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PubMed1992

Contextual and linguistic correlates of intelligibility in children with developmental phonological disorders.

Listeners' glosses of children's intended words provided data for two studies of the potential influence of selected contextual and linguistic variables on word intelligibility. Several regularities associated with the occurrence of unintelligible words were identified. In Study I, intelligibility outcomes were associated with utterance length and fluency, word position, intelligibility of adjacent words, phonological complexity, and grammatical form. In Study II, intelligibility outcomes were associated with phonological complexity, syllabic structure, and grammatical form. Discussion considers the implications of these and other regularities associated with the occurrence of unintelligible words for a comprehensive perspective on the utterance-to-utterance intelligibility deficits of children with phonological disorders of unknown origin.

Child Language↗
PubMed1994

Effects of temporal alterations on speech intelligibility in parkinsonian dysarthria.

The effect of two types of temporal alterations, paced and synthetic, on the intelligibility of parkinsonian dysarthric speech was investigated. Six speakers with idiopathic Parkinson's disease served as subjects. Paced temporal alterations were created by slowing each speaker to 60% of his/her habitual speaking rate. The synthetic alterations were created by modifying the habitual rate speech samples using digital signal processing. Three types of synthetic alterations were examined: Pause Altered, Speech Duration Altered, and Pause and Speech Duration Altered. The 60% of habitual speaking rate condition was more intelligible than the synthetic conditions. In addition, none of the synthetic alterations were found to be more intelligible than samples produced at habitual speaking rates. The results suggest that simple alterations of speech signals do not explain the differences in intelligibility that have been observed when parkinsonian dysarthric speakers reduce speaking rates. Reasons for the failure of synthetic alterations to increase speech intelligibility scores are discussed.

Aged↗
PubMed1995

The influence of speaking rate on vowel space and speech intelligibility for individuals with amyotrophic lateral sclerosis.

The relationship between speaking rate, vowel space area, and speech intelligibility was studied in a group of 9 subjects with amyotrophic lateral sclerosis (ALS) and 9 age- and gender-matched controls. Subjects read a standard passage (the Farm Passage) at three speaking rates, including HABITUAL, FAST, and SLOW. Vowel segment durations and target formant frequencies were measured at each speaking rate from select words containing the vowels /i/, /ae/, /a/, and /u/. To quantify changes in vowel space area across speaking rate, the area of the vowel quadrilateral was calculated for each speaker at each speaking rate. In addition, intelligibility estimates at each speaking rate were obtained for the dysarthric speakers. Results revealed that dysarthric speakers exhibited smaller vowel space areas and less systematic changes in vowel space as a function of speaking rate, when compared to the neurologically intact speakers. In an examination of the relationship between vowel space area and speech intelligibility, vowel space was found to account for 45% of the variance in speech intelligibility. This result suggests that vowel space area is an important component of global estimates of speech intelligibility.

Adult↗
PubMed2000

Perceptual-phonetic predictors of single-word intelligibility: a study of Cantonese dysarthria.

This study investigated the perceptual-phonetic predictors of intelligibility in Cantonese speakers with dysarthria. The speakers were 20 young adults with cerebral palsy. The listener group consisted of 12 native Cantonese speakers. A single-word intelligibility test was constructed, based on 17 phonetic contrasts. There were no significant differences in intelligibility for gender, age, or type of cerebral palsy. A regression analysis showed that intelligibility could be predicted with 97% accuracy by 5 out of the 6 most problematic contrasts. Three contrasts (glottal vs. null, final vs. null, and long vs. short vowel) predicted variation on an independent intelligibility measure obtained for the same speakers with 84% accuracy. Principal components analysis derived 4 components, which accounted for 81% of the variance in the 17 contrasts. Physiological explanations and language-specific contributions to speech disorder in this group of speakers are discussed.

Adolescent↗
PubMed1995

From intelligence to evidence-based healthcare: a purchasing odyssey.

Since the appearance of the NHS Executive's guidance document, Purchasing Intelligence (1991), efforts have been concentrated on the development of 'purchasing intelligence facilities' staffed, in the main, by health librarians. However, the concept of 'intelligence' has a wider dimension that impacts upon the whole culture of an organization. The authors examine purchasing organizations against popular theories of organizational development. The characteristics of Handy's Task culture, with Athena as its patron, may be observed in many authorities. Using the results of two surveys, conducted in March 1995, they identify some key information management issues involving structure, tasks, technology and people. Skills in information 'transformation' must be acquired by all staff in purchasing authorities. The intelligence officer must become a modern-day Odysseus if the intelligence facility is to 'survive and thrive'.

Computer Communication Networks↗
PubMed1999

Information and redundancy: key concepts in understanding the genetic control of health and intelligence.

A model is proposed in which information from the environment is analysed by complex biological decision-making systems which are highly redundant. A correct response is intelligent behaviour which preserves health; incorrect responses lead to disease. Mutations in genes which code for the redundant systems will accumulate in the genome and impair decision-making. The number of mutant genes will depend upon a balance between the new mutation rate per generation and systems of elimination based on synergistic interaction in redundant systems. This leads to a polygenic pattern of inheritance for intelligence and the common diseases. The model also gives a simple explanation for some of the hitherto puzzling aspects of work on the genetic basis of intelligence including the recorded rise in IQ this century. There is a prediction that health, intelligence and socio-economic position will be correlated generating a health differential in the social hierarchy. Furthermore, highly competitive societies will place those least able to cope in the harshest environment and this will impair health overall. The model points to a need for population monitoring of somatic mutation in order to preserve the health and intelligence of future generations.

Genetic Predisposition to Disease↗
PubMed1991

[Speech intelligibility and psychosocial adaptation in various voice rehabilitation methods following laryngectomy].

Intelligibility and psychosocial adjustment are measured by the PLTT (Post-Laryngectomy-Telephone-Test) and a newly developed questionnaire (FPAL). 110 male patients with total or partial laryngectomies are tested. Three different groups are compared with each other: laryngectomees with voice prostheses, laryngectomees with oesophageal voice or artificial larynx, and patients with partial laryngectomies. As was to be expected, intelligibility (single words and sentences) was best in patients with partial laryngectomies. The intelligibility of the laryngectomees with voice prostheses is significantly higher than the intelligibility of patients with oesophageal voice or artificial larynx. There was no difference between the groups with regard to the subjective assessment of intelligibility in relation to various communication partners. Partial laryngectomies have the lowest negative impact on the social and psychological situation of the patients. Laryngectomees, however, are more lonely, indicate more psychological stress in social interactions, and have a less positive evaluation of their life. Statistical analyses reveal no difference in psychosocial adjustment between laryngectomees with voice prostheses, oesophageal voice and artificial larynges.

Adaptation, Psychological↗
PubMed2004

Methodological aspects of assessing speech intelligibility among children with impaired hearing.

OBJECTIVE: In the assessment of speech intelligibility, procedures that are easy to use, but also valid and reliable, are needed. The aim of this study was to explore the reliability and concurrent validity of two scaling methods for assessing the speech intelligibility of children with impaired hearing. MATERIAL AND METHODS: A total of 51 children aged 4-17 years with a mild to profound hearing impairment performed a naming task comprising 62 single words. Altogether, 85 inexperienced listeners, divided into 17 panels, assessed the speech production of the children. A percent correct score (for identification of the words) was obtained from every listener. The listeners were also asked to judge the overall intelligibility of each child using a visual analogue scale (VAS) and a four-point ordinal level rating scale with verbal descriptors. RESULTS: The percent correct score correlated significantly both with the VAS and the rating scale with verbal descriptors (Pearsons' coefficient 0.90 and Spearman's coefficient 0.78, respectively). Also, the VAS and the scale with verbal descriptors were significantly intercorrelated (Spearman's rho 0.85). Moderate to high correlations were usually obtained for all grades of hearing impairment, both sexes, different age groups and main communication modes. CONCLUSIONS: Especially for assessing the need for remediation of speech and in monitoring its effectiveness, a quick overall estimate of speech intelligibility can be obtained quite reliably using the above rating scales. Item identification is more time-consuming but is often needed in research and therapy planning, where acoustic and linguistic phenomena that reduce intelligibility need to be traced.

Adolescent↗
PubMed1998

Auditory vs visual speech timing cues as external rate control to enhance verbal intelligibility in mixed spastic-ataxic dysarthric speakers: a pilot study.

Metronome, singing, and board pacing were used as external rate control techniques for the purpose of comparing the effectiveness of auditory and visual speech timing cues for reducing speech rate and increasing intelligibility in three traumatically brain injured mixed spastic-ataxic dysarthric speakers. A single system design with baseline reversal (ABACAD) was used in this preliminary investigation. Results demonstrated statistically significant (p < 0.05) changes in increased speech intelligibility during all three pacing conditions for the two more involved subjects. Differences between treatment conditions were not statistically significant. However, auditory metronome cuing showed the best results for the two subjects who benefited from rate control. Lower baseline intelligibility was strongly correlated with higher benefit from rate control. Furthermore, the two auditory rhythmic pacing conditions exhibited a close synthronization effect between the frequency rate of the cue and speech rate. Significant correlation coefficients between decreased speech rate and increased intelligibility were only found for the two more involved subjects. These findings suggested a differential benefit of slowing speech rate to improve intelligibility contingent upon severity of speech deficits.

Adult↗
PubMedDate not supplied

Speech rate effects upon intelligibility and acceptability of dysarthric speech.

Sentences recorded by four speakers with dysarthria and two control speakers were presented to listeners at three different rates: habitual, a 30% slower rate and a 30% higher rate. Rate changes were made by digitally manipulating the habitual sentences. Thirty young normal adult listeners rated the sentences for intelligibility (per cent correct words) and acceptability (via 9-point equal interval scale ranging from "terrible" through "excellent"). Intelligibility for each speaker remained unchanged across rate changes. Acceptability improved as rates increased for the two more intelligible impaired speakers. For the less intelligible impaired speakers, ratings were better and similar for the habitual and fast speaking rate conditions. Results are discussed in terms of the objective nature of intelligibility ratings vs. the subjective ratings of acceptability.

Aged↗
PubMedDate not supplied

Relationship between circulating levels of sex hormones and insulin-like growth factor-1 and fluid intelligence in older men.

The relationship was investigated between baseline serum levels of total testosterone (T), free testosterone (FT), dehydroepiandrosterone sulfate (DHEAS), ESTRADIOL (E2), sex hormone-binding globulin (SHBG), insulin-like growth factor-1 (IGF-1) and cognitive functioning in 25 healthy older men (mean age 69.1 years). Cognitive tests concerned measures not sensitive to ageing (crystallized intelligence), and measures sensitive to ageing (fluid intelligence and verbal long-term memory). Partial correlation coefficients (controlled for level of education) revealed significant associations of total T (r = -.52, p = -.009), SHBG (r - .59, p = .002) and IGF-1 (r = .54, p = .007) with the composite measure of fluid intelligence test performance, but not with crystallized intelligence, nor verbal long-term memory. Stepwise hierarchical regression analysis with the composite measure of fluid intelligence as the dependent variable showed that the contributions of SHBG, total T, and IGF-1 were not additive.

Aged↗
PubMed2001

Artificial intelligence applications in the intensive care unit.

OBJECTIVE: To review the history and current applications of artificial intelligence in the intensive care unit. DATA SOURCES: The MEDLINE database, bibliographies of selected articles, and current texts on the subject. STUDY SELECTION: The studies that were selected for review used artificial intelligence tools for a variety of intensive care applications, including direct patient care and retrospective database analysis. DATA EXTRACTION: All literature relevant to the topic was reviewed. DATA SYNTHESIS: Although some of the earliest artificial intelligence (AI) applications were medically oriented, AI has not been widely accepted in medicine. Despite this, patient demographic, clinical, and billing data are increasingly available in an electronic format and therefore susceptible to analysis by intelligent software. Individual AI tools are specifically suited to different tasks, such as waveform analysis or device control. CONCLUSIONS: The intensive care environment is particularly suited to the implementation of AI tools because of the wealth of available data and the inherent opportunities for increased efficiency in inpatient care. A variety of new AI tools have become available in recent years that can function as intelligent assistants to clinicians, constantly monitoring electronic data streams for important trends, or adjusting the settings of bedside devices. The integration of these tools into the intensive care unit can be expected to reduce costs and improve patient outcomes.

Algorithms↗
PubMed1988

Changes in aesthetic appearance and intelligibility of speech after partial glossectomy in patients with Down syndrome.

Eight patients with Down syndrome, aged 9 years and 10 months to 25 years and 4 months, underwent partial glossectomy. Preoperative and postoperative videotaped samples of spoken words and connected speech were randomized and rated by two groups of listeners, only one of which knew of the surgery. Aesthetic appearance of speech or visual acceptability of the patient while speaking was judged from visual information only. Judgments of speech intelligibility were made from the auditory portion of the videotapes. Acceptability and intelligibility also were judged together during audiovisual presentation. Statistical analysis revealed that speech was significantly more acceptable aesthetically after surgery. No significant difference was found in speech intelligibility preoperatively and postoperatively. Ratings did not differ significantly depending on whether the rater knew of the surgery. Analysis of results obtained in various presentation modes revealed that the aesthetics of speech did not significantly affect judgment of intelligibility. Conversely, speech acceptability was greater in the presence of higher levels of intelligibility.

Adolescent↗
PubMed2006

Callsign Acquisition Test (CAT): speech intelligibility in noise.

OBJECTIVE: The study was designed to assess the effects of noise on the intelligibility of speech elements used in the Callsign Acquisition Test (CAT), developed by the U.S. Army Research Laboratory. The CAT consists of 126 test items, or callsigns, each of which is made up of a two-syllable word selected from the 18-item military alphabet (Alpha-Zulu) followed by a one-syllable number (all numbers from 1 to 8, excluding 7). DESIGN: The CAT items were mixed with one of three different types of background noises (pink noise, white noise, and multitalker babble) and presented to 18 listeners. Speech-to-noise ratio for all three noises and the overall level of pink noise were varied in two separate experiments to determine how these variables affected speech intelligibility of the CAT items pronounced by a male talker. CONCLUSIONS: Test results demonstrate speech-to-noise ratio has a significant effect on speech intelligibility of the CAT items under all conditions. Pink noise generated the lowest speech intelligibility scores followed by multitalker babble and then white noise. A change in the overall level of pink noise had only small effect on CAT intelligibility.

Acoustic Stimulation↗
PubMed2004

Use of artificial intelligence to identify cardiovascular compromise in a model of hemorrhagic shock.

OBJECTIVE: To determine whether a prototype artificial intelligence system can identify volume of hemorrhage in a porcine model of controlled hemorrhagic shock. DESIGN: Prospective in vivo animal model of hemorrhagic shock. SETTING: Research foundation animal surgical suite; computer laboratories of collaborating industry partner. SUBJECTS: Nineteen, juvenile, 25- to 35-kg, male and female swine. INTERVENTIONS: Anesthetized animals were instrumented for arterial and systemic venous pressure monitoring and blood sampling, and a splenectomy was performed. Following a 1-hr stabilization period, animals were hemorrhaged in aliquots to 10, 20, 30, 35, 40, 45, and 50% of total blood volume with a 10-min recovery between each aliquot. Data were downloaded directly from a commercial monitoring system into a proprietary PC-based software package for analysis. MEASUREMENTS AND MAIN RESULTS: Arterial and venous blood gas values, glucose, and cardiac output were collected at specified intervals. Electrocardiogram, electroencephalogram, mixed venous oxygen saturation, temperature (core and blood), mean arterial pressure, pulmonary artery pressure, central venous pressure, pulse oximetry, and end-tidal CO(2) were continuously monitored and downloaded. Seventeen of 19 animals (89%) died as a direct result of hemorrhage. Stored data streams were analyzed by the prototype artificial intelligence system. For this project, the artificial intelligence system identified and compared three electrocardiographic features (R-R interval, QRS amplitude, and R-S interval) from each of nine unknown samples of the QRS complex. We found that the artificial intelligence system, trained on only three electrocardiographic features, identified hemorrhage volume with an average accuracy of 91% (95% confidence interval, 84-96%). CONCLUSIONS: These experiments demonstrate that an artificial intelligence system, based solely on the analysis of QRS amplitude, R-R interval, and R-S interval of an electrocardiogram, is able to accurately identify hemorrhage volume in a porcine model of lethal hemorrhagic shock. We suggest that this technology may represent a noninvasive means of assessing the physiologic state during and immediately following hemorrhage. Point of care application of this technology may improve outcomes with earlier diagnosis and better titration of therapy of shock.

Animals↗
PubMed2003

Accurate intelligence assessments in social interactions: mediators and gender effects.

Research indicates that people can assess a stranger's measured intelligence more accurately than expected by chance, based on minimal information involving appearance and behavior. The present research documents behavioral correlates of perceived and measured intelligence and identifies behaviors that mediate the relationship between perceived and measured intelligence. In particular, when judges rated targets with video and auditory stimuli available, responsiveness to conversation partner, eye-gaze, and looking at partner while speaking were each significant mediators in the accurate assessment of intelligence. Each of those behaviors, as well as the percentage of looking at partner while speaking as a function of the target's own speaking time, were significant mediators in the video silent condition. Additionally, judge and target gender contributed to accurate intelligence assessments.

Adolescent↗
PubMed2005

Show me the child at seven II: Childhood intelligence and later outcomes in adolescence and young adulthood.

BACKGROUND: There has been ongoing interest in the role of intelligence in longer-term educational and occupational achievement and social adjustment. The aims of this study were to examine the extent to which IQ in middle childhood (8-9 years) was prognostic of future outcomes when due allowance was made for confounding personal and social factors. METHODS: Data were gathered on (WISC-R) IQ at ages 8-9 years and a range of educational and social adjustment measures over the course of the Christchurch Health and Development Study, a 25-year longitudinal study of a birth cohort of 1,265 New Zealand children. RESULTS: IQ assessed at ages 8-9 years was related to a range of outcomes: later crime (offending, arrest/conviction); substance use disorders (nicotine dependence, illicit drug dependence); mental health (anxiety, suicidality); sexual adjustment (number of sexual partners, pregnancy); educational achievement (school leaving qualifications, tertiary qualifications); and occupational outcomes (unemployment, income). However, intelligence was largely unrelated to many of these outcomes: crime, mental health, sexual behaviours, and illicit substance dependence after statistical adjustment for early behaviour problems and family background. Strong relationships remained between childhood intelligence and later educational and occupational outcomes. CONCLUSIONS: Much of the association between early intelligence and later social adjustment is mediated by childhood conduct problems and family social circumstances. However, strong relationships exist between early intelligence and later academic achievement and income independently of these factors.

Achievement↗
PubMed2003

Segmental intelligibility of four currently used text-to-speech synthesis methods.

The study investigated the segmental intelligibility of four currently available text-to-speech (TTS) products under 0-dB and 5-dB signal-to-noise ratios. The products were IBM ViaVoice version 5.1, which uses formant coding, Festival version 1.4.2, a diphone-based LPC TTS product, AT&T Next-Gen, a half-phone-based TTS product that uses harmonic-plus-noise method for synthesis, and FlexVoice2, a hybrid TTS product that combines concatenative and formant coding techniques. Overall, concatenative techniques were more intelligible than formant or hybrid techniques, with formant coding slightly better at modeling vowels and concatenative techniques marginally better at synthesizing consonants. No TTS product was better at resisting noise interference than others, although all were more intelligible at 5 dB than at 0-dB SNR. The better TTS products in this study were, on the average, 22% less intelligible and had about 3 times more phoneme errors than human voice under comparable listening conditions. The hybrid TTS technology of FlexVoice had the lowest intelligibility and highest error rates. There were discernible patterns of errors for stops, fricatives, and nasals. Unrestricted TTS output--e-mail messages, news reports, and so on--under high noise conditions prevalent in automobiles, airports, etc. will likely challenge the listeners.

Adolescent↗