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At least 379 records · Page 21Linked to original sources
PubMed2004

[The reason and treatment of portal vein thrombosis in patients with portal hypertension postoperation].

OBJECTIVE: To investigate reason and the management of portal vein thrombosis in patients with portal hypertension postoperatively. METHODS: 329 patients with portal hypertension in liver cirrhosis who had splenectomy was reviewed from 1992 to 2001. In whom 43 (13.1%) patients with portal vein thrombosis postoperative were analyzed. RESULTS: In these patients, except 1 died for portal vein phlebitis, all patients were recovered. There are 138 patients who underwent splenectomy or splenectomy and devascularization, 26 (18.8%) of them had thrombosis. 191 patients underwent splenectomy and portacaval or portasplenic shut, 17 (8.9%) of them had thrombosis. The data of these two groups have significant difference (chi(2) = 8.44, P < 0.01). CONCLUSIONS: Thrombocytosis postsplenectomy as well as the changes of portal hemodynamics is the main reason of portal vein thrombosis. Portal vein thrombosis is also in association with the operative ways. Operation standardization, dynamic examining platelet count, routine color ultrasonography examining and early anticoagulation therapy are the effective methods in preventing and managing portal thrombosis postoperation for portal hypertension.

Adult↗
PubMed1989

[The color of drugs: a preliminary survey].

An inquiry has been conducted on the colours considered more suitable for four kinds of drugs. In general, while light colours are indicated for antianxiety and sleep-inducing drugs, bright colours are indicated for antidepressant and tonics.

Adult↗
PubMed1989

[Two-color analysis of peripheral blood lymphocytes in patients with malignant tumours after low dose half (or total) body irradiation--a pilot study].

The mechanism of anti-tumour effect of low dose total body irradiation applied for non-Hodgkin's lymphoma is still unknown. Two-color analyses of peripheral blood lymphocytes from ten patients with non-Hodgkin's lymphoma or advanced cancer who received low dose total body irradiation (TBI) or half body irradiation (HBI), were performed to be a help to reveal the mechanism. The results of these analyses indicated that the proportion of helper T lymphocytes, helper-inducer T lymphocytes and cytotoxic T lymphocytes increased during TBI or HBI. On the other hand, the proportion of suppressor-inducer T lymphocytes and suppressor T lymphocytes seemed to decrease slightly. The extent of bone marrow suppression of twice-a-week TBI or HBI was clinically no problem, but in the case of thrice-a-week TBI, prolonged bone marrow suppression might occur. In the case of half body irradiated five patients who were administered with lentinan for several weeks to several months before TBI or HBI, the pre-HBI value of the proportion of cytotoxic T lymphocyte fraction was found to be high, and the increment of the proportion of helper T lymphocyte was larger than that of non-lentinan treated cases.

Aged↗
PubMed1988

A potential method for local drug and dye delivery in the ocular vasculature.

We propose a new drug and dye delivery system that would allow repeated release of substances in the ocular vasculature by an externally controlled mechanism. The substances are encapsulated in heat-sensitive liposomes, which are lysed by locally applying a heat pulse produced by an argon laser. The system was tested by investigating the release of carboxyfluorescein encapsulated in the liposomes. The liposome suspension was incubated at 37 degrees or 38.5 degrees C and irradiated at different powers and pulse durations. The amount of dye released was monitored by fluorophotometry and compared with the concentration obtained when the liposomes were lysed at their transition temperature of 41 degrees C. The results showed that 85% of the encapsulated substance can be released. Moreover, a dramatic contrast was observed between the fluorescence before and after the lysis. Presently the energy density is higher than but close to the maximal permissible exposure for humans. The release mechanism with the short laser pulse appeared to be similar to that present when liposomes were heated slowly.

Coloring Agents↗