Bladder exstrophy and exomphalos in successive pregnancies.
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During the period from 1961-1995 the incidence of extrophy of the urinary bladder was investigated on the territory of the Czech Republic. From a consecutive series of 5,137,907 infants born in the Czech Republic in 1961-1995 65 cases of this defect were diagnosed. The mean incidence of extrophy of the urinary bladder in born children during the investigation period was 0.14 per 10,000 liveborn. Nationwide data on the prenatal diagnosis of this defect during the investigation period are not available so far.
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We present a case of vesical extrophy complicated by an adenocarcinoma in a 35-year old patient. It is this type of neoformation which most frequently affects the extrophic bladder and which, contrary to what has happened in most of the cases published, quickly presented bone and skin metastases.