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Implicit learning and concept learning.

In Experiments 1 and 2, subjects were exposed to letter strings that followed a pattern--the second letter was always the same. This exposure was disguised as a test of immediate memory. Following this training, subjects could discriminate new letter strings following the pattern from letter strings not following the pattern more often than would be expected by chance, which is the traditional evidence for concept learning. Discrimination was also better than would be predicted from subjects' explicit report of the pattern, demonstrating the co-occurrence of concept learning and implicit learning. In Experiment 3, rules were learned explicitly. Discrimination was worse than would be predicted from subjects' explicit report, validating the implicit learning paradigm. In Experiment 4, deviations from a prototypical pattern were presented during training. In the test of discrimination, prototypes were as familiar as old deviations and more familiar than new deviations, even when considering only implicit knowledge. Experiment 5 found implicit knowledge of a familiar concept. These results are consistent with the hypothesis that the distinguishing features of a concept can be learned implicitly, and that one type of implicit learning is concept learning.

Adult

Encoding strategies used by young and elderly adults in a keeping track task.

College students and older adults (mean ages 20.4 and 71.5 years) performed in a "keeping track" task that required them to recall, in response to probe questions, the most recently presented of each of a fixed set of categories. Questions alternated with presentations of new sets of items. Response accuracy, reaction times, and verbal reports provided information on the participants' strategies. The findings were consistent with the view (e.g., Hasher & Zacks, 1979) that older adults' poorer memory results from reduced use of effortful strategies. The older persons used fewer active encoding strategies than the college students and were less accurate and slower to respond. A subgroup of the elderly adults reported some active encoding activities; they performed more like the college students than the remaining elderly participants. A follow-up study in which college students were allowed reduced opportunity for active encoding produced performance intermediate between the other two groups.

Adolescent

Assessment of cognitive asymmetries in brain-damaged and normal subjects: validation of a test battery.

A test battery designed to assess cognitive functions normally related to the left and right cerebral hemispheres was validated on 30 patients with unilateral (16 right, 14 left) lesions. The tests were preselected to reflect typical functioning of the hemispheres according to general agreement in the literature. A Cognitive Laterality Quotient (CLQ) was calculated from the difference in performance between the "right" and "left" test batteries and, therefore, reflected the relative functioning attributed to the right and left hemispheres. Using the CLQ measurement and a control group of 30 non-neurological patients matched for age and education, 28 out of 30 brain-damaged patients (93%) were categorised correctly according to side of lesion; the other two were considered to have either abnormal lateralisation (one was left handed) or asymmetrical premorbid cognitive profiles. Using only one (paired) test whose two subparts were designed to vary only slightly in task requirements to measure either right or left functioning, 29 out of 30 patients were correctly categorised. It is suggested that the concept of relative assessment of basic cognitive functions is more fruitful than general assessment of intellectual functions for use in diagnosis and rehabilitation of neurological patients or normal subjects with developmental or acquired behavioural cognitive abnormalities.

Adult

Effect of multimodal stimulus presentation on recall.

This study was conducted to investigate how the mode of stimulus presentation affects recall in the classroom environment. 289 undergraduates were randomly assigned to one of 7 experimental groups. All subjects were presented the same stimuli in one of 7 possible modes: (1) Printed Word, (2) Spoken Word, (3) Picture, (4) Printed Word + Spoken Word, (5) Picture + Spoken Word, (6) Picture + Printed Word, and (7) Printed Word, Picture + Spoken Word. 30 words, 6 from each of 5 categories, were presented to each group. A new stimulus was presented every 5 sec. Subjects were to recall (in writing) as many stimuli as possible in 5 min. regardless of order. One-way between groups analyses of variance were conducted on recall and cluster index scores. A significant main effect of mode of presentation showed that recall was best for the Picture or multimodal group (Printed Word, Picture + Spoken Word). Groups receiving only the spoken or printed word showed significantly poorer recall than the multimodal groups. No statistically significant differences between groups were found on the cluster index score. It appears that the simultaneous presentation of redundant stimuli in multiple modalities does support the multiple-resource hypothesis by displaying enhanced recall when information is available from multiple attentional resources.

Adolescent

Memory for temporal order in schizophrenia.

Memory for temporal order information was examined in patients with chronic schizophrenia using the recency discrimination task. In this task, subjects were shown a pair of previously studied words and were asked to choose which one of the two words they had seen more recently. In addition, subjects performed the Wisconsin Card Sorting Test (WCST). The results showed that schizophrenic patients differed from normal control subjects in their performance on the recency discrimination task. In addition, for schizophrenic patients, performance on the recency discrimination task was inversely related to the number of perseverative errors on the WCST. These results provide further evidence of prefrontal-type cognitive deficits in schizophrenia.

Adult

Aetiological variation in the amnesic syndrome: comparisons using the list discrimination task.

In this study, the performance of amnesic patients with presumed temporal lobe damage was compared with that of patients with presumed diencephalic damage using the temporal list discrimination task. The two patient groups performed similarly on a measure of recognition, but the diencephalic group was impaired relative to the temporal lobe group on a measure of temporal discrimination. Discrimination performance in the temporal lobe group was significantly correlated with recognition memory. The data are interpreted as showing a qualitative difference in the form of amnesia arising from damage centred on the medial temporal lobes compared with that centred on the midline diencephalon.

Adult

The effects of lesions to the fornix and dorsomedial thalamus on concurrent discrimination learning by rats.

Rats with lesions in either the fornix or the thalamic nucleus medialis dorsalis were unimpaired on the acquisition of two object discrimination tasks. The same animals were then tested on a concurrent learning task in which various object discriminations were presented at different rates during the same session. This arrangement was primarily designed to minimise any response bias effects. Animals were able to acquire the various concurrent tasks, even when only one trial per day was given for a particular discrimination. It was found that fornix lesions had little or no effect and only produced a mild impairment when the rate of stimulus presentation resembled that used in typical concurrent tasks. Lesions of medialis dorsalis produced a more general, but again mild, deficit. In a final task, the animals were trained to discriminate between two stimuli composed of common elements arranged in different spatial combinations. Fornix lesions impaired acquisition of this spatial configural discrimination, while lesions of medialis dorsalis had a variable effect. The results indicate that fornix lesions can spare concurrent discrimination learning, and that any deficits may be related to interference effects associated with common elements in the stimuli. Lesions in medialis dorsalis appear to affect the initial learning of reward-based performance rules.

Animals

Dissociation of item and order memory following parietal cortex lesions in the rat.

Rats with parietal cortex lesions were tested for both item and order memory for a list of spatial events in a probe recognition procedure. Rats with parietal cortex lesions were impaired for all events within the item memory task but had good memory for the early events within the order memory task. These data suggest a dissociation of function between item and order memory for parietal cortex damaged animals. In conjunction with previous findings with rats with medial prefrontal cortex lesions, these data suggest that item and order memory can be coded and represented independently.

Animals

Further studies of hippocampal representation during odor discrimination learning.

The contribution of hippocampal and nonhippocampal memory processing to simultaneous-cue odor discrimination learning was assessed. In this task, rats with hippocampal system damage consequent to fornix lesions (fornix rats) were severely and persistently impaired in discrimination learning, acquisition of learning set, and concurrent discrimination, although they occasionally solved some problems at a normal rate. By using those problems on which fornix rats succeeded, to permit comparisons of performance strategies with normal rats, differences between groups were shown on response latency measures and on probe trials involving the novel pairing of familiar odors. Normal rats had a bimodal distribution of response latencies, and their latency depended on where the S+ was presented. Fornix rats had short response latencies and responded equally quickly wherever the S+ was presented. Furthermore, when the representation of familiar S+ and S- odor pairs was challenged in probe trials, normal rats responded appropriately to the correct stimulus, whereas fornix rats behaved as if presented with a new odor pair. These data provide support for the view that the hippocampus participates in the representation of relations among odor (and other) stimuli and among other experiences and that it permits the flexible use of these representations in new contexts. In contrast, memory processing outside the hippocampal system can represent only the significance of individual stimuli and can be revealed only in a repetition of the original learning event.

Animals

Some cognitive effects of frontal-lobe lesions in man.

The study of patients undergoing unilateral frontal-lobe excisions for the relief of focal epilepsy has revealed specific cognitive disorders that appear against a background of normal functioning on many intellectual, perceptual and memory tasks. Lesions that invade the frontal eye field cause subtle impairments of voluntary oculomotor control, which reveal themselves as an inability to suppress an initial glance at a potentially distracting stimulus. After frontal lobectomy in either hemisphere, deficits are found quite consistently on motor-differentiation tasks (Konorski 1972) in which the subject must learn to produce different responses to different, randomly presented, environmental signals. More directly related to the concept of planning are those sequential tasks in which the subject is free to choose his own order of responding, but must not make the same response twice. Here the left frontal lobe plays the major role, a finding consistent with the notion of left-hemisphere dominance for the programming of voluntary actions. In contrast, the right frontal lobe appears to be more critically involved in monitoring the temporal sequence of externally ordered events, although the verbal or non-verbal nature of the stimuli remains a relevant factor.

Adult

Intravenous diazepam in humans: effects on acquisition and performance of response chains.

A technique based upon an individual-subject design was used to investigate the effects of intravenous diazepam on the acquisition and performance of response chains in humans. In each of two conditions subjects were required to emit a different sequence of ten responses in a predetermined order on three levers. The conditions alternated within each session under a multiple schedule. In the performance condition the sequence of responses was the same each session. The second condition was a repeated-acquisition task. In this condition subjects were required to learn a different sequence of responses each session. Diazepam produced dose-dependent decreases in the overall rate of responding in each subject under both conditions. In two of the three subjects tested, errors were increased in the learning condition at doses lower than those required to disrupt accuracy in the performance condition. In one subject, accuracy in both the learning and performance conditions was equisensitive to the disruptive effects of diazepam. These data are consistent with the effects of the benzodiazepines in analogous animal procedures. Furthermore, the data suggest that the behavioral effects of intravenous diazepam may exhibit marked variations across subjects at clinically relevant doses (5-10 mg).

Adult