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Anthropophilic mosquitoes at Richards Bay, Natal, and arbovirus antibodies in human residents.

A survey at Richards Bay, the site of a new international harbour on the east coast of South Africa, revealed the presence of 11 anthropophilic mosquito species. These are discussed in relation to their known medical importance and to a complementary survey of arbovirus antibodies among residents of the area. Mansonia uniformis was by far the most abundant man-biting mosquito. Antibodies against Germiston, Banzi and Rift Valley Fever viruses were the three most commonly encountered, being detected in 29.7, 12.2 and 8.7% of residents respectively. This new knowledge updates the distribution and prevalence of arbovirus antibodies in man in northern Natal.

Adult↗

Arboviruses recovered from sentinel livestock in northern Australia.

Over 700 arboviruses were recovered between 1981 and 1987 from the blood of sentinel livestock near Darwin. Twenty-three isolates were made from sheep, goats, swamp buffalo (Bubalus bubalis) and horses, and the remainder were from cattle. The isolates have been typed as 27 separate viruses belonging to the bluetongue, epizootic haemorrhagic disease, Palyam, Simbu, bovine ephemeral fever, Tibrogargan and alphavirus groups. Ten of these viruses have not been isolated elsewhere in Australia and four have been isolated only in Darwin. Considerable annual variations in virus activity and in the durations of detectable viraemia were observed.

Animals↗

Effects of altitude, distance and waves of movement on the dispersal in Australia of the arbovirus vector, Culicoides brevitarsis Kieffer (Diptera: Ceratopogonidae).

The dispersal of the biting midge and arbovirus vector Culicoides brevitarsis in the Bellinger, Macleay and Hastings river valleys and up the escarpment of the great dividing range (GDR) of mid-northern coastal New South Wales, Australia, from 1995 to 2003 was studied. The midge moved up these valleys from the endemic coastal plain in at least two waves between October and May, and both waves were modelled. Dispersal time can be explained by direct distance from the coast and the altitude of the sites. Dispersal times due to distance were similar at 18.2 +/- 2.2 (S.D.) and 15.9 +/- 2.6 weeks per 100 km for first- and second-occurrences at fixed altitude. Time of the first wave was extended 0.48 +/- 0.22 weeks for every 100-m rise in altitude and the second by 1.14 +/- 0.24 weeks for every 100-m rise for a set distance. Although C. brevitarsis can move up the escarpment of the GDR (and possibly transmit virus), vector dispersal, survival and establishment at and beyond the top of the range are limited. A third model showed that previously described slower movement of C. brevitarsis up the more-southerly Hunter valley relative to movements down the coastal plain also was related to increasing altitude.

Altitude↗

Neuropathology of S. Paulo south coast epidemic encephalitis (Rocio flavivurus).

The neuropathology of 8 cases of S. Paulo south coast epidemic encephalitis (Rocio flavivirus), a new arbo B virus encephalitis, is described. The topographic pattern of the lesions appears to be almost specific. The gray matter is predominantly affected. Interstitial mononuclear infiltration, microglial proliferation and perivascular lymphocytic cuffing were seen. Neuronophagia was seldom seen except during the acute phases of the disease. Throughout the neuraxis, the gray matter was affected to a greater degree than white matter. The more damaged structures, in descending order, were as follows: thalamus, dentate nucleus, substantia inominata, brain stem, spinal cord and basal nuclei. Most of the cases exhibited thalamic inflammatory necrosis. Electron microscopy disclosed in one case virus-like particles, resembling those described in other arbo B viruses in the cytoplasm of thalamic neurons. In this case, virus was isolated from the brain and an immunofluorescence test also showed antigenic material in the thalamic neurons.

Adolescent↗