Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Tooth Calcification”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 379 records · Page 21Linked to original sources

Fluoride therapy in clinical practice.

Research into the use of fluorides is dynamic and ongoing. As a consequence, anyone interested in clinical application must be up to date in the current literature. A number of other trace elements have also been found to have impact, particularly on the disease of dental caries. Therefore, to treat oral disease effectively with these products, it is important that the clinician keep current with published studies. Fluorides are, at present, a major therapeutic measure in the treatment of both dental caries and periodontal disease. However, fluorides will only reduce disease, not eliminate it. Other therapy, including improved diet and hygiene, is necessary to bring this about. Therefore, fluorides should be considered as an adjunct to treatment and not total treatment. No one can stop caries attack or eliminate established periodontal pockets with fluoride alone.

Adolescent↗

Effect of 1-p-bromotetramisole on mineralization of hamster tooth germs in vitro: a light and electron microscopic study.

In culture, 10(-3)M 1-p-bromotetramisole (1-pBTM) inhibited mineralization of in vitro secreted enamel matrix in two-day old neonatal hamster first maxillary molar tooth germs. In contrast, in control tooth germs cultured without the inhibitor, new enamel and dentin matrices were secreted and subsequently mineralized in vitro. It is suggested that the arrested enamel matrix mineralization in vitro is a result of reduced phosphate uptake due to alkaline phosphatase inhibition by 1-pBTM. In addition, 1-pBTM induced accumulation of secretory granules in odontoblasts and ameloblasts, but not in the other cells. This is probably a specific effect of the inhibitor on these cells due to alkaline phosphatase inhibition.

Alkaline Phosphatase↗

A histological study of the innervation of developing mouse teeth.

The innervation of developing mouse teeth between initial formation and crown formation was investigated using silver-stained serial sections. The developing innervation correlated with the stage of development of individual teeth rather than the chronological age of the mice. Nerves approached the developing dental papilla during the bud stage and formed a basal plexus below the dental papilla in the early cap stage. Nerve fibres from this plexus spread into the dental follicle as it began to develop. However, nerves did not enter the dental papilla until crown formation commenced, when the innervation was fairly rapid. Innervation commenced in the incisor teeth as soon as dentinogenesis started but not until a thin layer of enamel had been formed in the molar teeth. Although some of the early fibres were associated with blood vessels, many nerves lay free in the pulp. The absence of nerves in intimate relationship to the presumptive dental regions during the inductive phase of tooth development suggests that neural induction plays no part in the initiation of odontogenesis. However, it is not possible, from a purely histological study such as this, to attribute any function to the nerves at other stages of tooth development until the neurotransmitter content, and hence the type and likely function of the nerves, is established.

Amelogenesis↗

Progressive mineralization pattern of developing enamel during the maturation stage.

The maturation stage of developing enamel may be divided into three substages: First, a secondary mineralization increase appears from the surface toward the deeper layer; then, a tertiary mineralization increase takes place from the deeper layer toward the surface; and finally, the narrow subsurface layer mineralizes heavily and attains the highest degree of mineralization of all layers.

Animals↗