Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “CERVIX EROSION”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 379 records · Page 21Linked to original sources
PubMed1976

Morphologic studies on the non-cancerous cervix in Jamaicans at different ages.

A morphologic investigation on 100 cervices removed at autopsy from negro Jamaican women at different ages showed that columnar epithelium was frequently located on the portio vaginalis at all ages. The absence of this phenomenon in some fetal cervices supports the hypothesis of embryologic displacement rather than stimulation by maternal estrogens. Squamous metaplasia was common at all ages, even in the fetus; it showed little relationship to chronic inflammation, but the high frequency in post-pubertal cases (80%) could have some relationship to the high incidence of cervical cancer in Jamaica. Chronic inflammation was not observed in the fetal cervix but occurred in most infants in whom it was attributed to congenital "erosion". However, the cervices of children revealed a marked discrepancy between the presence of "erosion" and the degree and frequency of chronic inflammation (83%). This change is unexplained and requires further study.

Adolescent↗
PubMed1987

Ulcer of the trigone: a late complication of cervical cerclage.

Since the introduction of cervical cerclage for management of the incompetent cervix, few late complications of the procedure have been reported. We report a late complication of cervical cerclage manifested as a trigonal ulcer. Trigonal erosion by the knot of a mersilene ligature that had been placed around the cervix 22 years previously caused the ulcer. Endoscopic removal of the offending ligature allowed complete healing.

Female↗
PubMed2003

[Analysis of physiologic and abnormal pictures of uterine cervix by means of infrared thermography].

RATIONALE FOR THE STUDY: Diagnosis of the uterine cervix lesions remains a key element of the women's health care especially in the context of the cervical carcinoma prophylaxis. The infrared mapping constitutes a new generation biophysical diagnostic method of potential application in medicine. OBJECTIVE: The study was planned to analyze uterine cervix thermograms in both physiology and pathology of this organ. An attempt was made to establish the standard thermographic pattern of the portion. MATERIAL AND METHODS: The study population consisted of 51 women aged from 20 do 70 years. In total, 109 thermographic patterns were analyzed by the computer processing of the thermovision data. In order to establish a physiologic standard, 14 thermograms of the normal cervix were analyzed in detail. Furthermore, thermograms of such cervical lesions as endocervical polyp (3 patients), erosion (PAP II) (11 cases), CIN I-III (9 patients) and invasive cancer (6 patients) were studied. The diagnosis was based on clinical, cytologic and colposcopic criteria as well as on the pathology report. The infrared camera AGEMA AGA-880 and the specialized software was used. The measurements were done in a standardized climatic environment. RESULTS: Comparisons between the studied groups revealed significant differences between invasive cervical cancer and benign lesions or healthy cervix. Significant were also differences in mean temperature and highest temperature for all the studied groups. The difference in mean whole portion temperature between the normal cervix and invasive planoepithelial cancer amounted to 1.4 degrees C while in comparison to other lesions it did not exceed 0.5 degree C. Statistical analysis of the averaged profiles of cervical temperatures has also shown significant differences between invasive cancer and the remaining groups--by 1.5 degrees C in average. Strong interrelationships (p < 0.001) were found among the single results of thermography measurements within all the groups. The thermographic profiles of all 14 thermograms of normal portion did not exceed the two standard deviations range of the established standard with the mean temperature of 36.56 degrees +/- 0.56 degree C. CONCLUSIONS: 1. The established thermographic mapping patterns of the normal cervix may form a basis for the future evaluation of the diagnostic application of computer thermography in gynecology. 2. Statistically significant differences were found in thermographic profiles of the portion between the normal cervix and such cervical lesions as endocervical polyp, erosion (PAP II), CIN and invasive cancer. 3. Invasive cervical cancer reveals thermographic pattern of relatively high specificity within the analyzed cervical lesions.

Adult↗
PubMed2004

Telomere attrition predominantly occurs in precursor lesions during in vivo carcinogenic process of the uterine cervix.

Although human papillomavirus (HPV) has been defined as the pathogen for cervical carcinomas, molecular events underlying the oncogenic process are unclear. As telomere dysfunction-mediated chromosomal instability and telomerase activation have been suggested as key events in carcinogenesis, we dissected the dynamic changes in telomere length, checkpoint response, and temporal profile of telomerase expression during the evolution from precursor lesions (cervical intraepithelial neoplasia, CINs) to invasive cancers of the uterine cervix in sequential samples from 16 patients. Telomeres were significantly shortened in all CIN samples and no further substantial attritions occurred in most cases with the acquisition of malignant phenotype. Very short telomeres were coupled with constitutive activation of the DNA damage response pathway (Chk2 phosphorylation) and increased cellular proliferation in those cervical specimens. Telomerase reverse transcriptase (hTERT) expression was preferably induced at advanced CINs or invasive cancers. The present finding demonstrates that excessive telomere shortening predominantly occurs in the early carcinogenesis of the uterine cervix largely prior to telomerase activation. Widespread over-erosion of telomeres or telomere dysfunction in very early stages of cervical tumorigenesis might fuel transformation processes by driving chromosomal instability.

DNA Damage↗
PubMed1993

[The clinico-morphological and cytological characteristics of the ecto- and endocervix with the use of the oral contraceptive triregol].

Cervix uteri status was examined in 55 young nulliparous women in the course of triphasic oral contraception. The status of the cervix uteri was assessed on the basis of clinical, colposcopic, cytologic, and morphofunctional examinations. Triphase oral contraception with triregol was found conducive to the formation of squamous-cell metaplasia in ectopic sites, this promoting epithelialization of the cervix uteri.

Adolescent↗
PubMed1998

[Epidermolysis bullosa acquisita and metastatic cancer of the uterine cervix].

INTRODUCTION: Epidermolysis bullosa acquisita may be associated to a systemic or malignant disease. Here, we report a case of epidermolysis bullosa acquisita associated with a carcinoma of the cervix. CASE REPORT: A 44-year-old woman presented inflammatory, bullous and erosive mucocutaneous lesions. Investigations lead to the diagnosis of epidermolysis bullosa acquisita and revealed pelvic metastases originating from a poorly differentiated carcinoma. The cutaneous lesions completely regressed after the treatment of the tumor but reappeared with tumoral relapse. DISCUSSION: This is the first report of an association of epidermolysis bullosa acquisita and carcinoma of the cervix. The clinical course of these two entities suggests that the EBA in this case may be paraneoplastic.

Adult↗
PubMed2002

Role of socio-economic factors and cytology in cervical erosion in reproductive age group women.

A cross-sectional study involving 357 females in the reproductive age group (15-44) was conducted in an urban community of Nagpur with the objective of studying the role of socio-economic factors & cytology in cervical erosion. Cervical erosion was detected in 82 (22.96%) females. Out of these mild dysplasia was seen in 9.75% females & moderate dysplasia in 2.43% females. High percentages of inflammatory smears i.e. (75.68%) were obtained in women with cervical erosion. Cervical erosion was more common in illiterate & women with low literacy status as compared to women with higher education. Majority of cases of cervical erosion (75.6%) were detected in women with high parity. A statistically significant association was found between lower socio-economic status, early age at marriage & ocurrence of cervical erosion (p<0.001 & p<0.01 respectively). The study concludes that socio-economic factors such as illiteracy and low literacy status, lower socio-economic status, early age at marriage and high parity are contributory for the occurrence of cervical erosion and regular cytological screening by Pap smear will help in early detection of carcinoma cervix and thereby reduce the morbidity and mortality caused by the same.

Adult↗