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Dose reduction in xeroradiography of the breast.

In a study of the effects of beam filtration on the entrance exposures encountered in xeroradiography of the breast, it was found that increasing the total filtration to 3.2 mm of aluminum reduced entrance exposures by a factor of three compared to the xeroradiographic techniques without added filtration. Changes in the processing parameters were found to restore much of the lost contrast observed when filtration was increased, resulting in clinically acceptable mammograms at reduced entrance exposures.

Female↗

Excessive use of inhaled salbutamol: the potential benefits of dose-reduction. A case report.

Inhaled, short-acting, beta-agonist medications are widely used in the treatment of asthma. It is recommended in current asthma management guidelines that these medications should only be used "as required" for relief of asthma symptoms. Despite this, there are still a number of asthmatic patients who are using excessive amounts. In occasional patients this may be detrimental to the control of asthma. We report the case of a 43-year-old, steroid-dependent asthmatic, with unstable asthma, using salbutamol up to 30 times a day. Following reduction of her beta-agonist use she had a dramatic improvement in her asthma control and was able to successfully stop her oral steroids.

Administration, Inhalation↗

[Radiochemotherapy of head and neck cancers: dose reduction through the combination of cisplatin, bleomycin and tegafur].

Twenty-four cases of squamous cell carcinomas of the larynx and maxillary sinus were irradiated with or without cisplatin during a period from April 1973 through March 1984. Both bleomycin in oil and tegafur were administered irrespective of cisplatin. Therapeutic effectiveness was critically evaluated by means of serial biopsy and/or surgery. Radiotherapy alone could not bring about negative conversion of the biopsies, but ultimate negative conversion was observed in 18 out of the 24 cases when chemotherapeutics were appropriately combined. The five positives underwent surgery. In the cases of maxillary cancer, mixed infections appeared to interfere with the curative effectiveness of the radiochemotherapy. A resulting dosage reduction of 15Gy was observed in radiotherapy for negative conversion and one of 10mg for bleomycin as a result of incorporation of cisplatin.

Adult↗