study investigates the daily pattern of hunger sensation (HS) in women affected by "seasonal affective disorder--depression type" (SAD-DT), before and after therapeutic exposure to bright light (phototherapy). The aim is to detect whether there are disorders in daily HS during the active phase of the disease which can be normalized by an effective treatment of the depressive status, via phototherapy. MATERIALS AND METHODS: Volunteered for the study 4 women affected by SAD-DT, 32-58 years old (BMI: 17.8-29.6 Kg/m2); 10 clinically healthy women (CHW), 21-52 years old (BMI: 23 e 25 Kg/m2) were recruited as controls. Both of the SAD-DT patients and CHW were asked to compile the "orexigram", which was chronobiometrically analyzed by means of the 1. conventional statistical methods; 2. rhythmometric analysis; 3. spectral analysis. RESULTS: Before phototherapy, the SAD-DT patients were found to be characterized by an increased HS (hyperorexia), with the circadian rhythm of the orectic stimulus (OS) which is shifted in its acrophase, being prone to become "free running". After phototherapy, the SAD-DT patients were found to show a little insignificant decrease in their OS, which still maintains a delayed phase in its circadian rhythm as well as the tendency to be "free running". CONCLUSIONS: The pre-treatment findings suggest that the SAD-DT patients are affected by hyperorexia associated with a "phase-shift" for the circadian periodicity of their HS, which is prone to the desynchronization. Such a dyschronism reinforces the hypothesis that the SAD-DT may be pathogenetically sustained by a mechanism of "phase-shift". The post-treatment findings suggest that both the hyperorexia and dyschronism of the orectic circadian rhythm are uncorrected by the phototherapy, even though the SAD-DT patients seem to have had beneficial antidepressive effects from the therapeutic intervention. The persisting dyschronism indicates that the photic stimulus is not able to completely reset the biological clock of the suprachiasmatic nuclei, at least for the phasic modulation of the HS circadian rhythm. The orexigram, thus, could be enclosed among the clinical tools in order to assess the complete efficacy of the phototherapy in SAD-DP patients.

Adult↗
PubMedDate not supplied

Circadian rhythm of hunger sensation in patients affected by dysthymic disorder.

PURPOSE: The present study investigates the daily pattern of hunger sensation (HS), namely orexia, in patients affected by "Dysthymic Disorder" (DD). The aim is to detect whether there are changes in the circadian rhythm (CR) of HS, herein investigated as a "marker rhythm", that can reveal a dysfunction of the "circadian biological clock" (CBC). In such a circumstance, one could be authorised to suggest a resynchronizing therapy, via antidepressant chronizing drugs and/or morning exposure to bright light, as it is currently done in other types of human depression, having a documented dysfunction of the CBC. MATERIALS AND METHODS: Volunteered with informed consent for the study 6 women (age = 34-56 years; mean BMI = 22.7 +/- 4.8 kg/m2) affected by DD. 10 clinically healthy women (CHW, age = 21-52 years; mean BMI = 24.0 +/- 0.5 kg/m2) were recruited as the controls. Both of the dysthymic patients (DP) and CHW were asked to compile the "orexigram", which was chronobiometrically analyzed by means of the 1. conventional statistical methods; 2. rhythmometric analysis for the CR; 3. spectral analysis for the harmonic components of the orexigram. RESULTS: The DP were found to be characterized by a normal daily level of HS, with 1. the CR of the orectic stimulus to be preserved and well located in its acrophase, and 2. the spectrogram of the orexigram to be substantially well configured. CONCLUSIONS: The above-cited results suggest that the DP show no alterations in the HS marker rhythm that can be taken as an evidence for declaring that the DD is not characterized by a relevant dysfunction of the CBC. Lacking in particular a phase-shift in HS marker rhythm, it can be argued that the DD is an affective disorder for which a resynchronizing therapy (exposure to bright light or pharmacological chronizers) seems to be "a priori" not indicated.

Adult↗
PubMed2002

[Functional organization of myogenic pacemaker of the stomach in conditions of hunger and satiation].

In chronic experiments, we have studied electrical activity of muscles of the gastro-esophageal sphincter, small curvature, corpus and antrum of the stomach in conditions of hunger, food intake behaviour and satiation of the rabbits. The aim of this study involved particularities of the electrical activity of myogenic pacemaker zone of the stomach. It has been shown that function of myogenic pacemaker of the rabbit stomach is performed by smooth muscles of the small curvature of the stomach. Pacemaker properties of muscles of the small curvature of the stomach are performed in conditions of food intake behaviour and satiation.

Action Potentials↗
PubMed2004

[Standardising hunger: François Magendie's feeding experiments on a gelatin fare 1831-1841].

Although François Magendie's studies on the functional differentiation of the spinal nerves, on the maintenance of blood pressure, and on the circulation of the cerebrospinal fluid have been sufficiently considered in medical historiography, his physiological research on nutrition, carried out between 1831-1841, has hardly attracted attention. With several series of animal experiments, Magendie tried to answer the question whether a gelatine-based fare would be suitable for feeding the indigent people of Paris. Taking these experimental series as a specific historical example, an approach from sociological systems theory is proposed in order to analyse the relations between Magendie's hunger laboratory, the French Académie des Sciences, food industrialists, and health and military administrators. The historiographical relevance of this approach as well as its methodological limitations are discussed in this article.

Administration, Oral↗
PubMedDate not supplied

[The spectral characteristics of the electrical activity in the rabbit brain during the hunger dominant].

By means of daily alimentary deprivation the dominant of hunger was created in rabbits. In response to acoustic stimuli summational swallowing and chewing movements appeared. Spectral analysis of the electrical brain activity showed the presence of primary dominant focus zone (lateral and ventromedial hypothalamus), characterized by an increase of spectrum power in delta-range while in the orbito-frontal, sensorimotor, parietal cerebral cortex, in the medial and lateral preoptic hypothalamic zones the power of biopotentials spectrum decreased within the whole analyzed frequency range.

Acoustic Stimulation↗
PubMed1991

Changes in the responses of the neurons of the sensorimotor cortex to stimulation of the hunger centre of the lateral hypothalamus.

The responses of sensorimotor cortical neurons in hungry and in fed rabbits to stimulation of the lateral hypothalamic (LH) hunger centre were studied in the presence and absence of food. It was found that in the absence of food the response of the sensorimotor cortical neurons to LH stimulation differed between hungry and fed animals. No changes in firing rate were observed in 50% of neurons in hungry rabbits, and firing was inhibited in 45% of neurons in fed animals. Feeding reinforcement changed the nature of neuronal responses to LH stimulation. Qualitative changes in the responses to LH stimulation were observed in 77% of neurons in hungry rabbits, and in 61% of neurons in fed rabbits. Most neurons increased their rate of firing both in hungry and in fed animals.

Animals↗
PubMed1990

[Electric activity of striated muscles of the cervical part of the rabbit esophagus under conditions of hunger, food intake and satiation].

The experiments of free-moving rabbits have shown that the muscles of the proximal zone in the esophageal cervical part functions as the superior esophageal sphincter. In hunger stage the motor unit activity of the sphincter has regular low-amplitude discharge with monomodal distribution of interspike intervals. The process of food satisfaction leads to the appearance of burst-like unit activity with bimodal distribution of interspike intervals. During the food intake reorganization of the motor unit activity of the esophageal cervical part is manifested in characteristic patterns of interspike interval distribution.

Animals↗
PubMedDate not supplied

Weight gain in patients with breast cancer receiving adjuvant treatment as a function of restraint, disinhibition, and hunger.

Little is known about how/why women who receive adjuvant chemotherapy treatment, hormone therapy, or radiation for nonmetastatic breast cancer gain weight. This study's purpose was to use the restraint-disinhibition model to understand susceptibility to weight gain, and the potential impact of exercise and dysphoria. Data were collected using interviews, medical records, and standardized instruments (e.g., PAIS, BSI, EDI) at a mean of 19 months post-treatment onset for 73 subjects who received either chemotherapy, tamoxifen, or radiation after definitive surgery. The data were analyzed using MANCOVAs, stepwise logistic regression, correlation matrices, chi-squares, and descriptive statistics. Findings indicated that subjects who scored high on a measure of perceived hunger and who responded to external eating cues (disinhibited) tended to weigh more at baseline and be more likely to gain weight after therapy ended (p less than 0.05). Subjects who tended to control their weight (restrained) tended to gain weight during treatment and to stabilize once treatment ended (p less than 0.01). This study suggests that weight gain can be controlled by diet and exercise based on measurable dietary patterns.

Adaptation, Psychological↗
PubMed1987

Some evidence for short-term caloric compensation in normal weight human subjects: the effects of high- and low-energy meals on hunger, food preference and food intake.

This study compared the effects of high- and low-energy lunches upon subjective motivation to eat and food intake. Subjects ate four cooked lunch-time meals on separate days, two of which were high-energy (1820 kJ or 435 kcal) and two low-energy (1090 kJ or 260 kcal). The meals were of similar bulk, contained similar amounts of protein and carbohydrate but different fat contents, the low-energy meals containing very little. Motivational ratings and food preference assessments were completed before, and at hourly intervals for 3 h after the meals during which time subjects were not allowed to eat. Food intake diary records were kept for the rest of the day. Immediately after consumption of the meals none of the ratings differentiated between the high- and low-energy meals. At 1 h rated hunger was significantly higher after the low-energy meal and by 3h high- and low-energy meals were significantly differentiated by almost all measures. When subjects were allowed to eat freely, food intake records showed that energy intake was higher following the low-energy meal during the first 2 h but was lower thereafter. At the end of the assessment period (i.e. 8h after lunch) subjects had made a statistically non-significant 43 per cent compensation for the energy 'lost' at lunch. These findings are of theoretical importance since they provide evidence of short-term monitoring of energy. This study is of practical significance since it discloses certain consequences of using reduced energy foods which may form part of a weight control programme.

Adult↗
PubMed1984

Contributions of reduced hunger and premature satiety to cancerous hypophagia in rats.

Tumor-induced reduction in food intake in 2 rat-tumor organisms was distributed approximately equally between reduction in average size (premature satiety) and reduction in frequency (impaired perception of hunger) of effective meals. In both organisms, the frequency of futile meals (activity at food dish without any food ingestion) increased in the tumor-bearing state, and total meal frequency (effective plus futile meals) was unchanged from the tumor-free state. It is proposed that the presence of tumor reduces some meals to zero size and that satiety can occur in the cephalic phase of digestion before any food has been ingested. By this interpretation, cancer hypophagia would be entirely attributable to premature satiety.

Animals↗
PubMedDate not supplied

Hunger versus hoarding and body weight in rats.

The present study revealed that the rats kept on two hour meal schedule hoarded large quantity of food as compared to their hoarding score when kept on food ad lib. Body weights were maintained even though the food intake was slightly reduced. Hunger seems to a stronger drive for hoarding.

Animals↗
PubMed1994

[Radiology in the 3d World, illness, hunger, violence].

Parasitoses, perinatal X-ray diagnostics, hunger, war, and torture produce X-Ray findings that are hardly known in Western and Central Europe. X-ray diagnostics in the 3rd world are often decisive for the diagnosis due to the lack of other methods. X-ray diagnostics offers many possibilities but is often not available or available only for few.

Adolescent↗