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Medical management of acute bacterial sinusitis. Recommendations of a clinical advisory committee on pediatric and adult sinusitis.

Acute sinusitis is commonly encountered in clinical practice and treated in the primary care setting. The clinician should recognize the subtle clinical presentation of acute bacterial sinusitis and initiate appropriate, aggressive treatment. Other upper respiratory tract disorders can confound the accurate diagnosis and appropriate treatment of sinusitis. Variable patterns of microbial resistance and antibiotic susceptibility and the dissociation between in vitro findings and clinical efficacy are a treatment challenge. This report is a comprehensive review of the pathophysiology and diagnosis of acute sinusitis, infectious agents, treatment methods, antibiotic resistance patterns, and costs associated with the management of sinusitis. Treatment algorithms are presented for adult and pediatric sinusitis.

Acute Disease↗

Scaling properties of the frontal sinus in the African great apes--a clue to the role of the human paranasal sinuses.

The biology of scaling (allometry) can prove a useful tool in comparative anatomical studies. Amongst primates only the African Great Apes and Man possess a frontal sinus. The aim of this study was to identify the allometric properties of the frontal sinus in order to gain clues as to the role of the human paranasal sinuses. A measure of frontal sinus volume was calculated for fifty-seven Great Apes and then scaled against indicators of body size and nasal cavity volume. The results suggest that there are racial variations in frontal sinus size in the African Great Ape populations. This phenomenon mirrors the human condition. The scaling relationships identified in the study lend support to the hypothesis that the frontal sinus has a "structural" rather than a "functional" role.

Animals↗

Endoscopic sinus surgery for the treatment of chronic sinusitis in geriatric patients.

Although endoscopic sinus surgery is a well-documented procedure for the treatment of chronic sinusitis in children and adults, no study has been conducted to specifically investigate its application in a geriatric population. We undertook to fill this void by analyzing the records of 1,112 patients who had undergone endoscopic sinus surgery for chronic sinusitis in our department between April 1988 and March 1998. We categorized these patients by age. There were 171 patients (15.4%) in the geriatric group (age: > or = 65 yr), 837 patients (75.3%) in the adult group (age: 17 to 64), and 104 patients (9.4%) in the pediatric group (age: < or = 16 yr). We found that the geriatric group experienced a disproportionately larger share of operative complications, but most of them were minor. Outcomes were similar in all three groups. We conclude that endoscopic sinus surgery is a safe and effective treatment for older patients with chronic sinusitis.

Adolescent↗

The piezoelectric bony window osteotomy and sinus membrane elevation: introduction of a new technique for simplification of the sinus augmentation procedure.

All of the surgical techniques to elevate the maxillary sinus present the possibility of perforating the schneiderian membrane. This complication can occur during the osteotomy, which is performed with burs, or during the elevation of the membrane using manual elevators. The purpose of this article is to present a new surgical technique that radically simplifies maxillary sinus surgery, thus avoiding perforating the membrane. The piezoelectric bony window osteotomy easily cuts mineralized tissue without damaging the soft tissue, and the piezoelectric sinus membrane elevation separates the schneiderian membrane without causing perforations. The elevation of the membrane from the sinus floor is performed using both piezoelectric elevators and the force of a physiologic solution subjected to piezoelectric cavitation. Twenty-one piezoelectric bony window osteotomy and piezoelectric sinus membrane elevations were performed on 15 patients using the appropriate surgical device (Mectron Piezosurgery System). Only one perforation occurred during the osteotomy at the site of an underwood septa, resulting in a 95% success rate. The average length of the window was 14 mm; its height was 6 mm, and its thickness was 1.4 mm. The average time necessary for the piezoelectric bony window osteotomy was approximately 3 minutes, while the piezoelectric sinus membrane elevation required approximately 5 minutes.

Adult↗

[Treatment of the paranasal sinuses mycosis with endoscopic sinus surgery].

OBJECTIVE: To evaluate the treatment effect of endoscopic sinus surgery on the paranasal sinuses mycosis. METHOD: 29 cases of paranasal sinuses mycosis were treated with endoscopic sinus surgery from 1998. The wound was washed with 1% H2O2 and 0.9% NaCl solution after operation. RESULT: In the follow up of 6-36 months, all cases were cured. CONCLUSION: With the endoscopic sinus surgery, the surgeons can get better illumination and the function of nasal cavity and sinuses can be preserved as many as possible. The success rate was high.

Adult↗

[Treatment of non-invasive aspergillosis of maxillary sinus by functional endoscopic sinus surgery].

OBJECTIVE: To evaluate the treatment of non-invasive aspergillosis of the maxillary sinus by using functional endoscopic sinus surgery (FESS) and the correlated factors that affect the treatment. METHOD: 41 cases of local, non-invasive aspergillosis of the maxillary sinus undergone FESS were studied. RESULT: The period of convalescence of double pathway (via ostium of maxillary sinus and canine fossa) was 4.7 weeks while single pathway (via ostium of maxillary sinus only) was 9.3 weeks. There was significant difference (P < 0.01). The period of convalescence of group using anti-fungal drugs to wash the operative cavity was 6.4 weeks while the group without using drugs was 6.7 weeks. There was no statistic significance (P > 0.05). CONCLUSION: FESS is effective in treating of non-invasive aspergillosis of the maxillary sinus. The operation of double pathway is superior to that of single pathway. Whether to use antifungal drugs to wash the operative cavity has no obvious effect on the efficacy.

Adult↗

Microbiology of sinus puncture versus middle meatal aspiration in acute bacterial maxillary sinusitis.

BACKGROUND: Maxillary sinus puncture is considered the gold standard for diagnosing acute bacterial maxillary sinusitis (ABMS) and for identifying bacterial pathogens in antimicrobial trials of ABMS. However, sinus puncture and aspiration is all invasive, time-consuming procedure that is limited by discomfort to the patient and possible complications. Therefore, the diagnostic usefulness in clinical practice and patient enrollment in studies of ABMS is hindered and alternatives for maxillary sinus puncture are being investigated. METHODS: We designed a prospective clinical and microbiological outpatient study. Cultures obtained by endoscopically guided middle meatal aspiration were compared with those from sinus puncture and aspiration in 24 patients with ABMS. RESULTS: Considering puncture and aspiration as the gold standard, endoscopy cultures provided a sensitivity of 80%, specificity of 100%, positive predictive value of 100%, negative predictive value of 78.6%, and correlation of 88.5%. CONCLUSION: In our study, endoscopic sampling compared favorably with sinus puncture and aspiration.

Adolescent↗

Orbital volumetric analysis of allergic fungal sinusitis patients with proptosis before and after endoscopic sinus surgery.

BACKGROUND: The aim of this study was to examine the changes of orbital volumes in allergic fungal sinusitis (AFS) patients with proptosis who undergo endoscopic sinus surgery. METHODS: A retrospective study of operative patients with proptosis due to AFS was performed. Normative data were obtained using patients with chronic sinusitis without orbital involvement. Orbital volume measurements were obtained using digitized images and computer software to calculate volumes (cm3) of outlined regions on 1.3-mm axial computed tomography images. Orbital volumes were measured as total volumes and volumes within the bony orbit. Bony orbits were defined using two techniques: (1) the region posterior to a line from ipsilateral zygoma to contralateral zygoma and (2) the region posterior to a line from zygoma to ipsilateral lacrimal bone. Four affected orbits in three AFS patients with proptosis were evaluated. Twenty-eight unaffected orbits in 14 patients were used as normal comparisons. RESULTS: Orbital involvement by AFS resulting in proptosis decreased orbital volumes within the bony orbit to a mean of 70% of normal. After successful endoscopic sinus surgery, bony orbital volumes normalize or approach normal ranges to a mean 90% of normal with resolution of clinically apparent proptosis. Total volumes remained stable before and after surgery. CONCLUSION: Massive AFS may affect the orbit resulting in proptosis. Spontaneous orbital remodeling with clinical resolution of proptosis and normalization of bony orbital volumes can be seen in AFS patients several months after sinus surgery and aggressive medical treatment. Surgical orbital reconstruction typically is not needed once the sinus disease is adequately addressed.

Adolescent↗

Radiofrequency sinus excision: better alternative to marsupialization technique in sacrococcygeal pilonidal sinus disease.

BACKGROUND: A number of techniques have been described for treatment of patients with sacrococcygeal pilonidal sinus disease. The author reports his experience in the surgical management of pilonidal sinus using radiofrequency sinus excision technique. The results are compared with those obtained after excision and marsupialization procedure. MATERIALS AND METHODS: Seventeen patients were operated by radiofrequency sinus excision and 18 with excision and marsupialization. An Ellman radiofrequency device was used. The two groups were matched for age, gender and presentation symptoms. The median follow-up was two years. The patient's satisfaction on the outcome of the procedure was also evaluated. RESULTS: In the radiofrequency sinus excision group, we found on average a shorter operation time (10 vs. 36 minutes, p < 0.001), shorter hospitalization (nine vs. 30 hours, p < 0.001), significantly less postoperative pain, fewer cumulatve requests for analgesia by the patients (14 vs. 25 tablets, p < 0.001), and earlier return to work (six vs. 16 days, p < 0.001) The wounds with marsupialization did heal faster than those with sinus excision; however, the difference was not significant. At two year follow-up, one patient from each group had a recurrence. CONCLUSION: This pilot study shows that this new technique can be performed as a day care surgery. With reduced postoperative pain and early resumption to work, patient satisfaction is better in comparison to excision and marsupialization technique.

Adolescent↗

Osteoplastic flap for frontal sinus obliteration in the era of image-guided endoscopic sinus surgery.

BACKGROUND: This study evaluates the management of frontal sinus disease using osteoplastic flap surgery (OPFS) in the current era of image-guided endoscopic sinus surgery (IGESS). STUDY DESIGN: A retrospective chart review was performed of patients who underwent OPFS and imaged-guided endoscopic frontal sintus surgery in the past 10 years at a tertiary care teaching hospital. METHODS: Chart reviews of clinic patients and inpatients who underwent OPFS were performed. Indications for surgery, prior sinus surgeries, time to OPFS, post-OPFS sinus surgeries, and associated comorbid factors were reviewed. RESULTS: In the period under review, 710 IGESS cases were performed. Thirty patients, who were candidates for OPFS, underwent IGESS for frontoethmoid disease. Fourteen patients from this group failed IGESS and underwent OPFS. The indications for OPFS included mucocele in 10 cases, tumors in 2 cases, and trauma in 2 cases. Four patients underwent revision OPFS. The patients who failed IGESS had prior trauma, tumor resection, radiation, or large septate frontal sinus with lateral extension in which the mucocele could not be drained endoscopically. The average time to OPFS was 6.2 years (0-27 years). Nine patients had prior sinus surgery (1-7 prior surgeries) and five patients had subsequent endoscopic surgical procedures. CONCLUSION: In all patients with frontal mucocele, surgery should be attempted endoscopically using IGESS because of the low morbidity of the procedure. Patients with risk factors for failure should be considered for OPFS if IGESS proves to be unsuccessful.

Adult↗

[Effects of digitalis on the parameters of sinus function in sick sinus syndrome. Evaluation using a multiprogrammable permanent atrial pacemaker with temporary inhibition].

A non invasive electrophysiological study was performed in eight patients with sick sinus syndrome using a multiprogrammable AAI pacemaker (Medtronic Spectrax Sxt) with temporary pacing inhibition. We measured the corrected sinus node recovery time and sino-atrial conduction time (Narula method) before and after digoxin administration (acutely iv and orally for 10 days). Digitalis lengthened both the corrected sinus node recovery time and the sino-atrial conduction time; in particular, after the long-term oral treatment sinus function worsened markedly. The prolongation of the sino-atrial conduction time seems to be related to an indirect effect of the drug, since its disappears after atropine administration. Our results suggest that patients with the sick sinus syndrome need permanent pacing when long-term treatment with digitalis is requested; the pacemaker we used permits a non-invasive long-term evaluation of sinus function in such patients.

Administration, Oral↗

[Diagnostic transesophageal atrial stimulation for sinus node function testing. II. Results in patients with and without sinus node syndrome].

By means of transoesophageal atrial stimulation of higher frequency in patients with sinus node syndromes (n = 78) in about 60% of the cases a prolonged sinus node recovery time could be proved. After the end of the stimulation secondary stops appeared in about half of the patients, so that in 81% of the cases at least one pathological result was established. By means of premature individual transoesophageal stimulation (n = 99) in 2/3 of the patients with sinus node syndrome we contrived to perform a calculation of the sinuatrial conduction time. Half of all calculable values were above the normal. In 1/3 of the examined persons pathological stimulation patterns were found. Altogether 90% of the patients showed at least one pathological result, when apart from prolonged sinus node recovery times and sinuatrial conduction times at the same time secondary stops after serial stimulation with higher frequency and abnormal behaviour patterns of the post-extrasystolic stops after individual stimulation were taken into consideration. In patients with different cardiovascular diseases without clinical or electrocardiographic reference to a sinus node dysfunction in 25% of the cases at least one pathological result was found, in which case cannot be clarified, whether latent functional sinus node disturbances or falsely positive results are in question or not. Altogether the non-invasive transoesophageal stimulation technique leads to on principle diagnostic evidences of the same value as the up to now usual stimulation of the right atrium. Methodical problems which arise from the stimulation of the righ atrium in transoesophageal approach are to be taken into consideration in the interpretation of the results.

Adult↗

Intravenous injection of adenosine triphosphate for assessing sinus node dysfunction in patients with sick sinus syndrome.

The clinical value of rapid intravenous injection of adenosine triphosphate (ATP, Adephos Kowa # L3, CAS 56-65-5) for assessing sinus node function was examined in 5 patients with sick sinus syndrome (SSS) and 6 normal controls. All patients with SSS showed cardiac pauses longer than 3 s on a 24-h Holter ECG monitoring. First, after prophylactic insertion of a temporary pacemaker in the right ventricle, overdrive suppression test was conducted using the standard technique, and sinus node recovery time (SNRT) was observed to evaluate the sinus node function. Then, 10 min later, 10 mg of ATP was rapidly injected intravenously, and body surface and intracavitary ECG were continuously recorded until the basal state was regained. The rapid injection of ATP resulted in a slight inhibition of sinus node automaticity in normal subjects, but marked inhibition was in patients with SSS associated with suppression of AV conduction. The longest post ATP atrial cycle (AA interval in the intracavitary ECG showed a close inverse relationship with SNRT corrected for basal sinus length (CSNRT), according to the following formula: longest AA interval (ms) = 3.32 x CSRT (ms) +254.4 (r = 0.91, p < 0.001). The results suggest that rapid intravenous injection is a useful tool for the diagnosis of SSS.

Adenosine Triphosphate↗

The effect of a new ostium and sinus mucosal flaps on mucociliary flow of the maxillary sinus.

To evaluate the effect of a new ostium upon the mucociliary flow of the maxillary sinus, a window in the lateral wall of the sinuses was made and left open in New Zealand rabbits. The contralateral sinuses were used as controls. No change in mucociliary flow was observed, except for a shorter clearance time in sinuses with a new ostium. In the second group of rabbits the maxillary sinus mucosa was elevated at the floor, lateral and medial walls and rotated about 80-90 degrees. The other side acted as control, the mucosa was elevated and put in place again. The mucociliary flow of sinuses with rotation decreased significantly.

Animals↗

[Computer-tomographic scialogy of the inflammatory diseases of nasal sinuses on an aspect of the improvements of classification of sinusitis].

The present-day possibilities of using the computer tomography in the diagnostics of the inflammatory diseases of perirhinal sinuses are discussed. On the basis of an examination of 450 patients with different forms of sinusitis the classification of the inflammatory diseases of perirhinal sinuses is improved, the computer-tomographic scialogy of acute, subacute and chronic productive sinusitis is made clear. The semiotic picture of the uncommon forms of sinusitis such as cholesteatomic, caseosnonecrotic, fungus, atrophic ones are studied. It is demonstrated that the clinical and computer tomographic study allows one to differentiate not only the different forms of sinusitis but also the phases of their progress. The use of computer tomography in evaluating by an expert the suitability of a patient for the professional flying activity is of importance.

Adolescent↗

[Computed tomography of the anterior ethmoid sinuses and its adjacent structures for endoscopic sinus surgery].

Forty adult cadavers were examined by computed tomography (CT) imaging with special attention to the pneumatization of the anterior ethmoid sinus for endoscopic sinus surgery. The study of the specimen was done using coronal section and axial section, sagittal reconstructed images were obtained from the data acquired in the axial plane. The cells of anterior ethmoid sinus were classified into four sub-groups, namely, the pre-infundibular cell (appearance rate 87.5%), the lateral infundibular cell (82.7%), the post-infundibular cell (86.3%) and the bulla cell (100.0%), and the anterior ethmoid sinus was classified into two types, namely, intraethmoid type (71.2%) and extraethmoid type (28.8%). The results shows that CT can display the sub-group and the type of the anterior ethmoid sinus and its adjacent structures clearly. The significance of endoscopic sinus surgery was discussed.

Adult↗

[Study on clinical anatomy of Chinese nasal cavity and paranasal sinus related to functional endoscopic sinus surgery].

The two-dimensional image makes it difficult to determine the anatomic locations during the Functional Endoscopic Sinus Surgery (FESS), which causes many complications. The nasal columella is the best mark to identify the distance to the operating sites during the FESS. In this study, we measured the distances and angles from the base of columella to each important landmark: the anterior end of the middle turbinate, the ethmoid bulla, the posterior and superior end of the uncinate process, the basal lamina, the posterior wall of the ethmoid sinus, the posterior and superior wall of the sphenoid sinus, the anterior and posterior ethmoid artery and the ostia of the frontal sinus and the maxillary sinus in 12 Chinese adult cadavers (24 sides). Then a simple method was proposed to identify where you are operating on and where is the most perilous point. We also paid attention to the thickness of bony wall of the optic nerve canal, the superior wall of the sphenoid sinus, the papyraceous lamina and the septa of the ethmoid air cells and found that the former two were much thicker than the latters. The thicker bony wall may contribute enough safety to the optic nerve and the hypophysis in FESS.

Adult↗

Cavernous sinus thrombophlebitis secondary to sphenoid sinusitis.

Cavernous sinus thrombosis is a serious life threatening condition which usually results from midfacial skin infections. Preantibiotic era mortality rates of 80% have improved markedly because of an early awareness of the condition and prompt initiation of parenteral antibiotics. Sphenoid sinusitis is an uncommon associated cause of cavernous sinus infection and is itself a rare and elusive clinical problem. A case of sphenoid sinusitis and concurrent cavernous sinus thrombophlebitis is presented to highlight the clinical diagnostic considerations with special emphasis on bilateral eye signs as indicators of the impending thrombophlebitic process.

Adolescent↗