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Results for “Muscle Neoplasms”

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At least 379 records · Page 21Linked to original sources
PubMed1992

Different origin of leiomyoblastoma by immunohistochemical study.

Leiomyoblastoma has been regarded as a neoplasm of smooth muscle origin. With recent progress in immunohistostaining techniques, many clinicopathological discrepancies have been pointed out about the origin of leiomyoblastoma. It has been claimed that gastrointestinal non-epithelial tumors should be regarded as stromal tumors in order to study their origin. In the present study, we performed various forms of immunohistostaining in seven cases of leiomyoblastoma to determine their origin. One case expressed desmine and muscle specific actin and was considered to be derived from smooth muscle. Four neoplasms expressed X-100 protein (two cases were also NSE positive) and were thought to be derived from the nerve. Two cases were of unknown derivation. These results suggest that the cells of leiomyoblastoma may arise from a primitive to totipotential cell of neural lineages that may anomalously express smooth muscle filaments.

Actins↗
PubMed1981

Fine structure of granular cell tumor of Abrikosov.

The case report illustrates the microscopical and ultrastructural findings obtained in a case of Abrikossoff's tumor. On the basis of the light and ultrastructural data a neural histogenesis is suggested.

Adult↗
PubMed1997

Orbital granular cell tumor developing in the inferior oblique muscle.

PURPOSE: To describe the magnetic resonance imaging and histopathologic features of an orbital granular cell tumor. METHODS: A 43-year-old man was initially examined with slowly progressive vertical diplopia. A firm mass was palpable through the left lower eyelid. Magnetic resonance imaging and histopathologic examinations were performed. RESULTS: Magnetic resonance imaging disclosed a spindle-shaped mass involving the inferior oblique muscle. Histopathologic examination disclosed that the tumor cells, diagnosed as a granular cell tumor, had infiltrated the muscle fibers. CONCLUSION: In the present case, these findings indicate that the granular cell tumor may develop in the inferior oblique muscle.

Adult↗
PubMed2003

Intramuscular hemangiomas of extraocular muscles.

PURPOSE: To report two patients, 3 and 40 years of age, respectively, each of whom had an isolated intramuscular hemangioma of an extraocular muscle. DESIGN: Two retrospective, interventional case reports. INTERVENTION: Incisional biopsy and short-term oral corticosteroids. MAIN OUTCOME MEASURES: Clinical observation and pathologic examination of specimens and tumor status, visual acuity, and ocular motility at final follow-up. RESULTS: Orbital magnetic resonance imaging revealed that, compared with other extraocular muscles, the tumor was isointense on T1-weighted scans and hyperintense on T2-weighted images. Marked homogeneous enhancement was observed after contrast agent administration. Biopsy results showed a hemangioma of the lateral rectus muscle with predominantly capillary-like small vessels in the child and a mixed small and large vessel type hemangioma of the medial rectus muscle in the adult. CONCLUSIONS: Intramuscular hemangiomas may cause painless, isolated extraocular muscle enlargement in children and in adults without disturbing the ocular motility. The tumors do not seem to be sensitive to systemic corticosteroid therapy.

Administration, Oral↗
PubMed1996

Echographic evaluation and findings in metastatic melanoma to extraocular muscles.

PURPOSE: Metastatic melanoma to the extraocular muscles is an extremely rare condition characterized by marked enlargement of the involved muscles. The authors describe the echographic characteristics of metastatic melanoma to extraocular muscles. METHODS: The authors used standardized echography (standardized A-scan and contact B-scan) to examine two patients known to have malignant melanoma elsewhere with metastatic melanoma to the extraocular muscles. Both patients had orbital lesions with similar echographic characteristics. RESULTS: Echographically, metastatic melanoma to an extraocular muscle spares the tendon and produces marked thickening of the muscle belly fibers. Other echographic findings include low internal reflectivity, regular internal structure, and vascularity (similar to uveal melanoma). These previously unreported echographic features may be unique to metastatic melanoma to an extraocular muscle. CONCLUSION: Echography can be a useful adjunct in detecting and diagnosing suspected metastatic melanoma to the extraocular muscles in patients with clinical signs of an orbital mass and known melanoma elsewhere or in the absence of a known primary lesion.

Adult↗
PubMed1996

Oral infiltrating lipomas.

Infiltrating lipomas are unusual benign tumours of mesodermal origin which infiltrate adjacent skeletal muscle and tend to recur after excision. We report three previously unrecorded cases that developed about the mouth, and describe the clinical characteristics of these lesions, together with those of the seven previously reported cases. We have identified a number of differences from oral lipomas that could be of diagnostic value.

Adolescent↗
PubMed2003

Primary perineal alveolar rhabdomyosarcoma metastatic to an extraocular muscle.

A 17-year-old boy diagnosed with an alveolar rhabdomyosarcoma involving the perineum and with extensive lymphadenopathy was treated with chemotherapy yet developed metastases to the head and neck 6 months into therapy. Ten months after initial diagnosis, while receiving salvage chemotherapy and radiotherapy, he returned with pain on movement of his left eye, proptosis, and ptosis of the left upper eyelid. Computed tomography (CT) revealed a mass within the left lateral rectus muscle that biopsy confirmed to be metastatic alveolar rhabdomyosarcoma. Despite continued chemotherapy and radiotherapy, he ultimately died of the disease. Alveolar rhabdomyosarcoma from distant sites rarely metastasizes to the extraocular muscles. However, our case shows that alveolar rhabdomyosarcoma may metastasize to the orbit and involve a single muscle.

Adolescent↗
PubMed2004

Orbital lymphoid tumour located within an extraocular muscle.

A rare case of an orbital lymphoid tumour within an extraocular muscle is presented. The tumour displayed features of a progressive indolent systemic lymphoma. There was no response to a trial of chemotherapy and so local radiotherapy was instituted. At follow up 2 months later there was no evidence of disease.

Adult↗