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Abnormal responses of electronic pocket dosimeters caused by high frequency electromagnetic fields emitted from digital cellular telephones.

High frequency electromagnetic fields emitted from digital cellular telephones (cell phones) occasionally cause abnormally high and erroneous indicated dose readings on electronic pocket dosimeters (EPDs). Electric field strength distribution around a cell phone transmitting 1.5 GHz band with a maximum power of 0.8 W was analyzed by using an isotropic probe with tri-axial dipole antennas. Five types of EPDs were exposed to the fields for 50 s under configurations relative to the cell phone. The electric field distribution expanded around the phone's antenna and had a maximum electric field strength of 36.5 +/- 0.3 V m(-1). The cell phone gave rise to erroneous indicated dose readings on four out of five EPDs. The maximum value of erroneous indicated dosage for 50 s reached 1,283 microSv, which was about 2.6% of the annual effective dose limit of 50 mSv. The electromagnetic susceptibility of the EPDs was higher in the sections where the semiconductor detectors or electric circuit boards were located. The distance required to prevent electromagnetic interference differed for each EPD and ranged from 2.0 to 21.0 cm from the cell phone. The electric and magnetic field immunity levels of the EPDs varied from 9.2 V m(-1) to greater than 37.6 V m(-1), and from 0.03 A m(-1) to greater than 0.51 A m(-1). The EPDs displayed erroneous dose readings during exposure but recovered their normal performance after the cell phone ceased transmitting. The electromagnetic immunity levels of the EPDs were either equal to or greater than the IEC-standard. The immunity levels should be enhanced greater than the IEC-standard from the standpoint of radiation protection. The simplest and most reliable measure to prevent potential malfunction is to prohibit the radiation workers from carrying cell phones to their workplace.

Cell Phone↗

[Experimental study on the disinfection of wastewater by swept pulsed electromagnetic field].

In this paper, an applicable swept pulsed equipment was developed to treat the domestic wastewater and the effect of swept pulsed electromagnetic field on disinfection was studied. It was found that the effect was obvious and the disinfection performance of electromagnetic field was increased with the increasing of the pH, the temperature, the treatment time and the bactericidal concentration. The experimental results showed that the amounts of total bacterium and coliform per milliliter were decreased from 7.2 x 10(6) to 2.2 x 10(4) and from 9.2 x 10(5) to 3.5 x 10(4) respectively after the treatment period of 4 h when the temperature was 25 degrees C and pH 9.0. Corresponding, the removal efficiency of total bacterium were 99.7% and 96.2%.

Bacteria↗

Effect of pulsed electromagnetic fields on calcium tissue changes in focal ischaemia.

The effect of a pulsed electromagnetic field (PEMF) (parameters: 27.1 MHz, 585 W peak power, and 65 microseconds pulses, 400 times per second) on rats undergoing middle cerebral artery occlusion (MCAo) was investigated. Four groups of eight rats each underwent microsurgical MCAo. Two groups were treated with a PEMF generator for 2 h following the onset of ischemia and were sacrificed at 4 and 24 h following the MCAo respectively. The other two groups were also sacrificed at the same time intervals. Regional brain sodium, potassium, and calcium tissue contents were determined by atomic spectrophotometry. As distinct from results found in spinal cord contusion, no significant difference between the PEMF-treated groups and the non-treatment groups was found. PEMF treatment did not alter the 300% rise in calcium tissue dry weight content observed at 24 h following MCAo in the infarcted tissue. Regional brain water content was determined by the dry weight method. A regionally inconsistent reduction in brain water content was noted in the PEMF-treated rats.

Animals↗

Pulsed electromagnetic fields alter phenotypic expression in chondroblasts in tissue culture.

We hypothesize that pulsed electromagnetic fields (PEMF) alter phenotypic expression of chondroblasts by promoting the production of alkaline phosphatase (AP) and altering the structure of proteoglycans. Chondroblasts from the hypertrophic zone of tibial epiphyses (HC), sternum (SC), and skin fibroblasts (F) were cultured from 16 day chick embryos. Cultures were randomly designated control (C) or experimental (E). E received PEMF for 24 h in a 6 h on, 6 h rest sequence. The controls were in the same incubator shielded by Mu metal. Assays for AP activity were performed and normalized to protein content. Proteoglycan synthesis assay involved labeling with 35S fractionating in a 5% to 20% surcrose gradient determining total protein and chondroitin sulfate content. PEMF showed no change of AP activity on F. A high AP basal activity was found in HC, but was not increased above the control. PEMF increased AP in the SC samples (E/C ratio). The sucrose gradient data showed a shift in peaks for SC only altering the ratio of carbohydrate to protein for the SC. Analysis of carbohydrate and protein indicated that the effect was decreased synthesis or degradation of protein. We conclude that PEMF alters the phenotypic expression of sternal chondroblasts in our in vitro system.

Alkaline Phosphatase↗

Enhanced deposition of radon daughter nuclei in the vicinity of power frequency electromagnetic fields.

We report the attraction of radon daughter nuclei in normal domestic room air to everyday sources of power frequency electromagnetic fields. TASTRAK plastic track detectors were used to measure alpha-emission from the radon (222Rn) daughters 218Po and 214Po close to 50-Hz mains frequency power cables and domestic appliance leads. We observed that wires carrying mains frequency potential attract radon daughter nuclei in a manner visually similar to the attraction of iron filings to a magnet. Increased deposition of up to a factor of 18 was observed. Further experiments designed to simulate the effect of overhead power lines at ground level showed large scale variations in local plateout and airborne concentration of radon daughters. The effects appear to be due to interactions of the electric component of the EM-field with both the ultrafine and attached fraction of radon daughter aerosols. Three mechanisms have been examined. First, aerosols instantaneously polarize in sympathy with the electric component of an applied mains frequency EM-field and as a result may migrate up strong E-field gradients. This effect is however quite weak and may only affect larger aerosols in strong field gradients. Second, charged aerosols oscillate in a 50-Hz field and in the case of the ultrafine fraction this may lead to significantly increased plateout. Third, there is the possibility that oscillation of charged aerosols induces fluctuations in the magnitude of the instantaneous charges carried and this results in a diffusive-like motion along the field lines. The effect on dose to body organs is considered. Enhanced plateout on the skin is likely, increasing the dose to the basal layer. The dose to internal organs is governed initially by inhalation and lung deposition of radon daughters. Therefore increased local concentration in room air could lead to increased dose by inhalation. E-fields are heavily attenuated by the human body and body values in tissue of no more than 10(-4) of the external field strength have been suggested. Nevertheless calculations suggest that under exposure to strong external fields this may still be sufficient to alter the deposition pattern of the charged component of the ultrafine fraction in the bronchial region. In contrast it is unlikely that internal electric fields could significantly affect the attached radon daughters. In this context the lack of measurements of residual E-fields in the cavities of the mouth, pharyngeal and bronchial regions is of considerable importance and should be addressed. We believe that the observations may have implications for the apparent enigma that there is no persuasive biological evidence to show that power frequency electromagnetic fields can influence any of the accepted stages in carcinogenesis. On the contrary, the observations show that EM-fields can concentrate in their vicinity a cocktail of radon daughter nuclei, a known carcinogen, and presumably other potentially harmful agents.

Aerosols↗

Elevated risk of Alzheimer's disease among workers with likely electromagnetic field exposure.

We conducted a case-control study of the possible association of occupations with likely exposure to electromagnetic fields and Alzheimer's disease (AD) with patients from the Alzheimer Disease Treatment and Diagnostic Center, Rancho Los Amigos Medical Center, Downey, CA. Patients with definite or probable AD were the case subjects (86 male, 240 female). Patients with cognitive impairment/dementia other than vascular dementia were control subjects (76 male, 76 female). The study was limited to patients who were at least age 65 at the time of their first examination at Rancho Los Amigos. The odds ratio for both sexes combined was adjusted for sex, education, and age at onset. The odds ratio for males was adjusted only for age at onset, and the odds ratio for females was adjusted for both education and age at onset. The adjusted odds ratio for both sexes was 3.93 (p = 0.006), 95% CI = (1.5 to 10.6). For males the adjusted odds ratio was 4.90 (p = 0.01), 95% CI = (1.3 to 7.9), and for females the adjusted odds ratio was 3.40 (p = 0.10), 95% CI = (0.8 to 16.0). These results are consistent with previous findings regarding the hypothesis that electromagnetic field exposure is etiologically associated with the occurrence of AD.

Aged↗

Adult glioma in relation to residential power frequency electromagnetic field exposures in the San Francisco Bay area.

In a population-based study, we examined residential power frequency electromagnetic field exposures for 492 adults newly diagnosed with histologically confirmed glioma between August 1, 1991 and April 30, 1994, in the San Francisco Bay area and 462 controls, obtained through random-digit dialing frequency, matched to cases for age, gender, and race. Residential exposure assessment consisted of spot measures with EMDEX (Enertech Consultants, Campbell, CA) meters and wire codes based on characterization and location of nearby power lines. We considered the index residence at the time of the case's diagnosis or the control's interview and all other California residences of each subject for 7 years before study entry. We obtained wire codes for eligible residences of 76% and for index residences of 99% of subjects. Using the Kaune-Savitz wire code classification, the relative risk for longest held residences coded as "high" compared with "low" was 0.9 [95% confidence interval (CI) = 0.7-1.3], while relative risk and 95% CIs for front door spot measures of 1.01-2 milligauss, 2.01-3 milligauss, and higher than 3 milligauss compared with < or =1 milligauss were 1.0 (0.7-1.4), 0.6 (0.3-1.1), and 1.7 (0.8-3.6). Adjustment for age, gender, race, and whether the subject owned the residence did not meaningfully alter these findings, nor did comparisons using index or highest coded residence. Because of potential exposure misclassification and the unknown pertinent exposure period, these data cannot provide strong support against, but clearly do not support an association between, adult glioma and residential power frequency electromagnetic field exposures.

Adult↗

Osteogenesis by pulsing electromagnetic fields (PEMFs): optimum stimulation setting.

The optimum setting for electromagnetic stimulation was examined by histologically assessing the degree of osteogenesis at different settings of electromagnetic stimulation, and comparing alkaline phosphatase (ALP) activity in the bone marrow. For this experiment, an electromagnetic field generator manufactured by the Institute of Physical and Chemical Research was used. The intensity of the magnetic field was set at eight levels; 0.1, 0.2, 0.4, 1, 2, 4, 6 and 8 gauss (G). The frequencies used were 5, 10, 20, 50, 100 and 200 Hz. Pulse durations were 6, 12, 25, 50 and 100 micro sec. Significant ALP elevation and osteogenesis were observed at magnetic field intensities of 0.4, 1, and 2G. ALP activity did not differ between different frequencies. ALP activity at pulse durations of 25 and 50 micro sec were significantly higher than at the other pulse durations. The effect of electromagnetic stimulation on osteogenesis greatly depends on the intensity and pulse duration of the stimulation.

Alkaline Phosphatase↗

Electromagnetic field of mobile phones affects visual event related potential in patients with narcolepsy.

The effects of the mobile phone (MP) electromagnetic fields on electroencephalography (EEG) and event-related potentials (ERP) were examined. With regard to the reported effects of MP on sleep, 22 patients with narcolepsy-cataplexy were exposed or sham exposed for 45 min to the MP (900 MHz, specific absorption rate 0.06 W/kg) placed close to the right ear in a double blind study. There were no changes of the EEG recorded after the MP exposure. A subgroup of 17 patients was studied on visual ERP recorded during the MP exposure. Using an adapted "odd-ball" paradigm, each patient was instructed to strike a key whenever rare target stimuli were presented. There were three variants of target stimuli (horizontal stripes in (i) left, (ii) right hemifields or (iii) whole field of the screen). The exposure enhanced the positivity of the ERP endogenous complex solely in response to target stimuli in the right hemifield of the screen (P < 0.01). The reaction time was shortened by 20 ms in response to all target stimuli (P < 0.05). In conclusion, the electromagnetic field of MP may suppress the excessive sleepiness and improve performance while solving a monotonous cognitive task requiring sustained attention and vigilance.

Brain Mapping↗

[Effects of extremely low frequency electromagnetic fields on apoptosis and cell cycle of mouse brain and liver cells].

OBJECTIVE: To study the effects of extremely low frequency electromagnetic fields (ELF EMFs) on apoptosis and cell cycle of mouse brain and liver cells. METHODS: Mice were exposed to 50 Hz, 0.2 mT or 6.0 mT electromagnetic fields for 2 weeks. TUNEL and flow cytometric methods were used to analyze apoptosis and cell cycle of brain and liver cells. RESULTS: After exposure to 0.2 mT and 6.0 mT ELF EMFs for 2 weeks, apoptosis rates of brain cells [(5.60 +/- 1.47)% and (4.73 +/- 0.48)% respectively] were higher than that of control [(2.90 +/- 0.75)%], and apoptosis rates of liver cells [(4.19 +/- 2.08)% and (3.38 +/- 0.65)% respectively] were higher than that of control [(1.84 +/- 0.76)%]. G0/G1 cell percentage of brain cells [(80.21 +/- 1.68)% and (79.54 +/- 0.56)% respectively] were higher than that of control [(76.85 +/- 0.83)%], and those of liver cells [(79.42 +/- 1.80)% and (80.47 +/- 1.79)% respectively] were higher than that of control [(73.36 +/- 3.10)%]. The above differences were all statistically significant as P < 0.05. At the same time S and G2 + M cell percentage of brain and liver cells were significantly decreased. CONCLUSION: Exposure to 50 Hz EMFs may alter cell cycle and induce apoptosis of mouse brain and liver cells.

Animals↗

Pulsed electromagnetic fields accelerate apoptotic rate in osteoclasts.

Selective control of cell function by applying specifically configured, low-energy, time-varying electromagnetic fields (EMF) has added a new, exciting dimension to biology and medicine. However, the mechanism involved is less clear. In our study, we investigated the effect of pulsed electromagnetic fields (PEMF) on induction of osteoclasts apoptosis. A statistically significant increase of apoptotic rate in osteoclasts (48 hr after isolation) was found when exposed to 7.5 Hz PEMF with induced electric fields intensity of 3.0 muv/cm for 8 (105%, p < 0.001) and 16 hr (30%, p < 0.05). However, exposure of osteoclasts to PEMF for only 1 hr showed no statistically significant differences. These findings suggest that PEMF have the ability to speed up apoptosis of osteoclasts derived from primary osteoblasts and bone marrow cells cocultures. This in vitro study, therefore, could be considered as groundwork for in vivo PEMF applications on some osteoclasts-associated bone diseases such as osteoporosis.

Animals↗

A preliminary study on ultra high frequency electromagnetic fields effect on black locust chlorophylls.

Chlorophylls were quantitatively studied in the leaves of black locust (Robinia pseudoacacia L.) seedlings exposed to electromagnetic fields of high frequency. Exposure system was designed and built up to make possible simultaneous exposure of seedling lots (3 months old) to low power density electromagnetic fields corresponding to a frequency of 400 MHz. After three weeks of daily exposures (1, 2, 3 and 8 hours), chlorophyll levels were measured using adequate spectral device. Statistical analysis of experimental results was performed by means of t-test to identify significant modifications induced by electromagnetic treatment in exposed samples in comparison to the control. Chlorophyll-a as well as chlorophyll-b level was found to decrease except the exposure time of two hours, where a considerable enhancement was noticed. It was revealed that the ratio of the two main types of chlorophyll was decreasing logarithmically to the increase of daily exposure time.

Chlorophyll↗

[Reaction of the endocrine system to continuous and intermittent electromagnetic fields].

This paper reviews Soviet and foreign data about the effects of low frequency electromagnetic fields of continuous and intermittent generation on the endocrine system of animals and humans. It has been shown that the pituitary-adrenal, pituitary-thyroid and reproductive systems are sensitive to these effects. It is postulated that the endocrine responses to electromagnetic effects are similar to the general adaptive reactions to various pathophysiological exposures.

Animals↗

Occupational exposures to high frequency electromagnetic fields in the intermediate range ( >300 Hz-10 MHz).

The aim of this study was to identify work situations with electromagnetic fields of 300 Hz-10 MHz and to characterize the occupational exposure. Work place investigations included descriptions of the work environment and physical measurements. We estimated electric (E) and magnetic (H) fields by spot measurements in air, by logged exposure data, and when possible, we recorded induced currents in limbs. The instruments used were Wandel and Golterman EFA-3, NARDA 8718, Holaday HI-3702. The exposure sources comprised five induction furnaces, seven induction heaters, one surface treatment equipment, four units of electronic article surveillance (EAS), and medical devices for surgery and muscle stimulation. The induction furnaces operated at 480 Hz-7 kHz, and the maximum values of logged data varied between 512-2,093 V/m (E field) and 10.5-87.3 A/m (H field). The induction heaters (3.8 kHz-1.25 MHz) also showed high maximum exposure values of both E and H fields. Three EAS units, an electromagnetic plate at a library, a luggage control unit, and an antitheft gate, showed E fields reaching 658-1,069 V/m. The H fields were comparatively lower, except for the antitheft gate (5 and 7.5 kHz) showing a maximum value of 27.2 A/m (recorded during repair). Induced currents of 5-13 mA were measured for the medical devices. The study improves the basis for an exposure assessment for epidemiological studies of long term effects of exposures to high frequency electromagnetic fields.

Diathermy↗

Electromagnetic fields and melatonin production.

The pineal gland, which in humans is located near the anatomical center of the brain, is normally responsive to visible electromagnetic fields (ie light) since the eyes are functionally connected to the pineal gland by a series of neurons. Normally, the pineal gland produces low amounts of melatonin during the day and high amounts at night; this rhythm is reflected in the blood melatonin concentrations which are higher at night than during the day. In both man and lower mammals, their exposure to light at night is followed by a drop in pineal melatonin production and blood melatonin levels. Likewise, exposure of non-human mammals to sinusoidal electric and/or magnetic fields as well as pulsed static magnetic fields often reduces pineal melatonin production. Melatonin has many functions in the organism and any perturbation (not only electromagnetic fields) which causes levels of melatonin to be lower than normal may have significant physiological consequences. Melatonin, because it is a potent antioxidant, may provide significant protection against cancer initiation as well as promotion. However, it is premature to conclude that the alleged increased cancer risk reported in individuals living in higher than normal electromagnetic environments relate to reduced melatonin levels caused by such field exposures.

Animals↗

[The influence of a low- and high-frequency electromagnetic fields on seeds].

It was shown that the exposure of seeds in the rest phase to a low-frequency pulse electromagnetic field leads to substantial changes in seed physiology during germination. The changes at the physiological level in sprouting seeds depend not only on the frequency of the external EMF and its power characteristics but also on the kind of seeds. Low- and high-frequency electromagnetic fields are able to produce a biostimulation effect; however, the mechanisms of its appearance are different in their nature. The biochemical studies of seeds after EMF treatment in the modes resulting in expressed biological effects showed an increase in the activity of alpha-amylase, which testifies an increase in the gibberellin output and in the activity of the hydrolytic enzyme sour phosphatase. The response of seeds to EMF treatment demonstrates the possibility of electromagnetic control of growth processes.

Acid Phosphatase↗

Pulsing electromagnetic fields (PEMFs) in spinal fusion: preliminary clinical results.

Pulsing electromagnetic fields (PEMFs) were used during the postoperative management of 31 patients submitted to lumbosacral posterolateral fusion (PLF). The fusions were stimulated with PEMFs during the first 2 of the 4 months of postoperative immobilization. Consolidation of PLF was obtained in 20 of the 31 patients after 2 months of stimulation, thus, healing time was cut in half. After 4 months, fusion was observed in 30 out of the 31 cases submitted to stimulation (96%).

Adult↗

Patient reactions to some electromagnetic fields from dental chair and unit: a pilot study.

The aim of this study was to investigate whether experienced changes of symptoms could be correlated with electromagnetic fields from dental equipment. Five patients, who had reported an intensification of symptoms during exposure to electromagnetic fields, participated in this doubleblind study. In two sittings with an interval of two months the patients were seated for one hour in a dental chair with fixed unit. For blinding reasons, the chair, unit, and ceiling lights were stripped or unlit. The magnetic fields from the room, chair, and unit had been measured both with and without electric supply. The difference in magnetic field intensity was, at some points of measurement, very large. Neither the patient nor the investigator knew when the electric supply was on or off. During the first sitting, the supply was off the entire hour; during the second sitting, the supply was on the entire hour. All five patients experienced intermittent exposures during the first one hour sitting. Those four participating in the second test experienced the same intermittent exposures as in the first sitting. This pilot study failed to demonstrate a correlation between exposure from some magnetic fields of the dental chair and unit under operating control and experienced hypersensitivity reactions.

Dental Equipment↗