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[Thrombosis and thrombophlebitis after catheterization of the subclavian vein].

The authors analysed 685 catheterizations of the subclavian vein. Thrombophlebitic complications were diagnosed in 13 patients--phlebothrombosis in 9 of them and thrombophlebitis in 4. The complications developed mostly in cases with a severe general disease, in ++pyo-septic conditions. In 19 patients the catheter was displaced into the internal jugular vein during phlebography. Catheterization had to be repeated in 73 patients, thrombophlebitic complications occurred in 4 of them. A conclusion is drawn on the expediency of the principle of unilateral manipulations in catheterization repeated many times.

Aged↗

Pulmonary embolism secondary to puerperal ovarian vein thrombophlebitis.

Four cases of pulmonary embolism (PE) secondary to puerperal ovarian vein thrombophlebitis (POVT) were treated surgically during the first semester 1990. Clinical features are described in detail. The diagnosis was made by echotomography in three cases, but the crucial examination was contrast phlebocavography in all the subjects. Ovarian vein ligation, caval thrombectomy and inferior vena cava interruption by DeWeese clip positioning was the operation performed in any cases. Postoperative courses were always uneventful and three to six months follow-up was available. The extensive practice of echotomography during the first week of puerperium could demonstrate that POVT is more frequent than previously thought.

Adult↗

Superficial thrombophlebitis diagnosed by duplex scanning.

Since July 1982, this noninvasive vascular laboratory has performed 12,856 lower extermity venous duplex examinations. All cases of acute venous thrombosis have been categorized and entered into a computer data base. One thousand four hundred twelve examinations were positive for acute venous thrombosis. This report analyzes the laboratory's entire experience with superficial thrombophlebitis (SVT). One hundred eighty-six patients were diagnosed by duplex scanning to have SVT. Women outnumbered men 99 to 87. They were slightly older (average age 58.4 +/- 16.2 years) compared with the men (53.8 +/- 14.2 years). Men were more likely to have a complicated course of SVT (40% vs 22%; p less than 0.01). Complications included either radiographically documented pulmonary embolism or deep venous involvement. Fifty-seven (31%) patients had at least one complication of SVT. A series of predisposing factors was analyzed and six factors were associated with an increased risk of complications. They are bilateral SVT (p less than 0.01), age greater than 60 years (p less than 0.01), male sex (p less than 0.01), history of deep venous thrombosis (p less than 0.01), bed rest (p less than 0.02), and presence of infection (p less than 0.02). Location of thrombus within the greater saphenous vein (35%) was most likely to be associated with complications. Isolated varicosities (8%) were least likely to be associated with complications. Duplex scanning identifies a significant number of complications of patients with SVT and should be obtained in cases of saphenous vein involvement or in the presence of associated risk factors.

Aged↗

[The transcutaneous treatment of superficial thrombophlebitis with the exogenous nitric oxide donor: nitroglycerin].

Nitroglycerin (glyceryl trinitrate) is a substance that is metabolized to nitric oxide in the cell. Its action is not dependent of the endothelium derived nitric oxide, but imitates those of this biological mediator. We thought that nitroglycerin should have the same in vivo actions as the endogenous nitric oxide in vitro has. We report and discuss the first patient with superficial thrombophlebitis successfully treated with transdermal nitroglycerin.

Acute Disease↗

[Therapeutic procedure for tuberculous thrombophlebitis].

The author describe five cases of thrombophlebitis unchained for the bacillus of Koch, which first focus was not detected through the methods of search often used in this kind of work. It's a very rare peripheral vascular disease. The clinical manifestations which follows its installation has in the pain its most important symptom. The surgical resection of the vein was the most suitable conduct with the present pathological reality, once the clinical measures were unable to bring satisfactory results.

Adolescent↗

Superficial migratory thrombophlebitis.

Clinical and histologic characteristics of superficial migratory thrombophlebitis are demonstrated in this report of a thirty-five-year-old man who showed recurring tender linear erythematous lesions of the lower extremities. The importance of investigating patients with this condition for evidence of associated diseases, particularly malignancy, is emphasized.

Adult↗

[The significance of computed tomography and ultrasound in the diagnosis of puerperal ovarian vein thrombophlebitis].

The diagnosis of puerperal ovarian venous thrombophlebitis (POVT) is problematic, not only because of the low and variable incidence (1:600-6000 births), but also because there are no characteristic clinical symptoms. So far, therefore in 80% of cases it has been diagnosed by exploratory laparatomy. Early non-invasive diagnostic procedures must be aimed at, because surgical intervention involves a high rate of complications and uncomplicated cases can be treated by conservative methods (broad-spectrum antibiotics and anti-coagulants). Several case reports refer to the possibility of recognizing POVT by real-time ultrasound (US) and computer tomography (CT). Two cases are described to illustrate this option for preoperative diagnosis by CT and US. A tubular, annular structure with ring enhancement after application of dye along the anatomical course of the ovarian vein seems to be characteristic for POVT.

Adult↗

[Indications for surgical treatment of acute superficial thrombophlebitis].

The acute superficial thrombophlebitis (AST) which may be considered as an "aseptic local inflammatory reaction to vein thrombosis" is a very common disease. The diagnosis of this illness is simple, and usually consists of anamnesis and physical examination. This is due to the fact that typical external signs of inflammation are always present. In such cases the conservative treatment was usually recommended and it included rest, elevation, alcoholic compresses, antipyretic and analgetic drugs. The operative treatment was carried out only if the process developed near the deep vein system, or if a suppurative inflammation was present. We believe that wider indications for operative treatment should be considered. We base this statement on the following facts: the operative finding always shows that the process is greater than we suppose after physical examination, and the operation is easier to perform before scar tissue has been formed at sites of inflammation. The following indications are considered for conservative treatment: AST of the upper limbs; AST of the lower limbs where the great saphaenous vein is not included; AST of the lower limbs including the great saphaenous vain on the level above the knee; Suppurative forms of AST. We plead for one act operation which shortens the time of hospitalisation and includes: Crosseectomia; Ligature, resection and extirpatin of the great saphaenous vein (Vasalve).

Acute Disease↗

[The modification of injection pain and the incidence of thrombophlebitis following etomidate].

A prospective study with 161 patients was performed to investigate the effects of intravenous local anaesthetics on the pain of injection following etomidate injection. After placebo injection 56.6% of the patients reported on pain after etomidate, but only 29% after 20 mg lidocaine i.v. Lidocaine combined with venous congestives significantly reduced the incidence of pain to 3.35%. A dilution of etomidate with water (ratio 1:1) had a lower effect (17.6% incidence of pain). The rate of postoperative thrombophlebitis was lowest in the group with combined lidocaine with venous congestives at 7.4%, in opposition to a rate of 18% in the remaining groups. In comparison to a second contralateral venous cannula without applied etomidate the venous sequelae did not increase significantly.

Adult↗

Simultaneous occurrence of superficial and deep thrombophlebitis in the lower extremity.

Forty-two consecutive patients diagnosed with superficial phlebitis were seen during a 5-year period. Thirty-five of the 42 patients were outpatients. The diagnosis of superficial phlebitis was made by the presence of palpable subcutaneous cords in the course of the greater saphenous vein or its tributaries in association with tenderness, erythema, and edema. The presence of concurrent deep venous thrombosis (DVT) was assessed by impedance plethysmography in 37 patients, compression venous ultrasonography in 3 patients, and venography in 8 patients. Five of the 42 patients (12%) had DVT. Four of these five patients had a positive impedance plethysmographic or ultrasonographic test result followed by a confirmatory venogram. The fifth patient had a positive ultrasonographic test result, but no venogram was performed. Two of the five patients had clots that involved the popliteal or femoral veins. Four of 23 patients (17%) with superficial phlebitis at or above the knee had DVT. Only 1 of the 19 patients (5%) with superficial phlebitis below the knee had DVT. Three of the five patients with both superficial phlebitis and DVT had undergone surgery recently. All but 3 of the 42 patients (93%) had varicose veins. No patients had clinically apparent pulmonary emboli. DVT occurred in 17% of the patients with above-knee extension of the superficial phlebitis. In the clinical management of superficial lower-limb thrombophlebitis, noninvasive tests should be performed to guide therapy. When superficial phlebitis develops after recent surgery or the superficial phlebitis extends above the knee, diagnostic surveillance should be especially strict. When the noninvasive test results are equivocal, phlebography is indicated to rule out DVT.

Female↗

[Peripheral thrombophlebitis. "Paratuberculous syndrome" (author's transl)].

The authors relate the case of a young North-African man who presented during one month several peripheral thrombophlebitis before a ganglionary tuberculosis of the mediastinum appear. With specific antibiotherapy, the cutaneous lesions disappear and can be so considered as a paratuberculous syndroma.

Adult↗

[Granulomatous thrombophlebitis in Lyme borreliosis--case report].

The presented case report shows a patient with Lyme disease who also developed thrombophlebitis saltans. Histopathologically we found a granulomatous perivasculitis, an immunohistological investigation showed deposits of IgG, IgA, IgM, C3 and C4 in the vessels. Antibody titers against Borrelia burgdorferi were elevated, but no anti-cardiolipin antibodies were found. A pathogenetic correlation due to anti-phospholipid antibodies that have been found in thrombosis and borreliosis or a vasculitis vasorum comparable to a previously described vasculitis nervorum might be discussed.

Antibodies, Bacterial↗

[Deep thrombophlebitis in polycythemia and uterine fibromyoma].

A case of thrombophlebitis in the lower extremity caused by a large uterine fibromyoma which produced secondary polycytaemia is described. It is concluded that control of Hb and erythrocyte volume fraction is necessary in patients with uterine fibromyoma. In cases of polycytaemia, hysterectomy is recommended after treatment of the polycytaemia. Examination of patients with a secondary polycytaemia includes gynaecological examination.

Female↗

Thrombophlebitis. Prevention, recognition, and management.

Thrombophlebitis is a common disease entity with characteristic features of edema, inflammation, and tenderness. If the disease process is extensive, the postphlebitic syndrome, which is characterized by persistent edema, pigmentation, dermatitis, ulceration, and varicose veins, invariably occurs.

Anticoagulants↗

[Primary exertion thrombophlebitis of the upper extremities: clinical and therapeutic aspects].

The authors present 4 cases of "effort" thrombophlebitis of the upper limb that were diagnosed both clinically and thrombophlebographically, and in whom classical therapy was applied: total rest, anticoagulants, elevation of the limb. All the cases had sequels of variable intensity, and in 2 of the patients Roos' transaxillary route was used which revealed a double anterior scalenus muscle insertion, and compressive fibro-sclerous tissue. The pathogeny of the affection makes mandatory the removal of extrinsic or intrinsic factors which may generate a new thrombosis or vascular and neurologic sequels.

Adult↗

Infusion thrombophlebitis--histological and bacteriological study.

In a study conducted over a four year period, 99 developed thrombophlebitis of the total of 560 intravenous infusions under similar infusion conditions. In all the patients who developed phlebitis, fluid from the bottle, first 5 ml. of fluid from the infusion set after removing the drip and the needle itself were subjected to bacteriological study. Only in two cases the culture was positive, indicating it was a non-bacterial inflammation. The vein was subjected for histopathology after obtaining a small segment. Histopathology showed thrombus in the lumen of the vein in the majority of the cases, destruction of endothelial lining with pyknosis of nuclei and leucocyte infiltration in the media.

Adolescent↗

[Treatment of acute thrombophlebitis of the lower limbs with laser irradiation].

Low-intensity helium-neon laser (LG-75) radiation produces a marked analgesic, desensitizing, hypocoagulative, and immunostimulating effect, which can be used in the treatment of acute thrombophlebitis of the lower limbs. Laser therapy alters the phase course of the wound process and in this way improves microcirculation and oxygenation of the tissues, shortens the terms of wound healing, and may be used as the method of choice in the treatment of trophic ulcers of the lower limbs.

Acute Disease↗