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Gender differences in pain ratings and pupil reactions to painful pressure stimuli.

In order to investigate gender differences in pain perception, the present study employed both a psychophysical and a psychophysiological measure. In experiment 1, 20 subjects rated the painfulness of 4 different levels of tonic pressure applied to their fingers using a verbally anchored categorization procedure. In general agreement with studies of pain threshold and tolerance, female subjects reported greater pain at high levels of stimulation, with no gender difference being evident at low pressure levels. In experiment 2, 16 different subjects were exposed to the same painful pressure stimuli while measuring their pupil reactions using infrared video pupillometry. The pupil dilations seen during the last 10 sec of the 20-sec pressure application turned out to be a highly significant indicator of pain intensity. When female and male subjects were compared on this measure, a similar divergent pattern as in the psychophysical data emerged, with female subjects showing greater pupil dilations at high pressure levels only. The fact that gender differences in pain perception can be demonstrated using an autonomic indicator of pain that is beyond voluntary control suggests that these differences reflect low-level sensory and/or affective components of pain rather than attitudinal or response-bias factors.

Female↗

Gender differences in psychological distress among Southeast Asian refugees.

The focus of this study was to examine gender differences in levels and predictors of psychological distress in a community sample of Southeast Asian refugees. Although previous studies with clinical samples of Southeast Asian refugees have found gender differences in the degree of psychological distress, the few community-based studies have been inconclusive. This community study found that there were gender differences in the predictors of distress and that refugee women reported significantly higher levels of psychological distress than their male counterparts. Implications of the findings are discussed.

Adaptation, Psychological↗

[Gender differences in cognitive functions and influence of sex hormones].

OBJECTIVE: To review scientific evidence on gender differences in cognitive functions and influence of sex hormones on cognitive performance. METHOD: Systematical search of related studies identified in Medline. RESULTS: Women outperform men on verbal fluency, perceptual speed tasks, fine motor skills, verbal memory and verbal learning. Men outperform women on visuospatial ability, mathematical problem solving and visual memory. No gender differences on attention and working memory are found. Researchers distinguish four methods to investigate hormonal influence on cognitive performance: a) patient with hormonal disorders; b) neuroimaging in individuals during hormone administration; c) in women during different phases of menstrual cycle, and d) in patients receiving hormonal treatment (idiopathic hypogonadotropic hypogonadism, postmenopausal women and transsexuals). The findings mostly suggest an influence of sex hormones on some cognitive functions, but they are not conclusive because of limitations and scarcity of the studies. CONCLUSIONS: There are gender differences on cognitive functions. Sex hormones seem to influence cognitive performance.

Adult↗

Gender differences in health and risk behaviors among bisexual and homosexual adolescents.

OBJECTIVE: This study explored gender differences in the health and risk behaviors of 394 self-identified bisexual and homosexual adolescents who participated in an anonymous, school-based survey. METHODS: Respondents included 182 girls and 212 boys; girls were significantly younger than boys (p < 0.001), so respondents were further grouped as younger (< or =14 years) and older (> or =15 years) for analysis. Chi-square was used to test for gender differences in health perceptions and risk behaviors. Items included general health perceptions and health care access, body image and disordered eating behaviors, sexual behaviors, alcohol use, and emotional health measures including mood, life satisfaction, and suicidal ideation and attempts. RESULTS: Both younger and older girls were significantly more likely than their male age mates to report a history of sexual abuse, dissatisfaction with weight, a negative body image, more frequent dieting, and an earlier age at onset of sexual intercourse. Both younger and older boys were significantly more likely than girls to have a positive body image, to rate themselves as healthier than peers, to report no regular source of health care, to be sexually experienced, and to drink alcohol more often and in greater quantity; a significantly greater proportion of older boys than older girls reported alcohol use before school (19.0% vs. 3.9%; p < 0.05). No significant gender differences were found for measures of emotional health, including suicidal ideation and attempts; however, nearly 1 of 3 older boys and girls reported at least one suicide attempt. CONCLUSIONS: Gender is a substantive source of variation in health and risk behaviors among bisexual and homosexual adolescents. Health care providers should incorporate gender-specific approaches to health promotion and risk reduction with young people who self-identify as gay, lesbian, or bisexual.

Adolescent↗

Gender differences in the dynamics of terminal T wave intervals.

This study was designed to investigate gender differences in the dynamic changes of the terminal T wave (Ta-e interval) of healthy subjects. Holter ECGs were recorded in 24 healthy volunteers (12 men aged 23 +/- 2 years). The intervals from QRS onset to the apex (QaT) and to the end of the T wave (QeT), and the interval between the apex and the end of the T wave (Ta-e) were measured. Then, the QeT/RR, QaT/RR, and Ta-e/RR relationship was evaluated by linear regression analysis in each subject. The QeT and QaT intervals were significantly longer in women than men and the slope of the QeT/RR and QaT/RR relationship was steeper in women than men. The Ta-e intervals showed a significant but weaker positive correlation with the preceding RR intervals in 7 (58.3%) men and 9 (75.0%) women. The average values of the slope and the correlation coefficient of the Ta-e/RR relationship were significantly smaller compared to those of QeT and QaT in both men and women (P < 0.0001). The slope of the Ta-e/RR relationship was significantly greater in women than men (0.025 +/- 0.009 vs 0.011 +/- 0.012, P < 0.005). However, the Ta-e intervals were significantly longer over the entire range of RR intervals in men than women (P < 0.0001). The rate-correcting formulas of Bazett and Framingham overcorrected the Ta-e intervals. The observed gender difference in the measurement and dynamics of the Ta-e interval may help to understand the mechanisms underlying the gender difference in the incidence of ventricular arrhythmias.

Adult↗

Gender differences in the relations between work-related physical and psychosocial risk factors and musculoskeletal complaints.

Gender differences in the prevalence of musculoskeletal complaints might be explained by differences in the effect of exposure to work-related physical and psychosocial risk factors. A systematic review was conducted to examine gender differences in the relations between these risk factors and musculoskeletal complaints. Several electronic databases were searched. The strength of the evidence was determined on the basis of the methodological quality and consistency of the study results. For lifting, strong evidence was found that men have a higher risk of back complaints than women. The same was found for the relation between hand-arm vibration and neck-shoulder complaints. For arm posture, strong evidence was found that women have a higher risk of neck-shoulder complaints than men. For social support, no evidence of a gender difference was found for either neck-shoulder or back complaints. For hand-wrist and lower-extremity complaints, inconclusive evidence was found due to a lack of high-quality studies.

Evidence-Based Medicine↗

Does type of disease matter? Gender differences among Alzheimer's and Parkinson's disease spouse caregivers.

PURPOSE OF STUDY: Mental health outcomes are widely reported among spouse caregivers, with wives generally faring worse than husbands. We hypothesized that gender differences would not be as strong in a cognitively intact group because caring for cognitively intact spouses may involve less severe reciprocity losses. We also examined gender differences in coping strategies within each group. DESIGN AND METHOD: 175 spouse caregivers for patients with Alzheimer's disease (AD; n = 88) and Parkinson's disease (PD; n = 87) were interviewed. Participants completed perceived stress (PSS), depression (CES-D), state anxiety (STAI, Form Y), and coping strategies (WCCL-R) measures. RESULTS: Wives in the AD group reported significantly worse mental health outcomes than husbands, while wives and husbands in the PD group showed no differences. AD caregiving wives were less likely than husbands to use problem-focused coping strategies. There were no significant gender differences in either group for social support or emotion-focused coping. IMPLICATIONS: Loss of reciprocity in marital relationships may affect women more negatively than men. Future studies that address underlying mechanisms of gender differences and focus on similar caregiving situations and contexts deserve attention.

Adaptation, Psychological↗

Gender differences in implicit weight identity.

OBJECTIVE: This study examined gender differences in explicit and implicit attitudes toward overweight and explicit and implicit weight identity. METHOD: Normal weight women (n=22) and men (n=20) and overweight women (n=20) and men (n=21) completed the Implicit Association Test and portions of the Eating Disorders Questionnaire. RESULTS: Although explicit and implicit anti-fat attitudes were ubiquitous, gender differences emerged for weight identity. Both men and women provided accurate explicit appraisals of their weight status. However, men implicitly identified themselves as light regardless of actual weight status. Women's implicit weight identity was associated with their actual weight status, explicit weight appraisal, and implicit self-esteem. DISCUSSION: These findings may provide additional insight into why men are underrepresented among those seeking weight loss and why women are at increased risk for developing eating disorders.

Adult↗

Gender differences in self-reported physical and psychosocial exposures in jobs with both female and male workers.

OBJECTIVE: The aim was to determine whether men and women with the same job are equally exposed to work-related physical and psychosocial risk factors for musculoskeletal complaints. METHODS: Men (n = 491) and women (n = 342) in 8 jobs with both female and male workers completed a questionnaire on exposure to work-related risk factors. Gender, job title, and potential confounders were included in the final statistical models. Separate analyses were performed for desk workers and assembly workers. RESULTS: For most risk factors gender differences in exposure were found. Among desk workers exposures were most often higher for women, which was the opposite for assembly workers. CONCLUSIONS: Although exposure assessment relied on self-report, it seems unlikely that gender differences in reporting behavior completely explained gender differences in exposure. Thus, gender differences in exposure are present within the same job.

Adult↗

Gender differences in the source and level of self-esteem of Chinese college students.

This research examined possible gender differences in the source and level of self-esteem of 99 male and 90 female undergraduates from mainland and China. There was little evidence of a gender difference in the level of overall self-esteem, but gender differences were evident in the subjects' ratings of the importance to their self-concept and their self-satisfaction with lower order facets of the self, indicating the necessity for using multidimensional measures of the self and for preserving the self-concept/self-esteem distinction.

Adult↗

Gender differences in treatment response to sertraline versus imipramine in patients with nonmelancholic depressive disorders.

There is evidence of gender differences in depressive disorders in terms of epidemiology and clinical manifestations. However, few studies have addressed the gender differences in terms of antidepressant treatment response in clinical practice. The aim of this study was to examine gender differences in the acute antidepressant response to sertraline and imipramine in nonmelancholic depressive disorders. A total of 239 patients with nonmelancholic major depression or dysthymia (DSM-III-R) and a score of >/=18 at baseline on the Hamilton Depression Rating Scale (HAM-D) were randomised in a 1:1 ratio treatment with flexible doses of sertraline (50-200 mg/day) or imipramine (75-225 mg/day) for 8 weeks in a multicenter, randomised, open-labeled, parallel group comparative trial. Depressive and anxiety symptoms were assessed using the HAM-D and the Hamilton Anxiety Rating Scale (HAM-A). Using HAM-D criteria, women were significantly more likely to respond to sertraline than to imipramine (72.2% vs. 52.1%, P=.008), whilst men respond similarly to sertraline and to imipramine (56.5% vs. 59.3%, P>.05). Response analysis based on HAM-A shows similar results (women: 68.9% vs. 43.6%, P=.001; men: 56.5% vs. 51.9%, P>.05). Women taking sertraline show statistically significant higher reductions in HAM-D, HAM-A, and in CGI-S than women taking imipramine. The proportion of women who dropped out due to adverse events was much lower in sertraline than in imipramine (10.9% vs. 27.8%, P=.006), with no differences between treatments in men (8.3% vs. 11.5%, P>.05). It was concluded that sertraline is more effective and better tolerated than imipramine in the acute treatment of nonmelancholic depressive disorders in women, whereas men responded similarly to sertraline and to imipramine.

Antidepressive Agents, Second-Generation↗

Characterization of the mechanisms involved in the gender differences in p-aminohippurate renal elimination in rats.

Gender differences in the renal handling on drugs and toxins have received too little attention. In the present study, a variety of preparations were used to examine the basis for the greater effectiveness of the male kidneys in the elimination of p-aminohippurate (PAH) in rats. Renal clearance of PAH was significantly lower in female rats as consequence of its smaller filtered and secreted load. The gender difference in the filtered load may be accounted for the lower value of glomerular filtration rate (GFR) displayed by female rats as compared with males. The lower value of the renal blood flow observed in females might explain, at least in part, the decrease in the GFR and in the secreted load of PAH. In females, maximal uptake for PAH transport into renal basolateral membrane vesicles decreased to 52+/-9% (P < 0.05) and Michaelis-Menten constant for PAH uptake into renal brush border membrane vesicles was increased to 163+/-8% (P < 0.05). These changes might also explain the lower secreted load of PAH. The sex difference in the renal clearance of PAH was also evidenced by the reduced systemic clearance observed in female rats.

Animals↗

Gender differences in mental rotation.

Two experiments were carried out to compare the performance of male and female students at different educational levels on tasks that required mental rotation. Exp. 1 also compared their performance on an overt, male-typed version and a disguised, female-typed version of the same task. Amongst introductory undergraduate students, men performed significantly better than women, but this difference was as pronounced on the disguised, female-typed version as on the overt, male-typed task. However, there was no sign of any gender difference on the overt task in advanced undergraduate and postgraduate students. The latter finding was not replicated in Exp. 2, in which significant effects of gender regardless of the students' educational level were noted. Nevertheless, the effect size was significantly smaller than that obtained for comparable students tested on the same task during the 1970s. Taken together, these results confirm that gender differences in at least some aspects of mental rotation may be abolished by educational experience and that gender differences in mental rotation have become smaller over the last 20 years. Such findings favor sociocultural explanations of gender differences in mental rotation rather than biological explanations.

Adult↗

Professional education and practice arrangements: are there gender differences among paediatric dentists in Israel?

AIM: To assess gender differences in professional education, practice setting and working arrangements among dentists in Israel, who primarily treat children. SUBJECTS: All 112 participants in the meeting of the Israeli Society of Dentistry for Children that was held in February 1999. METHODS: A questionnaire completed during the meeting. RESULTS: Seventy participants (63 per cent) completed the questionnaire and returned it. There were 43 females and 27 males. Less than half of the population were specialists (40 per cent of the females, 48 per cent of the males). No significant differences were found in the educational background and working in academia between females and males. With regard to practice arrangement, males significantly reported more frequently working in two clinics or more, than females (P = 0.049), and working in clinics with general practitioners (GPs) and specialists in various fields in dentistry, while more women reported working with either GPs or specialists (P = 0.007). In all other variables, no significant gender differences were found. The results of our study show that paediatric dentistry in Israel appears as a branch of the profession which shows great sexual equality of opportunity.

Adult↗

The influence of work, household structure, and social, personal and material resources on gender differences in health: an analysis of the 1994 Canadian National Population Health Survey.

Data from the 1994 Canadian National Population Health Survey (NPHS) do not confirm the widespread assumption that women experience considerably more ill health than men. The patterns vary by condition and age and at many ages, the health of women and men is more similar than is often assumed. However, we should not minimize the gender differences that do exist and in this paper we focus on three health problems which are more common among women: distress, migraine and arthritis/rheumatism. We consider to what extent work, household structure and social, personal and material resources explain these gender differences in health. Analysis of the distributions of paid work conditions, household circumstances and resources reveal mostly minor differences by gender and differences in exposure to these circumstances contribute little to understanding gender differences in health. There is also little evidence that greater vulnerability is a generalized health response of women to paid and household circumstances. We find limited evidence that social, personal and material resources are involved in pathways linking work and home circumstances to health in ways that differ between the sexes. In conclusion, we consider some reasons for the lack of support for our explanatory model: the measures available in the NPHS data set which contains little information on the household itself; the difficulty of separating 'gender' from the social and material conditions of men's and women's lives; and changes in women's and men's roles which may have led to a narrowing of differences in health.

Adolescent↗

Gender differences in pain: do emotions play a role?

BACKGROUND: Research suggests that the influence of gender on the processing and experience of pain is a result of several mechanisms. One mediating variable is emotion, which may modulate pain through an interaction of valence (pleasant-unpleasant) and arousal (calm-excited). OBJECTIVE: This review examines whether gender differences in the experience and processing of emotion contribute to differences in the modulation and perception of pain. METHODS: An English-language search of MEDLINE and PsycINFO was conducted from 1887 to May 2005. Additional literature was obtained from reference lists of articles retained in the initial search. RESULTS: Emotion appears to influence pain through a valence-by-arousal interaction. Specifically, negatively valenced emotions with low to moderate arousal (eg, anxiety) enhance pain, whereas negatively valenced emotions with high arousal (eg, fear) reduce pain. In contrast, positively valenced emotions always reduce pain, as long as minimal arousal is achieved. Some evidence suggests that women are more sensitive than men to threat-related stimuli and thus experience more negative affect than men. This would generally lead to enhanced pain perception in women. It is also possible that women are more likely than men to experience negative affect with high arousal (intense fear) and thus pain inhibition. However, the relatively lower base rate of intense negative emotions is not likely to contribute much to gender differences in pain. Evidence also suggests that men may be more sensitive to positive events, particularly sexual/erotic stimuli, which may lead to more positive emotion-induced pain reduction in men, relative to women. CONCLUSIONS: This review suggests that gender differences in the experience of pain may arise from differences in the experience and processing of emotion that, in turn, differentially alter pain processing. Specifically, the system associated with negative affect may be more attuned to threatening stimuli in women, and the system associated with positive affect may be more attuned to pleasurable stimuli in men. However, there is a paucity of research directly addressing this issue; much of the research on this topic has failed to test a comprehensive model of emotion, failed to use adequate manipulation checks, or failed to use within-subject experimental designs that control for intra- and interindividual differences. Therefore, it is concluded that additional research is warranted.

Animals↗

Gender differences in amino acid use during endurance exercise.

There are gender differences in the substrate used to fuel prolonged physical activity. Males rely on carbohydrate and amino acids (97%), while females use predominantly fat (62%) to fuel endurance exercise. This review looks at the mechanisms that regulate these gender differences, with a focus on amino acid metabolism. Gender-selective nutritional recommendations are indicated for physically active individuals and some cardiac patients who engage in intense aerobic activity.

Adipose Tissue↗

Gender differences in physical activity and physical fitness in young children in Crete.

BACKGROUND: To assess physical activity and physiological fitness parameters among six year old children and to determine whether there were any significant gender differences. METHODS DESIGN & SETTING: comparative study of a representative sample of boys and girls in school and at home. PARTICIPANTS: 569 children (305 boys and 264 girls) selected randomly from a total of 6153 registered in the 1st grade in 1992 on the island of Crete. MEASURES: assessment of physical activity was based on observational methods involving teachers and parents. Cardiorespiratory fitness was estimated by performance on the 20 meter Shuttle Run Test (20mSRT). BMI, skinfold thickness, Midarm Muscle Circumference (MMC) and hemoglobin were also measured. RESULTS: Both sexes were found to spend a very small proportion of their leisure time in Moderate to Vigorous Physical Activities (MVPA). More boys engaged in MVPA than girls at school and at home, but more girls were involved in physical activity-related lessons and classes out of school. Among the physiological fitness parameters, significant gender differences were found only for MMC. No significant gender difference was found in performance on the 20mSRT. CONCLUSIONS: The results indicate that in this culture stereotypic sex preferences in physical activity begin at a very young age, and that this differentiation cannot be attributed to gender differences in cardiorespiratory fitness. The social, environmental and possibly psychological parameters involved have implications for Health Educators and Physical Education Instructors in the appropriate targeting of physical activity promotion programs among young children.

Anthropometry↗