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Results for “Tooth Abnormalities”

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PubMed1991

Dental anomalies in fucosidosis.

Dental anomalies have not previously been recorded in patients with fucosidosis. A new case of this rare disorder is reported, in which a number of variations in both number and morphology of the primary and secondary dentition occur.

Child, Preschool↗
PubMedDate not supplied

The presentations and management of transposed teeth.

Tooth transposition is an uncommon dental anomaly that nevertheless has important implications regarding treatment. This article describes six types of transposition, discussing the problems and possible solutions. It is important to ensure that the results of any treatments for transposition are both aesthetic and functional.

Child↗
PubMed1997

Secondary retention of multiple permanent teeth.

An unusual case of secondary retention of multiple permanent teeth is reported. The clinical, radiographic and histological findings associated with this condition, and its management, are discussed.

Adult↗
PubMed2002

Identification of a locus on chromosome 2q11 at which recessive amelogenesis imperfecta and cone-rod dystrophy cosegregate.

A consanguineous Arab pedigree in which recessive amelogenesis imperfecta (AI) and cone-rod dystrophy cosegregate, was screened for linkage to known retinal dystrophy and tooth abnormality loci by genotyping neighbouring microsatellite markers. This analysis resulted in linkage with a maximum lod score of 7.03 to the marker D2S2187 at the achromatopsia locus on chromosome 2q11, and haplotype analysis placed the gene(s) involved in a 2 cM/5 Mb interval between markers D2S2209 and D2S373. The CNGA3 gene, known to be involved in achromatopsia, lies in this interval but thorough analysis of its coding sequence revealed no mutation. Furthermore, affected individuals in four consanguineous recessive pedigrees with AI but without CRD were heterozygous at this locus, excluding it as a common cause of non-syndromic recessive AI. It remains to be established whether this pedigree is segregating two closely linked mutations causing disparate phenotypes or whether a single defect is causing pathology in both teeth and eyes.

Amelogenesis Imperfecta↗
PubMed1996

Transposition of teeth and genetic etiology.

Twenty-one cases of transposition are presented showing a crude prevalence of 0.4%. A high rate of bilateral occurrence was seen. A significant number of cases were associated with other dental anomalies, such as peg-shaped lateral incisors and overretained deciduous teeth. Genetic etiology has been stressed and various other theories discussed.

Adolescent↗
PubMed1998

Class II Division 2 malocclusion: a heritable pattern of small teeth in well-developed jaws.

Angle's designation of the Class II Division 2 (II/2) malocclusion recognizes a unique combination of overbite, incisor retroclination, and sagittal discrepancy. A very severe II/2 phenotype, characterized by concealment of the mandibular incisors in occlusion, has been called Deckbiss in German, or cover-bite. In this report, the cover-bite malocclusion is studied to identify morphological factors associated with Angle's II/2 occlusal discrepancy. Selected X-ray cephalometric and odontometric measurements were recorded for 23 subjects (M14; F9) with II/2 cover-bite malocclusion. Data were compared with those from a control-reference sample of 537 individuals. Cephalometrically, the II/2 cover-bite sample showed a pattern of strong vertical posterior development of the mandible with forward-rotation and skeletofacial hypodivergence (p < 0.0001). Anteroposteriorly, the maxillomandibular dentoalveolar relationship was relatively normal, and the basal bone region of the mandibular corpus appeared significantly well developed anteriorly, accounting for excessive bony chin projection (p < 0.0001). Dentally, mesiodistal tooth diameters for the maxillary and mandibular incisors of the II/2 cover-bite sample were significantly smaller than those of the reference sample (p < 0.002), pointing to systematically reduced tooth-size as a trait associated with II/2 malocclusion. These findings of a characteristic pattern of heritable skeletal and tooth-size features in II/2 cover-bite malocclusion indicate the presence of strong genetic influences in the formation of Angle's II/2 deep-bite discrepancy.

Adolescent↗
PubMed1998

A controlled study of associated dental anomalies.

The purpose of this study was to reveal patterns of association among seven types of dental anomalies (aplasia of second premolars, small size of maxillary lateral incisors, infraocclusion of primary molars, enamel hypoplasia, ectopic eruption of first molars, supernumerary teeth, and palatal displacement of maxillary canines) in an untreated orthodontic population, ages 7 to 14. The prevalence of associated tooth anomalies in seven groups of 100 subjects selected according to one primarily diagnosed dental anomaly was compared with the prevalence of the examined dental anomalies in a control group of 1,000 subjects. Significant reciprocal associations (p < 0.005) were found among five of the anomalies (aplasia of second premolars, small size of maxillary lateral incisors, infraocclusion of primary molars, enamel hypoplasia, and palatal displacement of maxillary canines), suggesting a common genetic origin for these conditions. Supernumerary teeth appeared to be a separate etiological entity with respect to all other examined tooth anomalies. The existence of associations between different tooth anomalies is clinically relevant, as the early diagnosis of one anomaly may indicate an increased risk for others.

Adolescent↗
PubMed1998

Mandibular lateral incisor-canine transposition, concomitant dental anomalies, and genetic control.

Mandibular lateral incisor-canine (Mn.I2.C) transposition is a rare developmental disturbance of tooth order characterized by positional interchange of the two teeth. In children with Mn.I2.C anomaly, the mandibular lateral incisor shows distal ectopic eruption and the adjacent canine subsequently erupts mesial to it. A sample of 60 orthodontic patients with Mn.I2.C transposition was studied using roentgenograms taken at the time of diagnosis. Two age-related phenotypes of the anomaly were identified: early-stage (median age, 9 years) and mature-stage (median age, 12 years). Mn.I2.C transposition occurred bilaterally in 10 subjects (17%) and favored female expression (sex ratio, M1:F3) and right-side occurrence (68% of unilateral cases). Statistically significant associations were found between Mn.I2.C transposition and increased frequency of tooth agenesis (M3, p < 0.01; MnP2, p < 0.01) and peg-shaped maxillary lateral incisors (p < 0.0001). The results from this study and the analysis of 50 previously published cases provide evidence that Mn.I2.C transposition is a disturbance of tooth order and eruptive position probably caused by genetic influences. The Mn.I2.C anomaly likely results from genetic mechanisms similar to those responsible for occurrences of its associated dental anomalies, such as tooth agenesis and peg-shaped maxillary lateral incisors. In an appendix, clinical orthodontic management of Mn.I2.C transposition is discussed, based on treatment data derived from the study sample.

Adolescent↗
PubMed2000

Prevalence of tooth transposition, third molar agenesis, and maxillary canine impaction in individuals with Down syndrome.

Alterations in the size, morphology and number of teeth are among the many inherited disorders that have been reported in individuals with Down syndrome. By contrast, third molar agenesis and tooth transposition have been largely ignored and the prevalence of canine impaction has not been reported. The intention of this study was to quantify the occurrence of these anomalies in a group of individuals with Down syndrome, using standardized records, which included a clinical examination, dental casts, and a panoramic radiograph. The results show a notably high prevalence of third molar agenesis (74% of individuals older than 14 years), canine impaction (15%), and maxillary canine/first premolar transposition (15%), compared to published figures from random population samples. These anomalies should not be seen as separate, independent entities, but as associated phenomena. The slow rate of cell growth and a consequent reduced cell number that characterize this syndrome may be responsible for the underdevelopment of the upper jaw, the delayed dental development, the reduction in teeth number and size, and the altered path of canine eruption. No explanation, other than genetics, is immediately available to explain why the maxillary canine/first premolar transposition should represent another phenotypic expression of this trisomy.

Adolescent↗
PubMed2003

Orthodontic and orthopedic treatment of a patient with incontinentia pigmenti.

Incontinentia pigmenti is an uncommon, inherited disorder with predominantly ectodermal manifestations that is associated with skin (100%)), dental (90%), skeletal (40%), central nervous (40%), and ocular (35%) deformities. It is an X-linked dominant disease, usually lethal in males and occurring in female infants. The dental effects include delayed eruption, partial anodontia, microdontia, and cone or peg-shaped teeth. The dental, clinical, and radiological findings in a 16-year-old female are presented here. The patient had peg-shaped teeth and a unilateral maxillary transverse discrepancy associated with oligodontia in the maxillary and mandibular arches. Orthodontic treatment included rapid maxillary expansion and fixed orthodontic therapy for prosthetic purposes and elimination of the functional midline shift.

Adolescent↗
PubMed2004

Dentoskeletal features associated with unilateral or bilateral palatal displacement of maxillary canines.

The aim of the present study was to analyze the prevalence and distribution of palatally displaced maxillary canines (PDC) in a large orthodontic population, and to investigate the associations between PDC, craniofacial features, and other dental anomalies such as aplasia or small-sized upper lateral incisors. An initial sample of 5000 subjects was evaluated. The reference values were calculated in a control group of 1000 subjects that was extracted from the initial sample. Chi-squared tests were used for statistical comparisons. The prevalence rate of PDC was 2.4%, with a male-to-female ratio of 1:3. PDC subjects with low angle vertical relationships showed a significantly high prevalence rate (60.2%). Unilateral PDC was significantly associated with aplasia of upper lateral incisors, whereas bilateral PDC was associated with aplasia of third molars. PDC showed reciprocal significant associations with bilateral small-sized upper lateral incisors. None of the three hypotheses offered in support of the "guidance theory" in the etiology of PDC were corroborated by the findings of the present study. The occurrence of other dental anomalies concurrent with PDC, sex differences, and the bilateral expression of PDC, all confirm the genetic component in the etiology of this tooth disturbance.

Adolescent↗