Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “FIBROMA”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 397 records · Page 22Linked to original sources

Nevoid basal cell carcinoma syndrome: bilateral ovarian fibromas in a 3 1/2-year-old girl.

A 3 1/2-year-old black girl with bilateral ovarian fibromas was subsequently diagnosed as having nevoid basal cell carcinoma syndrome at the age of 4 years, when basal cell tumors and pits of the hands and feet were noted on examination. This case is unusual because of the development of bilateral ovarian fibromas at an extremely early age. Prepubertal patients with this ovarian tumor should be thoroughly investigated for the possibility of nevoid basal cell carcinoma syndrome.

Basal Cell Nevus Syndrome↗

Collagenous fibroma (desmoplastic fibroblastoma).

Collagenous fibroma (desmoplastic fibroblastoma) is a recently described tumor that may arise in the subcutaneous tissue or skeletal muscle. We report a case of collagenous fibroma, occurring on the forehead of a 67-year-old man. An awareness of this entity is necessary to avoid confusion with other soft tissue neoplasms, especially extraabdominal fibromatosis.

Aged↗

Recurrent desmoplastic fibroma.

Two cases of recurrent desmoplastic fibroma are reported and the relevant literature reviewed. In both cases the original lesion was incompletely removed more than 10 years previously and the slow but aggressive spread of the recurrences is documented. Desmoplastic fibromas are locally invasive tumors and primary surgical excision should be accomplished together with a margin of normal tissue. The second case also presented with an associated amputation neuroma and this topic is briefly discussed.

Adult↗

Ossifying fibroma of the jaws. Review of the literature and report of 16 cases.

Ossifying fibroma is a fibro-osseous lesion rarely occurring in the jaws, although more often than in other bones of the skeleton. It is not clear whether it represents a distinct entity or a certain stage of the fibro-osseous condition. We are presenting our experience with 16 cases of ossifying fibroma treated with local excision or resection and bone graft. Their radiographic picture varied significantly from one case to another. One case was peripheral and one recurred.

Adolescent↗

Desmoplastic fibroma of the mandible: case report.

This report describes the case of a 2-year-old girl with desmoplastic fibroma of the mandible, with swelling in the region of the mandibular angle which had been wrongly diagnosed several times. A biopsy was interpreted as showing a low-grade fibrosarcoma. The patient then received treatment with cytotoxic drugs, and later a mandibular hemi-resection was performed. The postoperative diagnosis was Jaffé's desmoplastic fibroma (non-osteogenic). The age of the patient, the rapid development of the tumour and the accompanying pain suggested a sarcoma, and the first pathological examination seemed to provide confirmation. The post-operative course was very favorable, and the patient is considered to clinically cured, after one year.

Child, Preschool↗

Trichoblastic fibroma (fibromatoid trichoepithelioma).

Six examples of so-called trichoblastic fibroma occurred in five females and one male. The age of the patients ranged from 46 to 70 years (mean: 61 years). Three tumours were on the back, one each on the left gluteus, right skull and left thigh; they were present one to 20 years and varied in size from 1.8 to 6 cm. The tumour nodules were easily shelled out at operation, and the macroscopic aspect was that of fibroma. Although there seems to be a close relationship to trichoepitheliomas, this tumour deserves a separation from classical conventional trichoepitheliomas and differs from these by size, consistency, involvement of deeper tissues, nodular character, unusual location, age of patients and additional histopathologic findings. In our opinion, these rare tumours may also be classified as fibromatoid trichoepitheliomas.

Aged↗

Juvenile aponeurotic fibroma with disseminated fibrosarcoma.

Juvenile aponeurotic fibromas, although locally recurrent, generally do not metastasize. This observation supports the practice of incomplete excision of the tumor to preserve the function of the involved extremity. We report on a patient with a juvenile aponeurotic fibroma of the palm, who returned 5 years after the second local surgical excision with metastatic fibrosarcoma of the lungs and bones.

Adipose Tissue↗

[Clinical aspects and diagnosis of pleural fibromas].

Pleural fibromas are rare malignant or benign tumors requiring pathology study for certain diagnosis. From January 1985 to January 2001, 7 patients underwent surgery in our unit for pleural fibroma: 4 females and 3 males, mean age 60 years. The inaugural symptoms were chest pain (3 patients), dyspnea (2 patients), joint pain in a patient with Pierre-Marie pneumonic hypertrophic osteo-arthropathy, and acute hypoglycemia. Radiological investigations were decisive in orienting the diagnosis (chest X-ray, ultrasound, computed tomography and MRI). Surgical resection and pathological study of the surgical specimen is required to confirm the diagnosis. Patients should be carefully followed due to the risk of malignant recurrence.

Adult↗

Fibroma of the vulva.

We describe a patient with fibroma of the vulva. The tumor had areas of marked hypointensity consistent with fibrosis on T1 and T2 weighted magnetic resonance (MR) images. The presence of abundant fibrous tissues on MR images enabled us to make a preoperative diagnosis of fibroma.

Adipose Tissue↗

Desmoplastic fibroma of bone: case report.

Desmoplastic fibroma of bone is an exceedingly rare tumor that was first described by Jaffe in 1958 [1]. It has a high incidence of local recurrence after surgical resection. It is usually seen in young patients and involves mandible and long bones. It has histological resemblance to the desmoid tumor of the abdominal wall. We report a surgically proven case of desmoplastic fibroma of bone with local aggressiveness and recurrence during follow-up. The radiograph, CT imaging features, radiological and pathological differential diagnosis of the case are described, and literature is briefly reviewed.

Adult↗

Giant ossifying fibroma. Case report on a bimaxillary presentation.

Ossifying fibroma is a slow-growing, benign neoplasm, but some lesions behave aggressively, reaching massive proportions, thus demanding special treatment. The following case report holds particular interest, because of the simultaneous occurrence of an active ossifying-cementifying fibroma in the maxilla and mandible with the maxillary lesion attaining enormous size.

Adult↗

True fibroma of the oral mucosa: a case report.

A case of true fibroma of the maxillary alveolar mucosa in a 44-year-old woman is reported. The clinical and histologic criteria for its distinction from irritation fibroma are discussed.

Adult↗

Odontogenic fibroma in Sprague-Dawley rats: a report of 2 cases.

Two cases of odontogenic fibroma occurring in aged Sprague-Dawley rats are described. Both neoplasms were associated with a maxillary incisor and had identical histomorphological features. They were composed of solid proliferations of primitive, dental pulp-like mesenchyme separated by areas of collagenization. Small strands and islands of mainly undifferentiated odontogenic epithelium immunostaining for keratins were scattered throughout both tumours. As a further characteristic, the lesions contained small foci of mineralization which were either cementum-like or resembled dysplastic dentin. The odontogenic fibroma represents a further type of odontogenic tumour in rats, which due to its typical histomorphology, can easily be differentiated from other odontogenic tumours such as ameloblastic odontoma or ameloblastoma.

Ameloblastoma↗

Intra-articular fibroma of tendon sheath in the temporomandibular joint.

Fibroma of tendon sheath is an uncommon soft tissue tumor. The first case involving the temporomandibular joint is reported here. The patient presented with chronic clicking, pain, and swelling of the right temporomandibular joint associated with restricted jaw opening. Histologic, immunocytochemical, and ultrastructural features of the intra-articular tumor were identical to fibroma of tendon sheath. The variability of symptoms and the diagnostic problems presented by this tumor are discussed.

Actins↗

Fibrous dysplasia and ossifying fibroma of the paranasal sinuses.

Fibro-osseous lesions involving the paranasal sinuses, the mid-face and anterior skull base are uncommon. In addition, there appears to be no clear pathological or clinical classification that embraces the variety of lesions that exhibit such diverse pathological and clinical behaviour, yet may still be referred to as a fibro-osseous lesion. The diagnosis of fibrous dysplasia and ossifying fibroma is made on a combination of clinical, radiological and pathological criteria. This paper emphasizes the clinical and pathological differences between fibrous dysplasia and ossifying fibroma. The more aggressive clinical behaviour of the latter is highlighted and a more radical surgical approach is recommended. In contradistinction, fibrous dysplasia can exhibit a more benign behaviour and radical surgery is not always justified. A clinicopathological distinction between these two conditions is important from a management perspective despite the fact that they both may be encompassed under the 'umbrella' term fibro-osseous lesion.

Adolescent↗

Ossifying fibroma of the mandible with primary hyperparathyroidism due to non-familial parathyroid adenoma.

Ossifying fibroma is an uncommon benign osteogenic neoplasm arising from cells of the periodontal ligament, typically with a slowly progressive enlargement of the affected bone. The neoplasm sometimes presents with hyperparathyroidism, most of which cases are due to familial parathyroid tumours. We report a rare case of ossifying fibroma of the mandible which showed very rapid growth and presented with primary hyperparathyroidism due to non-familial parathyroid adenoma. Despite improvement of parathyroid dysfunction after removal of the parathyroid adenoma, the tumour continued to grow very aggressively. The case required partial mandibular resection for complete resection of the tumour, and fixation of the remaining mandible with a titanium plate.

Adenoma↗

Giant fibroma of the right ventricle.

Cardiac fibromas are rare benign tumours of connective tissue that occur most frequently in children within the left ventricle. Spontaneous regression has not been observed, and surgical intervention is usually required. We have successfully treated a 1-year old girl with a giant fibroma of the right ventricle using the principles of the Batista procedure. The diagnosis was primarily made using transthoracic echocardiography.

Cardiac Surgical Procedures↗