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The effect of a therapy dog on the communication skills of an adult with aphasia.

UNLABELLED: Little evidence-based research has been published within the field of communication disorders on the role of dogs as catalysts for human communication. This single participant study, a point of entry into this realm of research, explores the effects of a therapy dog on the communication skills of a patient with aphasia receiving intensive speech and language therapy within a rehabilitation setting. The researchers conclude that the presence of the dog does have the potential to stimulate both overt social-verbal and social-nonverbal communication. LEARNING OUTCOMES: As a result of this activity the reader will be able to (1) describe the beneficial role of dogs to serve as catalysts for human communication (2) describe ways in which a person with aphasia may be assisted by a therapy dog and (3) become familiar with an animal-assisted therapy (AAT) program set-up for patients with communication disorders within a rehabilitation setting.

Affect↗

The consultive model with computers. An innovation in service delivery.

As the field of communication disorders continues to evolve, it must look beyond itself to bring together all the resources available in a community to maximize the process of remediation. The consultive model effectively does this by extending the amount of stimulation and feedback available to the client. The addition of the computer to the process provides a structure for agents of change that can be controlled by the supervising clinician. The computer also enhances accountability and improves report-generation capabilities. Although there are still many factors to consider, the consultive model using computers promises to be an efficient, effective service delivery system for the treatment of communication disorders.

Child, Preschool↗

A tutorial on conducting meta-analyses of clinical outcome research.

Throughout the educational, medical, psychological, and social sciences, meta-analysis is the present-day, broadly accepted means for combining many quasi-experiments in a synthesis for the purpose of establishing the weight of scientific evidence bearing on a certain research question. Meta-analysis thereby is the preferred method for determining the preponderance of evidence in clinical-outcome research relating to questions of treatment efficacy and treatment effectiveness. Relatively few meta-analyses appear in the literature of the communication disorder sciences. The purpose of this tutorial is to enhance the familiarity and accessibility of this technology in the domains of audiology and speech-language pathology. The results of the accompanying example constitute a preliminary meta-analysis of patient-perceived treatment effectiveness. The substance of the tutorial, however, transcends disciplinary interests regarding types of communication disorder.

Communication Disorders↗

Defects of intergenomic communication: autosomal disorders that cause multiple deletions and depletion of mitochondrial DNA.

Depletion and multiple deletions of mitochondrial DNA (mtDNA) have been associated with a growing number of autosomal diseases that have been classified as defects of intergenomic communication. MNGIE, an autosomal recessive disorder associated with mtDNA alterations is due to mutations in thymidine phosphorylase that may cause imbalance of the mitochondrial nucleotide pool. Subsequently, mutations in the mitochondrial proteins adenine nucleotide translocator 1, Twinkle, and polymerase gamma have been found to cause autosomal dominant progressive external ophthalmoplegia with multiple deletions of mtDNA. Uncovering the molecular bases of intergenomic communication defects will enhance our understanding of the mechanisms responsible for maintaining mtDNA integrity.

Chromosome Disorders↗

Emerging issues in Israel: commentaries in a global context.

Communication disorders in Israel is a well-established professional field, requiring academic training and dual certification in speech pathology and audiology. Entry level is a BA in communication disorders (comparable to a MA degree in the USA) and 1 year of work under supervision. It is possible to continue studies towards higher degrees (MA and PhD). We face the same problems as in the rest of the world with need for trained professionals in the social services and the need to deal with multilingual and multicultural issues.

Audiology↗

Support of programs for the communicatively disadvantaged child: role of the private foundation.

In comparison to its support of life-threatening diseases, the Federal government has given little support to preventing and alleviating communicative disorders. The very fact that they are not life threatening, means that communicative disorders can remain an uncomfortable, costly, and debilitating factor throughout the lives of millions of children and adults. In view of the magnitude of the problem and the lack of Federal support, responsible leaders are going to have to turn to the general public for support. Foundations, corporations and individuals can provide support for training and organizing services. Such support may well provide them with an opportunity to assist in an area which has touched their families or them personally. Research, training and service programs for the communicatively disadvantaged child are urged to seek financial support from private foundations.

Academies and Institutes↗

The Neurological Information Network.

The Neurological Information Network (NIN) of the National Institute of Neurological and Communicative Disorders and Stroke (NINCDS) was a loosely structured assemblage of a variety of information-transfer activities that existed for approximately 20 years, starting in the early 1960s. These activities included the Neurosciences Research Program at the Massachusetts Institute of Technology, the Parkinson's Disease Information Center at Columbia University, the Brain Information Service at UCLA, the Information Center for Hearing, Speech, and Disorders of Human Communication at the Johns Hopkins Medical Institutions, the Clinical Neurology Information Center at the University of Nebraska, the Cerebrovascular Disease Abstracts generated at the Mayo Foundation and appearing in the journal Stroke, and Epilepsy Abstracts published by Excerpta Medica. The article discusses primarily the sociopolitical factors that govern the creation and life of activities of the type enumerated.

Information Centers↗

Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): a disease of two genomes.

BACKGROUND: Mitochondrial encephalomyopathies are clinically and genetically heterogeneous because mitochondria are the products of 2 genomes: mitochondrial DNA (mtDNA) and nuclear DNA (nDNA). Among the mendelian-inherited mitochondrial diseases are defects of intergenomic communication, disorders due to nDNA mutations that cause depletion and multiple deletions of mtDNA. REVIEW SUMMARY: Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive disorder of intergenomic communication and is defined clinically by 1) severe gastrointestinal dysmotility; 2) cachexia; 3) ptosis, ophthalmoparesis, or both; 4) peripheral neuropathy; and 5) leukoencephalopathy. Skeletal muscle biopsies of patients have revealed abnormalities of mtDNA and mitochondrial respiratory chain enzymes. The disease is caused by mutations in the thymidine phosphorylase (TP) gene. TP protein catalyzes phosphorolysis of thymidine to thymine and deoxyribose 1-phosphate. In MNGIE patients, TP enzyme activity is reduced drastically, and plasma thymidine and deoxyuridine are elevated dramatically. We have hypothesized that alterations of nucleoside metabolism cause an imbalanced mitochondrial nucleotide pool that leads to depletion and deletions of mtDNA. CONCLUSIONS: MNGIE is a recognizable clinical syndrome caused by mutations in TP. The diagnosis can be confirmed by measuring TP activity in buffy coat or plasma levels of thymidine and deoxyuridine. Reduction of circulating thymidine and deoxyuridine in MNGIE patients may be therapeutic.

Adolescent↗

The NIDCD's clinical trials cooperative groups: a brief overview.

The National Institute on Deafness and Other Communication Disorders (NIDCD) embarked on the establishment of two clinical trials cooperative groups in October 1996 in response to a scientific research need. It intended that the clinical trials cooperative groups (CTCGs) design and implement clinical trial protocols capable of addressing the efficacy of therapeutic interventions for diseases and disorders of human communication. Most commonly, owing to the substantial number of patients required, the trials are expected to involve multiple study sites, with each study site adhering to a uniform study protocol, standardized treatment regimens, and prescribed data collection procedures. A complex administrative structure is required to coordinate the activities of the CTCGs and to assure compliance with a myriad of government regulations. Similarly, participating study sites must meet stringent requirements including leadership by an individual experienced in clinical trials. There is a relative dearth of experienced clinical trialists dedicated to research in human communication. This article details the complexities involved in the conduct of multicenter clinical trials and the NIDCD's efforts to promote clinical trials activities and to develop clinical trials training opportunities.

Clinical Trials as Topic↗

[Psychology, audition and language in different disorders of childhood. Communication and neuropsychological aspects].

INTRODUCTION: A great number of language problems in children are related to neurological lesions in the central nervus systems. DEVELOPMENT: Cerebral palsy is one of the lesions more frequent. In many occasions the neurological alteration is accompanied by transmission hypoacusies, language delay an dysarthric problems in speech and voice. Moreover some of these cases have difficulties in attention, slow in speed of processing information, and different executive capacity depending on neurological and context factors. This work focuses into the aspects to consider the observation, evolution and treatment of these patients.

Brain↗

Voice and resonance disorders in genetic syndromes: a meta-analysis.

It is well known that many genetic syndromes are associated with communication disorders and especially with disorders of voice and resonance. This paper reports the results of a meta-analysis with the aim of documenting the occurrence of voice and resonance disorders in genetic syndromes. The analysis studied the occurrence of voice and resonance disorders in general, the occurrence in different etiological subtypes of syndromes and the association with other disorders, in particular clefting, a cognitive impairment and hearing problems. The database for the analysis was a list by Sphrintzen of 299 different syndromes all of which have been reported to entail communication disorders. Major findings are that disorders of voice and resonance in genetic syndromes are only rarely isolated problems, that causal mechanisms are not a major factor in determining the presence of voice and resonance disorders and, foremost, that voice and resonance disorders in genetic syndromes constitute an underresearched area.

Cognition Disorders↗

Perseveration and other repetitive verbal behaviors: functional dissociations.

This article will review types of perseveration from a neurolinguistic perspective. During the course of the article, continuous, stuck-in-set, and recurrent perseveration will be placed in contradistinction to several other types of repetitive behaviors commonly associated with neurogenic communication disorders. These include echolalia in mixed transcortical aphasia; conduite d'approche and conduite d'ecart in fluent aphasias; lexical and nonlexical automatisms in nonfluent aphasias; palilalia in neuromotor disorders, such as Parkinson's disease (PD); and sound, syllable, word, and phrase repetitions in neurogenic stuttering. When differentiating these phenomena from perseveration, it is helpful to consider the salient factors that condition observed behaviors in individual patients, such as overall speech fluency, inventory of available utterances, nature of eliciting tasks, and propositionality of responses. Information such as communication disorder diagnosis, underlying etiology, and known sites of lesion from each patient's total clinical profile may also assist with differentiation.

Aphasia↗

Double-blind investigation of two corticoid preparations for the treatment of eczematous skin disorders. Short communication.

In a double blind fully randomised trial, three Belgian dermatologists independently treated 81 patients suffering from various eczematous skin disorders. After four weeks both the dermatologists and their patients assessed the results of a twice-daily topical application of an ointment containing 17 beta-hydroxy-4-estren-3-one-17-decanoate (nandrolone decanoate, Dexatopic) ointment or a reference ointment. Both the dermatologists' and the patients' assessments of the two preparations showed that there was no significant difference between the two treatments although Dexatopic did seem to have a more favourable profile in the "much improved" area. In the total score decrease, there was an indication that Dexatopic had a more favourable effect than the reference preparation.

Clinical Trials as Topic↗