Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “MASTURBATION”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 379 records · Page 21Linked to original sources

A pilot study of a structured interview addressing sexual function in men with schizophrenia.

Twenty physically healthy men with schizophrenia responded to a 15-item questionnaire inquiring about their usual and their present (on medications) sexual functioning. Two summary measures of present impairment (the average of items 7-13 that detail the patients' specific complaints of impairment, and item 15, the interviewer's global judgment of impairment) were significantly correlated with each other and with the differences between usual and present reported frequencies of erection and masturbation. More severe impairment on these summary measures was significantly associated with greater biological evidence of dopamine blockade (more severe extrapyramidal side effects and higher serum prolactin levels).

Adult↗

Sexual behavior frequency and biphasic ovulatory type menstrual cycles.

College students whose menarche had occurred 7 years previously, prospectively recorded menstrual and sexual behavior history for 14 weeks as well as basal body temperatures. Regular weekly coital activity associates with the highest incidence of fertile type cycles in this sample of young women as follows: (1) Regular weekly heterosexual behavior was associated with 29.5 +/- 3 day menstrual cycle length. Less frequent sexual activity (sporadic) and celibacy were associated with an increased frequency of aberrantly short and long cycle lengths. (2) Either of two heterosexual behaviors (coitus and/or genital stimulation by a man) were behaviors which were adequate as associates of 29.5 +/- 3 day cycles. (3) Self-stimulation (masturbation to orgasm) was inadequate as an associate of the above-described pattern of menstrual cyclicity. (4) Women with regular weekly coital activity had the highest incidence (90%) of fertile type basal body temperature (BBT) rhythms. Sporadically active women had the next highest incidence (55%) of fertile type BBT rhythms. Celibate women had the lowest incidence (44%) of fertile type BBT's.

Adolescent↗

Influence of prostaglandin F2 alpha on sperm production and seminal characteristics of the stallion.

Six mature stallions were used to test the effect of prostaglandin F2 alpha (PGF2 alpha ) on sperm production and seminal characteristics. Semen was collected from each stallion twice weekly 1 hr following a 10 mg intramuscular injection of PGF2 alpha or a sham injection. A switchback design was used so that three stallions received PGF2 alpha and three served as controls during the first 9 weeks (period 1). Treatment regimens were reversed during the second 9 weeks (period 2). Treatment of stallions with PGF2 alpha resulted in an increase (P less than .05) in gel free seminal volume and a decrease in sperm cell concentration. Total spermatozoa, sperm cell motility, and percentage of primary and secondary sperm abnormalities of ejaculates were not significantly affected by treatment of stallions with PGF2 alpha before semen collection. All treated stallions exhibited a pronounced sweating response to the drug. During the experiment, two of the six stallions masturbated within 20 to 30 minutes after PGF2 alpha treatment without achieving an erection.

Animals↗

Quinelorane (LY163502), a D2 dopamine receptor agonist, acts centrally to facilitate penile erections of male rhesus monkeys.

The present study examined the effects of a specific D2 dopamine receptor agonist, quinelorane (LY163502), on male sexual responding of rhesus monkeys. The effects of quinelorane were assessed by observing the behavioral responses of male rhesus monkeys to a sexually receptive female monkey that they could see, hear, and smell, but not physically contact. Quinelorane (IM) treatment produced dose-dependent effects on male sexual responding. Penile erections and masturbation were markedly facilitated following treatment with either 2.5 or 5 micrograms/kg quinelorane. Higher doses of quinelorane (10 and 25 micrograms/kg) generally did not further augment sexual responding, but rather resulted in a return in sexual responding to control vehicle levels. Quinelorane had a biphasic effect on yawning behavior of the monkeys with low doses (2.5 and 5 micrograms/kg) facilitating yawning and high doses (25 micrograms/kg) inhibiting yawning. Quinelorane in the dose-range (1-25 micrograms/kg) being evaluated did not reliably influence stereotypic behavior. In order to determine whether quinelorane acts centrally or peripherally to stimulate male sexual behavior, the ability of the peripherally active dopamine antagonist, domperidone, and the centrally active dopamine antagonist, haloperidol, to block the facilitation of sexual behavior produced by quinelorane treatment was examined. Administration of domperidone (50-200 micrograms/kg) failed to block quinelorane's effects on sexual behavior, whereas treatment with haloperidol (5-20 micrograms/kg) prevented quinelorane from stimulating male sexual responding. These experiments provide further evidence that dopaminergic mechanisms may play a role in the regulation of male sexual behavior of rhesus monkeys and, in particular, demonstrate the sexual stimulant properties of agents that provide central stimulation to D2 dopamine receptor sites.

Animals↗

Increased sexual behavior in male Macaca arctoides monkeys produced by atipamezole, a selective alpha 2-adrenoceptor antagonist.

The effect of a highly selective and potent alpha 2-adrenoceptor antagonist, atipamezole, on sexual behavior was studied in three stumptail macaques (Macaca arctoides). Following IM administration of atipamezole or saline control, the behavior of the male monkey with a female monkey was observed for 30 min. Atipamezole dose dependently (0.01-0.15 or 0.30 mg/kg) produced a significant increase in the number of ejaculations in all three monkeys, including an old one with decreased sexual activity in control conditions. Both ejaculations obtained by copulation and masturbation were increased. It is concluded that atipamezole is effective in increasing sexual behavior in male stumptail monkeys.

Adrenergic alpha-Antagonists↗

Male chacma baboon (Papio ursinus) sexual arousal: mediation by visual cues from female conspecifics.

(1) The changes in masturbatory behavior for nine adult males exposed to, but not allowed to contact, naturally cycling stimulus females were quite similar to the changes in perineal swelling shown by these females. (2) Serum testosterone concentrations of seven adult males exposed to a cycling stimulus female were related to their masturbatory behavior, with high levels occurring during the females follicular phase, (3) Graded estradiol benzoate treatments of ovariectomized stimulus females revealed individual dosage levels below which there was no positive effect on the occurrence of visually stimulated male masturbation, (4) The present series of experiments documents the importance which visual cues have in the sexual interactions of this particular species.

Animals↗

The genealogical descent of sexual psychoneuroendocrinology from sex and health theory: the eighteenth to the twentieth centuries.

In the aftermath of the inquisition, secular health theory became separate from sacred health theory. Both assimilated vital spirits or sympathies as explanatory concepts. Sympathies were progressively transformed into internal secretions and the hormones of endocrinology. The sexual genealogy of psychoneuroendocrinology traces back to the sexual transplantation experiments of John Hunger (1728 - 93). Sexology, the science, has the same genealogy, whereas sexosophy, the philosophy, does not. In sexosophy, the theory that vital spirits or sympathies lost by masturbation caused debility or degeneracy became, along with health-food and exercise theories, popular in 19th-century health doctrine. Graham crackers and kellogg's cornflakes were by-products of the diet/abstinence doctrine. With police power under the Comstock Law (1873), 19th-century sexosophy negated sexuality so effectively that human sexual psychoneuroendocrine research remains muffled and deprived of funds in 1983.

Alcohol Drinking↗

De virginibus puerisque: the function of the human foreskin considered from an evolutionary perspective.

The functional significance of the human male foreskin is considered in evolutionary terms. It is postulated that there is a lifetime's reproductive advantage in delaying the age of first coitus, and hence of first childbirth, for some years after puberty, until the parents are better established as providers. Phimosis and preputial adhesions are common in human males because they have selective advantage, tending to impede and therefore delay the onset of sexual activity. The physical signs of female virginity have an analogous function, and have been selected for in the same way. This hypothesis also provides a consistent explanation for the worldwide tradition of circumcision and for the common practice of masturbation by human males.

Adolescent↗

Semen finger print.

A correlation between testosterone (T) and dihydrotestosterone (DHT) exists in seminal plasma. These androgens play a role in sperm maturation. The T/DHT ratio is different from one person to the other, due to the heterogenicity of seminal plasma which stems for the most part from the male accessory sex glands, the prostate and seminal vesicles, and also from the 'epididymo-testicular unit'. This ratio is useful in identifying the person's semen. Consequently, the steroid values from assailant semen or accused persons and semen on the victim's clothes are of cardinal importance in matching. The results reported include data on the validation of this technique as a tool for semen identification. Coital and masturbated semen were correlated, and consecutive coital semen were also analysed. It may be concluded that the T/DHT value is specific for each person.

Coitus↗

Posttraumatic erectile potential of spinal cord injured men: how physiologic recordings supplement subjective reports.

OBJECTIVE: To investigate by means of a neurophysiologic model the remaining erectile function in spinal cord injured men. DESIGN: A nonrandomized control trial. SETTING: A Referred Care Center. SUBJECTS: Forty-seven spinal cord injured men and 7 noninjured controls. INTERVENTION: The subject penile responses were recorded by a penile strain gauge during two sessions--one to obtain baseline responses, and one with reflexogenic stimulation (masturbation) and psychogenic stimulation (film). MEASURES: Average tumescence, maximal tumescence, percentage rigidity, and duration of tumescence and rigidity. RESULTS: Significant results were found for subjects with lower lesions using psychogenic stimulation as their optimal mode compared with reflexogenic stimulation as an alternate mode, and for subjects with higher lesions using reflexogenic stimulation as their optimal mode, compared with psychogenic stimulation as an alternate mode. The responses with optimal stimulation modes were comparable to those achieved by controls. CONCLUSION: The findings validate the neurophysiologic model of posttraumatic erectile potential as a function of the lesion type and stimulation source. The results were comparable to those of noninjured subjects; the potential for normal function is present and may be amenable to sexual rehabilitation or use in conjunction with new oral drug treatments for impotence.

Adolescent↗

Seminal reactive oxygen species and sperm motility and morphology in men with spinal cord injury.

OBJECTIVE: To assess the generation of reactive oxygen species and its relation to semen characteristics in men with spinal cord injury. DESIGN: Cross-sectional study. SETTING: Andrology laboratory at a tertiary care facility and research laboratory at a major medical center. PATIENT(S): Men with spinal cord injury and normal men. INTERVENTION(S): Collecting ejaculates from men with spinal cord injury by electroejaculation and vibratory stimulation and from normal men by masturbation. MAIN OUTCOME MEASURE(S): Measurement of reactive oxygen species before and after stimulation with 50 microM N-formyl-methionyl-leucylphenylalanine (FMLP) and 100 nM 12-myristate 13-acetate phorbol ester (PMA), white blood cell (WBC) concentration, sperm motility and morphology, and ejaculation method. RESULT(S): Compared with controls, levels of reactive oxygen species in men with spinal cord injury were significantly higher in unstimulated, f-MLP-stimulated, and PMA-stimulated specimens. The WBC concentration was significantly elevated in patients with spinal cord injury. Sperm motility in men with spinal cord injury was inversely related to the level of reactive oxygen species. The percentage of morphologically normal spermatozoa was significantly lower in men with spinal cord injury. Levels of seminal reactive oxygen species did not differ when comparing specimen type (antegrade versus retrograde) or method of ejaculation in men with spinal cord injury. CONCLUSION(S): Men with spinal cord injury had elevated levels of reactive oxygen species in their semen. Levels of reactive oxygen species were negatively correlated with sperm motility. Levels of reactive oxygen species were independent of the method of ejaculation or the type of specimen.

Adult↗

Pheromonal influences on sociosexual behavior in young women.

A double-blind, placebo-controlled study of a synthesized putative female pheromone was conducted with regularly menstruating, university women (N=36, mean age=27.8). The pheromone formula was derived from earlier work investigating the underarm secretions of fertile, sexually active, heterosexual women. A vial of either synthesized pheromone or placebo was selected blindly and added to a subject's perfume. Subjects recorded seven sociosexual behaviors and reported them weekly across three menstrual cycles. Beginning with Day 8 of each cycle, the first cycle contained a 2-week baseline period followed by an experimental period of as many as 3 weeks each from the next two cycles for a maximum of 6 weeks. The 19 pheromone and 17 placebo subjects did not differ significantly in age, weight, body mass index, dating status or ethnicity nor in reported accuracy, back-filling data, perception of a positive effect or perfume use. Placebo subjects were significantly taller than pheromone subjects. Except for male approaches, subjects did not differ significantly at baseline in average weekly sociosexual behaviors. A significantly greater proportion of pheromone users compared with placebo users increased over baseline in frequency of sexual intercourse, sleeping next to a partner, formal dates and petting/affection/kissing but not in frequency of male approaches, informal dates or masturbation. Three or more sociosexual behaviors increased over baseline for 74% of pheromone users compared with 23% of placebo users. We conclude that this synthesized pheromone formula acted as a sex attractant pheromone and increased the sexual attractiveness of women to men.

Adult↗

Attitudes of French adolescents toward sexuality.

Three hundred and eighty-six French adolescents from 16 to 18 years of age (145 boys and 241 girls) were questioned about sexuality. The five questions used covered their opinions on: abortion, masturbation, sexual intercourse during adolescence, homosexuality and marriage. The comparison of their responses to the five questions was expected to bring out the differences in their reactions in these areas. In fact, the results revealed that the subjects were not concerned to the same degree by the five questions. It was also observed that few adolescents were completely "liberal" and even fewer completely "conservative". The importance of socio-cultural factors, especially religion, associated with the attitudes of the subjects appeared undeniable. Some interesting differences in attitudes expressed by the two sexes were brought out.

Abortion, Induced↗

[Genital and sexual manifestations occurring in the course of partial seizures in man (author's transl)].

The literature only rarely mention the genital and sexual manifestations occurring in the course of partial seizures in man. The authors presently describe 42 seizures of this type recorded with E.E.G. and Stereo-E.E.G. techniques in 15 patients. The results of this study indicate that the genital and sexual paroxystic manifestations do have a specific semeiology, and there can be related to the initial localization of the electrical discharge which may begin in one of three different regions (perisylvian region, anterior part of the cingular gyrus and the paracentral lobule). Penile erection is observed in only one seizure starting in the central region. Orgasm occurs in the only one female patient in the course of the seizures beginning in the perisylvian region (temporal region). Early sensitive symptomatology characterizes very often the seizures beginning in the perisylvian region but also in the paracentral lobule. Post-ictal or peri-ictal true masturbation occurs at the end of the ictal discharge beginning either in the perisylvian region or in the anterior part of the cingular gyrus. The sexual dyspraxic (i.e. fondling the genitals) characterizes only the post-ictal phase of the seizures beginning in any of the three regions.

Adolescent↗

Genetic and environmental influences on problematic masturbatory behavior in children: a study of same-sex twins.

Child sexual behavior problems, such as excessive or public masturbation, are often judged to result from environmental stress or trauma. We studied the relative importance of genetic and environmental factors for problematic masturbatory behavior among nonreferred prepubertal children. All twins born in Sweden in 1985-86 were identified from the Swedish Twin Registry. Parents, mainly mothers, completed Child Behavior Checklist (CBCL) ratings (Achenbach, 1991) for 401 monozygotic (MZ) and 248 dizygotic (DZ) same-sex twin pairs (male-male or female-female) at age 7-9 years. Scores of two CBCL items concerning specific sexual behavior problems (Plays with own sex parts in public and Plays with own sex parts too much) were summed and the influence of genetic and environmental factors on variability assessed. The prevalence of problematic child masturbatory behavior was low and associated with other emotional and behavioral problems. The degree of problematic child masturbatory behavior resemblance was higher within MZ twin pairs as compared to DZ same-sex twin pairs. Model fitting indicated that genetic factors substantially influenced the studied behaviors (77%, 95% CI = 9-96%), although family environment also played a role. Our results suggest that hereditary factors should be considered together with stressful experiences such as sexual victimization in the evaluation of elementary school children presenting with problematic masturbatory behaviors. When interpreting the findings, the very brief measure of sexual problem behavior and low statistical power, precluding the analysis of possible coinheritance with other symptoms or disorders, should be borne in mind.

Child↗

Dimensions of subjective female orgasmic responsiveness.

Results of recent psychological research have been at odds with the major physiological evidence on the nature of female orgasmic responsiveness. Although female orgasm appears to be a single process physiologically, subjective reports by women indicate that individual differences in their experience is multidimensional. The basis for the discrepant findings is analyzed via two studies of reported orgasmic experiences in women. One sample of 115 sexually experienced women yielded data that replicated the finding that coital and masturbatory orgasmic responsiveness can be statistically distinguished and independently assessed, thus indicating that sample selection associated with prior research could not explain the result. A separate sample of 101 sexually experienced women were given an instrument that assessed coital responsiveness but differentiated masturbatory responsiveness into dimensions associated with masturbation when alone and with a partner without intercourse. A confirmatory factor analysis substantiated the existence of the three dimensions of female orgasm. However, female orgasmic responsiveness was highly correlated across the three dimensions so that it was possible to isolate a large second-order factor of general orgasmic responsiveness that is consistent with most of the physiological evidence on the unitary nature of orgasm. Correlates of the orgasm scales with background data revealed some discriminant validity for the three dimensions of responsiveness.

Adolescent↗

Fracture of the penis.

BACKGROUND: Sporadic reports of penile fracture give the impression of a rare trauma. The value of diagnostic investigations is doubtful and treatment options are controversial. METHODS: A Medline search from January 1966 to July 2001 using the terms 'fracture of penis', 'penile trauma' and 'coital injuries' was used to identify full texts of publications on fracture of the penis. Full texts of relevant references from these publications were also identified. Data extracted for review included authors, country and year of publication, number of cases in each report, aetiology, clinical features, investigations, treatment and outcome. RESULTS: In 183 publications 1331 cases were reported between January 1935 and July 2001. Most reports were from the Mediterranean region. The commonest causes were coitus and penile manipulations, especially masturbation. Most patients were in their fourth decade. Clinical features included sudden penile pain, detumescence, voiding difficulties, and penile swelling and deviation. Diagnosis was made mainly on clinical grounds. Associated injuries included urethral rupture. Predisposing factors included excessive force at coitus or manipulation, fibrosclerosis of the tunica albuginea and chronic urethritis. Most authors advocated early surgical repair using absorbable sutures. Complications of the injury included coital difficulty, urethral fistula, penile plaque and erectile dysfunction. CONCLUSION: Penile fracture is not rare. Radiological investigations are expensive and may delay treatment. Current management favours early surgical exploration to prevent complications.

Adolescent↗

Fracture of the penis: nine cases with evaluation of reported cases in Japan.

BACKGROUND: Fracture of the penis is a relatively rare condition that is defined as a rupture of the tumescent corpora cavernosa as a result of blunt trauma, most commonly during sexual intercourse or masturbation. The fracture is easy to recognize but treatment remains controversial. We, therefore, examined the treatment methods for penile fracture. METHODS: Between December 1990 and March 2001, eight patients underwent immediate surgical repair on the first or second day after fracture of the penis, and one patient underwent surgery on the 30th day after fracture, at Kansai Rosai Hospital. Patient age at presentation ranged from 15 to 55 years. Eight patients came to the hospital 2-23 h after the fracture occurred. All patients complained of penile swelling and ecchymosis. Three patients reported hearing a snapping sound. None of the patients demonstrated macroscopic hematuria. RESULTS: We treated all of the patients surgically. All patients showed a unilateral injured corporeal rupture. We took a circumferential coronal incision under the glans and repaired with absorbable stitch. At follow-up, eight of the nine patients who were available reported the achievement of an adequate erection for intercourse without erectile or voiding dysfunction. CONCLUSION: All patients were treated surgically and recovered successfully. Therefore, immediate repair is recommended for the treatment of penile fracture.

Adolescent↗