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[Echinococcosis of the spinal canal].

Among various forms of echinococcosis its location in the spinal canal and bone marrow affection are the rarest. Intravital diagnosis is complicated. As a rule, the disease manifests primarily with radicular syndrome followed by marrow compression, asymmetric compression of the roots of cauda equina and pelvic disfunction. The cerebrospinal fluid becomes xanthochromic with hyperalbuminosis and albuminocytologic dissociation. Myelography shows filling defect. Spinal x-ray examination detects specific changes of the vertebra and ossification foci. Unfavorable epidemiological situation may be indicative of probable infection and prompt a valid diagnosis. Surgery is advocated as the only adequate treatment.

Adolescent↗

Vertical stab wound to the lumbo-sacral spinal canal: report of a case.

A 63-year-old man was stabbed by an iron bar in the perineum. On admission, the external aspect of this wound appeared to be only a tiny hole. However, the bar had penetrated the rectum, sacrum, and lumbar spinal canal up to the third lumbar vertebral body. This patient was eventually treated with sacral wound drainage, a closure of the rectal wound, and pelvic drainage. Lumbar surgery was not performed because computed tomography (CT) and magnetic resonance imaging (MRI) did not show a progression of inflammatory changes in either the lumbar canal or perispinal hollow caused by the iron bar during the hospital stay. The clinical, CT, and MRI findings thus provided important information in the diagnosis and treatment of stab wounds.

Drainage↗

Acrodysostosis associated with spinal canal stenosis.

An adult case of acrodysostosis with striking lumbar spinal canal stenosis is reported. She complained of numbness on the right arm, intermittent claudication with numbness on both legs and pain and weakness on the left leg. Although the reduced lumbar interpedicular distance has been reported, no adult case with neurologic symptoms has been reported.

Adult↗

A unique occurrence of a cerebral atypical teratoid/rhabdoid tumor in an infant and a spinal canal primitive neuroectodermal tumor in her father.

This report describes the clinical, pathological, immunohistochemical and genetic data of two rare malignant neoplasms of the central nervous system (CNS)--a cerebral atypical teratoid/rhabdoid tumor (AT/RT) in a 5-month-old girl and a spinal canal primitive neuroectodermal tumor (PNET) in her father. Despite aggressive treatment, both tumors were fatal, displaying extensive local recurrence and diffuse neoplastic dissemination. The paraffin-embedded tumor tissue samples were analyzed using a dual-color FISH with a locus specific LSI22q (BCR) probe. In the AT/RT tissue, a loss of BCR locus was observed in a significant proportion of the cells in contrast to the PNET specimen where the majority of nuclei did not reveal any loss of the BCR region. No mutations in exon 5 and no changes in SNP of intron 5 of hSNF/INI1 gene were found. In addition, analysis of loss of heterozygosity (LOH) was performed using a panel of 15 microsatellite markers of chromosome 22. No LOH were found in both tumor tissues. In both cases no constitutional mutations of gene TP53 were found. Analysis of the TP53 mutations in the tumor tissues revealed that the PNET, not the AT/RT tumor, was homozygous for a missense mutation at codon 175 (CGC ==> CAC). Thus, our findings emphasize the genetic differences between the two specimens and suggest that the occurrence of these two aggressive tumors of CNS in one family could be coincidental.

Adult↗

Congenital spondylolysis of cervical vertebrae with spondylolisthesis anf frontal narrowing of the spinal canal. Report of two cases.

Two cases of cervical spondylolisthesis, due to a congenital defect in the pars interarticularis of C6, associated with spina bifida and elongation of the contralateral pars interarticularis, are reported. Tomography showed an abnormal direction of the articular facets of C6 and demonstrated a narrow frontal diameter of the cervical spinal canal at the level of the malformation. Gas myelography showed a slight compression of the cord. Unlike previously reported cases the patients had neurological findings which, in one case at least, were certainly referable to the spinal cord.

Adult↗

Needle aspiration of intramedullary and intradural extramedullary masses of the spinal canal.

Ten intramedullary and two intradural extramedullary masses of the spinal canal were evaluated with 16 separate needle aspirations. Cord fluctuance at air myelography and/or low density within the cord on computed tomography determined the level of aspiration. The condition of two patients with cystic neoplasms and one with syringohydromyelia improved after fluid removal. Endomyelography demonstrated the extent of eight intramedullary cavities. In syringohydromyelia, this information was used in determining the surgical approach. Aspiration and tissue biopsy enabled successful diagnosis of two cases of intradural extramedullary masses of unknown etiology. Needle aspiration yields valuable diagnostic information and is safe when proper guidelines are followed.

Adult↗

[Ischias without intervertebral disk prolapse: the compression of lumbar nerve roots in the lateral recess of the spinal canal].

In some cases with the clinical and myelographic diagnosis of lumbar root compression due to disc herniation, exploration fails to reveal any lesion of the intervertebral disc. Sometimes the source of the root compression is found to be articular: process impingement in stenotic recessus lateralis of the spinal canal. Pathogenesis and surgical therapy of such lesion are discussed. It is suggested that in such cases radical exposure of the nerve root should be undertaken, even if it should prove necessary to sacrifice articular facets.

Adolescent↗

[Spinal canal stenosis syndrome by venous collateralization of an inferior cava thrombosis].

We described in 1988 the case of a young patient with a right iliac vein and vena cava thrombosis who developed lubagoes and intermittent claudication of paralytic type. A digital venography by left femoral approach showed a derivation via the lumbar vein towards the spinal plexus. Later, the patient experienced a left external iliac vein thrombosis. Subsequently, collaterization went through the truncal veins and the clinical manifestations of the tight spinal canal disappeared. Since then, several cases of chronic thrombosis of the left primary iliac veins have been discovered. These also showed unexplained lumbagoes of the same duration. The idea of a relation of cause and effect was seldom accepted by the patients, which prevented us to proceed to many venous catherisms. Also, we performed only one operation until now: the cesarean of an ascending lumbar vein. In this very case, the tight spinal canal symptoms disappeared but appeared again after a few month-time for unknown reasons. Only one acute case has been found up to now: a woman who delivered by ligation suffered from lumbagoes and sciaticae. A dilatation of spinal veins and a lower vena cava thrombosis were showed by tomography. This woman had no leg symptom and lumbagoes disappeared with the partial recanalization of the cava.

Acute Disease↗

Remodeling of the spinal canal after thoracolumbar burst fractures.

Thirty-one patients with thoracolumbar burst fractures, seven untreated, 16 treated nonoperatively, and eight treated operatively, were analyzed retrospectively and followed up for 3 to 7 years. The initial and final degrees of neurologic deficit and the stenotic ratio of the spinal canal were recorded. Stenotic ratio significantly decreased from the first examination (range, 12.3%-74.5%; average, 26.2%) to the final followup (range, 5.4%-46.5%; average, 19.2%), but there were no differences of the percentage of remodeling between patients who were untreated and those treated nonoperatively and operatively. The recovery rate was highly significantly related to the stenotic ratio at first examination. Nonoperative management may be considered for treatment of patients who are neurologically intact or only slightly impaired with thoracolumbar burst fractures.

Adult↗

Computed tomography with metrizamide myelography to define the extent of spinal canal block due to tumor.

In five patients with complete spinal block due to tumor, CT was used to show the upper level of the block. In each case metrizamide myelography demonstrated the lower level of the block, but not enough metrizamide leaked past the block to allow myelographic identification of the upper level. However, the subarachnoid space both below and above the level of the block was clearly outlined by metrizamide on CT in each case.

Adolescent↗

Enterogenous cyst of the cervical spinal canal.

A case of an enterogenous cyst of the cervical spinal canal in an 18 year old man is presented, high-lighting the radiological findings. A brief overview is given of these rare cysts, together with their clinical and radiological features and associations.

Adolescent↗

Role of stenosis of spinal canal in L4-L5 nerve root compression assessed by flexion-extension myelography.

Myelographic flexion-extension studies were performed in four groups of 10 patients each, with (A) normal myelogram; (B) bilateral nerve root compression at L4-L5; (C) unilateral nerve root compression at L4-L5 and (D) nerve root compression at L5-S1. The aim of the investigation was to assess the role of spinal stenosis in contributing to nerve root compression. The results indicate that a form of stenosis of the spinal canal plays an important role in bilateral nerve root compression at L4-L5, and to a lesser extent in unilateral nerve root compression at L4-L5. It does not appear to play a role in L5-S1 nerve root compression (stenosis of the lateral recess left aside). It is advocated that in myelographic L4-L5 nerve root compression additional flexion-extension studies should be performed in order to evaluate the possible role of stenosis of the spinal canal contributing to this compression. Even in nerve root compression by disc extrusion, concomitant spinal stenosis may necessitate additional decompressive laminectomy.

Humans↗

Crohn's disease penetrating into the spinal canal.

An 11-year-old boy who had suffered from Crohn's disease of the large bowel for 4 years developed high fever, severe back pain and flexion-contracture of the right hip joint with inability to walk. After several weeks radicular irritation also became apparent. CT-scan demonstrated an abscess of the right psoas muscle that had also infiltrated the spinal canal, leading to a spinal extradural abscess extending from L2-S4. Therapy comprised surgical drainage of the psoas abscess and conservative therapy (mainly steroids and hypercaloric diet) and resulted in complete cure of the psoas and the spinal abscess. Spinal infiltration is a rare and serious complication of Crohn's disease and must be considered in every case of significant back pain with or without obvious neurological signs.

Abscess↗

[Neuroophthalmological complications through liquor leakage after surgical operation on the spinal canal for diagnostic i.e. therapeutic purposes (author's transl)].

The rare liquor leakage syndrome with cranial nerve lesion, which preferably affects the eye-muscle nerves, can be caused either by further leakage of liquor cerebrospinalis through the dura hole made by the lumbar puncture - or after a surgical operation on the spinal canal leaving a dura closure, which is not tight. This does not occur after a suboccipital puncture. A report is given on three cases with different eye-muscle paresis after a simple diagnostic lumbar puncture, after a lumbosacral myelography and after a resection of the sacral nerve roots including the filum terminale and caudal dural sac. The prognosis of the eye-muscle paresis is good. Restitutio ad integrum resulted. A fourth case with temporary loss of sight of one eye is reported after a lumbar air encephalography, but the eye nerves were damaged before as a result of previous tuberculous basal meningitis. Only partial recovery of the visual power occurred.

Adolescent↗