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Dermatoglyphic peculiarities in hypospadias.

The digital and palmar dermatoglyphics of 33 children with hypospadias were studied. Compared to a control group of 620 normal males the children with hypospadias showed the following statistically significant differences: (1) A lower frequency of whorls and a higher frequency of ulnar loops on fingers (32.4% whorls and 60.0% ulnar loops vs. 42.4% whorls and 50.2% ulnar loops in controls); (2) a high frequency of individuals with hypothenar radial loops on both palms (24.2 vs 8.8% in controls); (3) a high percentage of pairs of homologous fingers with the same pattern type on both fingers (82.4 vs. 73.3% in controls), and (4) an increased degree of bilateral symmetry of finger ridge counts (A, a measure of the asymmetry of ridge counts on homologous fingers, is 6.52 vs 8.08 in controls).

Child↗

Dermatoglyphics in unipolar depression. Relevance of family history.

Qualitative dermatoglyphic features have been studied in 120 patients with unipolar depression and analysed with special reference to the presence or absence of similar cases in the close relatives. Significant differences were observed between the two groups of patients which give support to the assumption of aetiological heterogeneity between isolated and familial cases.

Depressive Disorder↗

Further studies on the genetics of the Chamorros of Guam: dermatoglyphics.

The present study represents a continuation of our efforts to further define the genetic structure of the Chamorro population of Guam. The dermatoglyphic features of Guamanian Chamorros differ significantly from those of Western Carolinians from the Outer Islands of Yap in fingerprint patterns, model types of C line, frequency of patterns in the thenar/I area and in the presence of Sydney creases. The results of this analysis confirm earlier data from serological and other genetic markers that Guamanian Chamorros are genetically more closely related to the people of southeastern Asia than to their Micronesian neighbors to the south.

Adult↗

A dermatoglyphic study of the Gurungs, Mangars and Kirantis of Nepal.

Finger and palm prints were collected from 306 Nepalese males belonging to the Kiranti, Gurung and Mangar tribes of Nepal. The dermatoglyphic characteristics show affinities with other Asiatic Mongoloid populations especially those residing in the southern Himalayas.

Asian People↗

Dermatoglyphic patterns and pattern intensities of Callicebus (primates: Cebidae): description and comparison of three species.

The palmar and plantar dermatoglyphic pattern types are described for three species of Callicebus (18 Callicebus moloch, 18 Callicebus torquatus and 7 Callicebus personatus). Mean pattern intensities (API) were calculated for each of seven areas of the palm and nine areas of the sole, and a summed mean total pattern intensity (TPI) for each volar surface. Nonparametric statistical testing showed no significant bilateral asymmetry or sexual dimorphism in pattern intensities. Pattern profiles describing the relative relationships of API values across the left palm and sole are presented. The profiles typical of the genus closely resemble those of Aotus and Saimiri. Significant interspecific differences, particularly in the plantar API values, were detected. The results are discussed with reference to the present taxonomic classification of the species of Callicebus and their postulated evolutionary history.

Animals↗

Prenatal psychological stress, dermatoglyphic asymmetry and pregnancy outcome in the pigtailed macaque (Macaca nemestrina).

The relationships between maternal psychosocial stress during pregnancy and asymmetry in dermal ridge count, gestation length, birth weight percentile and survival were examined in 68 pigtailed macaque offspring. Twenty-five pregnant females were stressed daily by capture from 30 through 130 days postconception; 43 control unstressed females were housed under conditions of minimal disturbance. The difference between total intercore dermal ridge counts between right and left hands of the offspring was used as a measure of the perturbed development that theoretically occurs in the presence of a prenatal stressor. Dermatoglyphic asymmetry was significantly higher in the stressed offspring than in the unstressed group (mean asymmetry = 7.3 +/- 2.8 and 5.4 +/- 2.5, respectively; t = 2.85, p less than 0.01). Although maternal stress alone was not related to differential gestation length, birth weight, or survival, high asymmetry (8-13 residual dermal ridges) was significantly associated with increased perinatal mortality.

Animals↗

Dermatoglyphic asymmetry in fetal alcohol syndrome.

The hypothesis was tested that prenatal alcohol exposure disrupts developmental homeostasis, as reflected in increased dermatoglyphic fluctuating asymmetry. Twenty-two patients with fetal alcohol syndrome (FAS) and 9 with fetal alcohol effect (FAE) were matched for sex with 31 controls. On each patient, the right a-b dermal ridge count was subtracted from the left to obtain the asymmetry value. Group differences were tested by analysis of variance (ANOVA), and paired two-tailed t tests. Mean asymmetry increased from control (1.94) through FAE (2.78) to the FAS (4.00) group. Group differences were significant by ANOVA (p = 0.0066); only the FAS and control group differed by t test (p = 0.0025). The results support the hypothesis of increased decanalization of prenatal development in the presence of alcohol.

Adolescent↗

Congenital dermatoglyphic malformations and psychosis: a twin study.

OBJECTIVE: In a previous twin study, congenital dermatoglyphic abnormalities, such as ridge dissociations and abnormalities of palmar flexion creases, were more prevalent in twins with psychotic and related disorders than in comparison twins. This study was an attempt to replicate that finding in an independent study group. METHOD: Ridge dissociations and abnormal palmar flexion creases were assessed in monozygotic pairs concordant (19 pairs) and discordant (31 pairs) for psychosis and related disorders. RESULTS: The presence of either ridge dissociations or abnormal palmar flexion creases was higher in the combined group of affected concordant and discordant twins (37.7%), than in the nonaffected discordant twins (20.0%; odds ratio=2.4). In the discordant pairs, the presence of either abnormality was strongly associated with psychotic disorder (odds ratio=3.0). CONCLUSIONS: Factors affecting early fetal development may increase the risk for psychotic disorder. Differential exposure to such early risk factors may contribute to twin discordance for psychotic disorder.

Cross-Cultural Comparison↗

Dermatoglyphics and the persistence of 'Mongolism'.

In 1961, a prestigious group of medical researchers called on their colleagues to stop using the language of 'Mongolism' to describe people with what we now call 'Down's syndrome' (or Trisomy 21). This call responded to new knowledge about the biological basis of Down's syndrome: rather than the product of racial degeneration, as had been hypothesized in the 19th century, the condition was the result of an extra chromosome, dubbed '21'. Yet, despite this plea, the terms 'Mongol' and 'Mongolism' continued in scientific use through the 1960s. Drawing on published and archival materials, I argue that the new knowledge about chromosomes did not rupture older patterns of scientific practice or interpretation, and with them, older terminological habits. The persistence of the language of Mongolism reflects the continuity of a network of older approaches to interpreting the condition within the community of human and medical geneticists, including an enduring diagnostic and interpretive technology, dermatoglyphics. Old networks were not supplanted; they were re-aligned.

Dermatoglyphics↗

Dermatoglyphics in schizophrenia: the relevance of positive family history.

In the present study dermatoglyphic features were studied in schizophrenics with and without positive family history of schizophrenia. It was found that the difference between normals and schizophrenics was further exaggerated in those schizophrenics with a positive family history for schizophrenia. The implications of the findings and the need for further work are highlighted.

Dermatoglyphics↗

Manic-depressive psychosis and schizophrenia: a dermatoglyphic study.

The study analysed qualitative and quantitative dermatoglyphic features in schizophrenia and manic-depressive psychosis. Differences were found which support the view that these two psychoses are genetically distinct. A possible field for further study is discussed.

Bipolar Disorder↗

Comparative analysis of dermatoglyphic traits in Hungarian and Gypsy populations.

We examined dermatoglyphic prints of children in 11 Hungarian and 5 Gypsy population samples (collected from 1,998 children). We compared Hungarian and Gypsy populations based on 22 finger and 24 palmar traits. In univariate comparisons the two ethnic groups differed significantly in half of the studied variables (9 finger and 14 palmar traits). We used several types of multivariate analyses of the studied traits to separate the population samples. Homogeneity analysis and discriminant analysis proved to be the most appropriate method to distinguish the populations, whereas a principal components analysis was less adequate. Multivariate analyses were conducted separately for both finger and palmar traits. Although the differences between the populations were more pronounced for palmar traits, in our study Hungarian and Gypsy populations showed the best separation when finger and palmar traits were combined for analysis, except in the principal components analysis. As expected, the Hungarian and Gypsy populations separated definitely in most statistical analyses; the main reason for this is the different origins of the two ethnic groups. The existence of the difference also shows that admixture between Hungarians and Gypsies has been small despite their living beside one another for several centuries.

Adolescent↗

Genetics of dermatoglyphic asymmetry in Vaidyas of West Bengal, India.

In this study of the genetics of dermatoglyphic asymmetry, we collected bilateral finger and palm prints of 824 individuals from 200 families including 2 generations from an endogamous caste (Vaidya) in Barasat, North 24-Parganas District, West Bengal. Two main types of asymmetry (fluctuating asymmetry and directional asymmetry) were calculated between the two hands. The study includes familial correlation between first-degree relatives, principal-components analysis, and maximum-likelihood-based heritabilities (by pedigree analysis). We found, first, that familial correlations in all possible pairs of relationships (except spouse correlation) were weak but positive; some were even statistically significant. No indication of assortative mating was observed, but the influence of maternal environment could not be discarded. The results also showed that X-chromosome linkage does not seem to be involved. A second major finding is that five principal factors could be extracted from all these asymmetric traits, explaining 74.207% of the overall cumulative variance. Asymmetry of finger and palmar areas were clearly separated by factor. In addition, the heritabilities of the extracted five factors were in the range of 8-24%. These estimates are in agreement with some previously published data. The heritabilities of the factors describing palmar asymmetry are slightly lower than those describing finger asymmetry. The present results support the hypothesis that both types of asymmetry have a genetic basis and are influenced by the intrauterine environment.

Dermatoglyphics↗

Hypohidrotic ectodermal dysplasia: dental, clinical, genetic and dermatoglyphic findings of three cases.

Patients with hypohidrotic ectodermal dysplasia (HED) are characterized by the clinical manifestations of hypodontia, hypohidrosis, hypotrichosis and a highly characteristic facial physiognomy. This disorder is inherited as an X-linked trait. This report presents three cases with HED in which the clinical evaluation (intraoral and radiological), genetic findings and SEM examination of hair. Boys 6 to 14 year old and a 11 year old girl were referred to the Marmara University, Faculty of Dentistry, complaining of oligodontia in the maxillary and mandibular arches and delay in eruption of other teeth. Peg-shaped teeth have been observed. The dermatoglyphs of the patients were striking. SEM examination of hair demonstrated a distinctly abnormal longitudinal grooving along the entire length of each hair and a desquamation of the surface cuticles. The treatment was planned in a multidisciplinary odontological group involving pediatric dentistry, orthodontics, prosthodontics and oral surgery and maxillofacial radiology of future dental habilitation. A specially designed overdenture, a removable prosthesis and osseointegrated implants were constructed. Periodic recall visits were advised, to monitor the dentures and implants during periods of growth and development, and eruption of the permanent teeth.

Anodontia↗

[Results of dermatoglyphic studies in the Roussy-Lévy syndrome].

Dermatoglyphics performed on the three persons with fully developed RLS as well as on those with partial symptomatology revealed a striking agreement as to their pappilary systems and the characteristic deviation from the norm: irregularities on the pattern of the ridges of the finger and toe prints and on the soles and palms, a much reduced "total ridge count" (TRC), predominant bow patterns on the toe prints, grid-and reticularpatterned white lines on the soles and palms, loop proliferation on the soles and special shapes of the transverse palmar crease.

Child↗