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At least 379 records · Page 21Linked to original sources
PubMed1992

A miniaturised force-torque sensor with six degrees of freedom for dental measurements.

Force-torque sensor systems capable of simultaneously measuring all six spatial degrees of freedom on solid bodies are not very widespread in the medical field, particularly because of the hitherto unacceptably large external dimensions. A sensor based on the strain gauge technique has been developed with a diameter of only 32.5 mm and height of 29 mm. The miniaturised supporting framework for the strain gauges has been cast in a single piece from a wax-plastic model by the one-way mould principle. A sensitivity of 10 mN with an upper limit of 50 N is attained.

Crowns↗
PubMed2005

Six-degrees-of-freedom sensing based on pictures taken by single camera.

Two six-degrees-of-freedom sensing methods are presented. In the first method, three laser beams are employed to set up Descartes' frame on a rigid body and a screen is adopted to form diffuse spots. In the second method, two superimposed grid screens and two laser beams are used. A CCD camera is used to take photographs in both methods. Both approaches provide a simple and error-free method to record the positions and the attitudes of a rigid body in motion continuously.

Dental Articulators↗
PubMed1975

Society of the alone: Freedom, Privacy and Utilitarianism as dominant norms in the SRO.

The social world of the aged SRO tenant is described and analyzed. Charteristic features include an impoverishment of social roles and relationships which result in a "world of strangers". Dominant norms of SRO life which preclude the establishment of intimacy are examined; these include prescriptive norms of privacy, freedom, and utilitarianism

Aged↗
PubMed1994

Personal freedom and responsibility: the ethical foundations of a market-based health care reform.

The current health care system is not operating with a properly functioning market. Health care costs are hidden and often shifted, consumers and providers are insulated from the economic consequences of their decisions, and costs therefore go up dramatically. Instead of attacking both the structural deficiencies and the consequent inequities of the current employer based insurance system, the Clinton Plan simply expands them, and adds a heavier level of government regulation. The ultimate choice for the public is between a health care system based on consumer choice or a government controlled system. In pursuing a market based health care reform that enhances personal freedom and responsibility, two ethical principles are served. First, American consumers will be made aware of the true costs of health care services, and market forces will thus introduce incentives on the part of providers to control costs. Second, justice will be served; for not only will providers of medial services receive their due, but public policy makers can target relief more effectively to those who need it most.

Ethics↗
PubMed2003

Beyond individual rights and freedoms: metaethics in social work research.

Increasingly, social workers are called on to demonstrate the efficacy of their interventions and to contribute to knowledge building in the social sciences. Although social workers have a long tradition of practice ethics, less attention has been given to the unique dimensions of research ethics for social workers. A social work model of research ethics would consider how to balance highly valued ethical principles that are individually focused, such as self-determination and nonmalfeasance (the obligation to do no harm), with equally important values that have a collective focus, such as justice and beneficence (the obligation to bring about good). This article reviews current principles guiding research ethics, such as autonomy, beneficence, nonmalfeasance, and justice and provides an outline of the salient issues for social workers as they strive to address individual and collective interests in research endeavors, such as a greater emphasis on the social justice mission and the need to ensure that social justice objectives do not obscure individual rights and freedoms. The article concludes with preliminary recommendations for developing a social work perspective in research ethics.

Codes of Ethics↗
PubMed1999

The third factor of the WISC-III: it's (probably) not freedom from distractibility.

OBJECTIVE: This study examined the ecological validity, construct validity, and diagnostic utility of the third factor of the WISC-III, heuristically labeled "Freedom From Distractibility" (FFD). METHOD: A sample of 200 children, aged 6 to 11 years, with attention-deficit hyperactivity disorder (ADHD) completed the WISC-III, the Wide Range Achievement Test-Revised, and the Test of Variables of Attention. Objective parent and teacher report measures of attention and hyperactivity were completed. RESULTS: Mean FFD scores were significantly lower than other WISC-III factor scores. The diagnostic utility of FFD is limited, however, as the majority of these children did not show a significant relative weakness on this index. Correlational analyses failed to support the concurrent, ecological, or construct validity of the FFD. FFD scores were not correlated with a measure of sustained visual attention. Findings suggest that among children with ADHD, a low FFD score may be associated with the presence of a learning disability or poor academic performance. This finding was maintained after level of general intelligence was statistically controlled. CONCLUSIONS: Clinicians and researchers should not view FFD as a reliable or valid index of attention or as a diagnostic screening measure for identifying children with ADHD.

Achievement↗
PubMedDate not supplied

The dialectic of freedom and accountability: balancing faculty work load.

A work load standard for faculty assignments was developed and described in the previous article by Freund. In this article, the authors discuss use of the standard for distributing the work of the school while allowing time for service activity and faculty scholarship. While allocating responsibility according to a formula is a rational approach to work load assignment and evaluation, it raises a number of issues which the authors discuss in relation to individual freedom and organizational accountability.

Employee Performance Appraisal↗
PubMed1999

Peak cyclosporine levels (Cmax) correlate with freedom from liver graft rejection: results of a prospective, randomized comparison of neoral and sandimmune for liver transplantation (NOF-8).

BACKGROUND: Despite two decades of use, there are limited data on the best way to administer and monitor cyclosporine (CsA) for liver transplantation. The present study was undertaken (1) to determine whether treatment with a new formulation of CsA, Neoral, would improve the results of liver transplantation; and (2) to study the relationships between pharmacokinetic parameters and clinical outcomes after transplantation. METHODS: A double-blind, randomized, comparison of Sandimmune (SIM) with Neoral (NEO) was conducted at five Canadian centers in 188 consecutive adults undergoing primary orthotopic liver transplantation. Patients were induced with intravenous CsA then switched to NEO or SIM. Dose adjustments were made daily, or as needed, to reach a target trough CsA level of 350 ng/ml in both groups. Pharmacokinetic studies were performed on days 5, 10, 15, and 16 weeks after transplantation. RESULTS: The NEO group was slightly younger, with a median age of 50 years (range: 23-70) versus 55 years (range: 24-71) for SIM (P = 0.007); otherwise the two groups were well balanced. The NEO group stopped intravenous CsA earlier (5.8+/-2.6 days vs. 8.7+/-4.7 days, P<0.0001). This group required a lower median daily oral dose (7.5 mg/kg vs. 9.0 mg/kg, P<0.01) to maintain comparable trough CsA levels. Five SIM patients, but no NEO patients, discontinued the study due to the inability to reach target trough levels of CsA within the prescribed time (P<0.05). At 4 months, there were no differences between the two groups with respect to patient survival (93% NEO vs. 91% SIM), graft survival (90% NEO vs. 86% SIM), and rejection-free survival (54.1% NEO, 51.8% SIM). The incidence of serious adverse events was also similar and did not correlate with CsA pharmacokinetic profiles. The NEO group had a higher area under the drug concentration curve for the first 6 hr after the dosing interval (AUC0-6) and peak CsA levels (Cmax). There was a strong correlation between freedom from graft rejection during the first month after transplantation and (a) AUC0-6 and (b) Cmax at days 5 and 10 after transplantation, but only in the NEO group did this reach statistical significance. In contrast, there was a poor correlation between trough CsA and graft rejection. In patients on NEO, the concentration of CsA 2 hr after dosing (C2) closely reflected AUC0-6 (r2 = 0.93), whereas there was a poorer correlation in patients on SIM (r2 = 0.73) CONCLUSIONS: Cmax and/or AUC0-6 may provide better markers than trough levels for monitoring CsA-based immune suppression after orthotopic liver transplantation. Prospective studies are underway to determine whether dosing to C2, which provides a good estimation of Cmax, can be used to take full advantage of NEO's improved absorption profile.

Adult↗
PubMedDate not supplied

Sequential classification of endocrine stages during reproductive aging in women: the FREEDOM study.

OBJECTIVE: Reproductive aging involves complex endocrine changes affecting women's fertility, health, and well-being; however, understanding of the specific changes involved is limited by the lack of detailed quantitative studies. We undertook a thorough study with the aim of characterizing the different endocrine stages involved in female reproductive aging. DESIGN: FREEDOM is a cohort study designed to determine the endocrine changes during reproductive aging in women. Here, we ascertained the different endocrine patterns in a representative population and developed a staging system. In this study, 112 women aged 30 to 58 years collected daily urine samples over a 6- to 18-month period and recorded their menstrual periods. A total of 36,786 samples were analyzed for follicle-stimulating hormone (FSH), luteinizing hormone, estrone 3-glucuronide, and pregnanediol 3-glucuronide. RESULTS: A classification of five sequential endocrine stages of reproductive aging was developed: stage 1, regular menstrual cycles with mean initial (day 1-5) FSH less than 5 IU/L; stage 2, regular cycles with FSH greater than 5 IU/L; stage 3, menstrual irregularity (with the appearance of "delayed-response cycles"); stage 4, acyclical ovarian activity with no evidence of ovulation and luteinization; and stage 5, ovarian quiescence and persistently raised gonadotropins. Distinct hormonal characteristics during the follicular and luteal phase were noted at each stage. CONCLUSION: This classification provides a detailed insight into the endocrinology of reproductive aging in women that could be useful for both clinical guidance and personal health care.

Adult↗
PubMed2006

Tactical surgical intervention with temporary shunting of peripheral vascular trauma sustained during Operation Iraqi Freedom: one unit's experience.

BACKGROUND: Rapidly restoring perfusion to injured extremities is one of the primary missions of forward military surgical teams. The austere setting, limited resources, and grossly contaminated nature of wounds encountered complicates early definitive repair of complex combat vascular injuries. Temporary vascular shunting of these injuries in the forward area facilitates rapid restoration of perfusion while allowing for deferment of definitive repair until after transport to units with greater resources and expertise. METHODS: Standard Javid or Sundt shunts were placed to temporarily bypass complex peripheral vascular injuries encountered by a forward US Navy surgical unit during a six month interval of Operation Iraqi Freedom. Data from the time of injury through transfer out of Iraq were prospectively recorded. Each patient's subsequent course at Continental US medical centers was retrospectively reviewed once the operating surgeons had returned from deployment. RESULTS: Twenty-seven vascular shunts were used to bypass complex vascular injuries in twenty combat casualties with a mean injury severity score of 18 (range 9-34) and mean mangled extremity severity score of 9 (range 6-11). All patients survived although three (15%) ultimately required amputation for nonvascular complications. Six (22%) shunts clotted during transport but an effective perfusion window was provided even in these cases. CONCLUSION: Temporary vascular shunting appears to provide simple and effective means of restoring limb perfusion to combat casualties at the forward level.

Adolescent↗
PubMed2006

The experience of the US Marine Corps' Surgical Shock Trauma Platoon with 417 operative combat casualties during a 12 month period of operation Iraqi Freedom.

BACKGROUND: The Forward Resuscitative Surgical System (FRSS) is a small, mobile trauma surgical unit designed to support modern US Marine Corps combat operations. The experience of two co-located FRSS teams during 1 year of service in Operation Iraqi Freedom is reviewed to evaluate the system's efficacy. METHODS: Between March 1, 2004, and February 28, 2005, two FRSS teams and a shock trauma platoon were co-located in a unit designated the Surgical Shock Trauma Platoon (SSTP). Data concerning patient care before and during treatment at the SSTP was maintained prospectively. Prospective determination of outcomes was obtained by e-mail correspondence with surgeons caring for the patients at higher echelons. The Los Angeles County medical center (LAC) trauma registry was queried to obtain a comparable data-base with which to compare outcomes. RESULTS: During the year reviewed there were 895 trauma admissions to the SSTP. Excluding 25 patients pulseless on arrival and 291 minimally injured patients, 559 of 579 (97%) combat casualties survived; 417 casualties underwent 981 operative procedures in the two SSTP operating shelters. There were 79 operative patients with a mean injury severity score of 26 (range, 16-59) and mean revised trauma score of 6.963 (range, 4.21-7.841) who had sustained severe injuries. Ten (12.7%) of these casualties died while 43 of 337 (12.8%) deaths were seen with comparable cases treated at LAC. CONCLUSIONS: Small task-oriented surgical units are capable of providing effective trauma surgical care to combat casualties. Further experience is needed to better delineate the balance between early, forward-based surgical intervention and more prolonged initial casualty evacuation to reach more robust surgical facilities.

Adult↗
PubMed1999

Approximate renormalization-group transformation for Hamiltonian systems with three degrees of freedom.

We construct an approximate renormalization transformation that combines Kolmogorov-Arnol'd-Moser and renormalization-group techniques, to analyze instabilities in Hamiltonian systems with three degrees of freedom. This scheme is implemented both for isoenergetically nondegenerate and for degenerate Hamiltonians. For the spiral mean frequency vector, we find numerically that the iterations of the transformation on nondegenerate Hamiltonians tend to degenerate ones on the critical surface. As a consequence, isoenergetically degenerate and nondegenerate Hamiltonians belong to the same universality class, and thus the corresponding critical invariant tori have the same type of scaling properties. We numerically investigate the structure of the attracting set on the critical surface and find that it is a strange nonchaotic attractor. We compute exponents that characterize its universality class.

Journal Article↗
PubMed2000

Coherence measure in hamiltonian systems with many degrees of freedom

We study the phase space region of two- and three-dimensional lattices where a transition from chaotic to ordered dynamics takes place when the energy is lowered. In this region we find coexistence of degrees of freedom (DOF's), endowed with different levels of chaos. The analysis of this complex dynamical pattern requires the introduction of diagnostic tools suitable for a characterization of single DOF's: coherence angles and coherence times. We find that the coherence times-which give a measure of the time each DOF needs to relax to equilibrium-are roughly proportional to the inverse of the specific energy. This may be useful to evaluate the reliability of statistical results obtained in computer experiments performed on condensed matter systems at low energy.

Journal Article↗
PubMed2001

Mirror symmetry breaking through an internal degree of freedom leading to directional motion.

We analyze here the minimal conditions for directional motion (net flow in phase space) of a molecular motor placed on a mirror-symmetric environment and driven by a center-symmetric and time-periodic force field. The complete characterization of the deterministic limit of the dissipative dynamics of several realizations of this minimal model reveals a complex structure in the phase diagram in parameter space, with intertwined regions of pinning (closed orbits) and directional motion. This demonstrates that the mirror symmetry breaking, which is needed for directional motion to occur, can operate through an internal degree of freedom coupled to the translational one.

Journal Article↗
PubMed2002

Design degrees of freedom and mechanisms for complexity.

We develop a discrete spectrum of percolation forest fire models characterized by increasing design degrees of freedom (DDOF's). The DDOF's are tuned to optimize the yield of trees after a single spark. In the limit of a single DDOF, the model is tuned to the critical density. Additional DDOF's allow for increasingly refined spatial patterns, associated with the cellular structures seen in highly optimized tolerance (HOT). The spectrum of models provides a clear illustration of the contrast between criticality and HOT, as well as a concrete quantitative example of how a sequence of robustness tradeoffs naturally arises when increasingly complex systems are developed through additional layers of design. Such tradeoffs are familiar in engineering and biology and are a central aspect of the complex systems that can be characterized as HOT.

Journal Article↗
PubMed2004

Large-amplitude oscillations and chaos in a Hamiltonian plasma system with many degrees of freedom.

Taking the beam-plasma system as a reference Hamiltonian system with many degrees of freedom, the connection between the development of large amplitude oscillations and stochasticity of the system (measured through the time-dependent maximum Lyapunov exponent) is investigated. It is found that the development of self-consistent large amplitude oscillations occurs in correspondence with the onset of chaos, and is related to a well defined change of topology of the phase space of the system. It is also shown that in a (Hamiltonian) linearly stable regime the development of large amplitude oscillations can occur when weakly dissipative processes are introduced.

Journal Article↗
PubMed2005

Statistics of unstable periodic orbits of a chaotic dynamical system with a large number of degrees of freedom.

For a simple model of chaotic dynamical systems with a large number of degrees of freedom, we find that there is an ensemble of unstable periodic orbits (UPOs) with the special property that the expectation values of macroscopic quantities can be calculated using only one UPO sampled from the ensemble. Evidence to support this conclusion is obtained by generating the ensemble by Monte Carlo calculation for a statistical mechanical model described by a space-time Hamiltonian that is expressed in terms of Floquet exponents of UPOs. This result allows us to interpret the recent interesting discovery that statistical properties of turbulence can be obtained from only one UPO [G. Kawahara and S. Kida, J. Fluid Mech. 449, 291 (2001); S. Kato and M. Yamada, Phys. Rev. E 68, 025302(R) (2003)].

Journal Article↗
PubMed2005

Resonance-assisted tunneling in three degrees of freedom without discrete symmetry.

We study dynamical tunneling in a near-integrable Hamiltonian with three degrees of freedom. Despite the absence of discrete symmetry we show that the mixing of near-degenerate quantum states is due to dynamical tunneling mediated by the nonlinear resonances in the classical phase space. Identifying the key resonances allows us to selectively suppress the dynamical tunneling by adding weak counter-resonant terms.

Journal Article↗