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Gamma versus DHS nailing for extracapsular femoral fractures. Meta-analysis of ten randomised trials.

A meta-analysis has been carried out of all published randomised trials which compare the gamma with the DHS nail, giving in a total of 1794 patients with extracapsular femoral fractures. Results showed that the Gamma nail had a significantly increased risk of fracture of the femoral shaft and an increased reoperation rate. There was no difference in the lag screw cut-out rates, incidence of wound infection or length of stay in hospital. The gamma nail cannot be recommended for routine use in trochanteric fractures until the problem of femoral shaft fracture is resolved.

Aged↗

Nonoperative treatment of proximal femoral fractures in the demented, nonambulatory patient.

Two internists have recently championed the nonoperative, nonacute-care hospital management of demented nonambulatory elderly patients with proximal femoral fractures. They believe that superior care is thereby provided at lower cost and chances for survival improve. This article describes the problems encountered in applying nonoperative management to such patients in a different geographical setting, including the lack of accurate information about prefracture function, drastic alterations in patient health and function during transfers between institutions, difficulty even in recognizing fractures, the indefinite persistence of some pain, and lack of unanimity among treating professionals. Nonoperative management still remains a desirable option for truly nonambulatory, demented, aged patients with proximal femoral fracture. Triage should be done in the chronic care institution, but only by professionals who know the individual.

Aged↗

Periprosthetic femoral fractures around well-fixed implants: use of cortical onlay allografts with or without a plate.

BACKGROUND: Periprosthetic femoral fractures around hip replacements are increasingly common. When the femoral component is stable, open reduction and internal fixation is recommended in all but exceptional cases. The purpose of this study was to evaluate the outcome of treatment of fractures around stable implants with cortical onlay strut allografts with or without a plate. METHODS: A survey of our four centers identified forty patients with a fracture around a well-fixed femoral stem treated with cortical onlay strut allografts without revision of the femoral component. There were fourteen men and twenty-six women, with an average age of sixty-nine years. Nineteen patients were treated with cortical onlay strut allografts alone, and twenty-one were managed with a plate and one or two cortical struts. All of the patients were followed until fracture union or until a reoperation was done. The mean duration of follow-up was twenty-eight months for thirty-nine patients. One patient, who was noncompliant with treatment recommendations, had a failure at two months because of a fracture of the plate and graft. The primary end point of the evaluation was fracture union; secondary end points included strut-to-host bone union, the amount of final bone stock, and postoperative function. RESULTS: Thirty-nine (98%) of the forty fractures united, and strut-to-host bone union was typically seen within the first year. There were four malunions, all of which had <10 degrees of malalignment, and one deep infection. There was no evidence of femoral loosening in any patient. All but one of the surviving patients returned to their preoperative functional level within one year. CONCLUSIONS: Cortical onlay strut allografts act as biological bone plates, serving both a mechanical and a biological function. The use of cortical struts, either alone or in conjunction with a plate, led to a very high rate of fracture union, satisfactory alignment, and an increase in femoral bone stock at the time of short-term follow-up. Although this study did not address the potential for later allograft remodeling, our findings suggest that cortical strut grafts should be used routinely to augment fixation and healing of a periprosthetic femoral fracture.

Aged↗

Femoral fractures in a young male Turkey breeder flock.

Twenty-two 32-to-35-wk-old male turkeys from a commercial breeding flock were presented to the California Veterinary Diagnostic Laboratory System, Fresno Branch, with a clinical complaint of lameness and increased mortality. Necropsy findings included a unilateral, closed oblique fracture involving the femur in 12 birds. Ten complete femoral fractures had periosteal new bone adjacent to and bridging the fracture. Periosteal callus formation, in this case, suggested that preexisting lesions preceded complete fracture of the femur. Factors such as selection for heavy body weight, lack of exercise, and handling might have contributed to the development and promotion of complete fractures.

Animal Husbandry↗

Biomechanical characteristics of interlocking femoral nails in the treatment of complex femoral fractures.

Interlocking intramedullary (IM) nails allow more comminuted and proximal or distal femoral fractures to be successfully treated than previously possible with routine IM nailing. Autopsy specimens were prepared to evaluate the effectiveness of different locking mechanisms on fracture site stability. Grosse-Kempf (GK) and Brooker-Wills (BW) IM nails were inserted in anatomic specimen femurs with transverse fractures and 1-, 2-, and 3-cm defects. The femurs were loaded in four-point bending, and bending stiffness was calculated. The femurs were also loaded in torsion, and the amount of slippage between the nail and bone (at 10 Nm of applied torque) was measured. The GK nail, fully interlocked, had the lowest amount of rotational slip, followed by the BW and the GK noninterlocked nail. Bending stiffness was not significantly different for these IM nails.

Biomechanical Phenomena↗

The timing of surgery for proximal femoral fractures.

We studied prospectively a consecutive series of 765 patients with proximal femoral fractures to determine if the time interval between injury and surgery influenced the outcome. Patients in whom surgery had been delayed for medical reasons were excluded. We divided the patients into four groups depending on the delay to surgery. Analysis of pre- and postoperative characteristics showed the groups to be similar. Mortality in the four groups was not significantly different but morbidity was increased by delay, particularly with regard to the incidence of pressure sores.

Analysis of Variance↗

Poor results following internal fixation of displaced subcapital femoral fractures: complacency in fracture reduction.

The results following internal fixation of displaced subcapital femoral fractures are poorer than for undisplaced fractures and are determined by both the quality of the initial reduction and the accuracy of implant placement. In a series of 26 consecutive displaced fractures internally fixed with Richards hip pins, satisfactory reduction was achieved in only 15 hips. Accurate reduction is a prerequisite for correct screw placement and occurred in only 4 of the 11 poorly aligned fractures, as opposed to 11 of the 15 well reduced ones. A total of 10 hips required a further surgical procedure as the result of complications. These results highlight the importance of accurate fracture reduction in facilitating implant placement as well as the importance of good surgical technique rather than reliance purely upon the implant. These already common fractures are assuming increasing socioeconomic importance as the elderly population grows, and successful management is vital for both the individual patient and future demands on the health service.

Adult↗

[Morbidity and mortality of osteoporotic proximal femoral fracture after one year follow-up].

BACKGROUND: The aim of the present study was to follow for a year all the osteoporotic proximal femoral fractures that happened in the island of Gran Canaria during 1990 and to analyze: a) mortality; b) the degree of functional capacity; c) their destination after being attended from the fracture. METHODS: Personal interviews were performed in almost every patient (68%), either directly to them or the relatives who were at their care (23.5%), after excluding those patients who died during the acute phase (7.6%) a year after the fracture. Two patients were missed (0.9%). We had the collaboration of every public and private center in the island. 209 patients (154 women and 55 men) were interviewed. Age mean of the patients was 77.1 +/- 10.9 years. The degree of functional capacity was determined by Karnofsky scale. RESULTS: Mortality within the acute phase was 7.6%, rising to 20.8% 6 months later and to 30.7% after a year. There was an important disability in 30.7% of the remainder living patients. In the postsurgical period, 18% of the patients were transferred to a center for chronic care and 25% to a rehabilitation center. Although 48.9% of the patients are discharged to their homes from the hospital, surprisingly, when they die, only 15% do so in their homes, while 59% of the patients die in a center for chronic care. CONCLUSIONS: Osteoporotic proximal femoral fracture produces an important mortality within the first year after fracture, and also an important deterioration of functional capacity. Most of the patients are admitted later on and die in a center for chronic care.

Aged↗

Femoral fracture repair complicated by vascular injury in a foal.

A comminuted, mid-diaphyseal femoral fracture was diagnosed radiographically in a 4-month-old Quarter Horse colt. Disruption of the distal blood supply was suspected, as evidenced by coolness and diminished pulses of the distal portion of the limb. The fracture was repaired by compression plating but the foal's condition continued to deteriorate. A femoral arteriogram of the affected limb was obtained. Positive contrast agent was visible only as far as the mid-shaft of the femur. The foal was euthanatized and the postmortem examination revealed a transected popliteal artery accounting for ischemic necrosis of the distal limb.

Animals↗

Gamma nail vs compression screw for trochanteric femoral fractures. 15 reoperations in a prospective, randomized study of 378 patients.

A total of 378 trochanteric and subtrochanteric femoral fractures were randomized to treatment with Gamma nail (177) or Hip Compression Screw (HCS) (201). After a median follow-up time of 17 (10-27) months, 15 patients needed reoperations; 13 had been treated with Gamma nail and 2 with HCS. 10 patients, all treated with Gamma nail, were reoperated because of a femoral shaft fracture. 5 of these fractures occurred 8 (4-10) days postoperatively and were related to intraoperative complications. The other 5 shaft fractures occurred a median of 2 (1-3) months postoperatively after falls, and may be related to stress concentration at the tip of the solid nail. The lag screw cut out or penetrated the femoral head in 5 patients, 3 of them treated with Gamma nail and 2 with HCS.

Aged↗

Torsion in femoral fractures in childhood. A longitudinal investigation.

A photogrammetric method developed for measurement of femoral neck anteversion was used to evaluate the torsion in 28 femoral fractures sustained in childhood and treated conservatively. Spontaneous correction of the initial torsion of 10 degrees to 30 degrees to less than 10 degrees was the rule in a growing femoral bone within 5 to 10 years after trauma.

Adolescent↗

Correction by growth of rotational deformity after femoral fracture in children.

Fourteen children with femoral shaft fractures were studied for 10 years after fracture or until growth plate closure, using repeated anteversion measurements. A mean anteversion difference of 9.6 degrees between the fractured and intact sides after fracture consolidation decreased to 5.6 degrees (p less than 0.01), indicating that children have a considerable ability to correct a rotational deformity by growth, especially during the first years after fracture. It was also found that tibial pin traction results in a greater rotational deformity than does bilateral Bryant traction.

Adolescent↗

An externally fixed femoral fracture model for mice.

Transgenic and knockout mouse models can be used to help understand the molecular mechanisms of fracture repair. This study examines the feasibility of applying an external fixator to the mouse femur as one model for studying fracture repair. The external fixator consisted of two aluminum blocks connected by two rods. Four pins are used to connect the blocks to the bone. Mechanical characterization of the fixators was carried out prior to their use. Sixty-two wild type mice with bilateral femoral fractures were created using an open technique and fixed using the fixator. The progress of fracture healing was monitored radiologically before sacrifice and by mechanical testing and histology after sacrifice. Initially four mice died intraoperatively from excessive blood loss, the intraoperative mortality was subsequently reduced by subcutaneous saline infusion. The bone healed between 14 and 21 days after fracture and remodeled by 60 days. Both radiological and mechanical assessments showed a steady progression of bone healing. Histology demonstrated callus and endochondral bone formation. This study demonstrated that it is possible to create a mouse femoral fracture model stabilized by external fixation and will provide an additional model to the understanding of fracture healing in transgenic and knockout mice.

Animals↗

Pathological femoral fracture due to rhabdomyosarcoma in a cat.

An eight-year-old neutered male domestic shorthaired cat was presented with non-weightbearing lameness of the right hindlimb. On radiography, a pathological, metaphyseal femoral fracture was apparent, with areas of bony lysis directly surrounding the fracture site. The cat underwent amputation of the limb. Histopathological examination revealed the presence of a tumour of mesenchymal cells with cytoplasm-containing vacuoles which stained positive with the periodic acid-schiff reaction, indicative of glycogen granules that may be found in rhabdomyosarcoma cells. In addition, the tumour cells stained positive for vimentin and desmin on immunohistochemical examination, thus confirming the diagnosis of rhabdomyosarcoma. In spite of the radical surgery performed, the cat was euthanased due to a recurrence at the amputation site four and a half months later.

Amputation, Surgical↗

[Malignant fibrous histiocytoma of bone 20 years after femoral fracture treated by plate-screw fixation: analysis of corrosion products and their role in malignancy].

We report a case of malignant fibrous histiocytoma of the bone that developed 20 years after a femoral fracture treated by plate-screw fixation. Similar cases reported over the past fifteen years in the literature suggest the possible mechanisms of sarcomatous degeneration. The possible carcinogenic effect of corrosion products is emphasized. Dispersion energy spectrometry of intracellular particles on the periphery and at the center of the tumor demonstrated the presence of chromium, iron and nickel at different concentrations. The association with other elements clearly demonstrates that the corrosion products were metabolized. The presence of metallic components in tumoral cells suggests a possible relationship between metallic implants and malignancy. These observations emphasize the importance of creating a national, or even international, registry of malignant tumors that develop in contact with metallic implants in order to search for a possible cause and effect relationship.

Adult↗

Biomechanical aspects of femoral fractures in automobile accidents.

A medical and engineering study was made of 1074 car accidents involving 2520 vehicle occupants. The injuries they sustained were correlated with details of the crash and with contact points inside the cars. Where possible the forces which were generated in the crash were estimated and related to the injuries. In all, 39 car occupants suffered femoral shaft fracture, with an incidence of 1.7% and 0.8% for front and rear seat occupants respectively. Of these, 31 had associated injuries to other regions of the body; these were the cause of 13 of the 14 deaths in this group. Associated injuries were more severe in car occupants who were not wearing seat belts but the incidence of femoral fracture was not significantly different. The mean velocity change (delta-V) causing femoral fracture was 26 mph (42 km/h) and there was a higher incidence of femoral shaft fracture when delta-V was over 30 mph. Estimates of forces needed to cause fracture were higher than those found in cadaver studies. The time to union of femoral fractures did not correlate with the severity of the crash but was longer (mean 19 weeks) than the average for other femoral fractures.

Accidents, Traffic↗

Distal femoral fractures. Comparison of open and closed methods of treatment.

Ninety-eight distal femoral fractures were analyzed to compare open and closed treatment methods. Four radiographic groups were identified. Patients treated by open methods spent less time in the hospital, returned to prefracture activity sooner, had better functional results, and had a lower incidence of nonunions and complications. Thirty-eight of 47 fractures treated by open methods had good functional results. Only 18 of 51 fractures treated by closed methods had good functional results. Simple nondisplaced fractures were noted to have good results when treated by closed methods. Fractures of the distal femur, except the most simple cases, are best managed by open treatment methods.

Activities of Daily Living↗