Destination unforeseen: the birth of the research-intensive pharmaceutical industry
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In continuation of preceding investigations, in 184 duck embryos of the developmental stages 18-27 according to Hamburger and Hamilton (about 85-140 hours of incubation) a study was done on the occurrence of median germ cells. These cells proved to be present in proportionally small numbers in the stages 19-26. Their numbers were independent of the sex of the embryos and did not show any relations whatever with changes in the numbers or distribution of the intragonadal germ cells. The temporary occurrence of the median germ cells could be shown to be due to the movement of the gonadal primordia from the splanchnopleure of the yolk sac to the ventro-medial surface of the mesonephros, and it was argued that ultimately all these germ cells reach the right of left gonad.
The movement of young adults with special health care needs from pediatric-oriented care to adult-oriented care has been a growing concern in the health care literature over the past 20 years. This article reviews the development and evaluation of health care transition policy over that period of time. These health care transition policies are discussed in light of the preliminary results from a qualitative study of the experience of health care transition. This article concludes with suggestions regarding future policy development and research efforts around health care transition.
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This article discusses the integration of the latest technologies into the dental practice. Given the rapid rate of obsolescence in computer hardware, clinicians need to look to practice-management software to build the foundation for incorporating all future applications into a smoothly running operation. Combined, the core components of the clinical dental record, digital radiography, intraoral and digital cameras, and cosmetic imaging create an integrated dental image-management system that is becoming a critical factor in how we communicate with our patients and with each other.
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