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Recent status of stereotaxic surgery.

Another important technical advance is the development of computed tomography (CT) instrumentation. The most recent equipment is able to detect lesions 2 mm in diameter. When the stereotaxic frame is exactly adjusted to the CT axis, the structures in the depth of the brain can be visualized and localized and can be referred to the three-dimensional coordinates of the stereotaxic instrument. This will enable the exact insertion of the stereotaxic needle to a small tumor lying in the depth of the brain or to some type of vascular lesions. Three-dimensional angiography would also provide the detailed information about such deep-lying tumors and their blood supply. It is highly probable that further advances in tomographic instrumentation will take the place of pneumoventriculography or positive contrast ventriculography, even in cases of functional stereotaxis. However, the importance of using the sophisticated physiologic methods previously described remains the same. At present, these new developments are still at the stage of designing instrumentation. Much is expected in the future. In summary, stereotaxic surgery is a selective technique to approach deep-lying structures in the human brain. It enables us to examine and treat the pathology in the depth of the brain. The important and necessary attitude of the scientist is how to understand the nature of the symptoms and the diseases, on which the prognostic value of the lifelong treatment may depend.

Brain Diseases↗

A stereotaxic x-ray map of the hypothalamus of the marmoset monkey Callithrix jacchus.

Precise hypothalamic surgery in the marmoset monkey Callithrix jacchus cannot be performed by means of the Horsley-Clarke stereotaxic procedure. Thus, a simple stereotaxic X-ray technique was developed. Technical requirements are a stereotaxic frame for small animals and a dental X-ray source. A sagittal map shows hypothalamic structures in relation to surrounding bony landmarks. Corresponding coronal plates allow target determination in that plane. Intracerebral coordinates based on the position of the optic chiasma can be transformed into individual Horsley-Clarke coordinates. The error of the atlas is estimated as +/- 0.25 mm anteroposteriorly, +/- 0.1 mm coronally, and +/- 0.5 mm vertically.

Animals↗

Double-headed stereotaxic carrier apparatus for insertion of depth electrodes. Technical note.

A carrier device has been developed for use with a sterotaxic apparatus. It can be attached to the OBT frame or to any Leksell-type frame. With this carrier, intracranial insertion of commercially available depth electrodes with built-in connectors is possible. By using two different heads mounted on a single carrier, the surgeon can perform a transcutaneous twist-drill trephination and attach the screws through a chuck, adjust the device in the horizontal plane, and then insert and anchor the electrodes by using a small platform with a hinged roof.

Electrodes↗

[Digital roentgen-guided large-needle biopsy as an alternative to surgical biopsy in patients with nonpalpable mammographic abnormalities].

OBJECTIVE: To compare histopathological findings from stereotaxic needle core biopsies and from excision biopsies performed on patients with impalpable breast lesions suggestive of carcinoma. DESIGN: Prospective and descriptive, with a description of the stereotaxic needle core biopsy procedure. SETTING: Academic Hospital Utrecht, the Netherlands. METHODS: In 36 patients core biopsies were done with 14-gauge biopsy needles, followed by a localisation procedure with surgical biopsy. The pathological features of the core and excision specimens were compared. RESULTS: Results of 35 (97%) core biopsies corresponded to those of excision biopsies. Stereotaxic core biopsy was not possible due to technical problems in 2 cases. CONCLUSION: Stereotaxic core biopsy appears to be an acceptable alternative to excision biopsy.

Adult↗

Isocentric head fixation for microscopic neurosurgery.

The significance of isocentering in head fixation during micro-neurosurgery is described. The approach angle to the lesion could be changeable without adjusting the focus and placement of the operating microscope by rotating the head holder when the lesion is fixed at the isocenter of the rotatable.

Head↗

[Demonstration of the pulsatile secretion of LH-RH into hypophysial portal blood of ewes using an original technic for multiple samples].

Using a stereotaxic dorsal approach under lateral X-Ray control associated with a perfusion system, serial collections of hypophysial portal blood have been successfully obtained in three spayed ewes during 4 to 9 successive hrs. For the first time, pulsatile patterns of LH-RH secretion have been demonstrated in long term ovariectomized ewes. The frequency of LH-RH pulses recorded (about one pulse every 50 mn) agrees closely with the frequency of LH pulses in peripheral plasma of ovariectomized ewes. The technique allowed measurement of LH-RH in hypophysial portal blood thus providing a useful method for investigation of hypothalamo-pituitary gonadal interactions.

Animals↗